Family Medicine
Review: A Test in Context: Lipid Profile, Fasting Versus Nonfasting
27 Sep, 2017 | 14:06h | UTCA Test in Context: Lipid Profile, Fasting Versus Nonfasting – Journal of The American College of Cardiology (link to abstract and free infographic – $ for full-text)
Commentary: Is fasting before a lipid panel necessary? – Cardiovascular Business (free)
Related guideline: Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine (free) AND Commentary: New guidelines simplify cholesterol tests: no fasting needed – STAT (free)
Draft Recommendation Statement: Falls Prevention in Community-Dwelling Older Adults
27 Sep, 2017 | 14:07h | UTCCommentaries: USPSTF Draft Recommendations for Falls and Fracture Prevention – Medscape (free registration required) AND USPSTF Draft Statement: Vitamin D Supplements No Longer Recommended to Prevent Falls in Seniors – Physician’s First Watch (free)
Related guidelines: Falls in older people: assessing risk and prevention – NICE (free) AND Evidence-based guidelines for fall prevention in Korea (free) AND Summary of the Updated American Geriatrics Society/British Geriatrics Society Clinical Practice Guideline for Prevention of Falls in Older Persons (free PDF) AND Management of Falls in Community-Dwelling Older Adults: Clinical Guidance Statement From the Academy of Geriatric Physical Therapy of the American Physical Therapy Association (free) AND Prevention of fall-related injuries in the elderly: An Eastern Association for the Surgery of Trauma practice management guideline (free)
Meta-analysis: Efficacy of recommended drugs against soil transmitted helminths
27 Sep, 2017 | 14:04h | UTCCommentary: Reduced Efficacy of Anthelmintic Drugs – MyScience (free)
Cohort Study: Childhood onset inflammatory bowel disease and risk of cancer
27 Sep, 2017 | 14:03h | UTCEditorial: Increased risk of cancer in children with inflammatory bowel disease (free)
Commentaries: Inflammatory Bowel Disease in Childhood Tied to Higher Cancer Risk Later – Physician’s First Watch (free) AND IBD in Childhood Raises Cancer Risk – Medscape (free registration required)
Pregnant Women Should Still Get The Flu Vaccine, Doctors Advise
27 Sep, 2017 | 13:58h | UTCPregnant Women Should Still Get The Flu Vaccine, Doctors Advise – NPR (free)
Statement: It is Safe to Receive Flu Shot During Pregnancy – American College of Obstetricians and Gynecologists (free)
See original study showing a possible association between flu vaccine and miscarriage in our September 21st issue (see #6)
Clinical Report: Infectious Diseases Associated With Organized Sports and Outbreak Control
27 Sep, 2017 | 14:00h | UTCNews release: AAP Offers New Guidance on Preventing Spread of Infectious Diseases Associated with Organized Sports (free)
Commentary: When Athletes Share Infections – The New York Times (10 articles per month are free)
Randomized Controled Trial: Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control
27 Sep, 2017 | 14:02h | UTCEffect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Genotyping Reduces Adverse Events with Warfarin – Cardiobrief (free) AND Genotype-Guided Warfarin Dosing Reduces Adverse Events After Hip, Knee Arthroplasty – Physician’s First Watch (free)
Meta-analysis: Diagnostic Accuracy of Tests for Influenza
27 Sep, 2017 | 13:58h | UTCDiagnostic Accuracy of Novel and Traditional Rapid Tests for Influenza Infection Compared With Reverse Transcriptase Polymerase Chain Reaction: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Newer influenza diagnostic tests more accurate than traditional tests – Clinical Advisor (free) AND Rapid tests linked to quicker and more accurate results for influenza diagnosis than traditional tests – 2 Minute Medicine (free)
Draft Guideline: Most common ear infections should not be treated with antibiotics
25 Sep, 2017 | 22:28h | UTCNews release: Draft Guideline: Most common ear infections should not be treated with antibiotics, says NICE (free)
Commentaries: Common ear infections don’t need antibiotics, health watchdog says – The Guardian (free) AND Antibiotics not recommended for acute otitis, says NICE (free)
Cohort Study: Low-Dose Aspirin Discontinuation and Risk of Cardiovascular Events
25 Sep, 2017 | 22:27h | UTCLow-Dose Aspirin Discontinuation and Risk of Cardiovascular Events: A Swedish Nationwide, Population-Based Cohort Study – Circulation (link to abstract – $ for full-text)
Commentaries: Stopping Aspirin Hikes CV risk – Cardiobrief (free) AND Aspirin Discontinuation Tied to Increased Risk for CV Events – Physician’s First Watch (free)
Randomized Controled Trial: Continuous glucose monitoring in pregnant women with type 1 diabetes
25 Sep, 2017 | 22:23h | UTCContinuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: In Pregnant Women with Type 1 Diabetes, Continuous Glucose Monitoring Linked to Better Outcomes – Physician’s First Watch (free) AND All pregnant women with type 1 diabetes should be offered continuous glucose monitoring – OnMedica (free)
Richard Lehman’s journal review – 25 September 2017
25 Sep, 2017 | 22:22h | UTCRichard Lehman’s journal review, 25 September 2017 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Adherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction
