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Cross-Sectional Study | Hypertension common among poorest, least educated around the world.

22 Aug, 2022 | 12:14h | UTC

The Association of Socioeconomic Status With Hypertension in 76 Low- and Middle-Income Countries – Journal of the American College of Cardiology (link to abstract – $ for full-text)

News Release: Hypertension Common Among Poorest, Least Educated Around the World – American College of Cardiology

Editorial: Hypertension—A Silent Killer Without Global Bounds: What Next? – Journal of the American College of Cardiology

Commentary: Hypertension Common Among Poorest, Least Educated Globally – HealthDay

 

Commentary on Twitter

 


RCT | Mepolizumab for urban children with exacerbation-prone eosinophilic asthma.

22 Aug, 2022 | 12:09h | UTC

Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial – The Lancet (link to abstract – $ for full-text)

Commentary: Mepolizumab Cuts Exacerbations in Children With Severe Asthma – HealthDay

 


Calcium for pre-eclampsia prevention | A systematic review and network meta-analysis to guide personalized antenatal care.

22 Aug, 2022 | 11:47h | UTC

Calcium for pre-eclampsia prevention: A systematic review and network meta-analysis to guide personalised antenatal care – British Journal of Obstetrics and Gynaecology

Related: WHO recommendation: Calcium supplementation during pregnancy for the prevention of pre-eclampsia and its complications – World Health Organization

 

Commentary on Twitter

 


AHA Scientific Statement outlines the most common symptoms of 6 cardiovascular diseases.

19 Aug, 2022 | 16:19h | UTC

State of the Science: The Relevance of Symptoms in Cardiovascular Disease and Research: A Scientific Statement From the American Heart Association – Circulation

News Release: Report outlines most common symptoms of 6 cardiovascular diseases – American Heart Association

Top Things to Know: State of the Science: The Relevance of Symptoms in CVD and Research – American Heart Association

Commentary: American Heart Association Scientific Statement on State-of-the-Science: The Relevance of Symptoms in Cardiovascular Disease and Research – American Heart Association

 


Study | Almost half of global cancer deaths are due to risk factors, with smoking, alcohol use, and high BMI the greatest contributors.

19 Aug, 2022 | 16:21h | UTC

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet

News Release: The Lancet: Almost half of global cancer deaths are due to risk factors, with smoking, alcohol use, and high BMI the greatest contributors – Institute for Health Metrics and Evaluation

 

Commentary on Twitter (thread – click for more)

 


Retrospective cohort study | Symptoms and risk factors for long COVID in non-hospitalized adults.

19 Aug, 2022 | 16:17h | UTC

Symptoms and risk factors for long COVID in non-hospitalized adults – Nature Medicine

Commentary: UK study finds over 100 symptoms of long COVID in non-hospitalized adults – News Medical

 


M-A | The accuracy of pulse oximetry in measuring oxygen saturation by levels of skin pigmentation.

19 Aug, 2022 | 16:15h | UTC

The accuracy of pulse oximetry in measuring oxygen saturation by levels of skin pigmentation: a systematic review and meta-analysis – BMC Medicine

Related:

Impact of ethnicity on the accuracy of measurements of oxygen saturations: A retrospective observational cohort study – eClinicalMedicine

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 


Cohort Study | Aldosterone linked to increased risk of chronic kidney disease progression and end-stage kidney disease.

19 Aug, 2022 | 16:09h | UTC

News Release: Aldosterone linked to increased risk of chronic kidney disease progression and end-stage kidney disease – European Society of Cardiology

Original Study: Aldosterone in chronic kidney disease and renal outcomes – European Heart Journal

Editorial: Aldosterone excess and cardiorenal risk: more common than appreciated – European Heart Journal

 

Commentary on Twitter

https://twitter.com/ESC_Journals/status/1556898902258991104

 


Developmental variability in autism across 17.000 autistic individuals and 4.000 siblings without an autism diagnosis: comparisons by cohort, intellectual disability, genetic etiology, and age at diagnosis.

19 Aug, 2022 | 16:06h | UTC

Developmental Variability in Autism Across 17 000 Autistic Individuals and 4000 Siblings Without an Autism DiagnosisComparisons by Cohort, Intellectual Disability, Genetic Etiology, and Age at Diagnosis – JAMA Pediatrics (link to abstract – $ for full-text)

Commentary: Timing of developmental milestones varies greatly in children with autism – Physician’s Weekly

 

Commentary on Twitter

 

Commentary on Twitter

 


RCT | A lower glycemic criteria in not better than higher glycemic criteria for the diagnosis of gestational diabetes.

18 Aug, 2022 | 13:04h | UTC

Lower versus Higher Glycemic Criteria for Diagnosis of Gestational Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Pros and cons with lower vs higher threshold for gestational diabetes diagnosis – medwire News

 

Commentary on Twitter (thread – click for more)

 


RCT | Metformin, Ivermectin, and Fluvoxamine are not beneficial for obese outpatients with Covid-19.

