Geriatrics | Page 9 of 57 | Links Medicus Content Curation & Alerts in Medicine

Underrepresentation of adults above age 75-80 years found in evaluation of new medications. 60-75 year-olds were reasonably well represented in clinical trials in proportion to the prevalence data in the US. #OAResearch https://t.co/2RL5fTo3LA

— JAMA Network Open (@JAMANetworkOpen) October 14, 2022

Review | Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease.

14 Oct, 2022 | 14:19h | UTC

Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology

Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology

Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis – Health Technology Assessment

Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports

Deprescribing in Palliative Cancer Care – Life

Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360

Process evaluation of implementation strategies to reduce potentially inappropriate medication prescribing in older population: A scoping review – Research in Social and Administrative Pharmacy

AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review – Gastroenterology

Development of a Metric to Detect and Decrease Low-Value Prescribing in Older Adults – JAMA Network Open

The MedSafer Study—Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial – JAMA Internal Medicine

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines – Supportive Care in Cancer

Prescribing practices, patterns, and potential harms in patients receiving palliative care: A systematic scoping review – Exploratory Research in Clinical and Social Pharmacy

A narrative review of evidence to guide deprescribing among older adults – Journal of General and Family Medicine

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens – The Lancet Health Longevity

Polypharmacy Management in Older Patients – Mayo Clinic Proceedings

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt international

Eliminating Medication Overload: A National Action Plan – Lown Institute

International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action – Drugs & Aging

Common ED Medication Errors: Polypharmacy – emDocs

Current and future perspectives on the management of polypharmacy – BMC Family Practice

Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety

Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international

Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety

Brief Review | Frailty in intensive care medicine must be measured, interpreted and taken into account!

12 Oct, 2022 | 13:51h | UTC

Frailty in intensive care medicine must be measured, interpreted and taken into account! – Intensive Care Medicine

Commentary on Twitter

Frailty should be evaluated in old #ICU pts to improve individual care & resource allocation! To-do list
? measure or estimate; use easy, validated/proven tools & be consistent
? interpret
⚖️ take into account (w other data) to support decision making
? https://t.co/J4qropYqon pic.twitter.com/NiBifBwmIm

— Intensive Care Medicine (@yourICM) October 7, 2022

Cohort Study | Migraine is linked to increased risk of subsequent Alzheimer’s and vascular dementia.

6 Oct, 2022 | 13:43h | UTC

Increased risk of all-cause, Alzheimer’s, and vascular dementia in adults with migraine in Korea: a population-based cohort study – The Journal of Headache and Pain

Commentary: Migraine May Increase Subsequent Dementia Risk – HealthDay

World guidelines for falls prevention and management for older adults: a global initiative.

5 Oct, 2022 | 13:58h | UTC

World guidelines for falls prevention and management for older adults: a global initiative – Age and Ageing

Review | Poor physical recovery after critical illness.

4 Oct, 2022 | 14:27h | UTC

Poor physical recovery after critical illness: incidence, features, risk factors, pathophysiology, and evidence-based therapies – Current Opinion in Critical Care

Cohort Study | Diabetes diagnosed at younger ages is associated with increased morbidity compared to diagnosis in older adults.

3 Oct, 2022 | 14:02h | UTC

Associations of Age at Diagnosis and Duration of Diabetes With Morbidity and Mortality Among Older Adults – JAMA Network Open

M-A | Carbon dioxide laser vs. vaginal estrogen for genitourinary syndrome of menopause.

29 Sep, 2022 | 13:24h | UTC

Comparison of Severity of Genitourinary Syndrome of Menopause Symptoms After Carbon Dioxide Laser vs Vaginal Estrogen Therapy: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary on Twitter

Vaginal laser and vaginal estrogen therapy showed similar improvement in genitourinary symptoms in this systematic review and meta-analysis of RCTs. #Research https://t.co/PpAf77CqKS

— JAMA Network Open (@JAMANetworkOpen) September 21, 2022

M-A of randomized trials | Regional anesthesia techniques and postoperative delirium.

28 Sep, 2022 | 13:48h | UTC

Regional anesthesia techniques and postoperative delirium: systematic review and meta-analysis – Minerva Anestesiologica

Effect of regional anesthesia on the postoperative delirium: A systematic review and meta-analysis of randomized controlled trials – Frontiers in Surgery

RCT: In older patients undergoing hip fracture surgery, regional anesthesia did not reduce the incidence of postoperative delirium compared to general anesthesia.

RCT | A comprehensive geriatric assessment may improve the quality of life in older people starting anticancer treatment.

27 Sep, 2022 | 13:16h | UTC

Integrated Geriatric Assessment and Treatment Effectiveness (INTEGERATE) in older people with cancer starting systemic anticancer treatment in Australia: a multicentre, open-label, randomised controlled trial – The Lancet Health Longevity

Invited Commentary: Integrating what matters to patients in the care of older adults with cancer – The Lancet Health Longevity

Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology – Journal of Clinical Oncology

What Every Oncologist Should Know About Geriatric Assessment for Older Patients With Cancer: Young International Society of Geriatric Oncology Position Paper – Journal of Clinical Oncology

Geriatric Assessment-Guided Care Processes for Older Adults: A Delphi Consensus of Geriatric Oncology Experts – Journal of the National Comprehensive Cancer Network

Cluster RCT: In older adults with advanced cancer, a geriatric assessment program reduced the toxic effects of cancer treatment.

Commentary from the author on Twitter

Excited that our #INTEGERATE Study RCT on the benefits of comprehensive geriatric assessment and integrated oncogeriatric care has been published. Thank you for your support! @easternhealthau @EHCSMonash @Prof_IanD @ParentePhillip #GeriOnc @LancetLongevity https://t.co/F0ikcg9hnK

— Kheng Soo (@KhengSoo1) August 22, 2022