Family Medicine | Page 58 of 374 | Links Medicus Content Curation & Alerts in Medicine

Guideline Synopsis | AHA/ACC Guideline for the management of heart failure.

16 Sep, 2022 | 13:01h | UTC

Management of Heart Failure – JAMA (free for a limited period)

Original Article: #ACC22 – 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

RCT | Among neonates with probable bacterial infection, switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) was noninferior to a full course of intravenous antibiotics and resulted in shorter hospitalization (median duration of 3.4 vs. 6.8 days).

16 Sep, 2022 | 12:59h | UTC

Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

Commentary: Dutch team devise less painful ‘drip and drink’ antibiotics treatment for babies – Dutch News

Commentaries on Twitter

*New trial*—early switch to #OralAntibiotics is not inferior to full-course IV antibiotics in #neonates with probable bacterial infection; & adverse events were not increased with use of oral antibiotics

By @IKMReiss @karelallegaert & colleagues

https://t.co/2yzeh3ptuc pic.twitter.com/BgBosxfECC

— The Lancet Child & Adolescent Health (@LancetChildAdol) September 12, 2022

In term and near-term infants <28 days with probable bacterial infection, how safe is it to switch to oral Amox-Clav as opposed to completing a course of intravenous antibiotics? A new RCT in @Lancet tries to answer this question.https://t.co/M2Za54cfxF #EBNeoAlerts #NeoEBM pic.twitter.com/zKpIiW1Whx

— Evidence-Based Neo (@EBNEO) September 12, 2022

(Thread – click for more)

Efficacy & safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) vs full course of IV antibiotics in neonates with probable bacterial infection (RAIN):multicentre, randomised,open-label,non-inferiority trial -The Lancet https://t.co/mcyr9bILRq

— Prof. Dr. Sanjeev Bagai (@BagaiDr) September 13, 2022

Review | Obesity and contraceptive use: impact on cardiovascular risk.

16 Sep, 2022 | 12:53h | UTC

Obesity and contraceptive use: impact on cardiovascular risk – ESC Heart Failure

News Release: Combined birth control pill linked with increased risk of blood clots in obese women – European Society of Cardiology

Systematic Review | The effects of water compared with other solutions for wound cleansing – not enough evidence to guide recommendations.

16 Sep, 2022 | 12:52h | UTC

Water for wound cleansing – Cochrane Library

Summary: The effects of water compared with other solutions for wound cleansing – Cochrane Library

Global, regional, and national burdens of HIV and other sexually transmitted infections in adolescents and young adults aged 10–24 years from 1990 to 2019: a trend analysis based on the Global Burden of Disease Study 2019.

16 Sep, 2022 | 12:50h | UTC

Global, regional, and national burdens of HIV and other sexually transmitted infections in adolescents and young adults aged 10–24 years from 1990 to 2019: a trend analysis based on the Global Burden of Disease Study 2019 – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

Commentary on Twitter

New analysis of #GBD data reports the global incidence of #HIV and other #STIs in adolescents and young adults https://t.co/hSjgHMGg4R pic.twitter.com/JBd7Goa9Sa

— The Lancet Child & Adolescent Health (@LancetChildAdol) September 13, 2022

RCT | Effects of cocoa extract and a multivitamin on cognitive function.

15 Sep, 2022 | 13:14h | UTC

Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial – Alzheimer’s & Dementia

Commentary: Daily multivitamins improved the brain function of seniors in a trial — but plenty of questions remain – STAT

Cohort Study | Patients diagnosed with diabetes by oral glucose tolerance test without elevated HbA1c had similar cardiovascular and renal disease risks as those without diabetes.

15 Sep, 2022 | 13:12h | UTC

Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study – Circulation

Commentary: Patients diagnosed by OGTT without elevated HbA1c had similar CV, renal disease risks as those without diabetes – ACP Diabetes

Commentary on Twitter

#OriginalResearch: Oral glucose tolerance test diagnosed #diabetes were not confirmed by HbA1c during 4 year follow-up. Cases without HbA1c confirmation had similar vascular risk as the diabetes-free population. @whitehall2study @MikaKivimaki #AHAJournals https://t.co/ujC8cjRS7S pic.twitter.com/CRR3zlm5x2

— Circulation (@CircAHA) August 30, 2022

RCT | Effect of different itraconazole dosing regimens on cure rates, treatment duration, safety, and relapse rates in adult patients with tinea corporis/cruris.

15 Sep, 2022 | 13:10h | UTC

Effect of Different Itraconazole Dosing Regimens on Cure Rates, Treatment Duration, Safety, and Relapse Rates in Adult Patients With Tinea Corporis/Cruris: A Randomized Clinical Trial – JAMA Dermatology (free for a limited period)

Commentary on Twitter

Itraconazole is highly efficacious at all 3 doses but requires prolonged treatment, and a substantial number of patients relapsed after successful treatment. https://t.co/oOMkvp1WIp #Research pic.twitter.com/PoNYu50Cxr

— JAMA Dermatology (@JAMADerm) September 14, 2022

Cohort Study | Long-term outcomes among men undergoing active surveillance for prostate cancer.

15 Sep, 2022 | 13:11h | UTC

Long-term Outcomes Among Men Undergoing Active Surveillance for Prostate Cancer in Sweden – JAMA Network Open

Invited Commentary: Exploring the Long-term Outcomes of Active Surveillance Among Men With Prostate Cancer—Best for Whom? – JAMA Network Open

M-A | Role of pessaries in the treatment of pelvic organ prolapse.

