Global & Public Health (all articles)
The tangled history of mRNA vaccines.
15 Sep, 2021 | 09:06h | UTCThe tangled history of mRNA vaccines – Nature
Related:
mRNA vaccines for infectious diseases: principles, delivery and clinical translation.
Commentary on Twitter
What an outstanding ★ feature on the long history of mRNA vaccines and their future potential, by @ElieDolgin @Nature https://t.co/PZ1eFFnRsi pic.twitter.com/CjeS4vq0gx
— Eric Topol (@EricTopol) September 14, 2021
How COVID is derailing the fight against HIV, TB and malaria.
15 Sep, 2021 | 09:01h | UTCHow COVID is derailing the fight against HIV, TB and malaria – Nature
Related:
How COVID hurt the fight against other dangerous diseases
World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis
The USPSTF maintains the recommendation to screen for chlamydia and gonorrhea in all sexually active women 24 years or younger and in women 25 years or older who are at increased risk for infection.
15 Sep, 2021 | 08:57h | UTCEditorial: Screening for Chlamydia and Gonorrhea – JAMA
Evidence Report : Screening for Chlamydial and Gonococcal Infections: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Author Interview: USPSTF Recommendation: Screening for Chlamydia and Gonorrhea
JAMA Patient Page: Screening for Chlamydia and Gonorrhea
Report: Fully vaccinated people account for 1.2% of England’s Covid-19 deaths.
14 Sep, 2021 | 10:07h | UTCFully vaccinated people account for 1.2% of England’s Covid-19 deaths – The Guardian
Original Report: Deaths involving COVID-19 by vaccination status, England: deaths occurring between 2 January and 2 July 2021 – Office for National Statistics
COVID-19 vaccine efficacy does not support boosters for general population, review concludes.
14 Sep, 2021 | 10:08h | UTCNews release: COVID-19 vaccine efficacy does not support boosters for general population, review concludes – The Lancet
Original article: Considerations in boosting COVID-19 vaccine immune responses – The Lancet
Commentaries:
FDA experts among group opposing US booster shot plan – Associated Press
FDA vaccine regulators argue against Covid-19 vaccine boosters in new international review – STAT
Global experts pan wider use of COVID vaccine booster dose – CIDRAP
Boosters Are ‘Not Appropriate’ – Reach Unvaccinated First – Health Policy Watch
Data Doesn’t Support Need for COVID-19 Vaccine Boosters: Experts – HealthDay
Covid: Single jab recommended for 12 to 15-year-olds by UK’s top doctors.
14 Sep, 2021 | 10:05h | UTCCovid: Single jab recommended for 12 to 15-year-olds by UK’s top doctors – BBC
See also: Covid-19: Children aged 12-15 should be offered vaccine, say UK’s chief medical officers – The BMJ
Massive numbers of new COVID–19 infections, not vaccines, are the main driver of new coronavirus variants.
14 Sep, 2021 | 09:56h | UTC
Review | The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology.
14 Sep, 2021 | 09:58h | UTCThe next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology – Nature Medicine
Commentary on Twitter
Important paper. Monitoring virus evolution and assessing variants is critical to guide the response.
Science, collaboration, analyses, sharing, discussion, action, repeat
Proud @WHO provided technical and financial support for it. #COVID19 https://t.co/M7v8dmIy6q https://t.co/j1VOgBhw6Y
— Maria Van Kerkhove (@mvankerkhove) September 10, 2021
Vaccines Will Not Produce Worse Variants.
14 Sep, 2021 | 09:53h | UTCVaccines Will Not Produce Worse Variants – Science
Four factors that increase the risk of vaccinated people getting COVID.
12 Sep, 2021 | 22:02h | UTCFour factors that increase the risk of vaccinated people getting COVID – The Conversation
What’s the evidence for COVID-19 booster shots?
12 Sep, 2021 | 22:05h | UTCWhat’s the evidence for COVID-19 booster shots? – Canadian Medical Association Journal
Perspective | We’re Asking the Impossible of Vaccines – “Complete protection against infection has long been hailed as the holy grail of vaccination. It might simply be unachievable”.
12 Sep, 2021 | 21:59h | UTCWe’re Asking the Impossible of Vaccines – The Atlantic
Commentary on Twitter
A really great read from @KatherineJWu on why it may be too much to expect vaccines—#covid19 or otherwise—to prevent infection. Still the vaccines are great at what we need—preventing hospitalizations and deaths! https://t.co/ufVBVn4wd1
— Jennifer Nuzzo, DrPH (@JenniferNuzzo) September 11, 2021
Risk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions.
12 Sep, 2021 | 22:03h | UTCRisk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions – CNN
Original study: Hospitalisation among vaccine breakthrough COVID-19 infections – The Lancet Infectious Diseases
News release: Study examines severe breakthrough cases of COVID-19 – YaleNews
Commentary on Twitter
New Comment: Hospitalisation among vaccine breakthrough #COVID19 infections https://t.co/1MtOoO8HVV, by Prerak V Juthani, @hyungjchun, and colleagues pic.twitter.com/mYAAEzHLDL
— The Lancet Infectious Diseases (@TheLancetInfDis) September 8, 2021
Perspective | How Endemic COVID Becomes a Manageable Risk – “Businesses and schools must adapt, because the dual threat from the coronavirus and the flu will be too severe”.
12 Sep, 2021 | 21:58h | UTCHow Endemic COVID Becomes a Manageable Risk – The Atlantic
Commentary on Twitter
.@TheAtlantic /@ScottGottliebMD — How Endemic COVID Becomes a Manageable Risk/We’re not going to annihilate COVID. Instead, our goal must be to weaken its punch so that it becomes a risk we can adapt to. https://t.co/TEX5kxBMO2
— Greg Folkers 🇺🇦☮️🇺🇸 (@greg_folkers) September 12, 2021
The Delta Covid variant and children: transmission in kids is low and only 2% hospitalized, report finds.
