Gastroenterology (all articles)
Meta-analysis: High-quality evidence supports fecal microbiota transplantation is effective for recurrent Clostridioides difficile infection
6 Dec, 2020 | 23:35h | UTC
Randomized trial: A low-fat vegan diet can reduce body weight and improve insulin sensitivity in overweight adults
2 Dec, 2020 | 07:16h | UTCCommentary: Plant-based diet ramps up metabolism, according to new study – Physicians Committee for Responsible Medicine
State of the art review: Advances in the diagnosis and management of gastroesophageal reflux disease
30 Nov, 2020 | 00:52h | UTCAdvances in the diagnosis and management of gastroesophageal reflux disease – The BMJ (free for a limited period)
Randomized trial: Colorectal cancer screening with repeated fecal immunochemical tests detects more colorectal cancer and advanced adenomas compared to screening sigmoidoscopy
25 Nov, 2020 | 09:05h | UTCColorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial – Gastroenterology (link to abstract – $ for full-text)
[Abstract Only] In a Phase 2 randomized trial, Semaglutide at high doses improved Nonalcoholic Steatohepatitis (NASH), but with no significant beneficial effects in liver fibrosis
17 Nov, 2020 | 09:31h | UTCA Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Semaglutide Shows Promise in NASH Phase 2 Study – Medscape (free registration required)
Commentary on Twitter
https://twitter.com/NEJM/status/1327238536001593346
[Abstract Only] Randomized trial: Intravenous haloperidol more effective than ondansetron for cannabis hyperemesis syndrome
11 Nov, 2020 | 09:08h | UTC
Commentary on Twitter
Excited to have been involved in this practice-changing RCT comparing Haloperidol (superior) to Ondansetron for Cannabis Hyperemesis Syndrome from @Qemerg @therealdraa_ron @savforrester Marco Sivilotti and others! Check it out!https://t.co/ylms5JIO9v
— Andrew K Hall (@AKHallMD) November 5, 2020
Guideline synopsis for follow-up colonoscopy after polypectomy. Repeat Col in 7 to 10 y after 1 to 2 tubular adenomas (TA) < 10 mm; Repeat Col in 3 to 5 y after 3 to 4 TA < 10 mm; Repeat Col in 3 y after 5 to 10 TA < 10 mm; Repeat Col in 3 years after 1 or more TA > 10 mm
9 Nov, 2020 | 01:17h | UTCRecommendations for Follow-up Colonoscopy After Polypectomy – JAMA (free for a limited period)
Author interview: New Recommendations for How Often to Repeat Colonoscopy Following Polypectomy
Original guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology
USPSTF draft statement now recommends starting colorectal cancer screening at 45
28 Oct, 2020 | 08:57h | UTCDraft Recommendation Statement: Colorectal Cancer Screening – U.S. Preventive Services Task Force
Commentaries: Colorectal cancer screening should start five years earlier — at 45 — expert panel says – STAT AND USPSTF Lowers Colorectal Cancer Screening Age to 45 in Draft Recommendation – NEJM Journal Watch
Clinical review: New advances in the diagnosis and management of hepatocellular carcinoma
28 Oct, 2020 | 08:47h | UTCNew advances in the diagnosis and management of hepatocellular carcinoma – The BMJ (free for a limited period)
Commentary on Twitter
https://twitter.com/bmj_latest/status/1320817899599241216
Meta-analysis: Drugs for preventing postoperative nausea and vomiting in adults after general anesthesia
21 Oct, 2020 | 09:13h | UTC
Commentary on Twitter
Very pleased to share our new #NMA on drugs for preventing #postoperative #nausea and #vomiting after general #anaesthesia: https://t.co/vwha2Vd3DL A huge effort (585 studies!), that involved assessing and ranking the effects of 28 drugs and 36 drug combinations from 6 classes.
— Cochrane Anaesthesia & Emergency and Critical Care (@Cochrane_ACE) October 20, 2020
Systematic review: Management of colonic diverticulitis
16 Oct, 2020 | 09:25h | UTCManagement of Colonic Diverticulitis – Agency for Healthcare Research and Quality
Full report: Management of Colonic Diverticulitis
Evidence summary: Management of Colonic Diverticulitis
Non-respiratory presentations of COVID-19, a clinical review
14 Oct, 2020 | 09:33h | UTC
Esophageal emergencies: Another important cause of acute chest pain
12 Oct, 2020 | 00:30h | UTCEsophageal emergencies: another important cause of acute chest pain – Insights into Imaging
[Abstract Only] A Randomized trial comparing antibiotics with appendectomy for appendicitis
6 Oct, 2020 | 00:44h | UTCA Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Benefits, risks seen with antibiotics-first for appendicitis – University of Washington School of Medicine
Infographic: Deciding Between Antibiotics & Surgery for Appendicitis: Findings from the CODA Study
Commentary on Twitter
For the treatment of appendicitis, antibiotics noninferior to appendectomy on the basis of results of a standard health-status measure. In the antibiotics group, nearly 3 in 10 participants had undergone appendectomy by 90 days. #ACSCC20
— NEJM (@NEJM) October 5, 2020
Virologists who discovered hepatitis C win medicine Nobel
6 Oct, 2020 | 00:12h | UTCVirologists who discovered hepatitis C win medicine Nobel – Nature
See also: Medicine Nobel honors three scientists for discoveries on hepatitis C virus – Science AND Trio wins Nobel Prize in medicine for discovery of hepatitis C virus – STAT
Cohort study: Fecal microbiota transplant is highly effective in real-world practice
4 Oct, 2020 | 23:10h | UTCFecal Microbiota Transplant is Highly Effective in Real-World Practice: Initial Results from the FMT National Registry – Gastroenterology (link to abstract – $ for full-text)
Commentary: 9 in 10 Cured a Month After Fecal Microbiota Transplantation for C. diff – NEJM Journal Watch
Editorial – Stress ulcer prophylaxis: Is mortality a useful endpoint?
