Family Medicine
Review: Organ dysfunction, injury and failure in acute heart failure
24 Jul, 2017 | 01:02h | UTC
Why are doctors plagued by depression and suicide?
25 Jul, 2017 | 00:09h | UTCWhy are doctors plagued by depression and suicide? A crisis comes into focus – STAT News (free)
Related: Protecting interns and other physicians from depression and suicide – STAT News (free)
Effects of NOACs Versus Warfarin in Patients With AF and Valvular Heart Disease
24 Jul, 2017 | 00:58h | UTC“Among patients with AF and native VHD, NOACs reduce stroke and systemic embolism compared with warfarin”.
Fluoroquinolone restriction to control fluoroquinolone-resistant Clostridium difficile
24 Jul, 2017 | 01:01h | UTCInvited Commentary: Fluoroquinolone restriction to control fluoroquinolone-resistant Clostridium difficile (free)
“Very important finding! Restricting fluoroquinolones more important than infection control measures to prevent CDI” (RT @sanjaysaint see Tweet)
High prevalence of erectile dysfunction in diabetes
24 Jul, 2017 | 00:56h | UTCHigh prevalence of erectile dysfunction in diabetes: a systematic review and meta-analysis of 145 studies – Diabetic Medicine (link to abstract – $ for full-text)
Commentary: Screening for Erectile Dysfunction Should Be Routine in Diabetes – Medscape (free registration required)
“Erectile dysfunction 3.5 times more common in diabetes” (RT @kamleshkhunti see Tweet)
Diabetic retinopathy: current understanding, mechanisms, and treatment strategies
24 Jul, 2017 | 00:55h | UTCDiabetic retinopathy: current understanding, mechanisms, and treatment strategies – JCI Insight (free)
“It affects 100 M people WW, but under-diagnosed/treated: excellent review of diabetes retinopathy” (RT @EricTopol see Tweet)
Free Online Course: Understanding Obesity
24 Jul, 2017 | 00:24h | UTCStarts Today! Free Online Course: Understanding Obesity – The University of Edinburgh and Coursera
High-Dose Vitamin D Doesn’t Prevent Viral Upper Respiratory Tract Infections in Children
23 Jul, 2017 | 22:47h | UTCEffect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy Children – JAMA (link to abstract – $ for full-text)
Commentaries: High-Dose Vitamin D Does Not Prevent Kids’ Colds in Winter – Medscape (free registration required) AND High-dose vitamin D ‘doesn’t prevent colds and flu in kids’ – NHS Choices (free)
Emerging Data Show E-Cigarettes May Pose Heart Risk
23 Jul, 2017 | 16:52h | UTCEmerging Data Show E-Cigarettes May Pose Heart Risk – Circulation (free)
Cognitive Impairment and Heart Failure
23 Jul, 2017 | 16:04h | UTCCognitive Impairment and Heart Failure: Systematic Review and Meta-Analysis – Journal of Cardiac Failure (link to abstract – $ for full-text)
Commentary: Cognitive Impairment and HF – American College of Cardiology, Latest in Cardiology (free)
Guidelines for the diagnosis and therapy of chronic pancreatitis
23 Jul, 2017 | 14:32h | UTCSource: Guidelines: 2017 Midyear Review – Medscape (free registration required)
Reviews on thrombosis and hemostasis
23 Jul, 2017 | 13:53h | UTCSelection of state-of-the-art open access reviews on thrombosis and hemostasis, celebrating the 60th anniversary of the Journal – Thrombosis and Haemostasis (free PDF Articles)
– Homepage
– Editorial: Thrombosis and Haemostasis: Past, present and future
– Venous thromboembolism: Past, present and future
– Stroke prevention in atrial fibrillation: Past, present and future
– Antithrombotic therapy for acute coronary syndrome: Past, present and future
– Therapeutic strategies for atherosclerosis and atherothrombosis: Past, present and future
– NOACs for treatment of venous thromboembolism in clinical practice
– The management of acute venous thromboembolism in clinical practice
Source: Critical Care Reviews Topic of The Week
Maternal intake of sugar during pregnancy and childhood respiratory and atopic outcomes
22 Jul, 2017 | 22:25h | UTCCommentaries: Sugar intake during pregnancy is associated with allergy and allergic asthma in children – Queen Mary University of London Science Daily (free) AND Mom’s sweet tooth may be linked to child’s allergies, study says – CNN (free) AND Eating Sugar During Pregnancy Is Linked to Kids’ Allergies – TIME (free)
Observational study suggests maternal intake of sugar during pregnancy may increase allergic problems in offspring.
Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis
23 Jul, 2017 | 13:22h | UTCSource: ACP Journal Wise ($)
“A national screening programme for atrial fibrillation is likely to represent a cost-effective use of resources, with systematic opportunistic screening more likely to be cost-effective than systematic population screening”
Workplace Factors Associated With Burnout of Family Physicians
22 Jul, 2017 | 21:47h | UTCWorkplace Factors Associated With Burnout of Family Physicians – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Workplace Factors Contribute to Burnout in Family Physicians – Medscape (free registration required)
Related: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free)
Three psychological therapies are effective for adolescent depression
22 Jul, 2017 | 22:30h | UTCThree psychological therapies are effective for adolescent depression – NIHR Signal (free)
Original article: Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial – The Lancet Psychiatry (free) AND Commentaries: From efficacy to pragmatic trials: does the dodo bird verdict apply? – The Lancet Psychiatry? (free) AND New ways to treat depression in teenagers – The Conversation (free)
“Three psychological therapies equally effective for adolescent depression” (RT @NIHR_DC see Tweet)
Vitamin D supplements may reduce the chance of developing a chest infection
22 Jul, 2017 | 21:31h | UTCVitamin D supplements may reduce the chance of developing a chest infection – NIHR Signal (free)
Original article: Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data – The BMJ (free)
“Daily or weekly vitamin D supplements reduced chest infections, but one-off monthly dosing gave no benefit”. (RT @NIHR_DC see Tweet)
Studies Compare Types of Insulin for Reducing Episodes of Low Blood Sugar for Patients with Type 1 or 2 Diabetes
22 Jul, 2017 | 21:21h | UTCStudies Compare Types of Insulin for Reducing Episodes of Low Blood Sugar for Patients with Type 1 or 2 Diabetes – The JAMA Network (free commentary)
Original article 1: Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 1 Diabetes: The SWITCH 1 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Original article 2: Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 2 Diabetes: The SWITCH 2 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Lower rates of hypoglycemia in patients treated with insulin degludec – 2 Minute Medicine (free) AND Insulin Degludec Tied to Fewer Hypoglycemic Episodes Than Insulin Glargine – Physician’s First Watch (free)
An evidence-based, point-of-care tool to guide completion of asthma action plans in practice
22 Jul, 2017 | 21:03h | UTCRelated: Asthma self-management programmes can reduce unscheduled care – NIHR Signal (free) AND Original article: Systematic meta-review of supported self-management for asthma: a healthcare perspective – BMC Medicine (free)
Source: ACP Journal Wise ($ resource to find articles of interest)
“Researchers create practical algorithm for completing asthma action plans” (RT @PCRSUK see Tweet)
Simultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression
22 Jul, 2017 | 19:19h | UTCSimultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression, United States, 2001-2014 – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Benzodiazepines With Antidepressants May Spark Long-term Use – Medscape (free registration required) AND Antidepressants plus benzos: Is it worth the risk? – Pharmacy News (free)
In this large cohort, patients who were treated with benzodiazepine associated with antidepressants in the beginning of the treatment for depression didn’t seem to have a clinical benefit, and 12.3% of patients who began treatment with both agents had long-term (6-month) benzodiazepine use. Due to the observational nature of this study, it may be that these patients had more severe depression, but caution is advised nonetheless.
Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons
22 Jul, 2017 | 15:32h | UTCAssociation Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons – JAMA (link to abstract – $ for full-text)
Commentaries: Elevated Brain Amyloid Linked to Later Cognitive Decline – Medscape (free registration required) AND Amyloid Plaque and Cognitive Decline – Diagnostic Imaging (free) More Data Suggests Brain Amyloid Buildup Leads to Cognitive Decline – MedPage Today (free registration required) AND Elevated amyloid proves a warning sign of cognitive decline to come – Health Imaging (free) AND Study reveals early indication of Alzheimer’s in adults with normal cognition – News Medical (free)
Review: How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy
22 Jul, 2017 | 15:59h | UTCReview: How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy – Blood (free)
Prognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction
22 Jul, 2017 | 15:50h | UTCPrognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Moderate Aortic Stenosis and LV Systolic Dysfunction – American College of Cardiology, Latest in Cardiology (free) AND High Risk of Clinical Events With Moderate Aortic Stenosis Plus LVSD – Medscape (free registration required)
In this observational study, patients with concomitant moderate aortic stenosis and left ventricular dysfunction were at high risk for clinical events and death.
More Millennials Are Having Strokes
22 Jul, 2017 | 14:54h | UTCPrevalence of Cardiovascular Risk Factors and Strokes in Younger Adults – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: More Millennials Are Having Strokes – Scientific American (free) AND Ischemic stroke hospitalizations among younger adults increased 30% or more in recent years – Cardiovascular Business (free) AND Higher incidence of stroke and greater prevalence of stroke risk factors in younger adults over the last decade – 2 Minute Medicine (free) Is Stroke Trending Younger? – MedPage Today (free registration required) AND More Data Suggest Stroke Rates Rising in Younger Adults – Medscape (free registration required)
Effect of Electroacupuncture on Urinary Leakage Among Women With Stress Urinary Incontinence
22 Jul, 2017 | 14:24h | UTCEffect of Electroacupuncture on Urinary Leakage Among Women With Stress Urinary Incontinence: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Electroacupuncture linked to improvements for stress urinary incontinence – 2 Minute Medicine (free) AND Electroacupuncture May Decrease Stress Urinary Incontinence – Medscape (free registration required) AND Mixed Results on Effectiveness of Acupuncture to Treat Stress Urinary Incontinence, Infertility – The JAMA Network (free)