Global & Public Health (all articles)
Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient
15 Apr, 2021 | 06:51h | UTCPandemic Boosts an Old Idea—Bringing Acute Care to the Patient – JAMA
Related studies: Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates AND Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences – JAMA Internal Medicine
WHO Calls For Expanding Access To Insulin At Launch of Global Diabetes Compact
15 Apr, 2021 | 06:25h | UTCWHO Calls For Expanding Access To Insulin At Launch of Global Diabetes Compact – Health Policy Watch
News release: New WHO Global Compact to speed up action to tackle diabetes – World Health Organization
Guidance: WHO global diabetes compact – World Health Organization
USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening
14 Apr, 2021 | 01:47h | UTCVitamin D Deficiency in Adults: Screening – U.S. Preventive Services Task Force
Evidence Report: Screening for Vitamin D Deficiency in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Editorial: The USPSTF 2021 Recommendations on Screening for Asymptomatic Vitamin D Deficiency in Adults: The Challenge for Clinicians Continues – JAMA AND Why USPSTF Still Finds Insufficient Evidence to Support Screening for Vitamin D Deficiency – JAMA Network Open
JAMA Patient Page: Screening for Vitamin D Deficiency in Adults
Guidance: Using Ventilation and filtration to reduce aerosol transmission of COVID-19 in long-term care homes
15 Apr, 2021 | 06:54h | UTC
Commentary on Twitter
PHAC guidance updated yesterday emphasizes aerosol transmission (including fecal aerosol via toilet traps) and need for adequate ventilation and/or air cleaners (HEPA). We are getting there.@jljcolorado @linseymarr @kprather88 https://t.co/8hi77846cY
— David Fisman (@DFisman) April 14, 2021
Case Report: Thrombotic Thrombocytopenia after Johnson & Johnson Vaccine
15 Apr, 2021 | 07:02h | UTCThrombotic Thrombocytopenia after Ad26.COV2.S Vaccination – New England Journal of Medicine
Related: U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots AND 4 Things to Know About the J&J Covid Vaccine Pause – Kaiser Health News AND Why Johnson & Johnson shots were paused — and why that’s so confusing – Vox AND Is it the adenovirus vaccine technology, used by AstraZeneca and Johnson & Johnson, causing blood clots? There’s no evidence yet – The Conversation
Spatiotemporal pattern of COVID-19 spread in Brazil
15 Apr, 2021 | 07:06h | UTCSpatiotemporal pattern of COVID-19 spread in Brazil – Science
Commentary on Twitter
New @ScienceMagazine are 2 papers on covid in Brazil, documenting what fueled the emergence of the P.1 variant, along w/ its high transmissibility, possible increased lethality, incomplete protection from prior covidhttps://t.co/lIyz1ho57Nhttps://t.co/1dzfB6XKII @estercsabino pic.twitter.com/Ad0QVu1URL
— Eric Topol (@EricTopol) April 14, 2021
Opinion | Deep Cleaning Isn’t a Victimless Crime
15 Apr, 2021 | 06:56h | UTCDeep Cleaning Isn’t a Victimless Crime – The Atlantic
Related: CDC Updated Guidance: “It is possible for people to be infected through contact with contaminated surfaces or objects, but the risk is generally considered to be low” (CDC Guidance and more)
Observational study: Impact of the influenza vaccine on COVID-19 infection rates and severity
15 Apr, 2021 | 06:47h | UTCCommentary: Flu shot associated with fewer, less severe COVID cases – University of Michigan
Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients
15 Apr, 2021 | 06:49h | UTCCommentaries: Exercise may strongly protect against poor COVID-19 outcomes – CIDRAP AND One Good Way to Help Beat COVID: Exercise – HealthDay
New studies suggest SARS-CoV-2 variant B.1.1.7 is not more deadly, just more transmissible
14 Apr, 2021 | 02:12h | UTCCommentaries: Expert reaction to two papers looking at the transmissibility and severity of the B.1.1.7 variant – Science Media Centre AND UK coronavirus variant not more deadly, just spreads more easily, studies find – LiveScience
U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots
14 Apr, 2021 | 02:16h | UTCJoint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine – U.S. Food & Drug Administration
Commentaries: Covid-19: US suspends Johnson and Johnson vaccine rollout over blood clots – BMJ AND CDC and FDA recommend US pause use of Johnson & Johnson’s Covid-19 vaccine over blood clot concerns – CNN AND US halts J&J COVID vaccine after reports of blood clots – CIDRAP AND U.S. urges pause on use of Johnson & Johnson Covid-19 vaccine after rare blood clotting cases – CIDRAP
WHO, agencies urge countries to suspend sale of live wild mammals at markets
14 Apr, 2021 | 02:06h | UTCWHO, agencies urge countries to suspend sale of live wild mammals at markets – Reuters
Original Guidance: Reducing public health risks associated with the sale of live wild animals of mammalian species in traditional food markets – World Health Organization
Review: Vaccine development for emerging infectious diseases
14 Apr, 2021 | 02:01h | UTCVaccine development for emerging infectious diseases – Nature
Opinion | Coronavirus Variants Don’t Have to Be Scary. Still, Mask Up.
