Family Medicine
Meta-Analysis: Lactobacillus reuteri to Treat Infant Colic
13 Jan, 2018 | 18:59h | UTCLactobacillus reuteri to Treat Infant Colic: A Meta-analysis – Pediatrics (free)
Invited commentary: Is It Time To Recommend Lactobacillus for Colic? Not Necessarily (free)
Research: Age at Menarche, Depression, and Antisocial Behavior in Adulthood
13 Jan, 2018 | 18:58h | UTCAge at Menarche, Depression, and Antisocial Behavior in Adulthood – Pediatrics (free)
Commentary: Early puberty increases depression risk in adulthood – Medical News Today (free)
Position Statement on Informal Breast Milk Sharing for the Term Healthy Infant
12 Jan, 2018 | 16:40h | UTCNews release: The Academy of Breastfeeding Medicine Issues Guidance on Informal Milk Sharing for Healthy Term infants (free)
Meta-Analysis: What Proportion of People Who Try One Cigarette Become Daily Smokers?
12 Jan, 2018 | 16:39h | UTCWhat Proportion of People Who Try One Cigarette Become Daily Smokers? A Meta-Analysis of Representative Surveys – Nicotine & Tobacco Research (link to abstract – $ for full-text)
Commentaries: One cigarette ‘may lead to habit for more than two-thirds of people’ – The Guardian (free) AND Most people who try one cigarette become daily smokers, study says – BBC (free) AND At least 3 out of 5 people who try a cigarette become daily smokers – Queen Mary University of London, via ScienceDaily (free)
Research: Incremental Effects of Antihypertensive Drugs
12 Jan, 2018 | 16:27h | UTCIncremental effects of antihypertensive drugs: instrumental variable analysis – The BMJ (free)
Commentary: Addition of new class of antihypertensive drug effective for lowering BP – Clinical Advisor (free)
Guideline: Treatment of Non-neurogenic Male LUTS
10 Jan, 2018 | 23:24h | UTCTreatment of Non-neurogenic Male LUTS – European Urology Association (free, but not accessible via mobile devices) (via @KariTikkinen)
Review: Non-alcoholic Fatty Liver Disease
10 Jan, 2018 | 23:17h | UTC
Guideline: Pharmacological Treatment of Patients With Alcohol Use Disorder
10 Jan, 2018 | 23:18h | UTCNews release: APA Releases New Practice Guideline on Treatment of Alcohol Use Disorder – American Psychiatry Association (free)
Commentary: New Alcohol Use Disorder Guideline Emphasizes Medication – Medscape (free registration required)
Research: Effect of Physical Activity on Frailty
10 Jan, 2018 | 23:16h | UTCEffect of Physical Activity on Frailty: Secondary Analysis of a Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Structured exercise may offer mobility benefits to all older patients, regardless of frailty – ACP Internist (free) AND Exercise may reduce disability even in frail elders – Reuters (free) AND Effect of Physical Activity on Frailty – Summary for Patients, Annals of Internal Medicine (free)
Meta-Analysis: Patent Forame Ovale Closure Tied to Lower Risk for Recurrent Stroke
10 Jan, 2018 | 23:15h | UTCPercutaneous PFO Closure Tied to Lower Risk for Recurrent Stroke – Physician’s First Watch (free) AND Meta-Analyses Support Stroke Prevention With PFO Closure – MedPage Today (free registration required)
Original article 1: Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Original article 2: Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Research: Use of Folic Acid and Multivitamins During Pregnancy and Risk of Autism in Offspring
10 Jan, 2018 | 00:34h | UTCCommentaries: Use of Folic Acid and Multivitamins During Pregnancy May Lower Autism Risk – Psychiatry News Alert (free) AND Folic Acid, Multivitamins During Pregnancy May Cut ASD Risk – MedPage Today (free registration required) AND Are Vitamin Supplements Used Before or During Pregnancy Associated with Risk of Autism Spectrum Disorder? – The JAMA Network (free)
Research: Silent Myocardial Infarction and Long-Term Risk of Heart Failure
10 Jan, 2018 | 23:12h | UTCSilent Myocardial Infarction and Long-Term Risk of Heart Failure: The ARIC Study – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Silent MI and the Risk of Heart Failure – American College of Cardiology, Latest in Cardiology (free) AND Silent MI associated with downstream heart failure risk – Cardiovascular Business (free) AND Heart Failure Risk Following ‘Silent’ MI Warrants Scrutiny: ARIC Analysis – TCTMD (free) AND Silent MI Predicts Heart Failure, Deserves More Respect as CHD Risk Factor – Medscape (free registration required)
Prescribing Cascade in a Cardiology Practice
10 Jan, 2018 | 00:31h | UTCPrescribing Cascade in a Cardiology Practice – American College of Cardiology, Latest in Cardiology (free)
“Before starting a medication to treat a new medical condition, consider whether this condition could be a drug-related adverse event. Specifically, consider whether this could represent a prescribing cascade”.