18 Aug, 2022 | 13:00h | UTC

Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19 – New England Journal of Medicine

Editorial: Time to Stop Using Ineffective Covid-19 Drugs – New England Journal of Medicine

 

Commentary on Twitter

 


Executive Summary | Guidelines for adrenalectomy.

18 Aug, 2022 | 12:58h | UTC

American Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary – JAMA Surgery (free for a limited period)

Author interview: American Association of Endocrine Surgeons Guidelines for Adrenalectomy – JAMA

 


Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

18 Aug, 2022 | 12:56h | UTC

Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study – The Lancet

Commentaries:

Treating monkeypox like an STI may help control the outbreak, but stigma is a danger – The Conversation

Anal and oral sex spread monkeypox. Let’s talk about it. – Vox

Related:

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 

Commentary on Twitter

 


Retrospective cohort study | Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy.

18 Aug, 2022 | 12:51h | UTC

Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy: population based retrospective cohort study – The BMJ

News Release: No link between COVID-19 vaccination in pregnancy and higher risk of preterm birth or stillbirth – British Medical Journal

Related:

SARS-CoV-2 infection and COVID-19 vaccination in pregnancy – Nature Reviews Immunology

Cohort Study: COVID-19 vaccination during early pregnancy was not associated with increased risk of congenital fetal anomalies.

Retrospective Cohort: A population-based study in Sweden and Norway did not find an increased risk of pregnancy complications after COVID-19 vaccination.

WHO Questions and Answers: COVID-19 vaccines and pregnancy.

COVID vaccines safely protect pregnant people: the data are in.

COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

 

Commentary on Twitter

 


M-A | Performance of confirmatory tests for diagnosing primary aldosteronism.

18 Aug, 2022 | 12:54h | UTC

Performance of Confirmatory Tests for Diagnosing Primary Aldosteronism: a Systematic Review and Meta-Analysis – Hypertension

 

Commentary on Twitter

https://twitter.com/HyperAHA/status/1559624529869160448

 


Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients.

18 Aug, 2022 | 12:49h | UTC

Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients – The Lancet Psychiatry

News Release: Increased risk of some neurological and psychiatric disorders remains two years after COVID-19 infection – University of Oxford

Commentary: Covid-19: Increased risk of some neurological and psychiatric disorders remains two years after infection, study finds – The BMJ

 

Commentary on Twitter

 


Modeling Study | Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030.

18 Aug, 2022 | 12:42h | UTC

Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study – BMJ Nutrition Prevention & Health

News Release: 1 g cut in daily salt intake could ward off nearly 9 million cases of stroke/heart disease in China – BMJ Newsroom

 


Preventing stillbirth: a review of screening and prevention strategies.

18 Aug, 2022 | 12:36h | UTC

Preventing Stillbirth: A Review of Screening and Prevention Strategies – Maternal-Fetal Medicine

 


Guideline | Recommendation on instrument-based screening for depression during pregnancy and the postpartum period.

17 Aug, 2022 | 14:39h | UTC

Recommendation on instrument-based screening for depression during pregnancy and the postpartum period – Canadian Medical Association Journal

Editorial: Do ask, but don’t screen: identifying peripartum depression in primary care – Canadian Medical Association Journal

News Release: Regular enquiry about well-being vs. universal screening recommended to detect depression in pregnancy and after birth – Canadian Medical Association Journal

See also: Canadian Task Force on Preventive Health Care page with summary and tools

 


Launch of first WHO position paper on optimizing brain health across life.

17 Aug, 2022 | 14:41h | UTC

News Release: Launch of first WHO position paper on optimizing brain health across life – World Health Organization

WHO position paper: Optimizing brain health across the life course – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

17 Aug, 2022 | 14:37h | UTC

Epidemiologic and Clinical Characteristics of Monkeypox Cases — United States, May 17–July 22, 2022 – Morbidity and Mortality Weekly Report

Commentaries:

CDC releases interim monkeypox guidance, reports epidemiologic and clinical characteristics – ACP Internist

Global experts race to understand rare cases when monkeypox leads to death – CNN

Related:

Update on the Monkeypox Outbreak – JAMA

Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 

Commentary on Twitter

 


CDC interim guidance for prevention and treatment of Monkeypox in persons with HIV infection.

17 Aug, 2022 | 14:36h | UTC

Interim Guidance for Prevention and Treatment of Monkeypox in Persons with HIV Infection — United States, August 2022 – Morbidity and Mortality Weekly Report

 


Review | Barrett Esophagus.

17 Aug, 2022 | 14:26h | UTC

Barrett Esophagus: A Review – JAMA (free for a limited period)

Audio clinical review: Barrett Esophagus – JAMA

Related: Diagnosis and Management of Barrett’s Esophagus: An Updated ACG Guideline – American Journal of Gastroenterology

 


Perspective | Is there an optimal diet for primordial prevention of atherosclerosis?

17 Aug, 2022 | 14:23h | UTC

Is there an optimal diet for primordial prevention of atherosclerosis? – European Journal of Cardiology

 


AAP Updated Clinical Report | The use of systemic and topical fluoroquinolones.

17 Aug, 2022 | 14:19h | UTC

The Use of Systemic and Topical Fluoroquinolones – Pediatrics

 


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