15 Sep, 2022 | 13:08h | UTC

Role of Pessaries in the Treatment of Pelvic Organ Prolapse: A Systematic Review and Meta-analysis – Obstetrics & Gynecology (free for a limited period)

German guidelines on non-alcoholic fatty liver disease.

15 Sep, 2022 | 13:07h | UTC

Updated S2k Clinical Practice Guideline on Non-alcoholic Fatty Liver Disease (NAFLD) issued by the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie

AGA Clinical Practice Update | Diagnosis and management of nonalcoholic fatty liver disease in lean individuals.

Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group – The Lancet Gastroenterology & Hepatology (free registration required)

Nonalcoholic Fatty Liver Disease and Cardiovascular Risk: A Scientific Statement From the American Heart Association – Arteriosclerosis, Thrombosis, and Vascular Biology

Advancing the global public health agenda for NAFLD: a consensus statement – Nature Reviews Gastroenterology & Hepatology

Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease – Gastroenterology

Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports

Cohort Study | A 7-year study of the durability of improvements in pain, physical function, and work productivity after Roux-en-Y gastric bypass and sleeve gastrectomy.

15 Sep, 2022 | 13:03h | UTC

A 7-Year Study of the Durability of Improvements in Pain, Physical Function, and Work Productivity After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy – JAMA Network Open

News Release: Beyond weight loss: Improvements in pain, mobility persist long after bariatric surgery – University of Pittsburgh

Author Interview: Long-term Changes in Pain, Physical Function, and Work Productivity After Bariatric Surgery – JAMA

USPSTF Statement | The current evidence is insufficient to recommend routine screening for prediabetes and type 2 diabetes in children and adolescents.

14 Sep, 2022 | 13:23h | UTC

Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: US Preventive Services Task Force Recommendation Statement – JAMA

Editorials:

Recommendations for Screening Children and Adolescents for Prediabetes and Type 2 Diabetes – JAMA

Broader Screening for Youth-Onset Type 2 Diabetes—We Just Are Not There Yet – JAMA Network Open

Evidence Report: Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Patient Page: Screening for Type 2 Diabetes in Children and Adolescents – JAMA

Author Interview: USPSTF Recommendation: Screening for Prediabetes and Diabetes in Children and Adolescents – JAMA

Study | Vitamin D3 and omega-3 fatty acids not helpful in reducing the risk of frailty.

14 Sep, 2022 | 13:20h | UTC

News Release: Vitamin D3 and omega-3 fatty acids not helpful in reducing risk of frailty – Brigham and Women’s Hospital

Original Study: Effect of Vitamin D₃ and Omega-3 Fatty Acid Supplementation on Risk of Frailty: An Ancillary Study of a Randomized Clinical Trial – JAMA Network Open

Invited Commentary: There Is No Magic Pill to Prevent Frailty—You Still Have to Eat Your Vegetables – JAMA Network Open

Commentary on Twitter

New findings from the VITAL trial do not support the routine use of vitamin D3 or omega-3 fatty acid supplementation in community-dwelling older adults for the prevention of frailty. #OAResearch https://t.co/LIJO8bJ0Wk #OAResearch

— JAMA Network Open (@JAMANetworkOpen) September 13, 2022

Cohort Study | Risk factors for heart disease and stroke are largely similar in men and women globally.

14 Sep, 2022 | 13:18h | UTC

News Release: Risk factors for heart disease and stroke are largely similar in men and women globally, finds study – McMaster University

Original Study: Metabolic, behavioural, and psychosocial risk factors and cardiovascular disease in women compared with men in 21 high-income, middle-income, and low-income countries: an analysis of the PURE study – The Lancet (link to abstract – $ for full-text)

Commentary on Twitter

https://twitter.com/TheLancet/status/1569636002762817536

Cohort Study | Prospective associations of daily step counts and intensity with cancer and cardiovascular disease incidence and mortality and all-cause mortality.

14 Sep, 2022 | 13:17h | UTC

Prospective Associations of Daily Step Counts and Intensity With Cancer and Cardiovascular Disease Incidence and Mortality and All-Cause Mortality – JAMA Internal Medicine

Commentaries:

Higher Step Counts Equal Better CV Health: UK Biobank – TCTMD

Pace as important as 10,000 steps for health, finds new research – University of Sidney

How Many Steps a Day (and How Fast) to Lengthen Your Life? – HealthDay

Review | Multisystem inflammatory syndrome in children (MIS-C) and neonates (MIS-N) associated with COVID-19: optimizing definition and management.

14 Sep, 2022 | 13:15h | UTC

Multisystem inflammatory syndrome in children (MIS-C) and neonates (MIS-N) associated with COVID-19: optimizing definition and management – Pediatrics Research

Commentary on Twitter

Proposed classification of Multisystem inflammatory syndrome in #neonates (MIS-N)
Clinical features
Treatment and immunological mechanisms#MISC #covid19 #PIMSTS #PedsICU #NeoEBM @DrSBagci #NeoTwitter #Neonatology @DrKenRemy1 @ChrisCarrollMD @lizWWyld https://t.co/tDuM51GMr4 pic.twitter.com/PNobOOzevX

— Yonca Bulut M.D. (@yoncabulutmd) September 6, 2022