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Geriatrics

RCT | In patients with end-stage ankle osteoarthritis, total ankle replacement and arthrodesis resulted in comparable results.

16 Nov, 2022 | 13:45h | UTC

Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Trial shows benefits of two forms of ankle surgery for osteoarthritis – University College London

Summary for Patients: Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis

 


Editorial | Agitated patients in the intensive care unit: guidelines for causal rather than symptomatic treatment are warranted.

16 Nov, 2022 | 13:37h | UTC

Agitated Patients in the Intensive Care Unit: Guidelines for Causal Rather Than Symptomatic Treatment are Warranted – Journal of Intensive Care Medicine

 


RCT | Genicular nerve block offers short-term pain relief in patients with knee osteoarthritis.

15 Nov, 2022 | 12:50h | UTC

Genicular Nerve Block for Pain Management in Patients With Knee Osteoarthritis: A Randomized Placebo-Controlled Trial – Arthritis & Rheumatology

Commentary: Genicular nerve block may provide short-term pain relief for knee osteoarthritis – medwire News

 


M-A | Medication reviews and deprescribing as a single intervention in falls prevention.

11 Nov, 2022 | 12:53h | UTC

Medication reviews and deprescribing as a single intervention in falls prevention: a systematic review and meta-analysis – Age and Ageing

 


Associations between social connections and cognition: a global collaborative individual participant data meta-analysis.

10 Nov, 2022 | 13:44h | UTC

Associations between social connections and cognition: a global collaborative individual participant data meta-analysis – The Lancet Health Longevity

News Release: Living with others and community engagement are keys to reduced dementia risk – University of New South Wales

 

Commentary on Twitter (thread – click for more)

 


Review | Equal but different! Improving care for older LGBT+ adults.

10 Nov, 2022 | 13:39h | UTC

Equal but different! Improving care for older LGBT+ adults – Age and Ageing (free for a limited period)

 


Review | New horizons in the ageing autonomic nervous system: orthostatic hypotension and supine hypertension.

10 Nov, 2022 | 13:37h | UTC

New horizons in the ageing autonomic nervous system: orthostatic hypotension and supine hypertension – Age and Ageing

 


Complexities of care: common components of models of care in geriatrics.

9 Nov, 2022 | 12:22h | UTC

Complexities of care: Common components of models of care in geriatrics – Journal of the American Geriatrics Society

 


Cohort Study | Population-based estimates of 1-year mortality after major surgery among community-living older adults.

9 Nov, 2022 | 12:23h | UTC

Population-Based Estimates of 1-Year Mortality After Major Surgery Among Community-Living Older US Adults – JAMA Surgery (link to abstract – $ for full-text)

Commentaries:

One in Seven Older Adults Die Within a Year After Surgery – Medscape (free registration required)

Surgery Holds Danger for Seniors. Who’s Most at Risk? – HealthDay

 

Commentary on Twitter

 


Cohort Study | Association of hormone therapy with depression during menopause.

9 Nov, 2022 | 12:17h | UTC

Association of Hormone Therapy With Depression During Menopause in a Cohort of Danish Women – JAMA Network Open

Commentaries:

Expert reaction to study looking at HRT and depression during the menopause – Science Media Centre

Oral, Transdermal Hormone Therapy for Menopause Before Age 50 May Increase Risk of Depression – Psychiatric News Alert

 

Commentary on Twitter

 


Cohort Study | Fracture risk among older cancer survivors compared with older adults without a history of cancer.

4 Nov, 2022 | 13:33h | UTC

Fracture Risk Among Older Cancer Survivors Compared With Older Adults Without a History of Cancer – JAMA Oncology (free for a limited period)

Commentary: Frailty-Related Fracture Risk Higher for Seniors With Cancer History – HealthDay

 


RCT | Post-operative electrical muscle stimulation may attenuate loss of muscle mass after abdominal surgery in older adults.

4 Nov, 2022 | 13:19h | UTC

Post-operative electrical muscle stimulation attenuates loss of muscle mass and function following major abdominal surgery in older adults: a split body randomised control trial – Age and Ageing

 


USPSTF Statement | Hormone therapy is not recommended for the prevention of chronic conditions in postmenopausal women.

3 Nov, 2022 | 14:19h | UTC

Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: US Preventive Services Task Force Recommendation Statement – JAMA

Editorial: Menopausal Hormone Therapy for Prevention of Chronic Conditions: When Is Enough, Enough? – JAMA

Evidence Report: Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

JAMA Patient Page: Menopausal Hormone Therapy for Prevention of Chronic Conditions

Author Interview: USPSTF Recommendation: Hormone Therapy for Prevention of Postmenopausal Chronic Conditions – JAMA

Commentary: USPSTF: Hormone Therapy Not Advised for Primary Prevention of Chronic Conditions – HealthDay 

 


Observational study suggests Apixaban for AF is associated with a lower risk of GI bleeding vs. other DOACs.