30 Sep, 2020 | 09:31h | UTCStress ulcer prophylaxis: Is mortality a useful endpoint? – Intensive Care Medicine
Commentary on Twitter
Stress ulcer prophylaxis: restrict to highest GI bleeding risk #ICU pts; still uncertainties on harmful effects (ie PK interactions?). Early EN, effective if low-risk + reducing underfeeding, to be encouraged. https://t.co/2EOsefikFc
Referring Wang et al https://t.co/MXnfHYyoJ4 pic.twitter.com/Xz8wmTzn62
— Intensive Care Medicine (@yourICM) September 29, 2020
Gastrointestinal complications in critically ill patients with and without COVID-19
25 Sep, 2020 | 02:44h | UTCGastrointestinal Complications in Critically Ill Patients With and Without COVID-19 – JAMA
Commentary on Twitter
https://twitter.com/LMaurerMD/status/1309185925692481536
Lower-dose zinc for childhood diarrhea — a randomized, multicenter trial
24 Sep, 2020 | 09:21h | UTC
Commentary on Twitter
In this randomized trial involving children in Tanzania and India, 5 mg and 10 mg of daily zinc were noninferior to 20 mg of zinc for diarrhea and resulted in less vomiting.
— NEJM (@NEJM) September 23, 2020
Things we do for no reason: Routine correction of elevated INR and thrombocytopenia prior to paracentesis in patients with cirrhosis
24 Sep, 2020 | 09:17h | UTCSee collection: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine
Multisystem effects of COVID-19: A concise review for practitioners
16 Sep, 2020 | 09:14h | UTCMultisystem effects of COVID-19: A concise review for practitioners – Postgraduate Medicine
State of the art review: Hepatorenal syndrome
15 Sep, 2020 | 08:41h | UTCHepatorenal syndrome: pathophysiology, diagnosis, and management – The BMJ (free for a limited period)
Commentary on Twitter
Hepatorenal syndrome is a serious complication of cirrhosis that is associated with high morbidity and mortality. This review discusses its definition, pathophysiology, diagnosis, and management of hepatorenal syndromehttps://t.co/m9QnH6n2lJ
— The BMJ (@bmj_latest) September 14, 2020
ACG Guidelines: Diagnosis and management of achalasia
11 Sep, 2020 | 01:18h | UTC
Commentary on Twitter
New ACG Clinical Guideline on the Diagnosis and Management of Achalasia in The American Journal of #Gastroenterology
Full guideline here: https://t.co/7dnQVIA5zk#AmJGastro #EsophagealMotility #MotilityDisorders @BrennanSpiegel @JPandolfinoMD @RenaYadlapati @KatarinaGreer2 pic.twitter.com/zn0eVuxrQr
— ACG (@AmCollegeGastro) September 4, 2020
[Abstract Only] Randomized trial: Aspirin increases major GI bleeding risk by 60% in older individuals
6 Sep, 2020 | 21:30h | UTCSource: EvidenceAlerts
Commentary on Twitter
Aspirin increases GI bleeding risk by 60% in an aspirin RCT
137 total GI bleeds in 90000 person years @Gut_BMJ https://t.co/Hb8h6kZrpo
— Elliot Tapper (@ebtapper) August 8, 2020
[Preprint] Diarrhea and vomiting may be a key sign of Covid-19 in children
4 Sep, 2020 | 02:12h | UTCDiarrhoea and vomiting may be key sign of Covid in children – The Guardian
Original Study: Seroprevalence of SARS-CoV-2 antibodies in children – A prospective multicentre cohort study – medRxiv
Commentary on Twitter
(1/10) Important pre-print study (interpret cautiously) of 992 UK children showing 6.9% had #SARSCoV2 antibodies, suggesting they are at similar risk of infection as adults, & that young and older children are similarly susceptible. 50% were asymptomatic.https://t.co/sUgvIlnmE0 pic.twitter.com/nxeHkAODLF
— Dr Zoë Hyde (@DrZoeHyde) September 3, 2020