Family Medicine
Timing of food introduction and development of food sensitization
12 Jun, 2017 | 19:53h | UTCTiming of food introduction and development of food sensitization in a prospective birth cohort – Pediatric Allergy and Immunology (link to abstract – $ for full-text)
Commentary: Delayed food introduction may increase likelihood of allergy in later childhood – McMaster University, via News Medical (free)
Working while sick
12 Jun, 2017 | 19:50h | UTCWorking with influenza-like illness: Presenteeism among US health care personnel during the 2014-2015 influenza season – American Journal of Infection Control (link to abstract – $ for full-text)
Commentaries: Working while sick – ACP Internist (free) AND Health worker survey reveals many work during flu illness – CIDRAP (free)
Over 40% of surveyed health care personnel worked with self-reported influenza-like illness. “To reduce levels of health-worker–associated flu transmission, the researchers said that misconceptions about working while sick and sick leave policies both need to be addressed” (from CIDRAP)
Lower Risk of Heart Failure and Death in Patients Initiated on SGLT-2 Inhibitors?
12 Jun, 2017 | 19:52h | UTCCommentaries: Risk of HF and Death in Patients on SGLT-2 Inhibitors – American College of Cardiology, Latest in Cardiology (free) AND SGLT2 inhibitors may have class effect for reduction of cardiac risk – ACP Diabetes Monthly (free)
Observational data suggests these class of drugs may be associated with lower risk of heart failure and deaths compared to other drugs.
Canagliflozin will receive new boxed warning about amputation risks
12 Jun, 2017 | 19:51h | UTCCanagliflozin will receive new boxed warning about amputation risks – ACP Internist (free)
FDA Drug Safety Communication: FDA confirms increased risk of leg and foot amputations with the diabetes medicine canagliflozin (Invokana, Invokamet, Invokamet XR) (free)
Gastroesophageal Reflux Disease Guideline
12 Jun, 2017 | 19:47h | UTC
Head injury: assessment and early management
9 Jun, 2017 | 16:07h | UTCHead injury: assessment and early management – NICE Guideline (free)
Prevention and Treatment of Glucocorticoid-Induced Osteoporosis
9 Jun, 2017 | 16:04h | UTCCommentary: ACR Releases Guideline on prevention & treatment of glucocorticoid-induced osteoporosis – American College of Rheumatology, via EurekAlert (free)
Risk of Diabetic Ketoacidosis after Initiation of an SGLT2 Inhibitor
9 Jun, 2017 | 16:02h | UTCCommentaries: Study Warns of Diabetic Ketoacidosis With SGLT2 Inhibitors in T2D – MedPage Today (free registration required) AND SGLT2 Inhibitors Double the Risk for Diabetic Ketoacidosis – Medscape (free registration required) AND New class of type 2 diabetes drug associated with rare, life-threatening outcome – Brigham and Women’s Hospital, Via EurekAlert (free)
Related: SGLT2 inhibitors and diabetic ketoacidosis: data from the FDA Adverse Event Reporting System – Diabetologia (link to abstract – $ for full-text)
Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline
8 Jun, 2017 | 15:58h | UTCEditorial: Alcohol consumption and brain health (free)
Commentaries: Even moderate drinking linked to a decline in brain health, finds study – Oxford’s Department of Psychiatry (free) AND Moderate drinking may alter brain, study says – CNN (free) AND Even moderate drinking may speed brain decline – STAT News (free) AND Even moderate drinking linked to changes in brain structure, study finds – Reuters (free)
Serum uric acid levels and multiple health outcomes
8 Jun, 2017 | 15:57h | UTCObservational studies suggest that high serum uric acid levels are associated with multiple health outcomes, including cardiovascular and metabolic diseases. This review findings suggest there is a clear association only for gout and nephrolithiasis.
Practice Guidelines for Preoperative Fasting
9 Jun, 2017 | 16:03h | UTCPractice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration – Anesthesiology, via Medscape (free registration required)
Management of polypharmacy
8 Jun, 2017 | 15:52h | UTCCurrent and future perspectives on the management of polypharmacy – BMC Family Practice (free) (RT @Azeem_Majeed see Tweet)
Can Personalized Care Planning Improve Primary Care?
