Global & Public Health (all articles) | Page 77 of 252 | Links Medicus Content Curation & Alerts in Medicine

Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal

25 Apr, 2021 | 21:17h | UTC

News release: Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal – University of Oxford

Original study (preprint): High Efficacy of a Low Dose Candidate Malaria Vaccine, R21 in 1 Adjuvant Matrix-M™, with Seasonal Administration to Children in Burkina Faso – The Lancet

Commentaries: Malaria vaccine hailed as potential breakthrough – BBC AND Oxford Malaria vaccine proves highly effective in Burkina Faso trial – The Guardian

Commentary on Twitter (thread – click for more)

💡AMAZING—First high >75% efficacy vaccine for a disease with 229 million cases & 409,000 deaths worldwide in 2019 —#Malaria!

Created by Oxford, produced by Serum Institute of India, & supporting adjuvant by Novavax, SII expects to make 200 mil doses a year!

Science! #vaccine pic.twitter.com/gnPMvXxww6

— Eric Feigl-Ding (@DrEricDing) April 23, 2021

Resurgence of SARS-CoV-2: detection by community viral surveillance

25 Apr, 2021 | 21:55h | UTC

Resurgence of SARS-CoV-2: detection by community viral surveillance – Science

Commentary on Twitter

A #SARSCoV2 surveillance program tested in England in 2020 successfully detected a resurgence of virus infection at low prevalence, @imperialcollege researchers say. Such programs can augment routine surveillance to inform public health interventions. https://t.co/veilAJ8YX4 pic.twitter.com/9YFQbvtqbw

— Science Magazine (@ScienceMagazine) April 23, 2021

Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized

23 Apr, 2021 | 08:48h | UTC

High-dimensional characterization of post-acute sequalae of COVID-19 – Nature

Commentary: Among COVID-19 survivors, an increased risk of death, serious illness – Washington University School of Medicine

Commentary on Twitter (thread – click for more)

Happy to share the latest paper from our team in @nature

A comprehensive characterization of post acute sequelae of COVID-19#longcovid #PASC https://t.co/AGLnYCamWe @VAResearch @vahsrd @WUSTL @WUSTLpubhealth @WUSTLmed @WUSTLnews @VREFSTL @Biostayan @BCBowe

— Ziyad Al-Aly, MD (@zalaly) April 22, 2021

NIH Updates COVID-19 Treatment Guidelines – adds recommendations on colchicine, fluvoxamine, and monoclonal antibodies

23 Apr, 2021 | 08:46h | UTC

NIH Coronavirus Disease 2019 (COVID-19)
Treatment Guidelines – National Institutes of Health

Covid-19: More data on the increased risks to pregnant women and their newborn infants

23 Apr, 2021 | 08:44h | UTC

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study – JAMA Pediatrics

Editorial: COVID-19 in Pregnant Women and Their Newborn Infants

Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN

Commentary on Twitter

18 country study in >2000 pregnant women with and without #COVID19 shows higher complication and death rates in symptomatic, but not asymptomatic, women with COVID-19. Their babies were at greater risk of neonatal complications, mainly due to preterm birth https://t.co/mRl8OOIMsz

— JAMA Pediatrics (@JAMAPediatrics) April 22, 2021

RCT: Single-Dose Johnson & Johnson Vaccine has 85% efficacy against severe/critical Covid-19 and maintains efficacy against variant B.1.351

22 Apr, 2021 | 08:50h | UTC

Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19 – New England Journal of Medicine

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

22 Apr, 2021 | 08:49h | UTC

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons – New England Journal of Medicine

Audio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine

Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News

Covid-19: What do we know about airborne transmission of SARS-CoV-2?

23 Apr, 2021 | 08:33h | UTC

Covid-19: What do we know about airborne transmission of SARS-CoV-2? – The BMJ

COVID vaccines and kids: five questions as trials begin

23 Apr, 2021 | 08:37h | UTC

COVID vaccines and kids: five questions as trials begin – Nature

Ahead of World Malaria Day, WHO launches effort to stamp out malaria in 25 more countries by 2025

22 Apr, 2021 | 08:23h | UTC

World Malaria Day: WHO launches effort to stamp out malaria in 25 more countries by 2025 – World Health Organization

Report: Zeroing in on malaria elimination: Final report of the E-2020 initiative – World Health Organization

Vaccine Breakthrough Infections with SARS-CoV-2 Variants

22 Apr, 2021 | 08:47h | UTC

Vaccine Breakthrough Infections with SARS-CoV-2 Variants – New England Journal of Medicine

Commentary on Twitter

Mild #COVID19 symptoms developed in two fully vaccinated persons. Serum tests showed high titers of antibodies capable of neutralizing the wild-type strain of #SARSCoV2 first identified in Wuhan, China, but sequencing of the virus isolates revealed novel variants.

— NEJM (@NEJM) April 21, 2021

A year in the COVID-19 vaccine scheme COVAX

22 Apr, 2021 | 08:43h | UTC

A year in the COVID-19 vaccine scheme COVAX – Reuters

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

22 Apr, 2021 | 08:40h | UTC

Post-acute COVID-19 outcomes in children with mild and asymptomatic disease – The Lancet Child & Adolescent Health

Commentaries on Twitter

Early data from @RCHMelbourne show that, at 3-6 month follow-up, all 151 children with mild and asymptomatic #COVID19 had returned to their baseline health status and post-acute COVID-19 symptoms had resolved.

Letter from @Shidan_Tosif & colleagues: https://t.co/XXa0EPIgPY

— The Lancet Child & Adolescent Health (@LancetChildAdol) April 20, 2021

Given such little available data, this study from Australia on post-acute COVID-19 symptoms in children is very important

Findings are extremely reassuring

Post-acute symptoms were rare, and mild (cough 4%, fatigue 2%, cough and fatigue 1%)

Great news!https://t.co/TEJyES3Crx

— Alasdair Munro (@apsmunro) April 21, 2021

Great to see research looking at whether long Covid is a problem in children.

From this Melbourne cohort, enduring cough and fatigue are uncommon.

It hasn’t been clear to me whether borders will reopen before children are vaccinated so this is VIP https://t.co/iLXqwXJmOt

— Jin Russell (@DrJinRussell) April 21, 2021

Truly encouraging data on post-acute #COVID19 in children. Single-center in Australia. n=151.
8% post-acute symptoms – all symptomatic COVID-19.
Mild symptoms: cough 4%, fatigue 2%, both 1%. Duration: cough 3-8w; post-viral fatigue 6-8w. All solved in follow-up time 3-6 months. https://t.co/vKrEFZlw3C

— Pablo Guisado Vasco (@PabloGVasco) April 21, 2021

Perspective | Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe.

22 Apr, 2021 | 08:38h | UTC

Do Kids Really Need to Be Vaccinated for Covid? Yes. No. Maybe. – Undark

Commentary on Twitter

Great article by @Sara_Talpos
key qs:
1 Does a kid need to be vaccinated for their sake?
2 Does a kid need to be vaccinated to protect adults who decline?
3. Does a kid need to be vaccinated to protect adults who were vax'd?

1/2https://t.co/6WpbttIiDo

— Vinay Prasad MD MPH (@VPrasadMDMPH) April 20, 2021