Family Medicine
UK National case series of group A streptococcus pleural empyema in children: clinical and microbiological features
15 Jan, 2023 | 20:24h | UTC
Commentary from the author on Twitter (thread – click for more)
huge amount of recent interest in invasive group A streptococcus (iGAS) infection in children
but up until now little patient-level clinical data on this spike in cases
we hope our case series @TheLancetInfDis will help address this knowledge gap https://t.co/75kV7FVmST 1/n pic.twitter.com/ytKyRu8MYi— Thomas Christie Williams (@Williams_T_C) January 10, 2023
SR | Baclofen for alcohol use disorder
15 Jan, 2023 | 20:11h | UTCBaclofen for alcohol use disorder – Cochrane Library
Summary: Baclofen for alcohol use disorder – Cochrane Library
UN Report | A child or youth died once every 4.4 seconds in 2021
13 Jan, 2023 | 13:46h | UTCNews Release: A child or youth died once every 4.4 seconds in 2021 – UN report – Word Health Organization
UN Reports:
Never Forgotten – The situation of stillbirth around the globe
Commentary on Twitter (thread – click for more)
The death of every child is an enormous tragedy.
In 2021:
♦️ 5 million children died before their 5th birthday
♦️ 2.1 million older children & young people lost their livesThat’s 1 loss every 4.4 seconds!
Most of these deaths were preventable with access to quality healthcare
— World Health Organization (WHO) (@WHO) January 10, 2023
Retrospective Study | Most patients with long Covid developed after mild infection get better within a year
13 Jan, 2023 | 13:42h | UTCLong covid outcomes at one year after mild SARS-CoV-2 infection: nationwide cohort study – The BMJ
News Release: Most long COVID effects resolve within a year after mild infection, finds study- British Medical Journal
Commentary: Long COVID After Mild Infection? It Fades Within a Year – HealthDay
Study identified six clusters of patients with long COVID, with distinct profiles of phenotypic abnormalities
13 Jan, 2023 | 13:40h | UTCGeneralisable long COVID subtypes: Findings from the NIH N3C and RECOVER programmes – eBioMedicine
SR | Dose-response effects of selective serotonin reuptake inhibitor monotherapy for the treatment of depression
13 Jan, 2023 | 13:37h | UTC
Commentary on Twitter
Read the latest #systematicreview of reviews and meta-narrative synthesis that looks at the dose efficiacy and tolerability of selective #serotonin reuptake inhibitors for #depression ▶️ https://t.co/B4lLe8YhcH pic.twitter.com/xIhz8sciJD
— BMJMedicine (@BMJMedicine) December 23, 2022
Development of telehealth principles and guidelines for older adults: a modified Delphi approach
13 Jan, 2023 | 13:32h | UTC
Report | Obstacles and opportunities in managing coexisting obesity and CKD
13 Jan, 2023 | 13:30h | UTC
Cohort Study | Antibiotic exposure linked to increased risk of inflammatory bowel disease
13 Jan, 2023 | 13:25h | UTCNews Release: Frequent use of antibiotics may heighten inflammatory bowel disease risk in over 40s – BMJ Newsroom
Commentaries:
Antibiotics may increase risk of inflammatory bowel disease, study finds – CIDRAP
Antibiotic Exposure Positively Linked to IBD Development – HealthDay
Commentary on Twitter
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al
"Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" viahttps://t.co/zc9bG3CpSm#GUTInTheNews pic.twitter.com/xra8wfEgnr
— Gut Journal (@Gut_BMJ) January 9, 2023
Study shows younger age at first acute otitis media and daycare attendance are the most important predictors for recurrence
13 Jan, 2023 | 13:22h | UTCWindow of Susceptibility to Acute Otitis Media Infection – Pediatrics
Invited commentary: Predicting Recurrent Acute Otitis Media and the Need for Tympanostomy: A Powerful Tool – Pediatrics
SR | Protein restriction for diabetic kidney disease
13 Jan, 2023 | 13:21h | UTCProtein restriction for diabetic kidney disease – Cochrane Library
Summary: Low protein diets for adults with diabetic kidney disease – Cochrane Library
RCT | A 24-week, all-oral regimen for rifampin-resistant tuberculosis
12 Jan, 2023 | 13:27h | UTCA 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis – New England Journal of Medicine
Commentary: Trial results show superiority of shorter, all-oral treatment for drug-resistant TB – CIDRAP
