Gastroenterology (all articles)
Guideline: Endoscopic Management of Lynch Syndrome and Familial Risk of Colorectal Cancer
16 Oct, 2019 | 08:35h | UTC
Cardiovascular Risk in Fatty Liver Disease: The Liver-Heart Axis—Literature Review
15 Oct, 2019 | 08:23h | UTC
Extrahepatic Complications of Non-alcoholic Fatty Liver Disease
15 Oct, 2019 | 08:14h | UTC
Study: Non-alcoholic Fatty Liver Disease and Risk of Incident Acute Myocardial Infarction and Stroke
15 Oct, 2019 | 08:08h | UTC
[Abstract Only] Another Large Cohort Study Suggests Patients with Low-Risk Adenomas are Not At Increased Risk of Colorectal Cancer
10 Oct, 2019 | 09:26h | UTCLong-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text)
Commentary: High-, low-risk adenomas could inform colonoscopy intervals – Healio (free registration required)
Related Studies: Cohort Study: Individuals with 1 or 2 Small Adenomas at Baseline Screening Colonoscopy Have a Similar Risk of Advanced Neoplasia over 10 years as Individuals with no Baseline Adenomas (link to abstract) AND Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)
[Abstract Only] Review: Colonoscopy Adverse Events
10 Oct, 2019 | 09:17h | UTCColonoscopy Adverse Events – NEJM Journal Watch (free)
Original Article: ASGE review of adverse events in colonoscopy – GIE Gastrointestinal Endoscopy (link to abstract – $ for full-text)
NICE Guideline: Gastroesophageal Reflux Disease in Children and Young People
9 Oct, 2019 | 10:46h | UTC
British Society of Gastroenterology Guidelines on the Management of Inflammatory Bowel Disease
7 Oct, 2019 | 06:10h | UTCRelated Guidelines: Evidence-based clinical practice guidelines for inflammatory bowel disease – Journal of Gastroenterology (free) AND Ulcerative colitis: management – National Institute for Health and Care Excellence (free) AND ACG Clinical Guideline: Ulcerative Colitis in Adults – American Journal of Gastroenterology (free) AND AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis – Gastroenterology (free) AND Updated S3-Guideline Ulcerative Colitis. German Society for Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie (free) AND Management of Paediatric Ulcerative Colitis (free) AND Crohn’s disease: management – National Institute for Health and Care Excellence (free) AND ACG Clinical Guideline: Management of Crohn’s Disease in Adults – The American Journal of Gastroenterology (free) AND Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Luminal Crohn’s Disease – Journal of the Canadian Association of Gastroenterology (free)
Meta-Analysis: Predictors of Gastrointestinal Bleeding in Adult ICU Patients
7 Oct, 2019 | 05:47h | UTCSource: Grupo UTIclínica – HCFMUSP
Global Burden of Non-typhoidal Salmonella Invasive Disease
7 Oct, 2019 | 00:57h | UTCInvited Commentary: Non-typhoidal salmonella: invasive, lethal, and on the loose (free)
Related Commentary on Twitter
According to a recent study in @TheLancetInfDis, there were 535,000 cases of non-typhoidal #salmonella invasive disease in 2017. Nearly 80% of these cases occurred in sub-Saharan Africa. Read more: https://t.co/T5B79kIM2z pic.twitter.com/VtP60BfSHd
— IHME at UW (@IHME_UW) October 4, 2019
[Abstract Only] Randomized Trial: Single Dose of Ivermectine Preferred over Multiple Doses for Non-disseminated Strongyloidiasis
4 Oct, 2019 | 07:13h | UTCMultiple-dose versus single-dose ivermectin for Strongyloides stercoralis infection (Strong Treat 1 to 4): a multicentre, open-label, phase 3, randomised controlled superiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Related Commentary on Twitter
New online: Multiple-dose versus single-dose ivermectin for Strongyloides stercoralis infection (Strong Treat 1 to 4): a multicentre, open-label, phase 3, randomised controlled superiority trial https://t.co/ZGXvtA5Hps
— The Lancet Infectious Diseases (@TheLancetInfDis) September 24, 2019
BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy
3 Oct, 2019 | 07:45h | UTCEditorial: Personalised and risk based cancer screening (free)
Related Study: Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study – The BMJ (free)
Commentaries: Guideline Moves Away from Colorectal Cancer Screening for Some – NEJM Journal Watch (free) AND First Guideline to Say Colon Cancer Screening Is Not for All – Medscape (free registration required)
Related Guidelines: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)
Related Commentary on Twitter
Routine testing for bowel cancer should not be recommended for everyone aged 50-79 years because, for those at very low risk, the benefit is small and uncertain and there are potential harms, finds new #RapidRecs guideline https://t.co/68xTtEDHxQ
— The BMJ (@bmj_latest) October 3, 2019
[Abstract Only] Randomized Trial: Low-FODMAP Diet is Safe and Effective for Managing Persistent Gut Symptoms in Patients with Inflammatory Bowel Disease
2 Oct, 2019 | 22:23h | UTCEffects of Low-FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial – Gastroenterology (link to abstract – $ for full-text)
Commentary: FODMAPs diet relieves symptoms of inflammatory bowel disease – King’s College London (free)
