Geriatrics
Global Burden of Alzheimer’s Disease and Other Dementias
30 Nov, 2018 | 02:43h | UTCInvited Commentary: Statistics on the burden of dementia: need for stronger data – The Lancet (free)
“In 2016, globally, 43·8 million individuals lived with dementia, increased from 20.2 million in 1990; dementia was the fifth leading cause of death globally (2·4 million) and more women than men had dementia” (via @TheLancet see Tweet with infographic)
Study: Trazodone Associated Risks
30 Nov, 2018 | 02:40h | UTCCommentaries: Study finds alternative to antipsychotic medication for seniors also has drawbacks – The Globe and Mail (free) AND Trazadone linked to more falls, major fractures in dementia patients – UPI (free) AND Trazadone associated with similar risk of falls and major fractures as antipsychotics in seniors with dementia – Canadian Medical Association Journal (free) AND Aggression in Dementia: Alternatives to Antipsychotics Also Have Side Effects – MedicalResearch.com (free)
NICE Guideline: Catheter-Associated Urinary Tract Infection
30 Nov, 2018 | 02:27h | UTCRelated: NICE Antimicrobial Prescribing Guidelines (free guidelines and resources)
Review: Antithrombotic Therapies for Elderly Patients
30 Nov, 2018 | 01:35h | UTC
Review: Non-Cystic Fibrosis Bronchiectasis in the Elderly
30 Nov, 2018 | 01:34h | UTC
Study: Cost-Effectiveness of an Optimized Intervention for Residents with Clinically Significant Agitation in Dementia
22 Nov, 2018 | 21:52h | UTCImproving the quality of life of care home residents with dementia: Cost-effectiveness of an optimized intervention for residents with clinically significant agitation in dementia – Alzheimer’s & Dementia (link to abstract – $ for full-text)
Commentaries: Care homes with dementia ‘carer champions’ reduce agitation and antipsychotics – carehome.co.uk (free) AND Improving dementia care and treatment saves thousands of pounds in care homes – University of Exeter (free)
Study: Prevalence of Falls in Older Adults with Self‐Reported Vision Impairment
20 Nov, 2018 | 15:41h | UTCCommentaries: Study: Impaired vision raises risk of falls in older adults – UPI (free) AND Having poor vision can raise risk for falls among older adults – American Geriatrics Society (free)
Study: Prevalence of Potentially Inappropriate Prescribing in Older People
20 Nov, 2018 | 15:27h | UTCEditorial: Tackling potentially inappropriate prescribing (free)
Commentary: Half of older patients exposed to potentially inappropriate prescribing – MedicalXpress (free)
Meta-Analysis: Antipsychotic Drug Use and Pneumonia
16 Nov, 2018 | 02:49h | UTCAntipsychotic drug use and pneumonia: Systematic review and meta-analysis – Journal of Psychopharmacology (link to abstract – $ for full-text)
Commentary: Antipsychotics May Increase Risk of Pneumonia, Meta-Analysis Suggests – Psychiatric News Alert (free)
“Although antipsychotic use was associated with a higher risk of pneumonia, the researchers stopped short of claiming causality, citing a lack of data from randomized, controlled trials and a failure of observational studies to control for relevant confounders like tobacco use and weight.” (from Psychiatric News Alert)
Randomized Trial: Effect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults
16 Nov, 2018 | 02:24h | UTCEffect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults: The D-PRESCRIBE Randomized Clinical Trial – JAMA (free for a limited period)
Video Summary: Effect of a Pharmacist-Led Intervention on Inappropriate Prescriptions in Older Adults (free)
Randomized Trial: Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization
16 Nov, 2018 | 02:21h | UTCEffect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentaries: A Novel Exercise Intervention and Functional Status in Very Elderly Patients During Acute Hospitalization – JAMA Internal Medicine (free for a limited period) AND Exercise intervention benefits elderly in hospital – OnMedica (free)
Author Interview: Effect of Exercise Intervention on Functional Decline in Very Elderly Patients (free audio)
Videos: Morning Exercise Session (free) AND Evening Exercise Session (free) AND Balance and Gait Retraining Exercises (free)
Study: Artificial Intelligence may Predict Alzheimer’s Years Before Diagnosis
9 Nov, 2018 | 02:50h | UTCA Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain – Radiology (free for a limited period)
Commentaries: Artificial intelligence predicts Alzheimer’s years before diagnosis – Radiology Society of North America (free) AND Expert reaction to study looking at AI technology, brain imaging and Alzheimer’s disease detection – Science Media Centre (free) AND AI May Detect Alzheimer’s Years Before Diagnosis – Medscape (free registration required)
Clinical Practice Guidelines for Quality Palliative Care
9 Nov, 2018 | 02:22h | UTCClinical Practice Guidelines for Quality Palliative Care, 4th Edition – National Consensus Project’s (free)
News Release: New National Guidelines Seek to Improve Access to Palliative Care for People Living with Serious Illness (free)
Commentaries: Palliative care guidelines updated with increased focus on collaboration, communication – ACP Internist (free) AND New Palliative Care Guidelines Demand ‘Seismic Shift’ in Care – Medscape (free registration required)
Meta-Analysis: Diagnostic Value of Symptoms and Signs for Identifying UTI in Older adults
9 Nov, 2018 | 02:05h | UTC“A number of symptoms and signs typically associated with UTI, such as nocturia, urgency and abnormal vital signs, were of limited use in older adult outpatients.”