WHO consolidated guidelines on tuberculosis | Drug-resistant tuberculosis treatment, 2022 update
12 Jan, 2023 | 13:30h | UTCSee also:
– WHO consolidated guidelines on tuberculosis: module 1: prevention: tuberculosis preventive treatment
RCT | Early treatment with Molnupiravir did not reduce hospitalizations in high-risk adults with COVID-19
12 Jan, 2023 | 13:24h | UTCCommentaries:
Molnupiravir doesn’t cut Omicron hospitalization, death but can speed recovery – CIDRAP
Cohort Study | Risk factors for suffocation and unexplained causes of infant deaths
12 Jan, 2023 | 13:18h | UTCRisk Factors for Suffocation and Unexplained Causes of Infant Deaths – Pediatrics
Commentary: Risk Factors for Sleep-Related Suffocation, Infant Death Identified – HealthDay
Commentary on Twitter
In 2019, ~3,400 US families experienced the loss of an infant due to sudden death, including accidental suffocation in bed, SIDS, & unknown causes. This case-control study was initiated to improve understanding & inform prevention strategies: https://t.co/dlEGtapqDI #Pediatrics pic.twitter.com/IywHPXTohJ
— AAP Pediatrics (@aap_peds) December 5, 2022
RCT | Planned delivery for pre-eclampsia between 34 and 37 weeks of gestation
12 Jan, 2023 | 13:20h | UTCOriginal Publication: Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial – The Lancet
RCT | Effect of pessary vs. surgery in patients with symptomatic pelvic organ prolapse
12 Jan, 2023 | 13:16h | UTCEffect of Pessary vs Surgery on Patient-Reported Improvement in Patients With Symptomatic Pelvic Organ Prolapse: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Findings question value of pessary for pelvic organ prolapse – MDedge
Commentary on Twitter
In this study, among patients with symptomatic pelvic organ prolapse, an initial strategy of pessary therapy, compared with surgery, did not meet criteria for noninferiority with regard to patient-reported improvement at 24 months. https://t.co/PRb7iclR8O pic.twitter.com/ex3SSmLqyz
— JAMA (@JAMA_current) December 20, 2022
RCT | Second-line levofloxacin-based quadruple therapy vs. bismuth-based quadruple therapy for Helicobacter pylori eradication
12 Jan, 2023 | 13:06h | UTCSecond-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Liou et al – Second-line levofloxacin-based quadruple therapy vs bismuth-based quadruple therapy for H pylori eradication and long-term changes to the gut #microbiota and antibiotic resistome: an RCThttps://t.co/Aipu3TRyFr#Hpylori #microbiome #AMR @emadelomar pic.twitter.com/aeFMAI3FCj
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) December 20, 2022
M-A | Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy effects on obesity comorbidities
12 Jan, 2023 | 13:00h | UTC
M-A | The prevalence of obesity among children with type 2 DM
12 Jan, 2023 | 12:53h | UTCCommentary: Not All Pediatric Cases of Type 2 Diabetes Have Obesity – HealthDay
Commentary on Twitter
Meta-analysis finds that 75% of children with type 2 diabetes have obesity; not all pediatric T2DM patients have obesity. Further studies are needed to investigate the mechanisms beyond obesity driving this condition in children. https://t.co/RsDVSDq7rq
— JAMA Network Open (@JAMANetworkOpen) December 16, 2022
Statement | Pre-procedure and pre-admission COVID-19 testing no longer recommended for asymptomatic patients
11 Jan, 2023 | 14:36h | UTCRecommendation Statement: Asymptomatic screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) as an infection prevention measure in healthcare facilities: Challenges and considerations – Infection Control & Hospital Epidemiology
Commentary: Infectious disease board recommends hospitals stop screening asymptomatic patients for Covid-19 – STAT
Review | Autism spectrum disorder
11 Jan, 2023 | 14:31h | UTCAutism Spectrum Disorder: A Review – JAMA (free for a limited period)
Review | Durability of vaccine-induced and natural immunity against COVID-19
11 Jan, 2023 | 14:29h | UTC
Perspective | The limits of shared decision making
11 Jan, 2023 | 14:28h | UTCThe limits of shared decision making – BMJ Evidence-Based Medicine
RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis
11 Jan, 2023 | 14:27h | UTCDupilumab in Adults and Adolescents with Eosinophilic Esophagitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Weekly Dupilumab Beneficial in Eosinophilic Esophagitis – HealthDay