Hepatology
Cohort Study | Taiwan’s nationwide Hepatitis B vaccination and antiviral therapy program reduced end-stage liver disease burden.
25 Jul, 2022 | 12:54h | UTC
Commentary on Twitter
This cohort study found the nationwide implementation of hepatitis B vaccination (1984) and antiviral treatment programs (2003) was followed by dramatic reductions in the burden of end-stage liver disease in Taiwan. https://t.co/Qnei2abi85
— JAMA Network Open (@JAMANetworkOpen) July 18, 2022
M-A | Evidence on indications and techniques to increase the future liver remnant in children undergoing extended hepatectomy.
22 Jul, 2022 | 11:33h | UTC
Review | Liver biopsy in patients with alcohol-associated liver disease with acute-on-chronic liver failure.
22 Jul, 2022 | 11:28h | UTC
An approach to the management of diabetes mellitus in cirrhosis: a primer for the hepatologist.
22 Jul, 2022 | 11:26h | UTC
Review | Clinical implications, evaluation, and management of hyponatremia in cirrhosis.
21 Jul, 2022 | 12:53h | UTC
Review | Fatigue in cirrhosis.
21 Jul, 2022 | 12:52h | UTCFatigue in Cirrhosis – Journal of Clinical and Experimental Hepatology
Review and Clinical Guidance | Respiratory events with Terlipressin and albumin in hepatorenal syndrome.
19 Jul, 2022 | 13:32h | UTC
Cystic liver lesions: a pictorial review.
18 Jul, 2022 | 10:48h | UTCCystic liver lesions: a pictorial review – Insights into Imaging
WHO Updated Report | Severe acute hepatitis of unknown etiology in children.
14 Jul, 2022 | 12:54h | UTCSevere acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Related:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
A case series of children with acute hepatitis and human Adenovirus infection.
14 Jul, 2022 | 12:56h | UTCA Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Related Study: Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 — Two studies point to a suspiciously high prevalence – MedPage Today (free registration required)
Commentaries on Twitter
A majority of children admitted to a single hospital in late 2021–early 2022 with acute hepatitis of unknown cause tested positive for adenovirus. This report describes the children’s illnesses and outcomes. https://t.co/QYvi6U1jUN pic.twitter.com/auPRq1duQm
— NEJM (@NEJM) July 13, 2022
From January–April 2022, 44 children with acute hepatitis of unknown cause were referred to a liver-transplantation center in the U.K. Six underwent liver transplantation. https://t.co/CMI4KCqdxM pic.twitter.com/og72u58L5R
— NEJM (@NEJM) July 13, 2022
Consensus on the management of complications of cirrhosis of the liver in pediatrics.
11 Jul, 2022 | 12:24h | UTC
Review | Gallstone disease in cirrhosis – Pathogenesis and management.
7 Jul, 2022 | 12:21h | UTC
Review | Tuberculosis in cirrhosis – A diagnostic and management conundrum.
7 Jul, 2022 | 12:18h | UTC
RCT | Odevixibat treatment in progressive familial intrahepatic cholestasis.
6 Jul, 2022 | 11:35h | UTCInvited Commentary: The first new drug for progressive familial intrahepatic cholestasis – The Lancet Gastroenterology & Hepatology (free registration required)
Commentary on Twitter
New research – Thompson et al – Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial (PEDFIC 1)https://t.co/hPLmPLMcDt#livertwitter #cholestasis #PFIC pic.twitter.com/oUMMh1H0kv
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) July 1, 2022
Review | Liver transplantation in alcohol-related liver disease and alcohol-related hepatitis.
6 Jul, 2022 | 11:22h | UTCIndeterminate pediatric acute liver failure: clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022.
5 Jul, 2022 | 12:09h | UTCRelated:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Review | Preoperative evaluation and management of patients with select chronic gastrointestinal, liver, and renal diseases.
5 Jul, 2022 | 12:16h | UTCRelated:
Preoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings
Preoperative Management of Surgical Patients Using Dietary Supplements – Mayo Clinic Proceedings
Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings
Preoperative Cardiac Risk Assessment – Mayo Clinic Proceedings
Preoperative Evaluation Before Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Cardiac Risk Reduction in Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings
Review | Artificial intelligence in hepatology – ready for the primetime.
5 Jul, 2022 | 11:30h | UTCBrief Review | Sudden onset hepatitis in children.
4 Jul, 2022 | 12:41h | UTCSudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Related: WHO Updated Report: Severe acute hepatitis of unknown etiology in children. (several articles on the subject)
Commentary on Twitter
NEW! In this COMMENT by @ZaniaStamataki & @kellyda60 summarise what we know so far about sudden onset #hepatitis of unexplained origin in childrenhttps://t.co/AYTR8wrG3C
Read-only link https://t.co/dgyzRhpODT#paediatrics pic.twitter.com/1WLQfaRrdx
— Nature Reviews Gastroenterology & Hepatology (@NatRevGastroHep) July 1, 2022
WHO Updated Report: Severe acute hepatitis of unknown etiology in children.
28 Jun, 2022 | 11:23h | UTCSevere acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Related:
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Phase 2 single-arm study: Fazirsiran for liver disease associated with Alpha1-Antitrypsin deficiency.
27 Jun, 2022 | 11:19h | UTCFazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In this small trial in adults with ATT deficiency, fazirsiran was associated with a strong reduction of mutant AAT levels in the serum and liver and concurrent improvements in liver enzyme levels. #ILC2022 https://t.co/RibsKzOQfO pic.twitter.com/BnMcSyfVcq
— NEJM (@NEJM) June 25, 2022
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.
27 Jun, 2022 | 11:17h | UTCCommentary: Chronic Hepatitis B Infections Decreasing in Recent Years – HCP Live
Commentary on Twitter
New research from #GBDStudy – Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019https://t.co/e0oxlT2gKd#hepB #HBV #nohep #livertwitter @IHME_UW pic.twitter.com/V8h1LrCoUQ
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 21, 2022
Guideline review: EASL clinical practice guidelines: drug-induced liver injury.
22 Jun, 2022 | 11:27h | UTCOriginal Article: EASL Clinical Practice Guidelines: Drug-induced liver injury – Journal of Hepatology