3 Nov, 2022 | 13:32h | UTC

Comparative Effectiveness and Safety Between Apixaban, Dabigatran, Edoxaban, and Rivaroxaban Among Patients With Atrial Fibrillation: A Multinational Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Best blood thinner for minimizing bleeding risk identified – University College London

Commentary: GI Bleeding Lower With Apixaban Versus Other DOACs in A-Fib – HealthDay

 


Sarcopenia definition, diagnosis and treatment: consensus is growing.

1 Nov, 2022 | 12:01h | UTC

Sarcopenia definition, diagnosis and treatment: consensus is growing – Age and Ageing

Related:

Singapore Clinical Practice Guidelines For Sarcopenia: Screening, Diagnosis, Management and Prevention – The Journal of Frailty & Aging

Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management – The journal of nutrition, health & aging

Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report – Age and Ageing

 


Brief Review | Preventing pressure injuries among patients in the intensive care unit.

1 Nov, 2022 | 11:50h | UTC

Preventing pressure injuries among patients in the intensive care unit: insights gained – Intensive Care Medicine

 

Commentary on Twitter

 


ACC Expert consensus for integrating atherosclerotic cardiovascular disease and multimorbidity treatment.

31 Oct, 2022 | 13:59h | UTC

2022 ACC Expert Consensus Decision Pathway for Integrating Atherosclerotic Cardiovascular Disease and Multimorbidity Treatment: A Framework for Pragmatic, Patient-Centered Care: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Commentary: American College of Cardiology shares expert analysis on treating ASCVD patients with multiple chronic conditions – Cardiovascular Business

 

Commentary on Twitter

 


Dose-reduced direct oral anticoagulants: practical considerations.

31 Oct, 2022 | 13:52h | UTC

Peripheral Matters | Dose-Reduced Direct Oral Anticoagulants: Practical Considerations – American College of Cardiology

 


Study | No benefit from frailty screening over a geriatric-assessment-for-all approach in older patients with cancer.

31 Oct, 2022 | 13:40h | UTC

A Two-Step Frailty Assessment Strategy in Older Patients With Solid Tumors: A Decision Curve Analysis – Journal of Clinical Oncology

 


Optimizing medication use in older adults with rheumatic diseases: deprescribing as an approach when less may be more.

26 Oct, 2022 | 14:33h | UTC

Optimizing Medication Use in Older Adults With Rheumatic Musculoskeletal Diseases: Deprescribing as an Approach When Less May Be More – ACP Open Rheumatology

Related:

Facing the challenge of polypharmacy when prescribing for older people with cardiovascular disease. A review by the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy – European Heart Journal – Cardiovascular Pharmacotherapy

Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology

Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology

Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis – Health Technology Assessment

Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports

How-to guide for medication reviews in older adults with cancer: A Young International Society of Geriatric Oncology and Nursing & Allied Health Interest Group initiative – Journal of Geriatric Oncology

Deprescribing in Palliative Cancer Care – Life

Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360

Process evaluation of implementation strategies to reduce potentially inappropriate medication prescribing in older population: A scoping review – Research in Social and Administrative Pharmacy

AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review – Gastroenterology

Development of a Metric to Detect and Decrease Low-Value Prescribing in Older Adults – JAMA Network Open

The MedSafer Study—Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial – JAMA Internal Medicine

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines – Supportive Care in Cancer

Prescribing practices, patterns, and potential harms in patients receiving palliative care: A systematic scoping review – Exploratory Research in Clinical and Social Pharmacy

A narrative review of evidence to guide deprescribing among older adults – Journal of General and Family Medicine

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens – The Lancet Health Longevity

Polypharmacy Management in Older Patients – Mayo Clinic Proceedings

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt international

Eliminating Medication Overload: A National Action Plan – Lown Institute

International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action – Drugs & Aging

Common ED Medication Errors: Polypharmacy – emDocs

Current and future perspectives on the management of polypharmacy – BMC Family Practice

Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety

Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international

Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety

 


New horizons in Type 2 myocardial infarction: pathogenesis, assessment and management of an emerging geriatric disease.

26 Oct, 2022 | 14:27h | UTC

New horizons in Type 2 myocardial infarction: pathogenesis, assessment and management of an emerging geriatric disease – Age and Ageing

 


M-A | Non-pharmacologic and pharmacologic treatments for anxiety in long-term care.

26 Oct, 2022 | 14:26h | UTC

Non-pharmacologic and pharmacologic treatments for anxiety in long-term care: a systematic review and meta-analysis – Age and Ageing

 


Systematic Review | Comprehensive geriatric assessment in perioperative care.

24 Oct, 2022 | 14:07h | UTC

Comprehensive geriatric assessment (CGA) in perioperative care: a systematic review of a complex intervention – BMJ Open

 


Systematic Review | Antidepressants for hip and knee osteoarthritis.

24 Oct, 2022 | 14:04h | UTC

Antidepressants for hip and knee osteoarthritis – Cochrane Library

 


Cohort Study | Association of hyperopia with incident clinically significant depression.

20 Oct, 2022 | 12:18h | UTC

Association of hyperopia with incident clinically significant depression: epidemiological and genetic evidence in the middle-aged and older population – British Journal of Ophthalmology

Commentary: Older Individuals with Hyperopia More Likely to Develop Incident Depression – HCP Live

 


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