General Interest
India’s COVID-19 crisis: a call for international action.
17 May, 2021 | 08:43h | UTCIndia’s COVID-19 crisis: a call for international action – The Lancet
Commentary on Twitter (thread – click for more)
The team @IndiaCOVIDSOS and others call for international action for India’s COVID-19 crisis in their Lancet paper.https://t.co/T7RvexuMJP@paimadhu @PrakashLab @KrutikaKuppalli @BhramarBioStat @spkalantri @cspramesh pic.twitter.com/QkuYv2QEb6
— Raj Kumar Manna (@rajphys) May 14, 2021
#ACC21 – RCT: No significant differences in cardiovascular events or major bleeding between patients receiving 81 mg vs. 325 mg of aspirin daily.
17 May, 2021 | 08:31h | UTCComparative Effectiveness of Aspirin Dosing in Cardiovascular Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: High- and Low-Dose Aspirin Equivalent in ASCVD: ADAPTABLE – TCTMD AND Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness – ADAPTABLE – American College of Cardiology
Video: Aspirin Dosing: A Patient-centric Trial Assessing Benefits And Long-term Effectiveness Trial
WHO: Wealthy nations urged to delay youth Covid vaccines, donate to solidarity scheme
17 May, 2021 | 08:40h | UTCCommentaries: Vaccinate vulnerable global poor before children in rich countries, WHO says – The Guardian AND Covid: Delay child vaccinations and share jabs with Covax, says WHO – BBC
Report: Implementing high-quality primary care – “pay for primary care teams to care for people, not physicians to deliver services”.
17 May, 2021 | 08:11h | UTCOriginal report: Implementing High-Quality Primary Care: Rebuilding the Foundation of Health Care – National Academies of Sciences, Engineering, and Medicine
Cohort study of 12,306 pediatric COVID-19 patients finds only 16.5% presented with typical respiratory symptoms (cough, dyspnea). 13.9% had GI symptoms, 8.1% had dermatological symptoms (rash), 4.8% had neurological (headache), and 18.8% had other non-specific symptoms (fever, malaise, myalgia, arthralgia and disturbances of smell or taste).
14 May, 2021 | 08:48h | UTCCommentary: COVID-19: Majority of infected children may not show typical symptoms – Nature Publishing Group
Commentary on Twitter
A retrospective cohort study of 12,306 pediatric COVID-19 patients
📍5% require hospitalization
📍18% of these require critical care
📍4% of these require ventilation
https://t.co/X6MTdS8D1i— RJ MacDonald MD 🚴♂️🏄🏻🎾 (@Kidsdoc1Rick) May 13, 2021
Perspective | The Covid-19 Infodemic — Applying the Epidemiologic Model to Counter Misinformation.
14 May, 2021 | 08:44h | UTCCommentary: Treating the COVID-19 ‘infodemic’ as an epidemic – University of Pennsylvania
RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.
14 May, 2021 | 08:46h | UTCHeterologous prime-boost COVID-19 vaccination: initial reactogenicity data – The Lancet
Commentaries: More side effects noted after using 2 different COVID vaccines – CIDRAP AND Covid vaccines: Mixing increases reports of mild side-effects – BBC
Perspective | Vaccines seem to work well against coronavirus variants. It’s also complicated.
14 May, 2021 | 08:41h | UTCVaccines seem to work well against coronavirus variants. It’s also complicated – STAT
CDC says fully vaccinated Americans can go indoors and outdoors without masks.
14 May, 2021 | 08:38h | UTCCDC Guidance: Interim Public Health Recommendations for Fully Vaccinated People – Centers for Disease Control and Prevention
Commentaries: CDC backtracks, saying fully vaccinated people can go maskless indoors – STAT AND Fully Vaccinated People Can Stop Wearing Masks Indoors And Outdoors, CDC Says – NPR AND CDC: No masks needed for COVID-vaccinated Americans – CIDRAP
Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”.
14 May, 2021 | 08:39h | UTCVaccinating children against SARS-CoV-2 – The BMJ
Related: Pfizer COVID-19 shot expanded to US children as young as 12.
Large trial with over 200.000 patients finds ovarian cancer screening does not reduce deaths.
14 May, 2021 | 08:32h | UTCCommentaries: Screening for ovarian cancer did not reduce early deaths – Imperial College London AND Annual screening for ovarian cancer does not save lives, study finds – The Guardian
Opinion | Let’s banish the term ‘patient’ from the health care lexicon.
