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Family Medicine

Screening for Endocrine Hypertension

14 Apr, 2017 | 16:27h | UTC

Screening for Endocrine Hypertension: An Endocrine Society Scientific Statement (free)

Source: Screen for Endocrine Hypertension, Endocrine Society Says – Medscape (free registration required)

“The statement provides guidance on screening for 15 hormonal disorders that present with hypertension and that can be potentially cured with surgery or treated with medication” (from Medscape commentary above).

 


Screening to Prevent Invasive Cervical Cancer Guideline

13 Apr, 2017 | 16:03h | UTC

Screening to Prevent Invasive Cervical Cancer: ASCO Resource-Stratified Clinical Practice Guideline (free)

“The ASCO guidelines outline the minimum standards for HPV-based screening for each resource strata; additional and more frequent screening may be added as the resources become available”.

 


Prostate Cancer Screening – Conflicting views on the new USPSTF draft recommendations

13 Apr, 2017 | 16:06h | UTC

Prostate Cancer Screening – Conflicting views on the new USPSTF draft recommendations

In favor of screening: New Official Prostate Cancer Screening Guidelines Announced: Too Little, Too Late? – Forbes (free) AND Federal Task Force Softens Opposition To Routine Prostate Cancer Screening – NPR

Against screening: The new recommendations for prostate cancer screenings are a bad deal – STAT News (free)

See also: Original USPSTF draft recommendations and related commentaries in yesterday’s issue

 


Short term use of oral corticosteroids and related harms

13 Apr, 2017 | 16:07h | UTC

Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study – The BMJ (free)

Corticosteroids, even if used for short periods of time, seems to be associated with significant morbidity and mortality. In this retrospective cohort with 1.5 million adults, the incidence of acute adverse events (sepsis, venous thromboembolism, fracture) increased by twofold to fivefold above background rates.

 


Prostate Cancer Screening Draft Recommendations – USPSTF

12 Apr, 2017 | 15:58h | UTC

Prostate Cancer Screening Draft Recommendations – U.S. Preventive Services Task Force (free)

Viewpoint: The US Preventive Services Task Force 2017 Draft Recommendation Statement on Screening for Prostate Cancer: An Invitation to Review and Comment – JAMA (free)

See also: Should you get screened for prostate cancer? We break down the latest advice – STAT News (free)

For those aged 55 to 69 it recommends “informed, individualized decision making based on a man’s values and preferences”. According to a useful infographic from the draft recommendations, the benefits are likely small. For every 1000 men offered PSA based screening over a period of 10-15 years, the test would avoid cancer spreading in 3 men and death from prostate cancer in 1-2 men, with the undesired consequences of false positives and subsequent procedures in many patients.

 


Management of Osteoarthritis of the Hip

12 Apr, 2017 | 15:55h | UTC

Management of Osteoarthritis of the Hip – American Academy of Orthopedic Surgeons (free PDF)

Source: AAOS releases new clinical practice guideline for osteoarthritis of the hip – Medical Express (free)

 


How Many Pills Are Too Many?

12 Apr, 2017 | 15:56h | UTC

How Many Pills Are Too Many? – The New York Times (10 articles per month are free)

“Evidence has mounted about the dangers of taking multiple, perhaps unnecessary, medications” (from Tweet)

 


Respiratory effect of beta-blockers in people with asthma and cardiovascular disease

11 Apr, 2017 | 15:48h | UTC

Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study – BMC Medicine (free) (RT @atscommunity)

Cardioselective beta-blockers, mostly atenolol and bisoprolol in this cohort, were not associated with increased risk of moderate or severe asthma exacerbations. In contrast, non-selective beta-blockers, mostly sotalol and carvedilol in this cohort, were associated with increased risk.

 


EULAR revised recommendations for the management of fibromyalgia

12 Apr, 2017 | 15:52h | UTC

EULAR revised recommendations for the management of fibromyalgia – Annals of Rheumatic Diseases (free)

Source: EULAR Revised Recommendations for the Management of Fibromyalgia – Medscape (free registration required)

 


Why Are So Many People Popping Vitamin D?

