Family Medicine
Countering cognitive biases in minimizing low value care
12 May, 2017 | 19:34h | UTCReview: Countering cognitive biases in minimizing low value care – The Medical Journal of Australia (free)
“How cognitive bias affects clinical decision making and what to do about it. Well written & useful” (RT @carissa_bon and @JulieLeask see Tweet)
Arthroscopic surgery for degenerative knee arthritis and meniscal tears: a clinical practice guideline
12 May, 2017 | 19:38h | UTCCommentaries: This orthopedic surgery is the world’s most common. But patients rarely benefit, a panel says – STAT News (free) AND Guideline Recommends Against Arthroscopy for Most Cases of Degenerative Knee Disease – Journal Watch (free) AND Arthroscopic Surgery Doesn’t Help With Arthritis Knee Pain – NPR Health News (free)
Socioeconomic status as an effect modifier of alcohol consumption and harm
12 May, 2017 | 19:29h | UTCInvited commentary: Socioeconomic status and susceptibility to alcohol-related harm (free)
Commentary: Poorest at greater risk from heavy drinking, says study – BBC (free)
Internet-Based Vestibular Rehabilitation for Older Adults With Chronic Dizziness
12 May, 2017 | 19:36h | UTCSee also: Balance retraining tool used in the study (free)
Commentaries: Online Rehabilitation Program Reduces Chronic Dizziness – Medscape (free registration required) AND Online Intervention Could Reduce Chronic Dizziness – Physician’s First Watch (free)
Drug-Eluting Stents Versus Coronary Artery Bypass Grafting in Unprotected Left Main Coronary Narrowing
11 May, 2017 | 18:37h | UTCMeta-Analysis of Drug-Eluting Stents Versus Coronary Artery Bypass Grafting in Unprotected Left Main Coronary Narrowing – Journal of The American College of Cardiology (link to abstract – $ for full-text) (source: EvidenceAlerts)
Related recent meta-analysis: Percutaneous Coronary Intervention Using Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Stenosis: A Meta-Analysis of Randomized Trials – Circulation: Cardiovascular Interventions (free) AND Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis – BMC Medicine (free)
PCI with drug-eluding stents seems to be a safe alternative to CABG in Unprotected Left Main Coronary Artery Stenosis, but it is associated with higher rates of repeat revascularization.
Risk of acute myocardial infarction with NSAIDs
11 May, 2017 | 18:38h | UTCCommentaries: Meta-Analysis: Just a Week of NSAID Use Tied to Increased Heart Attack Risk – Journal Watch (free) AND Common painkillers linked to increased risk of heart attack, study says – CNN (free) All NSAIDs Linked to Increased MI Risk – Medscape (free registration required)
Another study suggesting NSAIDs may be associated with increased cardiovascular risk.
Ten Principles of Good Prescribing
11 May, 2017 | 18:42h | UTCTen Principles of Good Prescribing – by J K Aronson, Centre for Evidence-Based Medicine (CEBM) (free)
Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality
10 May, 2017 | 18:27h | UTCMeta-analysis: Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies – European Journal of Epidemiology (free)
Source: Eating cheese does not raise risk of heart attack or stroke, study finds – The Guardian (free)
Dairy seems to be neutral regarding risks of cardiovascular diseases and all-cause mortality.
Mortality from different causes associated with meat, heme iron, nitrates, and nitrites
10 May, 2017 | 18:28h | UTCMeta-analysis: Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study – The BMJ (free)
High intakes of red and processed meat are associated with increased risks of all-cause mortality and death due to nine different causes.
Screening for Thyroid Cancer: USPSTF Recommendation Statement
10 May, 2017 | 18:29h | UTCScreening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Editorial 1: The USPSTF Recommendation on Thyroid Cancer Screening: Don’t “Check Your Neck” (free)
Editorial 2: Cancer Screening, Overdiagnosis, and Regulatory Capture (free)
Editorial 3: How to Look for Thyroid Cancer (free)
Commentaries: No Symptoms, No Thyroid Screening, Says USPSTF – Medscape (free registration required) AND Don’t Screen For Thyroid Cancer, Task Force Says – NPR Health News (free) AND USPSTF Says No to Thyroid Cancer Screening – MedPage Today (free registration required)
The USPSTF recommended against screening for thyroid cancer in asymptomatic adults with “grade D” recommendation (Grade D = “The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits”).
