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Global & Public Health (all articles)

AHA Scientific Statement: Medication Adherence and Blood Pressure Control.

12 Oct, 2021 | 00:09h | UTC

Medication Adherence and Blood Pressure Control: A Scientific Statement From the American Heart Association – Hypertension

News release: Health system crucial to improve medication adherence for people managing hypertension – American Heart Association

Top Things to Know: Medication Adherence and Blood Pressure Control – American Heart Association

Commentary: Medication Adherence – Is It Really the Patient’s Fault? – American Heart Association

 


Kids are losing school days to quarantines. Here’s a way to keep them in classrooms – “Test-to-stay could dramatically reduce close contact quarantines”.

10 Oct, 2021 | 21:52h | UTC

Kids are losing school days to quarantines. Here’s a way to keep them in classrooms – NPR

Related study: Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

 


New Global Burden of Disease analyses show depression and anxiety among the top causes of health burden worldwide, and a significant increase due to the COVID-19 pandemic.

10 Oct, 2021 | 21:57h | UTC

News release: New Global Burden of Disease analyses show depression and anxiety among the top causes of health burden worldwide, and a significant increase due to the COVID-19 pandemic – Institute for Health Metrics and Evaluation

Original study: Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic – The Lancet

Commentaries:

Depression and anxiety disorders during the COVID-19 pandemic: knowns and unknowns – The Lancet

COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020: study – The Lancet

Covid crisis dramatically worsened global mental health, study finds – The Guardian

 

Commentary on Twitter (thread – click for more)

 


Heart-inflammation risk from Pfizer COVID vaccine is very low.

10 Oct, 2021 | 21:42h | UTC

Heart-inflammation risk from Pfizer COVID vaccine is very low – Nature

Original studies:

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

 


[Preprint] COVID-19 in children due to SARS-CoV-2 Delta strain resembles illness due to the Alpha variant, with short duration and similar symptom burden.

10 Oct, 2021 | 21:44h | UTC

Illness characteristics of COVID-19 in children infected with the SARS-CoV-2 Delta variant – medRxiv

 

Commentary on Twitter

 


Bioethics | The Trolley Problem and Vaccinating Young People Against COVID-19.

10 Oct, 2021 | 21:50h | UTC

The Trolley Problem and Vaccinating Young People Against COVID-19 – Science-Based Medicine

 


WHO report highlights global shortfall in investment in mental health.

10 Oct, 2021 | 21:39h | UTC

WHO report highlights global shortfall in investment in mental health – World Health Organization

Report: Mental Health ATLAS 2020 – World Health Organization

See also: World Mental Health Day 2021: Mental health care for all: let’s make it a reality – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


World Mental Health Day: prioritize social justice, not only access to care.

10 Oct, 2021 | 21:37h | UTC

World Mental Health Day: prioritise social justice, not only access to care – The Lancet (free registration required)

 

Commentary on Twitter

 


M-A: Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression.

10 Oct, 2021 | 21:34h | UTC

Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression: updated systematic review and individual participant data meta-analysis – The BMJ

See calculator: PHQ-9 (Patient Health Questionnaire-9)

 

Commentary on Twitter

 


WHO Guidance: Antigen-detection in the diagnosis of SARS-CoV-2 infection.

8 Oct, 2021 | 10:47h | UTC

Antigen-detection in the diagnosis of SARS-CoV-2 infection – World Health Organization

Related infographics:

Use of antigen detection rapid diagnostic testing – World Health Organization

Diagnostic testing for SARS-CoV-2 infection – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


Editorial: Brain health and its social determinants.

10 Oct, 2021 | 21:35h | UTC

Brain health and its social determinants – The Lancet

 

Commentary on Twitter

 


WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).

8 Oct, 2021 | 10:45h | UTC

A clinical case definition of post COVID-19 condition by a Delphi consensus, 6 October 2021 – World Health Organization

Related:

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)

 

Commentary on Twitter (thread – click for more)

 


WHO Launches Strategy to Achieve Global Covid-19 Vaccination by mid-2022.