24 Sep, 2017 | 21:37h | UTCAdherence Tradeoff to Multiple Preventive Therapies and All-Cause Mortality After Acute Myocardial Infarction – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Study Questions Incremental Benefit of Beta-Blockers After Acute MI – TCTMD (free) AND Beta blockers not needed after heart attack if other medications taken – University of North Carolina at Chapel Hill, via Eurekalert (free) AND Adherence to medications post-MI is below 50%; beta-blockers offer little incremental benefit – Cardiovascular Business (free)
Related study published recently: β-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction – Journal of The American College of Cardiology (free)
The effect of physical activity on mortality and cardiovascular disease
24 Sep, 2017 | 21:40h | UTCThe effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study – The Lancet (link to abstract – $ for full-text)
Commentaries: Any type of physical exercise is good for the heart – NHS Choices (free) AND Physical Activity of Any Ilk Cuts CVD, Deaths in Global Study: PURE – TCTMD (free) AND Being active saves lives whether a gym workout, walking to work or washing the floor – McMaster University, via ScienceDaily (free) AND Don’t overthink your exercise: just 2.5 hours per week of any kind could help you live longer – VOX (free) AND A daily half hour’s exercise could prevent 1 in 12 early deaths, study shows – Reuters (free)
Adverse drug reactions of montelukast in children and adults
24 Sep, 2017 | 21:34h | UTCAdverse drug reactions of montelukast in children and adults – Pharmacology Research & Perspectives (free)
Commentaries: Montelukast Tied to Psychiatric Adverse Events in Kids, Adults – Medscape (free registration required) AND Asthma Drug, Montelukast, Tied to Nightmares, Depression – Drugs.com (free)
Blood test and ECG may safely rule out heart attack
24 Sep, 2017 | 21:31h | UTCBlood test and ECG may safely rule out heart attack – NIHR Signal (free)
Original article: Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text) and Commentary: High-sensitivity troponin T result may help rule out of myocardial infarction – 2 Minute Medicine (free)
Meta-analysis: Antidepressants linked to increased risk of death
24 Sep, 2017 | 21:39h | UTCThe Mortality and Myocardial Effects of Antidepressants Are Moderated by Preexisting Cardiovascular Disease: A Meta-Analysis – Psychotherapy and Psychosomatics (link to abstract – $ for full-text)
Commentaries: Antidepressant use associated with higher risk of death – OnMedica (free) AND Antidepressants may raise death risk by a third – Medical News Today (free) AND Antidepressants Tied to a Significantly Increased Risk for Death – Medscape (free registration required) AND Antidepressants Associated with Significantly Elevated Risk of Death, Researchers Find – McMaster University, via NewsWise (free)
Lung Cancer Mortality Associated With Smoking and Smoking Cessation Among People Living With HIV
24 Sep, 2017 | 21:23h | UTCEditorial: If We Are Smart Enough to Stop HIV From Replicating, Why Can’t We Help People to Stop Smoking? (free)
Commentaries: People with HIV who smoke are more likely to die from lung cancer than from HIV itself – eCancer (free) AND Smoking cuts life expectancy in HIV more than AIDS does – OnMedica (free)
Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis
24 Sep, 2017 | 21:24h | UTCRandomized clinical trial of antibiotic therapy for uncomplicated appendicitis – British Journal of Surgery (link to abstract – $ for full-text)
See also a related meta-analysis suggesting the safety of nonoperative treatment for uncomplicated cases (free) and a recent guideline that incorporates the possibility of non-operative treatment for uncomplicated disease (free)
“1st RCT to show uncomplicated appendicitis resolve even without antibiotics (let alone surgery)” (RT @villesallinen see Tweet)
Weight and Metabolic Outcomes 12 Years after Gastric Bypass
24 Sep, 2017 | 21:21h | UTCWeight and Metabolic Outcomes 12 Years after Gastric Bypass – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Benefits of gastric bypass persist for 12 years – Reuters (free) AND Gastric bypass surgery benefits continue for 12 years – Diabetes.co.uk (free) AND Bariatric Surgery’s Benefits Last Over a Decade – Physician’s First Watch (free)
All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease
24 Sep, 2017 | 21:26h | UTCAll Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease – Hypertension (link to abstract – free PDF via @unpaywall)
Commentaries: Hypertensive disorders of pregnancy increase future risk of heart disease – Cardiovascular Business (free) AND A type of hypertension during pregnancy more dangerous than thought – AHA News (free)
See related articles and commentaries in our August 22nd issue (see #3)
Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
24 Sep, 2017 | 20:18h | UTCEditorial: Romosozumab — Promising or Practice Changing? (free)
Review: Advents in the Diagnosis and Management of Ischemic Colitis
24 Sep, 2017 | 20:18h | UTCAdvents in the Diagnosis and Management of Ischemic Colitis – Frontiers in Surgery (free)
Source: Critical Care Reviews Newsletter
Prevention and Control of Seasonal Influenza with Vaccines
24 Sep, 2017 | 20:10h | UTCCommentary: CDC: Updated Influenza Immunization Recommendations for 2017-2018 – MPR (free)
Review: Whooping Cough (Pertussis)
24 Sep, 2017 | 20:06h | UTCWhooping Cough (Pertussis) – U.S. Pharmacists (free)
Source: Medscape