Guideline for opioid therapy and chronic noncancer pain
10 May, 2017 | 18:26h | UTCGuideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free) (RT @IrfanDhalla and @jendlake see Tweet)
Approach to the Patient with Hematochezia
9 May, 2017 | 20:43h | UTCReview: Approach to the Patient with Hematochezia – Mayo Clinic Proceedings (free) (RT @HMVJC)
Noncommunicable diseases: the slow-motion disaster
9 May, 2017 | 18:21h | UTCNoncommunicable diseases: the slow-motion disaster – World Health Organization (free)
Related WHO resources: Other dimensions of the NCD crisis: from mental health, ageing, dementia and malnutrition to deaths on the roads, violence and disability (free) AND Tools for implementing WHO PEN (Package of essential noncommunicable disease interventions) (free) AND WHO’s work on NCDs (free)
Source: Noncommunicable Diseases: A Global ‘Slow-Motion Disaster’ – Medscape (free registration required)
Type 2 diabetes in adults: management – NICE Guideline
9 May, 2017 | 20:44h | UTC
Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes
9 May, 2017 | 18:17h | UTCReview: Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes – Circulation Research (free)
Fever of unknown origin (FUO) revised
9 May, 2017 | 20:42h | UTCReview: Fever of unknown origin (FUO) revised – Wiener klinische Wochenschrift (free) (RT @HMVJC)
New Osteoporosis Guidelines from ACP
9 May, 2017 | 18:19h | UTCCommentaries: ACP Updates Guidelines on Treating Low Bone Density, Osteoporosis – Physician’s First Watch (free) AND New ACP Guidelines on the Treatment of Osteoporosis – Medscape (free registration required)
Related guideline: UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis (free)
Reducing inappropriate prescribing easier said than done
6 May, 2017 | 20:37h | UTCReducing inappropriate prescribing easier said than done – CMAJ News (free)
Related: Canadian Deprescribing Network (CaDeN) (free)
AND CaDeN Deprescribing Guidelines and Algorithms (free) AND Deprescribing guidelines for the elderly – Ontario Pharmacy Evidence Network(free)
Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images
6 May, 2017 | 20:34h | UTCSource: Management of Pulmonary Nodules Found Incidentally on Computed Tomography Scans – Journal Watch (free)
Incidental pulmonary nodules discovered outside the context of screening or cancer follow-up are increasingly common in clinical practice. The purpose of these updated recommendations is to reduce the number of unnecessary follow-up examinations while providing practical guidance on follow-up intervals for selected larger nodules.
Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today
6 May, 2017 | 20:39h | UTCResearch letter: Applicability of the IMPROVE-IT Trial to Current Patients With Acute Coronary Syndrome – JAMA Internal Medicine (link to abstract – $ for full text)
Source: Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today (free registration required)
Related: Exclusion of patients with concomitant chronic conditions in ongoing randomised controlled trials targeting 10 common chronic conditions and registered at ClinicalTrials.gov: a systematic review of registration details – BMJ Open (free) AND Do cancer clinical trials exaggerate the real-world benefits of drugs? – STAT News (free)
Patients in clinical trials are often younger, healthier (with less comorbidities), better plugged in to the health care system, better educated and wealthier, indicating that the external validity or generalizability of much of the current evidence to real-world settings may be relatively weak.
USPSTF recommendations: A 2017 roundup
6 May, 2017 | 20:36h | UTCUSPSTF recommendations: A 2017 roundup – Journal of Family Practice
Multiple-micronutrient supplementation for women during pregnancy
5 May, 2017 | 20:26h | UTCMultiple-micronutrient supplementation for women during pregnancy – Cochrane Library (free summary – $ for full-text)
See also a recent landmark study on the subject in our March 27th issue, see #9.
Source: EvidenceAlerts
The findings of this systematic review support the effect of Multiple-micronutrient supplements with iron and folic acid in improving some birth outcomes.
Association Between Academic Medical Center Pharmaceutical Detailing Policies and Physician Prescribing
4 May, 2017 | 20:14h | UTCAssociation Between Academic Medical Center Pharmaceutical Detailing Policies and Physician Prescribing – JAMA (link to abstract – $ for full-text)
Commentaries: Doctors Prescribe More Generics When Drug Reps Are Kept At Bay – NPR (free) AND Limiting Interactions with Pharma Reps Cuts Brand Name Drug Prescriptions – Physician’s First Watch (free)
Alternate-day fasting does not seem to lead to greater weight loss
3 May, 2017 | 17:26h | UTCCommentaries: Fasting Studies Clash With Our Desire To Eat What We Want, When We Want It – NPR Health News (free) AND Fasting Every Other Day Does Not Lead to Greater Weight Loss – Physician’s First Watch (free) AND Same Weight Loss With Alternate-Day Fasting vs Cutting Calories – Medscape (free registration required) AND Alternate-Day Fasting Doesn’t Lead to Speedier Weight Loss – MedPage Today (free registration required)
Randomized trial with 100 patients showed no difference in weight loss between alternate-day fasting versus calorie restriction.
Urinary catheter care: what does the evidence say?
4 May, 2017 | 20:12h | UTCUrinary catheter care: what does the evidence say? – Cochrane Library (free)
“How frequently should indwelling urinary catheters be changed? Are catheter washouts effective? Which type of catheter reduces rates of urinary tract infection?”. This post look at the evidence regarding urinary catheter care.