14 May, 2021 | 08:19h | UTCLet’s banish the term ‘patient’ from the health care lexicon – STAT
Report | COVID-19: Make it the Last Pandemic
13 May, 2021 | 06:09h | UTCCOVID-19: Make it the Last Pandemic – Independent Panel for Pandemic Preparedness and Response
Commentaries: Report of the Independent Panel for Pandemic Preparedness and Response: making COVID-19 the last pandemic – The Lancet AND WHO ‘needs more powers’ says independent panel co-chair Helen Clark – Devex AND COVID-19 Was ‘A Preventable Disaster,’ WHO-Ordered Report Says – NPR AND How the world failed to curb COVID – Nature AND Panel suggests WHO should have more power to stop pandemics – Associated Press AND ‘A toxic cocktail:’ Panel delivers harsh verdict on the world’s failure to prepare for pandemic – Science AND Covid: Serious failures in WHO and global response, report finds – BBC AND Covid pandemic should serve as ‘Chernobyl moment’ for global health reform, international experts say – STAT
Commentary on Twitter
For the past 8 months, @TheIndPanel has been examining the state of #pandemic preparedness and responses to #COVID19. In a new report, they describe 13 key events that shaped its course, and outline recommendations to make this the #LastPandemic. Read https://t.co/KrcBTFEZ3J. pic.twitter.com/exH80QZ9Xl
— The Lancet (@TheLancet) May 12, 2021
[Not published yet] Observational study in Indonesia finds China’s Sinovac COVID-19 vaccine (CoronaVac) was 98% effective at preventing death and 96% effective at preventing hospitalization in healthcare workers
13 May, 2021 | 06:07h | UTCIndonesia study finds China’s Sinovac COVID-19 vaccine effective in medical staff – Reuters
Perspective | How covid-19 revealed the scandal of medical oxygen supplies worldwide
13 May, 2021 | 06:02h | UTCHow covid-19 revealed the scandal of medical oxygen supplies worldwide – Nature
Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”.
13 May, 2021 | 06:04h | UTCAmerican Kids Can Wait – The Atlantic
Commentary on Twitter
Now in the Atlantic, @TracyBethHoeg @MonicaGandhi9 and I argue that we ought to vaccinate OLDER people around the globe before we vaccinate children in high income nations. It is in OUR best interest to do sohttps://t.co/B0O8xj4fo1
— Vinay Prasad MD MPH (@VPrasadMDMPH) May 12, 2021
RCT: Tympanostomy-tube placement does not reduce episodes of acute otitis media among children 6 to 35 months of age with recurrent acute otitis media
13 May, 2021 | 05:57h | UTCCommentary: No lasting benefit to tubes over antibiotics for childhood ear infections – University of Pittsburgh
Study: More nurses lead to fewer patient deaths & readmissions, shorter hospital stays, and savings
13 May, 2021 | 05:55h | UTCNews release: More nurses lead to fewer patient deaths & readmissions, shorter hospital stays, and savings – The Lancet
Original study: Effects of nurse-to-patient ratio legislation on nurse staffing and patient mortality, readmissions, and length of stay: a prospective study in a panel of hospitals (free registration required)
Commentary on Twitter
NEW—More nurses lead to fewer patient deaths and readmissions, shorter hospital stays, and cost-savings for hospitals, suggests study of recent Australian state policy to introduce a minimum ratio of one nurse to four patients for day shifts. Read https://t.co/zTZNt8viPU. pic.twitter.com/B812I0P6N2
— The Lancet (@TheLancet) May 12, 2021
Perspective | How COVID broke the evidence pipeline
13 May, 2021 | 06:01h | UTCHow COVID broke the evidence pipeline – Nature
Editorial: Evidence-based medicine: how COVID can drive positive change – Nature
Related: Scientists say the rush to do Covid research led to a whole lot of waste
Commentary on Twitter
The weak pursuit of evidence-based medicine during the pandemic.
Thankfully, the #RECOVERY and #SOLIDARITY collaborative trial groups led the way in rapidly accumulating pivotal data asking the right questions with large sample size https://t.co/aSAhQvq5dz @hcpearson @nature pic.twitter.com/iM956krq0Q— Eric Topol (@EricTopol) May 12, 2021
Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).
12 May, 2021 | 08:55h | UTC
Pfizer COVID-19 shot expanded to US children as young as 12.
12 May, 2021 | 08:53h | UTCPfizer COVID-19 shot expanded to US children as young as 12 – Associated Press
Counterpoint: Covid vaccines for children should not get emergency use authorization – The BMJ Opinion
Commentaries: Covid-19: FDA authorises Pfizer vaccine for children 12-15 – The BMJ AND Expert reaction to U.S. FDA authorising Pfizer-BioNTech COVID-19 vaccine for emergency use in adolescents – Science Media Centre
Population-based cohort study: Non-hospitalized COVID-19 patients have low-risk of serious long-term effects, but visits to general practitioners and outpatient hospital visits are increased.
12 May, 2021 | 08:47h | UTCCommentaries: Non-hospitalized COVID-19 patients: Low-risk of serious long-term effects, but more visits to doctor – The Lancet AND Any COVID-19 Infection Raises Odds for Lingering Symptoms, Study Finds – HealthDay AND Those with mild COVID-19 seek more primary care than uninfected peers – CIDRAP
Coronavirus variants are spreading in India — what scientists know so far.
12 May, 2021 | 08:44h | UTCCoronavirus variants are spreading in India — what scientists know so far – Nature
COVID-19 oxygen needs in low- and middle-income countries have tripled in just three months – where are solutions?
12 May, 2021 | 08:43h | UTC
Ten simple steps to improve ventilation in healthcare facilities
11 May, 2021 | 09:27h | UTCTen simple steps to improve ventilation in healthcare facilities – Essential Critical Care
Commentary on Twitter
I've written ten simple steps to improve ventilation in healthcare facilities… with no jargon and loads of photos.
With expert input from @akm5376 @vfmcneill & @kartc from @IndiaCOVIDSOS.
Download here: https://t.co/OzsDXfPavm#COVIDisAirborne pic.twitter.com/UtsRO0IgWr
— Bex Sierra (@Global_ICU) May 5, 2021