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General Interest

‘We suppressed our scientific imagination’: four experts examine the big successes and failures of the COVID response so far.

15 Mar, 2022 | 08:47h | UTC

‘We suppressed our scientific imagination’: four experts examine the big successes and failures of the COVID response so far – The Conversation

 

Case Report: “Popeye deformity” associated with proximal biceps tendon rupture.

15 Mar, 2022 | 08:25h | UTC

“Popeye deformity” associated with proximal biceps tendon rupture – Canadian Medical Association Journal

 

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.

14 Mar, 2022 | 01:31h | UTC

Long-Term Cannabis Use and Cognitive Reserves and Hippocampal Volume in Midlife – The American Journal of Psychiatry (link to abstract – $ for full-text)

Commentary: Long-Term Cannabis Use Associated With Cognitive Deficits in Midlife – Psychiatric News Alert

 

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21.

11 Mar, 2022 | 10:16h | UTC

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21 – The Lancet

News Release: Global death toll of COVID-19 pandemic may be more than three times higher than official records, estimates of excess deaths indicate – The Lancet

Commentaries:

COVID’s true death toll: far higher than official records – Nature

Covid deaths probably three times higher than records say – BBC

Related:

Editorial: “Excess deaths” is the best metric for tracking the pandemic.

The pandemic’s true death toll: millions more than official counts.

We can be confident there have been far more than 5 million global Covid deaths – “Estimating ‘excess’ fatalities, a more robust analysis method, puts the pandemic’s grim toll between 10m and 19m people”.

Global Covid-19 deaths surpass five million.

Effects of the Covid-19 pandemic on life expectancy and premature mortality in 2020 – this time series analysis showed there were more than 28 million excess years of life lost in 2020 in 31 countries.

Under-reporting of deaths limits our understanding of true burden of covid-19.

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

 

Commentary on Twitter

https://twitter.com/EricTopol/status/1502064507597860872

 

COVID pandemic 2nd anniversary: 3 things we got wrong, and 3 things to watch out for.

11 Mar, 2022 | 10:07h | UTC

COVID pandemic 2nd anniversary: 3 things we got wrong, and 3 things to watch out for – The Conversation

 

Misinformation: susceptibility, spread, and interventions to immunize the public.

11 Mar, 2022 | 10:03h | UTC

Misinformation: susceptibility, spread, and interventions to immunize the public – Nature Medicine

See also: An epidemic of uncertainty: rumors, conspiracy theories and vaccine hesitancy – Nature Medicine

 

Report: Measuring sex, gender identity, and sexual orientation.

11 Mar, 2022 | 09:55h | UTC

Report: Measuring Sex, Gender Identity, and Sexual Orientation – National Academies of Sciences, Engineering, and Medicine

News Release: NIH Should Standardize Questions Used to Collect Sex, Gender, and Sexual Orientation Data in Studies and Surveys, Says New Report – National Academies of Sciences, Engineering, and Medicine

Commentary: NIH-funded study offers recommendations for measuring gender, sexual orientation – Healthcare IT News

 

Perspective: What do we know about Covid’s impact on the brain?

10 Mar, 2022 | 10:46h | UTC

What do we know about Covid’s impact on the brain? – The Guardian

Related: SARS-CoV-2 is associated with changes in brain structure in UK Biobank.

 

Perspective: The time toxicity of cancer treatment.

10 Mar, 2022 | 10:15h | UTC

The Time Toxicity of Cancer Treatment – Journal of Clinical Oncology

 

WHO says COVID boosters needed, reversing previous call.

9 Mar, 2022 | 09:49h | UTC

WHO says COVID boosters needed, reversing previous call – Associated Press

 

Commentary on Twitter

 

Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices.

9 Mar, 2022 | 08:45h | UTC

Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices – BMJ Open

 

How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain.

8 Mar, 2022 | 08:56h | UTC

How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain – The Conversation

 

The next variant: three key questions about what’s after Omicron.

8 Mar, 2022 | 08:54h | UTC

The next variant: three key questions about what’s after Omicron – Nature

 

Nature is trialling transparent peer review — the early results are encouraging.

8 Mar, 2022 | 08:52h | UTC

Nature is trialling transparent peer review — the early results are encouraging – Nature

 

COVID-19: How Omicron overtook Delta in three charts.