14 Apr, 2021 | 02:05h | UTCCoronavirus Variants Don’t Have to Be Scary. Still, Mask Up. – The New York Times
Commentary on Twitter
"Viruses undergo mutations frequently, both within infected people and as they travel from one person to another," @EricTopol writes. "That’s why it’s important to remember this (modified) adage: All variants are innocent until proven guilty." https://t.co/Ju60zb5gST
— New York Times Opinion (@nytopinion) April 13, 2021
RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19
13 Apr, 2021 | 05:30h | UTCOriginal study (preprint): Inhaled budesonide for COVID-19 in people at higher risk of adverse outcomes in the community: interim analyses from the PRINCIPLE trial – medRxiv
Commentary: Covid: Asthma drug ‘speeds up recovery at home’ – BBC
Related study: Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19 (study and commentaries)
Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19
14 Apr, 2021 | 01:59h | UTCCommentary: CDC: 1 in 3 children hospitalized with COVID-19 requires treatment in ICU – UPI AND 12% of Children with COVID Are Hospitalized: Study – WebMD
Commentary on Twitter
Of 2430 pediatric patients who were hospitalized with COVID-19, 756 (31.1%) experienced severe COVID-19. Severe disease was more common in patients with chronic conditions, in male patients, and in children aged 2-11 years vs children aged 12-18 years. https://t.co/3fmlCFsmo8
— COVID Reference (@CovidReference) April 10, 2021
Tobacco Taxes Are Most Effective Yet Least Implemented Tactics, Says WHO
13 Apr, 2021 | 05:06h | UTCTobacco Taxes Are Most Effective Yet Least Implemented Tactics, Says WHO – Health Policy Watch
Guidance: WHO technical manual on tobacco tax administration – World Health Organization
Infectivity of severe acute respiratory syndrome coronavirus 2 in children compared with adults
13 Apr, 2021 | 05:27h | UTCCommentary: Children may be less infectious in spreading SARS-CoV-2 to others – News Medical
China considers mixing COVID-19 vaccines to boost protection rate
13 Apr, 2021 | 05:24h | UTCChina considers mixing COVID-19 vaccines to boost protection rate – Reuters
[Press release – not published yet] Phase 3 prevention trial showed 81% reduced risk of symptomatic SARS-CoV-2 infections with subcutaneous administration of monoclonal antibodies
13 Apr, 2021 | 05:26h | UTCCommentaries: Regeneron says antibody cocktail prevented Covid when given as simple injection, not an IV – STAT AND Regeneron’s Covid mAb as a prophylactic injection: Reduced risk of symptomatic infection by 81% – Endpoint News
Cohort study: SARS-CoV-2 infection rates of antibody-positive vs. antibody-negative health-care workers – previous infection was associated with 84% lower risk of (re)infection
12 Apr, 2021 | 01:30h | UTCCommentary: Correlates of protection from SARS-CoV-2 infection – The Lancet
Commentary on Twitter
💥SIREN STUDY💥 @TheLancet
Previous SARS-CoV-2 infection
provides protection similar to or even better than currently used vaccines
📌84% risk reduction(RR) for reinfection
📌93% RR for those w symptomatic infections
📌B.1.1.7 circulate during the studyhttps://t.co/uQ3M9yahAv pic.twitter.com/leQCNbmHQO— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 10, 2021
Perspective | They Tested Negative for Covid. Still, They Have Long Covid Symptoms.
13 Apr, 2021 | 05:23h | UTCThey Tested Negative for Covid. Still, They Have Long Covid Symptoms. – Kaiser Health News
Commentary on Twitter
Scary: Many people have tested negative for SARSCoV2, yet they developed Long Covid. What's to blame? Haphazard testing protocols, delays & difficulties accessing tests & poor quality of many of the tests on the market. All have have left people without proof of infection. https://t.co/KH3QYkbbKW pic.twitter.com/MVuRhWoHle
— delthia ricks 🔬 (@DelthiaRicks) April 12, 2021
[Preprint] Pfizer vaccine less effective for SARS-CoV-2 variant B.1.351
12 Apr, 2021 | 01:26h | UTCCommentaries: South African variant may evade protection from Pfizer vaccine, Israeli study says – Reuters AND Israeli data shows South African variant able to ‘break through’ Pfizer vaccine – The Times of Israel
Related: Another study indicates SARS-CoV-2 variant B.1.351, but not variant B.1.1.7, has partial resistance to neutralizing antibodies generated by natural infection or mRNA vaccination AND SARS-CoV-2 variants B.1.351 and P.1 can escape from therapeutic antibodies and evade antibodies induced by infection or mRNA vaccination AND B.1.351 strain of SARS-CoV-2 neutralization titer reduced 8- to 9-fold for Pfizer and AstraZeneca vaccinees. Convalescent plasma and therapeutic antibodies were less effective against this variant as well.
[Preprint] Efficacy and safety of CoronaVac in healthcare professionals in Brazil
12 Apr, 2021 | 01:17h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/hildabast/status/1381366467665391619
Viewpoint | Reducing Low-Value Care and Improving Health Care Value
9 Apr, 2021 | 03:23h | UTCReducing Low-Value Care and Improving Health Care Value – JAMA (free for a limited period)