Research: Folic Acid Supplementation During Pregnancy and Risk of Autism in Children Exposed to Antiepileptic Drugs in Utero
10 Jan, 2018 | 00:32h | UTCAssociation of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: Lack of Folic Acid Supplements During Pregnancy Linked With Increased Autism Risk in Children Exposed to Seizure Drugs In Utero – Medical Research (free) AND Folic Acid in Pregnant Women on Antiepileptic Drugs Linked to Lower Autism Risk – Medscape (free registration required) AND Folic Acid May Limit Autism Traits in Children of Epileptic Women – MedPage Today (free registration required) AND Folic acid lessens autism risk for fetal anti-epileptic exposure – MedicalXpress (free)
Richard Lehman’s journal reviews – 8 January 2018
10 Jan, 2018 | 00:23h | UTCRichard Lehman’s journal reviews, 8 January 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Review: Postpartum use of Long-Acting Contraceptives in Low- and Middle-Income Countries
10 Jan, 2018 | 00:09h | UTC
Review: Evaluation and Management of Penicillin Allergy
9 Jan, 2018 | 23:56h | UTCEvaluation and Management of Penicillin Allergy – Mayo Clinic Proceedings (free)
New eBook: Let’s Talk TB
8 Jan, 2018 | 00:51h | UTC2 – 2018 Edition: Let’s Talk TB (free PDF chapters) (via @paimadhu and @Onisillos)
“Let’s Talk TB is a book on the current best practices on TB diagnosis and treatment available for free for all GPs and private practitioners in India and other high-burden countries”
Free Online Course: Antimicrobial Stewardship
8 Jan, 2018 | 00:52h | UTCNew free online course: Antimicrobial Stewardship: A competency-based approach – World Health Organization (via @snahrgang)
See also other OpenWHO Courses
Guideline: Antibiotic Use in Adults with Acute Upper Respiratory Tract Infections
8 Jan, 2018 | 00:50h | UTC
Guidelines: Treatment of Community-Acquired Skin and Soft Tissue Infection
8 Jan, 2018 | 00:48h | UTC
Meta-Analysis: Effect of PCSK9 Inhibitors on Clinical Outcomes in Patients With Hypercholesterolemia
4 Jan, 2018 | 18:59h | UTCPCSK9 inhibitors were associated with reduced incidence of myocardial infarction (2.3% vs 3,6%), stroke (1.0% vs 1.4%) and coronary revascularization (4,2% vs 5,8%). Overall, no significant change was observed in cardiovascular or all-cause mortality.
Practice Guideline: Mild Cognitive Impairment
4 Jan, 2018 | 17:28h | UTCPractice guideline update summary: Mild cognitive impairment – American Academy of Neurology (free PDF)
Commentary: Mild cognitive impairment: a practice guideline update – Clinical Advisor (free)
“For patients diagnosed with MCI, clinicians may choose NOT to offer cholinesterase inhibitors”.
“If clinicians choose to offer cholinesterase inhibitors, they must first discuss with patients the fact that this is an off-label prescription not currently backed by empirical evidence”.
Research: Increased Cardiovascular Risk After Initiation of Inhaled Long-Acting Bronchodilators in Patients With COPD
4 Jan, 2018 | 17:16h | UTCAssociation of Cardiovascular Risk With Inhaled Long-Acting Bronchodilators in Patients With Chronic Obstructive Pulmonary Disease: A Nested Case-Control Study – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Starting new COPD inhaler tied to heart attack risk – Reuters (free) AND New Use of Long-Acting Bronchodilators in COPD Tied to Increased Cardiovascular Risk – Physician’s First Watch (free) AND COPD patients beginning inhaler therapy at greater short-term risk for CVD – Cardiovascular Business (free)
Guidelines for the Management of Acne
4 Jan, 2018 | 17:12h | UTCGuidelines for the Management of Acne: Recommendations From a French Multidisciplinary Group – British Journal of Dermatology, via Medscape (free registration required)