8 Oct, 2021 | 10:41h | UTC

Strategy to Achieve Global Covid-19 Vaccination by mid-2022 – World Health Organization

News release: WHO, UN set out steps to meet world COVID vaccination targets – World Health Organization

Commentaries:

WHO Believes 70% Vaccination Target is Possible – But Only if Wealthy Countries Make Way for COVAX and Africa – Health Policy Watch

WHO launches global COVID vaccination strategy – CIDRAP

 


Study shows an increased risk of Guillain-Barré Syndrome with the J&J vaccine; the estimated observed to expected rate ratio was 4.18 for the 42-day window.

8 Oct, 2021 | 10:40h | UTC

Association of Receipt of the Ad26.COV2.S COVID-19 Vaccine With Presumptive Guillain-Barré Syndrome, February-July 2021 – JAMA

 

Commentary on Twitter

 


Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

8 Oct, 2021 | 10:29h | UTC

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination, March−June 2021, England – Eurosurveillance

Related:

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

 

Commentary on Twitter

 


Ivermectin: How false science created a Covid ‘miracle’ drug.

8 Oct, 2021 | 10:24h | UTC

Ivermectin: How false science created a Covid ‘miracle’ drug – BBC

 

Commentary on Twitter

 


How the risk of Covid-19 for kids compares to other dangers.

8 Oct, 2021 | 10:26h | UTC

How the risk of Covid-19 for kids compares to other dangers – Vox

 


Bioethics | People who want organ transplants must get the COVID-19 vaccine, a hospital says.

8 Oct, 2021 | 10:21h | UTC

People who want organ transplants must get the COVID-19 vaccine, a hospital say – NPR

 


Opinion | Covid-19 keeps delivering lessons about health care worker burnout. Will we learn them?

8 Oct, 2021 | 10:18h | UTC

Covid-19 keeps delivering lessons about health care worker burnout. Will we learn them? – STAT

 

Commentary on Twitter

 


U.S. Data: Drug-resistant Infections led to $1.9 billion in health care costs, more than 10,000 deaths among older adults in one year.

8 Oct, 2021 | 10:11h | UTC

News release: Drug-resistant Infections Led to $1.9 Billion in Health Care Costs, More Than 10,000 Deaths Among Older Adults in One Year – Infectious Diseases Society of America

Original study: Mortality, Length of Stay, and Healthcare Costs Associated With Multidrug-Resistant Bacterial Infections Among Elderly Hospitalized Patients in the United States – Clinical Infectious Diseases

Commentaries:

Urgent, Comprehensive Federal Action Needed To Stem Mortality and Medicare Costs Associated With Antimicrobial Resistance – Clinical Infectious Diseases

Study highlights impact of antibiotic resistance on older Americans – CIDRAP

 


Observational study in Qatar showed the effectiveness of Pfizer vaccine against any SARS-CoV-2 infection dropped to 20% in months 5 through 7 after the second dose, but effectiveness against severe Covid-19 remained high.

7 Oct, 2021 | 10:55h | UTC

Waning of BNT162b2 Vaccine Protection against SARS-CoV-2 Infection in Qatar – New England Journal of Medicine

Related: Cohort study: Pfizer vaccine effectiveness against any infections declined from 88% during the first month after full vaccination to 47% after 5 months. Vaccine effectiveness against hospital admissions remained high; 87% within 1 month, and 88% at 5 months after full vaccination, with no significant waning.

 

Commentary on Twitter

 


Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

7 Oct, 2021 | 10:51h | UTC

Myocarditis after Covid-19 Vaccination in a Large Health Care Organization – New England Journal of Medicine

Commentary: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD

Related Study: Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine

 

Commentaries on Twitter

 


Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

7 Oct, 2021 | 10:49h | UTC

Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine

Commentary: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD

Related study: Myocarditis after Covid-19 Vaccination in a Large Health Care Organization – New England Journal of Medicine

 

Commentaries on Twitter

 


Systematic Review: Administration of antimalarial drugs to whole populations for reducing malaria.

7 Oct, 2021 | 10:36h | UTC

Administration of antimalarial drugs to whole populations for reducing malaria – Cochrane Library

Original study: Mass drug administration for malaria – Cochrane Library

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1444724442094088195

 


Perspective | No one is safe until we are all safe.

7 Oct, 2021 | 10:47h | UTC

No one is safe until we are all safe – Science Translational Medicine

Commentary: Covid ‘still running rampant’ worldwide, warns creator of Oxford vaccine – The Guardian

Related: Opinion: Vaccine Nationalism Harms Everyone and Protects No One

 

Commentary on Twitter

 


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