Systematic Review: Supplements for Preventing Cognitive Decline in People with Mild Cognitive Impairment
9 Nov, 2018 | 01:59h | UTCVitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment – Cochrane Library (free)
“The evidence on vitamin and mineral supplements as treatments for MCI is very limited. “
Small Bowel Obstruction in the Elderly: A Plea for Comprehensive Acute Geriatric Care
9 Nov, 2018 | 01:47h | UTC
Deprescribing: The Fightback Against Polypharmacy Has Begun
5 Nov, 2018 | 12:11h | UTCDeprescribing: the fightback against polypharmacy has begun – The Pharmaceutical Journal (free) (via @Deprescribing)
Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject) AND Deprescribing recommendations: An essential consideration for clinical guideline developers – Research in Social and Administrative Pharmacy (free)
Gerontodermatology: The Fragility of the Epidermis in Older Adults
5 Nov, 2018 | 11:50h | UTC
Review: The Global Burden of Multiple Chronic Conditions
26 Oct, 2018 | 02:57h | UTCThe global burden of multiple chronic conditions: A narrative review – Preventive Medicine Reports (free)
Related: Multimorbidity: A Priority for Global Health Research (free report and commentaries) AND Meta-Analysis: Effectiveness of Interventions for Managing Multiple High-Burden Chronic Diseases in Older Adults (free study and commentaries) Designing a High-Performing Health Care System for Patients with Complex Needs (several perspectives on the subject)
Meta-Analysis: Efficacy, Effectiveness, and Safety of Herpes Zoster Vaccines
26 Oct, 2018 | 02:42h | UTC“Using the adjuvant recombinant subunit vaccine might prevent more cases of herpes zoster than using the live attenuated vaccine, but the adjuvant recombinant subunit vaccine also carries a greater risk of adverse events at injection sites.”
USPSTF Statement: Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults
26 Oct, 2018 | 02:28h | UTCEditorials: Challenges and Opportunities for Studying Routine Screening for Abuse (free) AND Addressing Intimate Partner Violence and Abuse of Older or Vulnerable Adults in the Health Care Setting—Beyond Screening (free)
Randomized Trial: Antipsychotics Ineffective for Delirium in Intensive Care Patients
26 Oct, 2018 | 02:01h | UTCHaloperidol and Ziprasidone for Treatment of Delirium in Critical Illness – New England Journal of Medicine (free for a limited period)
Editorial: Dopamine Antagonists in ICU Delirium (free for a limited period)
Commentaries: Common use of antipsychotics shown ineffective for delirium in intensive care patients – NIH News Releases (free) AND Antipsychotic Drugs Don’t Ease ICU Delirium Or Dementia – NPR (free) AND Antipsychotics ineffective for treating ICU delirium – Vanderbilt University Medical Center (free)
Related Research: Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium (free)
Want to Keep Your Brain Sharp? Take Care of Your Eyes And Ears
26 Oct, 2018 | 01:46h | UTCWant To Keep Your Brain Sharp? Take Care Of Your Eyes And Ears – NPR (free)
Related Articles: Longitudinal Relationship Between Hearing Aid Use and Cognitive Function in Older Americans – Journal of the American Geriatrics Society (free) AND Cataract surgery and age-related cognitive decline: A 13-year follow-up of the English Longitudinal Study of Ageing – NPR (free)
Report: Talking About Dying
26 Oct, 2018 | 01:39h | UTCNews Release: New report asks why doctors find it so hard to talk to patients about dying (free)
Commentaries: Doctors must talk ‘honestly’ to patients about dying – OnMedica (free) AND Doctors ‘need to start early conversation with patients about dying’ – BBC (free)
Sarcopenia: Consensus on Definition and Diagnosis
16 Oct, 2018 | 23:31h | UTCSarcopenia: revised European consensus on definition and diagnosis – Age and Ageing (free)