General Gynecology
RCT | Single-dose, bioadhesive Clindamycin 2% gel for bacterial vaginosis.
5 Jul, 2022 | 11:56h | UTCCommentary:
Single-Dose Clindamycin Gel Highly Effective for Bacterial Vaginosis – JAMA
Single-Dose Clindamycin Gel Highly Effective for Bacterial Vaginosis in Women – Medical Dialogues
Commentary on Twitter
FREE: Single-Dose, Bioadhesive Clindamycin 2% Gel for Bacterial Vaginosis: A Randomized Controlled Trial #obgyn https://t.co/ofIXGiFXbL pic.twitter.com/0nQigeCFP5
— The Green Journal (@greenjrnl) May 27, 2022
M-A | Antibiotics for preventing recurrent urinary tract infection.
4 Jul, 2022 | 12:17h | UTCInfertility, recurrent pregnancy loss, and risk of stroke: pooled analysis of individual patient data of 618 851 women.
27 Jun, 2022 | 11:59h | UTCNews Release: Infertility and pregnancy loss may increase women’s risk of stroke – BMJ Newsroom
Commentary on Twitter
Infertility and pregnancy loss are associated with an increased risk of non-fatal and fatal stroke in later life, finds study.
Early monitoring of women who have experienced miscarriage or stillbirth could lower the risk, the researchers suggest https://t.co/fYrNfpz6fC
— The BMJ (@bmj_latest) June 24, 2022
Cohort Study: The risk of stroke is substantially higher in the first year of initiation of oral contraceptives or hormone replacement therapy.
27 Jun, 2022 | 11:44h | UTCOral Contraceptives, Hormone Replacement Therapy, and Stroke Risk – Stroke (link to abstract – $ for full-text)
Commentary: Flash of Greater Stroke Risk at Initiation of Oral Contraceptives — Risk with hormone replacement therapy lingers in the long run, though – MedPage Today (free frustration required)
RCTs: Once daily oral relugolix combination therapy vs. placebo in patients with endometriosis-associated pain.
23 Jun, 2022 | 10:30h | UTCCommentaries:
Relugolix combination therapy for endometriosis pain – The Lancet (free registration required)
Commentary on Twitter
Treatment options for #endometriosis-associated pain are suboptimal.
Two new studies indicate once-daily relugolix combination therapy significantly improved pain and was well tolerated. 1/2 https://t.co/LBFgTMZSO2
— The Lancet (@TheLancet) June 21, 2022
International consensus statements on pre-invasive vulvar lesions.
23 Jun, 2022 | 10:21h | UTCNews Release: New Guidelines Address Treatment of Pre-Invasive Lesions of the Vulva – Wolters Kluwer Health: Lippincott
Review: Sex differences in sequelae from COVID-19 infection and in long COVID syndrome.
22 Jun, 2022 | 12:06h | UTCCommentary: Women more likely to have long COVID, different symptom profile – CIDRAP
M-A: Overweight/obesity in childhood and the risk of early puberty.
21 Jun, 2022 | 10:36h | UTCRelated Study: Patterns of Early Life Weight Gain and Female Onset of Puberty – Journal of the Endocrine Society
Opinion | Normalizing menopause – “Martha Hickey and colleagues argue that social and cultural attitudes contribute to the varied experience of menopause and that medicalization fuels negative perceptions”.
20 Jun, 2022 | 10:38h | UTCNormalizing menopause – The BMJ (free for a limited period)
News Release: Medicalizing menopause may be unhelpful for some women – British Medical Journal
Commentary: Menopause is not a disease. Experts call for new narrative for this natural stage of a woman’s life – CNN
The clinician’s guide to prevention and treatment of osteoporosis.
20 Jun, 2022 | 01:22h | UTCThe clinician’s guide to prevention and treatment of osteoporosis – Osteoporosis International
ESMO Guideline: Diagnosis, treatment, and follow-up of endometrial cancer.
13 Jun, 2022 | 08:08h | UTC
Systematic review: educational interventions to improve the menstrual health of young adolescent girls.
10 Jun, 2022 | 10:59h | UTC
[News release – not published yet] Women not being routinely informed that a common anesthetic may lessen contraception effectiveness, doctors warn.
9 Jun, 2022 | 11:31h | UTCCommentary: Women in UK ‘seldom’ told drug used in surgery can impede contraception – The Guardian
Screening every five years safe for women who test negative for HPV, study confirms.
