Family Medicine
Cohort Study: Cardiometabolic multimorbidity linked to accelerated cognitive decline and dementia progression.
21 Jun, 2022 | 10:59h | UTCNews Release: Diabetes and cardiovascular disease increase dementia risk – Karolinska Institutet
Related:
Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text) AND Commentary: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology
Preventing dementia: what’s the evidence? – Evidently Cochrane
Safety of bariatric surgery in patients with previous acute coronary events or heart failure: nationwide cohort study.
21 Jun, 2022 | 10:44h | UTC
Commentary on Twitter
#Bariatric surgery improves metabolic health of patients, but what are the risks if they have had MI before surgery?
National dataset matched 16000 pts🇸🇪
Heart dis assoc w/🔼 cardiac events post op, plus 🔼risk of SBO and stricture.#SoMe4Surgery https://t.co/iHsZiHIgdG pic.twitter.com/v2SXMpcZd3— BJS Open (@BjsOpen) June 17, 2022
Cohort Study: Association of obsessive-compulsive disorder and obsessive-compulsive symptoms with substance misuse.
21 Jun, 2022 | 10:42h | UTC
Commentary on Twitter
In this Swedish cohort study, individuals with OCD diagnosis had a nearly 4-fold risk of substance use disorders, substance-related criminal convictions or deaths. The association was partially accounted for by shared genetics. https://t.co/BDwKw227FG
— JAMA Network Open (@JAMANetworkOpen) June 6, 2022
M-A: Benefits and risks of rapid initiation of antiretroviral therapy in patients with HIV.
21 Jun, 2022 | 10:41h | UTC
M-A: Overweight/obesity in childhood and the risk of early puberty.
21 Jun, 2022 | 10:36h | UTCRelated Study: Patterns of Early Life Weight Gain and Female Onset of Puberty – Journal of the Endocrine Society
Cluster RCT: Evaluation of a multicomponent intervention consisting of education and feedback to reduce benzodiazepine prescriptions by general practitioners.
21 Jun, 2022 | 10:29h | UTC
Associations of bilateral vestibulopathy with cognition in older adults matched with healthy controls for hearing status.
21 Jun, 2022 | 10:24h | UTC
Commentary on Twitter
In this study, older adults with #bilateralvestibulopathy had worse #cognition than their matched control. These results support an association between vestibular loss and cognitive impairment, in particular #Alzheimerdisease. https://t.co/atHR8QlWD9
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) June 17, 2022
WHO Situation Update: Multi-country monkeypox outbreak.
20 Jun, 2022 | 10:45h | UTCMulti-country monkeypox outbreak: situation update – World Health Organization
Related:
Monkeypox Genital Lesions – New England Journal of Medicine
Monkeypox vaccination begins — can the global outbreaks be contained? – Nature
Incubation period for monkeypox: Estimates from the Netherlands.
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
Rename monkeypox strains to remove geographic stigma, researchers say – Science
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
WHO report highlights urgent need to transform mental health and mental health care.
20 Jun, 2022 | 10:47h | UTCNews Release: WHO highlights urgent need to transform mental health and mental health care – World Health Organization
Report: World mental health report: Transforming mental health for all – World Health Organization
Commentary: Urgent Need to Transform Mental Health Care – WHO Says In Largest Review Ever – Health Policy Watch
Commentary on Twitter (thread – click for more)
WHO calls on all stakeholders to work together to deepen the value and commitment given to #MentalHealth, reshape the environments that influence mental health and strengthen the systems that care for people’s mental health: WHO #WorldMentalHealthReport https://t.co/J856BrylBB
— World Health Organization (WHO) (@WHO) June 17, 2022
Opinion | Normalizing menopause – “Martha Hickey and colleagues argue that social and cultural attitudes contribute to the varied experience of menopause and that medicalization fuels negative perceptions”.
20 Jun, 2022 | 10:38h | UTCNormalizing menopause – The BMJ (free for a limited period)
News Release: Medicalizing menopause may be unhelpful for some women – British Medical Journal
Commentary: Menopause is not a disease. Experts call for new narrative for this natural stage of a woman’s life – CNN
Cohort Study: Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes.
20 Jun, 2022 | 10:36h | UTC
Commentary on Twitter
Still remember working on this in 2019 but it's out today!
Gamma-GT level has a strong association with mortality outcomes and could add to the prediction of CV mortality
https://t.co/0lzqGfgiGc pic.twitter.com/C8tSZLWlI2— Fred Ho (@fredho42) May 13, 2022
Under a CC BY-NC-ND 4.0 license
Case-control study: Risk of long COVID associated with delta vs. omicron variants of SARS-CoV-2.
20 Jun, 2022 | 10:34h | UTCRisk of long COVID associated with delta versus omicron variants of SARS-CoV-2 – The Lancet
News Release: Long COVID risk less during Omicron compared to Delta, study finds – King’s College London
Commentaries:
Omicron less likely to lead to long COVID, study finds – CIDRAP
Covid-19: Long covid risk is lower with omicron than delta, researchers find – The BMJ
Commentary on Twitter
Substantial (~50-75%) reduction of #LongCovid with Omicron compared with Delta variant, magnitude influenced by age and time since vaccination @TheLancet https://t.co/shAzJn8WSj pic.twitter.com/bXoct0sXd1
— Eric Topol (@EricTopol) June 17, 2022
Systematic Review: Clinical judgement by primary care physicians for the diagnosis of all‐cause dementia or cognitive impairment in symptomatic people.
