Gastroenterology (all articles)
Proof-of-concept Trial: Fecal Microbiota Transplantation for Primary Clostridium difficile Infection
7 Jun, 2018 | 02:50h | UTCCommentary: Antibiotics Weren’t Used to Cure These Patients. Fecal Bacteria Were – The New York Times (10 articles per month are free) AND The Latest Poop On Fecal Transplants Vs. Antibiotics For C. Difficile Diarrhea – Forbes (free)
ASCO 2018: Improved Overall Survival with Adjuvant mFOLFIRINOX in Resected Pancreatic Cancer
7 Jun, 2018 | 02:38h | UTCAdjuvant mFOLFIRINOX vs Gemcitabine in Resected Pancreatic Cancer – The ASCO Post (free)
Related: Pancreatic Cancer Survival Jumps With Postsurgical Chemo Combo – OncLive (free) AND Study Finds Rare Gain for Tough-To-Treat Pancreatic Cancer – Associated Press (free)
Canadian Guideline: Management of Chronic Hepatitis C
7 Jun, 2018 | 02:36h | UTCCommentaries: Hepatitis C guideline recommends screening for all people born 1945-1975 – CMAJ, via EurekAlert (free) AND Canadian Group Offers New Guidelines on Hepatitis C Screening, Management – NEJM Physician’s First Watch (free)
Related Guidelines: HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C – American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) (free) AND EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
Research: Rates of Infection after Colonoscopy and Endoscopy Higher Than Expected
6 Jun, 2018 | 21:48h | UTCRates of infection after colonoscopy and osophagogastroduodenoscopy in ambulatory surgery centres in the USA – Gut (link to abstract – $ for full-text)
Commentary: Infection Rates After Colonoscopy, Endoscopy at US Specialty Centers Are Far Higher Than Previously Thought – Johns Hopkins Medicine, via NewsWise (free)
Opinion: Rush to Treat Non-alcoholic Fatty Liver Disease Causing More Harm than Good
6 Jun, 2018 | 21:45h | UTCRush to treat liver patients causing more harm than good – The University of Leeds (free) (via @PaulGlasziou)
Original article: Too much medicine: overdiagnosis and overtreatment of non-alcoholic fatty liver disease- The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Guideline: Colorectal Cancer Screening for Average‐risk Adults
1 Jun, 2018 | 03:45h | UTCNews Release: American Cancer Society Updates Colorectal Cancer Screening Guideline (free)
Commentaries: American Cancer Society recommends earlier colorectal cancer screening – Reuters (free) AND American Cancer Society advises colorectal screens at 45, not 50 – UPI (free) AND Cancer Group Calls for Colorectal Cancer Screening Starting at Age 45 – The New York Times (10 articles per month are free) AND Get Screened Earlier For Colorectal Cancer, Urges American Cancer Society – NPR (free)
Related Guidelines (all suggest screening should begin at age 50 years in average-risk individuals): Colorectal Cancer Screening – U.S. Preventive Services Task Force (free resources) AND Recommendations on screening for colorectal cancer in primary care – Canadian Task Force on Preventive Health Care (free) AND Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer – The American Journal of Gastroenterology (free)
ESMO Guideline: Gastrointestinal Stromal Tumors
1 Jun, 2018 | 03:13h | UTC
Meta-Analysis: Pharmacological Therapies for the Treatment of Opioid-induced Constipation
29 May, 2018 | 17:50h | UTCEfficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis – Gut (link to abstract – $ for full-text)
Commentary: Naloxone, naldemedine appear best for opioid-induced constipation after laxatives – ACP Gastroenterology (free)
IDSA & AASLD Hepatitis C Guidance Updates
28 May, 2018 | 12:56h | UTCNews Release: HCV Guidance Updates Recommendations for Screening and Treating Key Populations (free)
Related Guideline: EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
ASCO Guideline: Metastatic Pancreatic Cancer
24 May, 2018 | 23:18h | UTCMetastatic Pancreatic Cancer: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)
Related Guideline: Pancreatic cancer in adults: diagnosis and management – National Institute for Health and Care Excellence (free)
Related Systematic Review: Chemotherapy and radiotherapy for advanced pancreatic cancer – Cochrane Library (free)
Cohort Study: Inflammatory Bowel Disease Patients Have Higher Risk of Parkinson’s disease
24 May, 2018 | 22:37h | UTCCommentary: Inflammatory bowel disease may raise Parkinson’s risk – Medical News Today (free)
Review: Managing Portal Hypertension in Patients with Liver Cirrhosis
24 May, 2018 | 22:40h | UTCManaging portal hypertension in patients with liver cirrhosis – F1000 Research (free)
Cohort Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence
16 May, 2018 | 01:13h | UTCAssociation of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA (free for a limited period)
Related Review: Optimizing post‐polypectomy surveillance: A practical guide for the endoscopist – Digestive Endoscopy (free) AND Optimal Colonoscopy Surveillance Interval after Polypectomy – Clinical Endoscopy (free)
Related Guidelines: Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer (free) AND Korean Guidelines for Postpolypectomy Colonoscopy Surveillance – Digestive Endoscopy (free) AND Colorectal cancer surveillance after index colonoscopy: Guidance from the Canadian Association of Gastroenterology (free) AND Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline (free)
Advanced adenomas seem to be associated with subsequent increased risk for colorectal cancer, but nonadvanced adenomas may not be associated with increased risk.