11 Apr, 2017 | 15:47h | UTC

Why Are So Many People Popping Vitamin D? – The New York Times (10 articles per month are free)

“Labs performing these tests are reporting perfectly normal levels of vitamin D — 20 to 30 nanograms per milliliter of blood — as “insufficient.” As a consequence, millions of healthy people think they have a deficiency”

Note: Some organizations still think appropriate levels would be above 30 nanograms per milliliter of blood, more details in the text.

 


Multivitamins are probably a waste of money

12 Apr, 2017 | 15:50h | UTC

Vitamins and the Failure of Free-Market Health – The Atlantic (free)

“The booming dietary-supplement industry is plagued by outlandish claims, undermining credible science, and seeding confusion”.

 

Effect of Baseline Nutritional Status on Long-term Multivitamin Use and Cardiovascular Disease Risk – JAMA Cardiology (link to abstract – $ required for full-text)

See also: Multivitamins may not improve heart health in men – UPI (free) AND Other recent commentary on multivitamins: Multivitamins a waste of money and just create ‘very expensive urine’ – The Guardian (free)

“Multivitamin use does not prevent major CV disease events in men, regardless of baseline nutritional status” (RT @CaulfieldTim)

 


Hypertension Canada’s 2017 Guidelines

10 Apr, 2017 | 16:10h | UTC

Hypertension Canada’s 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults (free)

 


F.D.A. Will Allow 23andMe to Sell Genetic Tests for Disease Risk to Consumers

10 Apr, 2017 | 16:03h | UTC

F.D.A. Will Allow 23andMe to Sell Genetic Tests for Disease Risk to Consumers – The New York Times (10 articles per month are free)

See also: Before you send your spit to 23andMe, what you need to know – STAT News (free) AND 23andMe given green light to sell DNA tests for 10 diseases – Nature News (free) AND 23andMe Rides Again: FDA Clears Genetic Tests To Predict Disease Risk – Forbes (free) AND Too Much Information? FDA Clears 23AndMe to Sell Home Genetic Tests for Alzheimer’s and Parkinson’s – Scientific American (free)

“The controversial step will significantly expand direct-to-consumer testing – but what if the news is bad?” (from Scientific American above)

 


Achieved blood pressure and cardiovascular outcomes in high-risk patients

11 Apr, 2017 | 15:44h | UTC

 

Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials – The Lancet (link to abstract – $ required for full-text) (RT @AnilMakam “Lower achieved blood pressure in high risk patients for cardiovascular disease do WORSE” see Tweets)

In high-risk patients, patients who achieved a systolic blood pressure < 120 mmHg or a diastolic blood pressure < 70 mmHg had HIGHER risk of complications. “These data suggest that the lowest blood pressure possible is not necessarily the optimal target for high-risk patients”

 


Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients

10 Apr, 2017 | 16:08h | UTC

Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients – New England Journal of Medicine (link to abstract – $ required for full text)

Quick Take Video Summary: SURTAVI Study: TAVR versus Open Surgery (free)

See this and other highlights from the American College of Cardiology’s 66th Annual Scientific Session (some articles are no longer free)

This innovative technology seems to be useful for patients with aortic stenosis at high risk for surgery. In this new study, it was noninferior to surgery at 2 years of follow-up in old patients (averaged nearly 80 years) at intermediate risk. Longer follow up data will be important to see if it is a suitable alternative for younger patients.

 


Here’s why one tech investor thinks some doctors will be ‘obsolete’ in five years

10 Apr, 2017 | 15:56h | UTC

Here’s why one tech investor thinks some doctors will be ‘obsolete’ in five years – CNBC (free) (RT @CMichaelGibson)

According to this point of view, radiologists will be the first ones that are affected by Artificial Intelligence. As we can see below, other specialists that work by interpreting medical images may follow, like dermatologists, ophthalmologists and pathologists.

See also: If You Look at X-Rays or Moles for a Living, AI Is Coming for Your Job – Wired (free) AND Adapting to Artificial Intelligence: Radiologists and Pathologists as Information Specialists – JAMA Viewpoint (free – and legal – PDF found with Unpaywall) AND Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA Internal Medicine (link to abstract – $ required for full-text) AND Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features – Nature(free) see commentary in Computers trounce pathologists in predicting lung cancer type, severity, researchers find – Science News (free)

 


Screening for Adult Attention-Deficit/Hyperactivity Disorder?