8 Jun, 2017 | 15:45h | UTCViewpoint: Can Personalized Care Planning Improve Primary Care? – JAMA (free)
Related: Multimorbidity: clinical assessment and management – NICE Guideline (free)
See more on caring for people with Complex Needs in our April 24th issue (see #4),
Eggs in Early Complementary Feeding and Child Growth
8 Jun, 2017 | 15:48h | UTCEggs in Early Complementary Feeding and Child Growth: A Randomized Controlled Trial – Pediatrics (link to abstract – $ for full-text)
Commentary: Eggs Significantly Increase Growth in Young Children – Washington University in St. Louis, via NewsWise (free) AND An egg a day appears to help young children grow taller – BBC Health News (free)
“Surpassing previous research, study finds eggs are more viable nutrition, better intervention for children in developing countries” (from NewsWise)
Pelvic floor exercises may reduce need for further treatments for pelvic organ prolapse
8 Jun, 2017 | 15:49h | UTCPelvic floor exercises may reduce need for further treatments for pelvic organ prolapse – NIHR Signal (free)
Original article: Pelvic floor muscle training for secondary prevention of pelvic organ prolapse (PREVPROL): a multicentre randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Association of Gestational Weight Gain With Maternal and Infant Outcomes
8 Jun, 2017 | 15:50h | UTCAssociation of Gestational Weight Gain With Maternal and Infant Outcomes: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: RCOG statement on gestational weight gain or loss and adverse outcomes – Royal College of Obstetricians and Gynaecologists(free) AND Weight gain greater, less than recommended during pregnancy linked with increased risk of adverse outcomes – The JAMA Network Journals, via EurekAlert (free) AND Pregnancy Weight Gain Status Tied to Adverse Outcomes – MedPage Today (free registration required) AND Gaining Too Much, Too Little Weight in Pregnancy Tied to Adverse Outcomes for Mother, Baby – Physician’s First Watch (free) AND Global study finds 75% of pregnant women don’t have healthy weight gain – The Guardian (free)
Pharmacologic Management of Newly Detected Atrial Fibrillation
7 Jun, 2017 | 15:25h | UTCKey Recommendations: Pharmacologic Management of Newly Detected Atrial Fibrillation (free)
Short-term catheterisation: considerations for best practice
8 Jun, 2017 | 15:42h | UTC
Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (again)
7 Jun, 2017 | 15:21h | UTCAntibiotics Versus Surgical Therapy for Uncomplicated Appendicitis: Systematic Review and Meta-analysis of Controlled Trials – Annals of Surgery (link to abstract – $ for full-text)
Commentary: Antibiotics Versus Surgery: Equally Effective in Treating Appendicitis? – Medscape (free registration required)
This meta-analysis and the author’s conclusions do not favor antibiotics alone for the treatment of uncomplicated appendicitis, contradiction the results of other recent meta-analysis, as well as a recent guideline on the subject, suggesting antibiotics might be an option in selected cases.
Inflammatory bowel disease: Five things physicians and patients should question
7 Jun, 2017 | 15:19h | UTC
Association Between Cirrhosis and Stroke
7 Jun, 2017 | 15:18h | UTCAssociation Between Cirrhosis and Stroke in a Nationally Representative Cohort – JAMA Neurology (free)
Commentary: Cirrhosis Tied to Stroke Risk- Physician’s First Watch (free)
Patients with cirrhosis seem to have a higher risk of stroke, particularly hemorrhagic stroke.
BSACI guideline for the diagnosis and management of peanut and tree nut allergy
7 Jun, 2017 | 15:20h | UTCEditorial: Nut allergy guideline (free)
Commentary: First ever single guidance published for investigating and managing nut allergy – EurekAlert (free)
See also related guidelines (U.S.) and commentaries recommending early introduction of peanuts to prevent allergies in our January 6 issue, see #1 and #2.
What is the best antidote for a jellyfish sting?
7 Jun, 2017 | 15:08h | UTCCommentary: What is the best antidote for a jellyfish sting? (Clue: it’s not urine) – The Guardian (free)
Vinegar seems to be the best treatment.
Growth and Rupture Risk of Small Unruptured Intracranial Aneurysms
7 Jun, 2017 | 15:11h | UTCGrowth and Rupture Risk of Small Unruptured Intracranial Aneurysms: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Growth, rupture risk appear low for small intracranial aneurysms, review indicates – ACP Internist Weekly (free) AND How Frequently Do Small Brain Aneurysms Rupture? – MedPage Today (free registration required)
“The annualized rupture rate was 0% for aneurysms 3 mm or smaller, below 0.5% for aneurysms 5 mm or smaller, and below 1% for aneurysms 7 mm or smaller”
Home blood pressure monitors inaccurate 70 percent of the time?
7 Jun, 2017 | 15:02h | UTCCommentaries: Home blood pressure monitors inaccurate 70 percent of the time, study finds – MedicalXpress (free) AND Home blood pressure monitors may not be accurate enough – Reuters Health (free)
Small study (85 patients) suggests many of the devices are too inaccurate to be useful.