Guideline: Screening, Prevention and Management of Hepatitis B and C in Sexual Health Settings
4 May, 2018 | 02:05h | UTC
Cohort Study: Incidence, Prevalence and 5-year Pancreatic-related Mortality of Pancreatic Cysts
3 May, 2018 | 20:31h | UTCCommentary: Incidental Pancreatic Cysts: Majority Don’t Progress to Cancer – Medscape (free registration required)
Guideline: Non-variceal Upper Gastrointestinal Bleeding
3 May, 2018 | 20:34h | UTCSource: Critical Care Reviews Newsletter
Randomized Controlled Trial: Effects of Omitting Antibiotics in Uncomplicated Acute Diverticulitis
3 May, 2018 | 20:27h | UTCLong-Term Effects of Omitting Antibiotics in Uncomplicated Acute Diverticulitis – American Journal of Gastroenterology (link to abstract – $ for full-text)
Commentary: Uncomplicated acute diverticulitis: omitting antibiotics found safe in DIABOLO – Univadis (free registration required)
Review: Surgery for Metastatic GISTs
3 May, 2018 | 19:20h | UTC
Meta-Analysis: Probiotics for the Prevention of Clostridium difficile
27 Apr, 2018 | 02:36h | UTCCommentary: Probiotics may be safe, low-cost prevention tool for Clostridium difficile infections – News Medical (free)
Related Articles: The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use – Cochrane Library (free) AND Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis – Antibiotics (free) AND Timely Use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection: A Systematic Review With Meta-Regression Analysis – Gastroenterology (free)
Randomized Trial: Sigmoidoscopy Screening and Colorectal Cancer Incidence and Mortality in Women and Men
25 Apr, 2018 | 13:36h | UTCLong-Term Effectiveness of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality in Women and Men: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Sigmoidoscopy reduces colon cancer risk for men, but not women – American College of Physicians, via MedicalXpress (free) AND Sigmoidoscopy reduces colon cancer risk for men, but not women – 2 Minute Medicine (free)
Cohort Study: Proton‐Pump Inhibitors and Risk of Pneumonia in Older Adults
24 Apr, 2018 | 19:29h | UTCCommentary: Commonly prescribed heartburn drug linked to Pneumonia in Older Adults – University of Exeter (free)
Related: Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free) AND Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)
Source: Hospital Medicine Virtual Journal Club
Pancreatitis: Pearls & Pitfalls
23 Apr, 2018 | 20:59h | UTCPancreatitis: Pearls & Pitfalls – emDocs (free)
Related guidelines: American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis – Gastroenterology (free) AND Clinical practice guideline: management of acute pancreatitis – Canadian Journal of Surgery (free)
Review: Management of Barrett’s Esophagus with Low-grade Dysplasia
23 Apr, 2018 | 20:47h | UTCManagement of Barrett’s esophagus with low-grade dysplasia – Diseases of the Esophagus (free)
Randomized Trial of Normothermic Preservation in Liver Transplantation
20 Apr, 2018 | 01:56h | UTCA randomized trial of normothermic preservation in liver transplantation – Nature (free PDF for a limited period)
Commentaries: Room temperature liver storage technique improves transplant success – University of Oxford (free) AND Keeping livers ‘alive’ boosts transplant success, trial finds – BBC (free) AND A ‘breakthrough in organ preservation’: Study shows keeping livers warm helps preserve them for transplant – STAT (free)
High Pevalence Rate of Digestive Tract Bacteria in Duodenoscopes: A Nationwide Study
20 Apr, 2018 | 00:48h | UTCHigh prevalence rate of digestive tract bacteria in duodenoscopes: a nationwide study -Endoscopy (free)
Commentary: Cleaned endoscopes often contaminated – Reuters (free)
Related Article: Residual moisture and waterborne pathogens inside flexible endoscopes: Evidence from a multisite study of endoscope drying effectiveness – American Journal of Infection Control (link to abstract – $ for full-text)