FDA Warns About Rare Occurrence of Serious Liver Injury with Use of Hepatitis C Medicines in Some Patients with Advanced Liver Disease
2 Oct, 2019 | 01:41h | UTCCommentary: Hepatitis C medicines have led to liver decompensation in some patients – ACP Gastroenterology (free)
Randomized Trial: Prophylactic Hemoclips Not Beneficial for Prevention of Important Delayed Post-Polypectomy Bleeding in Patients with Large Colonic Polyps
2 Oct, 2019 | 01:24h | UTCEfficacy of Prophylactic Hemoclips in Prevention of Delayed Post-Polypectomy Bleeding in Patients With Large Colonic Polyps – Gastroenterology (link to abstract – $ for full-text)
See related study with conflicting results: Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial (link to abstract – $ for full-text)
Source: EvidenceAlerts
Related Commentary on Twitter
To clip or not clip after polypectomy? Two recent large clinical trials give us some clues. Cost-effectiveness studies for high-risk patients are awaited https://t.co/S6xY3ia1oB https://t.co/6vEs8k8Hcx
— Digestivo Hospital Universitario Ramón y Cajal (@DigestivoHRyC) July 7, 2019
Randomized Trial: Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps
2 Oct, 2019 | 01:22h | UTCClip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial – Gastroenterology (free for a limited period)
See related study with conflicting results: Randomized Trial: Prophylactic Hemoclips Not Beneficial for Prevention of Important Delayed Post-Polypectomy Bleeding in Patients with Large Colonic Polyps (free for a limited period)
Source: EvidenceAlerts
Related Commentary on Twitter
To clip or not clip after polypectomy? Two recent large clinical trials give us some clues. Cost-effectiveness studies for high-risk patients are awaited https://t.co/S6xY3ia1oB https://t.co/6vEs8k8Hcx
— Digestivo Hospital Universitario Ramón y Cajal (@DigestivoHRyC) July 7, 2019
International Consensus Conference on Stool Banking for Fecal Microbiota Transplantation in Clinical Practice
1 Oct, 2019 | 00:40h | UTC
Systematic Review: Azathioprine and 6‐mercaptopurine for Maintenance of Surgically‐induced Remission in Crohn’s Disease
1 Oct, 2019 | 00:34h | UTCAzathioprine and 6‐mercaptopurine for maintenance of surgically‐induced remission in Crohn’s disease – Cochrane Library (free)
Summary: Azathioprine and 6-mercaptopurine for the maintenance of surgically-induced remission in Crohn’s disease – Cochrane Library (free)
[Abstracts Only] Biologics Found to be Effective for Ulcerative Colitis in Industry-funded Trials
30 Sep, 2019 | 00:11h | UTCSee also: Ulcerative Colitis: One Biologic Investigated, Two Others Compared – NEJM Journal Watch (free)
Original Studies: Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis – New England Journal of Medicine (link to abstract – $ for full-text) AND Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis – New England Journal of Medicine (link to abstract – $ for full-text)
Clinical Approach to Lactose Intolerance
27 Sep, 2019 | 08:31h | UTCClinical Approach to Lactose Intolerance – JAMA (free for a limited period)
Related Reviews: Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management – Gut (free) AND Lactose Intolerance, Dairy Avoidance, and Treatment Options – Nutrients (free)
[Abstract Only] Cost-Effectiveness Analysis: High-Intensity Versus Low-Intensity Surveillance for Patients with Colorectal Adenomas
26 Sep, 2019 | 08:29h | UTCHigh-Intensity Versus Low-Intensity Surveillance for Patients With Colorectal Adenomas: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Model supports high-intensity surveillance after detection of colorectal adenomas – ACP Internist (free) AND High-intensity surveillance colonoscopy reduces CRC risk, is cost-effective for patients with colorectal adenomas – American College of Physicians (free)
Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C Virus Infection in Chronic Kidney Disease: Synopsis of the KDIGO 2018 Clinical Practice Guideline
24 Sep, 2019 | 08:23h | UTCOriginal Guideline: KDIGO 2018 Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease – Kidney International (free)
Randomized Trial: Treatments for Helicobacter pylori Infection Compared
24 Sep, 2019 | 07:47h | UTC
Guideline: Diagnosis of Chronic Anemia in Gastrointestinal Disorders
23 Sep, 2019 | 01:09h | UTC
[Abstract Only] Study: Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys
19 Sep, 2019 | 08:10h | UTCNational Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys – Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentaries: HCV-Infected Donor Kidneys Offer Good Short-Term Graft Function – Renal & Urology News (free) AND Hepatitis C-infected kidneys function as well as others after transplant, study says – CNN (free) AND Hepatitis C-Infected Kidneys Function Similar to Uninfected Organs One Year After Transplant – Penn Medicine (free) AND Kidney Transplants from Donors with HCV Safe and Functional 1 Year Post-Transplantation – American Society of Nephrology (ASN) (free)
Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries)