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Global & Public Health (all articles)

[News release – not published yet] New guidelines from WHO recommend a simpler, safer treatment for cryptococcal disease in people living with HIV.

21 Apr, 2022 | 10:28h | UTC

New guidelines from WHO recommend a simpler, safer treatment for cryptococcal disease in people living with HIV – World Health Organization

Related Study: Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis – New England Journal of Medicine (link to abstract – $ for full-text)

 


Cohort study: COVID-19 infection granted patients strong and long-lasting protection from reinfection.

21 Apr, 2022 | 10:20h | UTC

News Release: COVID-19 infection granted patients strong and long-lasting protection from reinfection – Providence Health & Services

Original Study: Rates of COVID-19 Among Unvaccinated Adults With Prior COVID-19 – JAMA Network Open

Commentary: COVID-19 infection may offer similar immunity as vaccination – CIDRAP

 

Commentary on Twitter

 


Covid hasn’t given up all its secrets. Here are 6 mysteries experts hope to unravel.

20 Apr, 2022 | 09:57h | UTC

Covid hasn’t given up all its secrets. Here are 6 mysteries experts hope to unravel – STAT

 


Cohort Study: Rates and causes of mortality among children and young people with and without intellectual disabilities in Scotland.

20 Apr, 2022 | 09:22h | UTC

Rates and causes of mortality among children and young people with and without intellectual disabilities in Scotland: a record linkage cohort study of 796 190 school children – BMJ Open

 

Commentary on Twitter

 


National, regional, and global estimates of anemia by severity in women and children for 2000–19.

20 Apr, 2022 | 09:25h | UTC

National, regional, and global estimates of anaemia by severity in women and children for 2000–19: a pooled analysis of population-representative data – The Lancet Global Health

Invited Commentary: Sustainable Development Goals for anaemia: 20 years later, where are we now? – The Lancet Global Health

 


Omicron-specific Sinopharm, Sinovac COVID vaccine candidates cleared for clinical trial.

19 Apr, 2022 | 02:25h | UTC

Omicron-specific Sinopharm, Sinovac COVID vaccine candidates cleared for clinical trial – Reuters

 

Commentary on Twitter

 


M-A: Global prevalence of post COVID-19 condition or long COVID.

19 Apr, 2022 | 02:18h | UTC

Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review – The Journal of Infectious Diseases

Commentary: Global data reveal half may have long COVID 4 months on – CIDRAP

 

Commentary on Twitter (thread – click for more)

 


A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease.

19 Apr, 2022 | 02:14h | UTC

A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease – Open Forum Infectious Diseases

 

Commentary on Twitter

 


Review: Covid-19: virology, variants, and vaccines.

18 Apr, 2022 | 10:50h | UTC

Covid-19: virology, variants, and vaccines – BMJ Medicine

 

Commentary on Twitter

 


Household transmission of SARS-CoV-2 from unvaccinated asymptomatic and symptomatic household members with confirmed SARS-CoV-2 infection: an antibody-surveillance study.

18 Apr, 2022 | 10:52h | UTC

Household transmission of SARS-CoV-2 from unvaccinated asymptomatic and symptomatic household members with confirmed SARS-CoV-2 infection: an antibody-surveillance study – CMAJ Open

Commentary: COVID-19 household transmission is high, with children being a significant source of spread: study – CHEO

 

Commentary on Twitter (thread – click for more)

 


Analysis: Changing the assortment of available food and drink for leaner, greener diets.

18 Apr, 2022 | 10:39h | UTC

Changing the assortment of available food and drink for leaner, greener diets – The BMJ

News Release: Changing products on offer in shops and restaurants can lead to leaner, greener diets – BMJ

 


Incidence of electric scooter–associated injuries in Finland from 2019 to 2021.

18 Apr, 2022 | 09:54h | UTC

Incidence of Electric Scooter–Associated Injuries in Finland From 2019 to 2021 – JAMA Network Open

 

Commentary on Twitter

 


Systematic Review: The effect of conditional cash transfers on the control of neglected tropical disease.

18 Apr, 2022 | 09:38h | UTC

The effect of conditional cash transfers on the control of neglected tropical disease: a systematic review – The Lancet Global Health

Invited Commentary: The potential of conditional cash transfers for the control of neglected tropical diseases – The Lancet Global Health

Related: Does giving money to people, in low- and middle-income countries, without conditions attached lead to better health and other life improvements? – Cochrane Library

 

Commentary from the author on Twitter (thread – click for more)

 


A nationwide observational analysis in Israel showed a fourth dose of the Pfizer vaccine may reduce the short-term risk of Covid-19–related outcomes.

14 Apr, 2022 | 08:51h | UTC

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

Editorial: Covid-19 Boosters — Where from Here?

Related:

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines.

Observational study suggests a fourth dose of the Pfizer vaccine provided additional protection against severe disease in patients 60 years of age or older during the Omicron wave in Israel.

Perspective: The evidence on 4th doses of covid vaccines & the thorny question of age thresholds.

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

Covid-19: Fourth vaccine doses—who needs them and why?

[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

 

Commentary on Twitter

 


Study showed low rates of severe COVID-19 in children hospitalized with confirmed SARS-CoV-2 infection.