9 Jun, 2022 | 11:26h | UTCNews Release: Screening every five years safe for women who test negative for HPV, study confirms – King’s College London
Editorial: HPV screening for cervical cancer is reaching maturity – The BMJ
Related WHO Guidance:
News release: New recommendations for screening and treatment to prevent cervical cancer – World Health Organization
Related USPSTF Guidance: Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement – JAMA
Cohort Study: Intrauterine device-related uterine perforation incidence and risk.
6 Jun, 2022 | 10:59h | UTCIntrauterine device-related uterine perforation incidence and risk (APEX-IUD): a large multisite cohort study – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Although the risk for uterine perforation with IUD insertion 4 days to 6 weeks or less postpartum is nearly 7x that of insertion non-postpartum, perforation remains an incredibly rare event for all clinical time pointshttps://t.co/DPqgLAh1Dx
— The Lancet (@TheLancet) June 3, 2022
Brief Review: Medication for early pregnancy termination.
3 Jun, 2022 | 11:06h | UTCMedication for Early Pregnancy Termination – JAMA (free for a limited period)
Note: Abortion is not legalized in Brazil and other countries.
RCT: Efficacy of bariatric surgery in treating women with obesity and polycystic ovary syndrome.
3 Jun, 2022 | 11:05h | UTC
A systematic review of the guidelines on venous thromboembolism prophylaxis in gynecologic oncology.
3 Jun, 2022 | 10:48h | UTC
Guidelines on stroke in women: management of menopause, pregnancy and postpartum.
2 Jun, 2022 | 11:27h | UTC
M-A: Association between benign ovarian tumors and ovarian cancer risk.
2 Jun, 2022 | 10:18h | UTC
Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta‐analysis.
1 Jun, 2022 | 11:09h | UTC
Commentary on Twitter (thread – click for more)
1) Hot off the press!
"Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta‐analysis"#Evidence suggests levonorgestrel‐releasing intrauterine system (LNG‐IUS) is the best first‐line treatment for reducing menstrual blood loss;
— Cochrane Gynaecology & Fertility (@CochraneCGF) May 31, 2022
Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomized controlled trials.
31 May, 2022 | 11:50h | UTCRelated Study: Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial – The Lancet AND Commentary: Expensive antiseptics and sutures do not reduce the risk of surgical infections – National Institute for Health and Care Research
Commentary from one of the authors on Twitter (thread – click for more)
1. Today: our @TheLancetInfDis meta-analysis based on @FalconRct – triclosan sutures and alcoholic skin prep to reduce surgical site infection.
Link to open access PDF:https://t.co/cj7yFdbNpB pic.twitter.com/VkKRaxCAtm
— Aneel Bhangu (@aneelbhangu) May 27, 2022
Most doctors still believe in prescribing unnecessary antibiotics to treat asymptomatic bacteriuria, study suggests.
31 May, 2022 | 11:31h | UTC
Commentary on Twitter
???@jamanetworkopen @dr_dmorgan et Al
In this survey study of 551 primary care clinicians, 392 (71%) reported that they would prescribe antibiotics for asymptomatic bacteriuria, shocking? #IDTwitter @BradSpellberg @DrToddLee @InfectiousDz @bwtrautnerhttps://t.co/tekcQVsfqk pic.twitter.com/1fRakHgjU7— Antibiotic Steward Bassam Ghanem?? (@ABsteward) May 27, 2022
Retrospective Cohort Study | Ovarian cancer detection in average-risk women: classic- versus nonclassic-appearing adnexal lesions.
30 May, 2022 | 10:58h | UTCNews Release: Researchers use ultrasound to predict ovarian cancer – Radiological Society of North America
Commentary: Appearance of Ovarian Lesions on Ultrasound May Predict Malignancy – HealthDay
Commentary on Twitter
Classifying adnexal lesion appearance as classic or nonclassic has high sensitivity and specificity for diagnosing malignancy in women at average risk for ovarian cancer. @BaranLab @drantil7 @kpatellippmann @katematuren @ayakamaya @hanna_zrad @LizSadowski https://t.co/6NphOIycMe pic.twitter.com/99DyWIHXwU
— Radiology (@radiology_rsna) March 28, 2022
Cohort Study: Analysis of antiemetic use after initiation of hormone therapy.
27 May, 2022 | 11:21h | UTCAnalysis of Antiemetic Use After Initiation of Hormone Therapy – JAMA Network Open