10 Apr, 2017 | 16:05h | UTC

The World Health Organization Adult Attention-Deficit/Hyperactivity Disorder Self-Report Screening Scale for DSM-5 – JAMA Psychiatry (free)

Invited commentary: Good News for Screening for Adult Attention-Deficit/Hyperactivity Disorder – JAMA Psychiatry (free)

See also: Do You Zone Out? Procrastinate? Might Be Adult ADHD – NPR Health News (free)

Others disagree… call it “disease mongering”, “overdiagnosis”. For example, Prof Allen Francis, author of Saving Normal: An Insider’s Revolt against Out-of-Control Psychiatric Diagnosis, DSM-5, Big Pharma, and the Medicalization of Ordinary Life, wrote some remarks about the study, see Tweet 1Tweet 2 and Tweet 3

See also: The Selling of Attention Deficit Disorder – The New York Times (10 articles per month are free)

 


TV. How much is too much for our kids?

10 Apr, 2017 | 16:01h | UTC

TV. How much is too much for our kids? – World Economic Forum (free)

Original Article Abstract ($ required for full-text): Family Socioeconomic Status Moderates Associations Between Television Viewing and School Readiness Skills – Journal of developmental and behavioral pediatrics

See also: Media and Young Minds – Recommendations from The American Academy of Pediatrics (free) AND Pediatricians relax guidelines on screen time for kids to give more flexibility – STAT News (free)

 


Seniors are given so many drugs, it’s madness

10 Apr, 2017 | 15:54h | UTC

Seniors are given so many drugs, it’s madness – The Globe and Mail (free) (RT @RasoiniR)

“While most prescribing is well-intentioned, it’s also unco-ordinated; there is a tendency to overmedicate and leave people on drugs for too long”.

 


Antipsychotics May Boost Respiratory Failure Risk in COPD – MedPage Today

7 Apr, 2017 | 15:50h | UTC

Association Between Antipsychotic Agents and Risk of Acute Respiratory Failure in Patients With Chronic Obstructive Pulmonary Disease – JAMA Psychiatry (Link to abstract – $ required for full-text) (RT @atscommunity)

See also: Antipsychotics Tied to Respiratory Failure in At-Risk Patients – Medscape (free registration required) AND Antipsychotics May Boost Respiratory Failure Risk in COPD – MedPage Today (free registration required)

 


Benefits of Endovascular Treatment for Stroke Last at Least 2 Years

7 Apr, 2017 | 15:51h | UTC

Benefits of Endovascular Treatment for Stroke Last at Least 2 Years – Physician’s First Watch (free)

Original article abstract ($ required for full-text): Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke – New England Journal of Medicine

 


No TV during meals may lower obesity risk

10 Apr, 2017 | 16:00h | UTC

No TV during meals may lower obesity risk – Medical News Today (free)

Original article abstract ($ required for full-text): Television, Home-Cooked Meals, and Family Meal Frequency: Associations with Adult Obesity – Journal of the Academy of Nutrition and Dietetics

Related article: Screen time is associated with adiposity and insulin resistance in children – Archives of Diseases in Childhood (free) AND Screentime linked to greater diabetes risk among children – The Guardian (free)

The first study in adults and the second study in children suggest there might be a link between screen time and weight gain or adiposity.

 


Smoking causes one in ten deaths globally, major new study reveals

7 Apr, 2017 | 15:52h | UTC

Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the Global Burden of Disease Study 2015 – The Lancet (free)

Related commentary: Death, disease, and tobacco (free)

Explore data visualizations by The Institute for Health Metrics and Evaluation (IHME) (free)

See also: Smoking causes one in ten deaths globally, major new study reveals – The Guardian (free)

See also: Other articles from The Global Burden of Diseases Study (free)

 


With same training, insulin pumps no better than injections

7 Apr, 2017 | 15:26h | UTC

Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE) – The BMJ (free)

Source: With same training, insulin pumps no better than injections – Reuters Health News (free) (RT @CMichaelGibson)

 


Are Virtual Doctor Visits Really Cost-Effective?

7 Apr, 2017 | 15:28h | UTC

Are Virtual Doctor Visits Really Cost-Effective? Not So Much, Study Says – Kaiser Health News (free)

“Perhaps telehealth visits don’t save money after all. Increased convenience can increase utilization” (RT @drval)

 


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