12 Sep, 2021 | 21:56h | UTCNews release: COVID-19 Delta variant in schools and early childhood education and care services in NSW, Australia: 16 June to 31 July 2021
Commentary on Twitter (thread – click for more)
Amazing education settings outbreak data from the Delta #COVID19 outbreak in NSW 🇦🇺
Primary/Secondary schools mostly closed, so limited info to draw on (Attack rate v low, <2%)
BUT early years settings fully open with no masks!
What happened? 🧵https://t.co/mG05e5Mp3T
1/
— Alasdair Munro (@apsmunro) September 8, 2021
Face masks for COVID pass their largest test yet – “A rigorous study finds that surgical masks are highly protective, but cloth masks fall short”.
10 Sep, 2021 | 05:36h | UTCFace masks for COVID pass their largest test yet – Nature
Original study: [Preprint] Largest study of masks yet details their importance in fighting Covid-19.
Commentary on Twitter
Face masks for COVID pass their largest test yet – I & others comment. It is true that I bought pink surgical masks (my favorite color) in response to this study for when I am around unvaccinated adults (or indoor public spaces for now)https://t.co/nFhlcqwrjv
— Monica Gandhi MD, MPH (@MonicaGandhi9) September 9, 2021
India’s DNA COVID vaccine is a world first – more are coming.
10 Sep, 2021 | 05:30h | UTCIndia’s DNA COVID vaccine is a world first – more are coming – Nature
Economic impact of tuberculosis mortality in 120 countries and the cost of not achieving the Sustainable Development Goals tuberculosis targets: a full-income analysis.
10 Sep, 2021 | 05:18h | UTCInvited Commentary: The incalculable costs of tuberculosis
Commentaries on Twitter
A strong eeconomic case for ending TB – trillions of dollars in savings. Cost of not acting now is going to be too expensive! @StopTB https://t.co/ffLVTeqOkj
— Suvanand Sahu (@SahuSuvanand) September 5, 2021
Failure to achieve the SDG tuberculosis mortality target by 2030 will lead to profound economic and health losses:
$3·0 trillion will be lost if the target is not met until 2045!!
Sachil Silva, Nim Pathy, @mikereidmd @DrEricGoosby @RifatAtun https://t.co/ipm5vj62IQ @LancetGH pic.twitter.com/fPHDW5eJWE
— Madhu Pai, MD, PhD (@paimadhu) September 3, 2021
[Preprint] Ineffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera.
9 Sep, 2021 | 10:02h | UTCIneffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera – bioRxiv
Related: United States boosts tracking of coronavirus strains as Mu variant draws scrutiny – Science
Commentary on Twitter (thread – click for more)
📍Bad news on #MuVariant—Japanese scientists: "Mu variant is highly resistant to sera from convalescent & [Pfizer]-vaccinated people. Direct comparison of different spike proteins revealed that Mu spike is more resistant…than all other current variants”🧵https://t.co/Ilf5gh3OGd pic.twitter.com/DbdJVGZTjz
— Eric Feigl-Ding (@DrEricDing) September 8, 2021
Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.
9 Sep, 2021 | 10:04h | UTCStudy 1: Spontaneous Abortion Following COVID-19 Vaccination During Pregnancy – JAMA
Study 2: Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion – New England Journal of Medicine
Commentary on Twitter
📣 NO LINK BETWEEN MISCARRIAGE & COVID VACCINATION
This @JAMA_current study examined 105446 pregnancies, including 13160 miscarriages
Women with pregnancies ending in miscarriage were NOT more likely to have had 💉 in prior 28 days than those that didnthttps://t.co/7cFELq1oPM
— Ilan Schwartz is on🦋 (@GermHunterMD) September 8, 2021
[Preprint] RCT: Additional heterologous vs. homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination.
9 Sep, 2021 | 09:55h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/hildabast/status/1435720202147143680
AstraZeneca bosses warn against rush for boosters – “giving the most vulnerable, who may not have built up a full immune response from the first two, a third, top-up dose is “sensible”. But any decision to give a third, booster jab “to large swathes of the population”, to extend their protection from the first two, must be based on clinical data”.
9 Sep, 2021 | 09:59h | UTCAstraZeneca bosses warn against rush for boosters – BBC
Commentary on Twitter (thread – click for more)
"Moving too quickly to boost across the entire adult population will deprive us of these insights, leaving this important decision to rest on limited data," Mr Soriot and Sir Mene write.https://t.co/xTAk7yyu5G
— The Sharing Scientist (@ScienceShared) September 8, 2021
WHO appeals for countries to postpone COVID-19 vaccine boosters until 2022 to prioritize vaccinating the most at-risk people around the world who are yet to receive their first dose.
9 Sep, 2021 | 10:00h | UTCSee also:
WHO chief urges halt to booster shots for rest of the year – Associated Press
WHO extends moratorium on booster COVID vaccine doses – CIDRAP
Perspective | The plan to stop every respiratory virus at once – “The benefits of ventilation reach far beyond the coronavirus. What if we stop taking colds and flus for granted, too?”
9 Sep, 2021 | 09:54h | UTCThe Plan to Stop Every Respiratory Virus at Once – The Atlantic
Related:
Recommendations for ventilation of indoor spaces to reduce COVID-19 transmission.
We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt.
WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19
CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk
Balancing incentives and disincentives for vaccination in a pandemic.
9 Sep, 2021 | 09:52h | UTCBalancing incentives and disincentives for vaccination in a pandemic – Nature Medicine