20 Jun, 2022 | 01:18h | UTCSummary: Why is improving dementia diagnosis important? – Cochrane Library
AHA Scientific Statement: Revascularization for renovascular disease.
17 Jun, 2022 | 11:50h | UTCTop Things to Know: Revascularization for Renovascular Disease – American Heart Association
Commentary: When is Renovascular Hypertension Amenable to Revascularization – American Heart Association
FDA advisers OK COVID-19 vaccines for youngest kids.
17 Jun, 2022 | 11:43h | UTCFDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP
See also: FDA advisers endorse 1st COVID-19 shots for kids under 5 – Associated Press
Test-negative, case–control study: Effects of previous infection and vaccination on symptomatic omicron infections.
17 Jun, 2022 | 11:44h | UTCRelated:
Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine
Two new studies show vaccination provides additional protection after Covid-19 infection.
Commentary on Twitter
A study in Qatar assessed the effectiveness of previous infection, vaccination, and both against symptomatic SARS-CoV-2 caused by omicron BA.1 and BA.2 and against severe, critical, or fatal #COVID19. https://t.co/bEVD3Y1sUn pic.twitter.com/Y38a0xxead
— NEJM (@NEJM) June 15, 2022
Incubation period for monkeypox: Estimates from the Netherlands.
17 Jun, 2022 | 11:41h | UTCNews Release: Incubation period for monkeypox: Estimates from the Netherlands – European Centre for Disease Prevention and Control (ECDC)
Original Study: Estimated incubation period for monkeypox cases confirmed in the Netherlands, May 2022 – Eurosurveillance
Commentary on Twitter (thread – click for more)
Our early investigation from @rivm on the incubation period for #monkeypox is now available @Eurosurveillanc.https://t.co/Vr9AChIAOV
Main finding: the mean incubation period was 8.5 days (5th to 95th percentiles: 4.2 to 17.3 days).
Details, caveats, and a few thoughts ⬇️🧵1/
— Fumi Miura (@FuminariMiura) June 16, 2022
Does this patient with acute infectious conjunctivitis have a bacterial infection? The rational clinical examination systematic review.
17 Jun, 2022 | 11:12h | UTCDoes This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)
Commentary on Twitter
In this review, bacterial conjunctivitis was more common than viral conjunctivitis in children and viral conjunctivitis was more common than bacterial conjunctivitis in adults, although the prevalence estimates were based on limited evidence. https://t.co/wJ6YXxPRem
— JAMA (@JAMA_current) June 16, 2022
Cohort Study: Association of sitting time with mortality and cardiovascular events in high-income, middle-income, and low-income countries.
17 Jun, 2022 | 11:05h | UTCAssociation of Sitting Time With Mortality and Cardiovascular Events in High-Income, Middle-Income, and Low-Income Countries – JAMA Cardiology (free for a limited period)
Commentary: Trade the chair for fresh air: Sitting time and cardio health – Simon Fraser University
Commentary from one of the authors on Twitter
Our study in 105K people from #PURE study:
🌟⬆️ sitting associated with >early death & heart disease
🌟association > in low income countries
🌟being active can counteract risk
🌟every 30 min of sitting replaced by #exercise, risk⬇️ 2%#healthy@JAMACardio: https://t.co/rR61SolkXs pic.twitter.com/ESUFXy6Pvj— Scott Lear, PhD (@DrScottLear) June 15, 2022
NICE Guideline: Reducing sexually transmitted infections.
16 Jun, 2022 | 11:15h | UTCReducing sexually transmitted infections – National Institute for Health and Care Excellence
Inappropriate sinus tachycardia: etiology, pathophysiology, and management.
16 Jun, 2022 | 11:05h | UTC
Perspective | Viruses that were on hiatus during Covid are back — and behaving in unexpected ways.
16 Jun, 2022 | 11:06h | UTCViruses that were on hiatus during Covid are back — and behaving in unexpected ways – STAT
RCT: Effect of legumes in energy reduced dietary approaches to stop hypertension (DASH) diet on blood pressure among overweight and obese type 2 diabetic patients.
16 Jun, 2022 | 10:41h | UTC
Pfizer’s Paxlovid study fails to answer key questions over benefit for broader populations.
15 Jun, 2022 | 11:22h | UTCPfizer’s Paxlovid study fails to answer key questions over benefit for broader populations – STAT
RCT: Effectiveness and safety of lotion, cream, gel, and ointment emollients for childhood eczema.
15 Jun, 2022 | 11:20h | UTCNews Release: The right moisturiser for children with eczema is the one that they like to use, study finds – University of Nottingham
Commentary: Lotion, Cream, Gel, and Ointment Similarly Effective for Childhood Eczema – HealthDay
Commentary on Twitter
New: @bee_study led by @riddmj found no difference in effectiveness between the four main types of emollients —lotions, creams, gels, and ointments—for childhood #eczema
The right #moisturizer is the one that children will use. https://t.co/45N5A136Kx
— The Lancet Child & Adolescent Health (@LancetChildAdol) May 24, 2022