14 Apr, 2022 | 08:49h | UTC

Very low rates of severe COVID-19 in children hospitalised with confirmed SARS-CoV-2 infection in London, England – Journal of Infection

Commentary: Severe COVID-19 extremely rare among children – News Medical

Related:

[Preprint] Risk of Hospitalization, severe disease, and mortality due to COVID-19 in children with SARS-CoV-2 infection in Germany – “overall hospitalization rate associated with SARS-CoV-2 infection was 35.9 per 10,000 children, ICU admission rate was 1.7 per 10,000 and case fatality was 0.09 per 10,000”.

Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year – “In total, 99.995% of children and young people with a positive SARS-CoV-2 test survived”.

Editorial: COVID-19 vaccines for children – “Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis”.

COVID-19 disease severity in children infected with the Omicron variant.

Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year.

Study identifies risk factors for severe CoviD-19 in children.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

International study identifies predictors of severe outcomes in children with COVID-19.

 


Discharge preparation and readiness after birth: a scoping review of global policies, guidelines and literature.

14 Apr, 2022 | 08:07h | UTC

Discharge preparation and readiness after birth: a scoping review of global policies, guidelines and literature – BMC Pregnancy & Childbirth

Related:

WHO recommendations on maternal and newborn care for a positive postnatal experience.

Putting positive experiences at the center of postnatal care.

 


Economic evaluation: cost-effectiveness of installing barriers at bridge and cliff sites for suicide prevention in Australia.

14 Apr, 2022 | 08:01h | UTC

Cost-effectiveness of Installing Barriers at Bridge and Cliff Sites for Suicide Prevention in Australia – JAMA Network Open

Invited Commentary: Rethinking Suicide Prevention as a Public Health Issue – JAMA Network Open

 

Commentary on Twitter

 


Cohort Study: Mifepristone and misoprostol for undesired pregnancy of unknown location.

14 Apr, 2022 | 07:53h | UTC

Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location – Obstetrics & Gynecology

Commentary: Medication abortion pills safe for early use in patients even if ectopic pregnancy has not been ruled out – Brigham and Women’s Hospital

 


The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019.

13 Apr, 2022 | 11:03h | UTC

The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019 – The Lancet Regional Health Europe

Invited Commentary: The burden of young people’s mental health conditions in Europe: No cause for complacency – The Lancet Regional Health Europe

Related:

Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

New Global Burden of Disease analyses show depression and anxiety among the top causes of health burden worldwide, and a significant increase due to the COVID-19 pandemic.

 

Commentary on Twitter

(Article and images under a CC BY 4.0 license)

 


Perspective: The concept of classical herd immunity may not apply to COVID-19.

13 Apr, 2022 | 10:54h | UTC

The Concept of Classical Herd Immunity May Not Apply to COVID-19 – The Journal of Infectious Diseases

News Release: NIH experts discuss controlling COVID-19 in commentary on herd immunity – NIH News Releases

 

Commentary on Twitter

 


Drug resistant TB – latest developments in epidemiology, diagnostics and management.

13 Apr, 2022 | 10:09h | UTC

Drug resistant TB – latest developments in epidemiology, diagnostics and management – International Journal of Infectious Diseases

Related:

Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.

WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment

Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment

Canadian Tuberculosis Standards – 8th Edition.

Guideline: Treatment of Drug-Resistant Tuberculosis

NICE Guideline: Tuberculosis

The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis

Regimens to Treat Multidrug-resistant Tuberculosis: Past, Present and Future Perspectives

 


New WHO online course: Monkeypox epidemiology, preparedness and response.

13 Apr, 2022 | 10:03h | UTC

Monkeypox epidemiology, preparedness and response – OpenWHO

 

Commentary on Twitter

 


RCT: Single-dose HPV vaccination found effective among young African women.

12 Apr, 2022 | 10:08h | UTC

Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women – NEJM Evidence

News Releases:

Study boosts support for single-dose HPV vaccine regimen – University of Washington

One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer – World Health Organization

Related:

Three-year follow-up of 2-dose versus 3-dose HPV vaccine

 

Commentary on Twitter (thread – click for more)

 


More data suggests the Omicron variant causes milder disease compared to the Delta variant.

12 Apr, 2022 | 09:49h | UTC

Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study – The Lancet

Commentary: Covid-19: Symptomatic infection with omicron variant is milder and shorter than with delta, study reports – The BMJ

Related:

Another study suggests a lower risk of hospitalization and death from infection with SARS-CoV-2 Omicron variant vs. Delta.

Perspective: Challenges in inferring intrinsic severity of the SARS-CoV-2 Omicron variant.

Early assessment of the clinical severity of the SARS-CoV-2 omicron variant in South Africa.

Cohort Study: Incidence rates and clinical outcomes of SARS-CoV-2 infection with the Omicron and Delta variants in children younger than 5 years in the US.

[Preprint] SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters.

[Preprint] Study showed reduced clinical severity of Covid-19 patients admitted to hospitals in Gauteng, South Africa, during the Omicron-dominant fourth wave – “any combination of a less-virulent virus, comorbidities, high immunity from prior infection(s) or vaccination may be important contributors to this clinical presentation”.

Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.

Too early to tell, but preliminary information from doctors in South Africa suggests the new Covid variant Omicron may be associated with less severe disease.

 


Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis.

11 Apr, 2022 | 01:58h | UTC

Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis – The Lancet

Invited Commentary: How to interpret the total number of SARS-CoV-2 infections – The Lancet

 

Commentary on Twitter (thread – click for more)

 


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