7 Mar, 2022 | 00:46h | UTC

COVID-19: How Omicron overtook Delta in three charts – Nature

 

Viewpoint | Looking back on the history of patient safety: an opportunity to reflect and ponder future challenges.

6 Mar, 2022 | 23:51h | UTC

Looking back on the history of patient safety: an opportunity to reflect and ponder future challenges – BMJ Quality & Safety

 

Quantifying the effects of the COVID-19 pandemic on gender equality on health, social, and economic indicators.

4 Mar, 2022 | 10:04h | UTC

Quantifying the effects of the COVID-19 pandemic on gender equality on health, social, and economic indicators: a comprehensive review of data from March, 2020, to September, 2021 – The Lancet

Commentaries:

Gender equality and COVID-19: act now before it is too late – The Lancet

Social and economic effects of the COVID-19 pandemic threaten to reverse progress towards gender equality: study – The Lancet

 

Commentary on Twitter (thread – click for more)

 

Viewpoint: Understanding and communicating uncertainty in achieving diagnostic excellence.

4 Mar, 2022 | 09:56h | UTC

Understanding and Communicating Uncertainty in Achieving Diagnostic Excellence – JAMA (free for a limited period)

 

Cohort Study: Association between screen time exposure in children at 1 year of age and autism spectrum disorder at 3 years of age.

4 Mar, 2022 | 09:54h | UTC

Association Between Screen Time Exposure in Children at 1 Year of Age and Autism Spectrum Disorder at 3 Years of Age: The Japan Environment and Children’s Study – JAMA Pediatrics

Commentary: Screen Time Linked to Autism Spectrum Disorder in Boys – HealthDay

Related:

M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.

Media and Young Minds – American Academy of Pediatrics

Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.

 

M-A: Effects of media stories of hope and recovery on suicidal ideation and help-seeking attitudes and intentions.

4 Mar, 2022 | 08:35h | UTC

Effects of media stories of hope and recovery on suicidal ideation and help-seeking attitudes and intentions: systematic review and meta-analysis – The Lancet Public Health

 

WHO: COVID-19 pandemic triggers a 25% increase in the prevalence of anxiety and depression worldwide.

3 Mar, 2022 | 09:44h | UTC

News Release: COVID-19 pandemic triggers 25% increase in prevalence of anxiety and depression worldwide – World Health Organization

Scientific Brief: Mental health and COVID-19: Early evidence of the pandemic’s impact – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

National, regional, and global causes of mortality in 5–19-year-olds from 2000 to 2019: a systematic analysis.

3 Mar, 2022 | 08:51h | UTC

National, regional, and global causes of mortality in 5–19-year-olds from 2000 to 2019: a systematic analysis – The Lancet Global Health

Invited commentary: Child and adolescent deaths: a call for strengthening mortality surveillance systems – The Lancet Global Health

 

Wuhan market was epicenter of pandemic’s start, studies suggest.

2 Mar, 2022 | 08:59h | UTC

Wuhan market was epicentre of pandemic’s start, studies suggest – Nature

Related:

[Preprint] SARS-like viruses may jump from animals to people hundreds of thousands of times a year.

Did the coronavirus jump from animals to people twice? – Nature

The Origins of SARS-CoV-2: A Critical Review.

The animal origin of SARS-CoV-2 – “Trading of animals susceptible to bat coronaviruses is the likely cause of the COVID-19 pandemic”.

Fauci says natural origins theory of coronavirus is still the most likely.

 

Commentary on Twitter

 

[Preprint] Study shows significantly reduced effectiveness of the Pfizer vaccine in children 5 to 11 after the emergency of the Omicron variant.

1 Mar, 2022 | 08:54h | UTC

Effectiveness of the BNT162b2 vaccine among children 5-11 and 12-17 years in New York after the Emergence of the Omicron Variant – medRxiv

Commentaries:

Pfizer Covid vaccine is less effective in kids 5 to 11, study finds – STAT

Pfizer Covid-19 vaccine effectiveness fell quickly for kids during Omicron surge but still offered some protection against severe disease – CNN

More mask mandates fall as poor COVID vaccine protection noted in young kids – CIDRAP

 

RCT: A mindfulness-oriented intervention may reduce opioid misuse and chronic pain in primary care.

1 Mar, 2022 | 08:32h | UTC

Mindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Mindfulness-Based Intervention Found to Reduce Chronic Pain and Opioid Misuse – Psychiatric News Alert

 

Commentary on Twitter

 

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