Family Medicine
Review: Cardiovascular Disease and COPD
11 Oct, 2018 | 20:08h | UTCCardiovascular disease and COPD: dangerous liaisons? – European Respiratory Review (free)
Study: Incidence of Progression of Persistent Non-Dysplastic Barrett’s Esophagus to Malignancy
11 Oct, 2018 | 20:01h | UTCIncidence of Progression of Persistent Non-Dysplastic Barrett’s Esophagus to Malignancy – Clinical Gastroenterology and Hepatology (link to abstract – $ for full-text)
Commentary: Patients with stable Barrett’s esophagus may need less surveillance, study finds – ACP Gastroenterology (free)
Study: Acceleration of BMI in Early Childhood and Risk of Sustained Obesity
5 Oct, 2018 | 02:45h | UTCAcceleration of BMI in Early Childhood and Risk of Sustained Obesity – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Childhood BMI Acceleration and Sustained Obesity (free)
Commentary: BMI in Early Childhood and Sustained Obesity – American College of Cardiology (free)
Perspective: Given Their Potential for Harm, It’s Time to Focus on the Safety of Supplements
5 Oct, 2018 | 02:41h | UTCGiven Their Potential for Harm, It’s Time to Focus on the Safety of Supplements – JAMA (free for a limited period) (via @NUNESDOC)
“About 23 000 visits to emergency departments each year can be attributed to adverse events from dietary supplements.”
Meta-Analysis: Effects of Vitamin D Supplementation on Musculoskeletal Health
5 Oct, 2018 | 02:44h | UTCEffects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: The Lancet Diabetes & Endocrinology: Vitamin D supplementation in adults does not prevent fractures, falls or improve bone mineral density – The Lancet (free) AND Vitamin D supplements don’t help bone health, major study concludes – The Guardian (free) AND Millions of Americans take vitamin D. Most should just stop – VOX (free)
Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline) AND Vitamin D Not Linked to Fracture Risk (free study and commentaries)
Study: Effect of Lorcaserin on Prevention and Remission of Type 2 Diabetes in Overweight and Obese Patients
5 Oct, 2018 | 02:38h | UTCEffect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Weight loss drug shows positive effect on diabetes – Brigham and Women’s Hospital (free) AND Weight Loss Drug Helped Prevent Diabetes in Overweight People – MedPage Today (free registration required)
Related Article: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients (link to abstract and commentaries)
Meta-Analysis: Prescribed Exercise with Compression vs Compression Alone in Treating Patients With Venous Leg Ulcers
5 Oct, 2018 | 02:36h | UTCPrescribed Exercise With Compression vs Compression Alone in Treating Patients With Venous Leg Ulcers: A Systematic Review and Meta-analysis – JAMA Dermatology (link to abstract – $ for full-text)
Commentaries: Adding Exercise to Compression Improves Outcomes in Venous Leg Ulcers – Physcian’s First Watch (free) AND Compressions May Remedy Venous Leg Ulcers – MedPage Today (free)
NICE Guideline: Renal Replacement Therapy
5 Oct, 2018 | 02:31h | UTC
Randomized Trial: Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears
5 Oct, 2018 | 02:21h | UTCEffect of Early Surgery vs Physical Therapy on Knee Function Among Patients With Nonobstructive Meniscal Tears: The ESCAPE Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: PT an Alternative to Surgery for Some Meniscal Tears – Physician’s First Watch (free)
Related: Adverse Outcomes After Arthroscopic Partial Meniscectomy (free study, commentary and guideline on the subject)
“Our Dutch multi center RCT demonstrates noninferiority of physical therapy compared with early surgery with arthroscopic partial meniscectomy for improving self-reported knee function in patients with nonobstructive meniscal tears.” (via @RudolfPoolman see Tweet)
Ten Principles for More Conservative, Care-Full Diagnosis
5 Oct, 2018 | 02:22h | UTCTen Principles for More Conservative, Care-Full Diagnosis – Annals of Internal Medicine (free) (via @EricTopol)
Sytematic Review: Antidepressant Withdrawal Effects
5 Oct, 2018 | 02:06h | UTCA systematic review into the incidence, severity and duration of antidepressant withdrawal effects: Are guidelines evidence-based? – Addictive Behaviours (free PDF)
Commentaries: Antidepressant withdrawal ‘hits millions’ – BBC (free) AND Antidepressant withdrawal symptoms severe, says new report – The Guardian (free)
Related: Antidepressant Withdrawal Syndrome (free review and NYT article)
Meta-Analysis: Treating Subclinical Hypothyroidism is Not Associated with Quality of Life and Thyroid-Related Symptoms
5 Oct, 2018 | 02:18h | UTCAssociation of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Most Patients With Subclinical Hypothyroidism May Not Require Thyroid Medication – MedicalResearch.com (free) AND Hormone Tx May Not Benefit Subclinical Hypothyroidism – MedPage Today (free registration required) AND Treating Subclinical Hypothyroidism Is of Little Benefit – Medscape (free registration required)
Randomized Trial: Low-Dose Amitriptyline for Chronic Low Back Pain
5 Oct, 2018 | 02:00h | UTCEfficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Low-dose antidepressants ease back pain – Australian Hospital + Healthcare Bulletin (free) AND Antidepressant Amitriptyline Might Help Ease Low Back Pain – Physician’s First Watch (free)
Clinical Guide: Neuro-Ophthalmology at the Bedside
5 Oct, 2018 | 02:02h | UTCNeuro-Ophthalmology at the bedside: A clinical guide – Journal of Neurosciences in Rural Practice (free)
Randomized Trial: Drinking More Water Prevents Recurrent Cystitis
5 Oct, 2018 | 01:48h | UTCEditorial: Drinking More Water for Prevention of Recurrent Cystitis (free)
Commentaries: Drinking more water reduces bladder infections in women – UT Southwestern Medical Center (free) AND Drinking more water linked to fewer bladder infections in women – UPI (free)
Report: Taking Action on Childhood Obesity Report
5 Oct, 2018 | 01:47h | UTCTaking action on childhood obesity report – World Health Organization (free PDF) (via @equitylist)
Supplement: Practical Guide for Allergy and Immunology in Canada 2018
5 Oct, 2018 | 01:46h | UTCPractical guide for allergy and immunology in Canada 2018 – Allergy, Asthma & Clinical Immunology (free reviews)
An introduction to immunology and immunopathology
Allergen-specific immunotherapy
Non-IgE-mediated food hypersensitivity
Early introduction of foods to prevent food allergy
Zackary Berger’s Journal Reviews, 1 October 2018
5 Oct, 2018 | 01:43h | UTCZackary Berger’s journal reviews, 1 October 2018 – The BMJ Opinion (free)
WHO Launches SAFER Alcohol Control Initiative
5 Oct, 2018 | 01:36h | UTCSee also: SAFER High Impact Strategies (free)
Related: WHO Global Status Report on Alcohol and Health 2018 (free report and commentaries)
Study: Language Experience in the Second Year of Life and Language Outcomes in Late Childhood
5 Oct, 2018 | 01:37h | UTCLanguage Experience in the Second Year of Life and Language Outcomes in Late Childhood – Pediatrics (free)
Commentaries: Early Language Exposure and Middle School Language and IQ: Implications for Primary Prevention – Pediatrics (free) AND Conversations Between Parents and Toddlers Help Build Intelligence and Vocabulary – Journal Watch (free)
Study: CT Screening for Early Lung Cancer Reduces Lung Cancer Mortality
5 Oct, 2018 | 01:31h | UTCWCLC 2018: NELSON Study: CT Screening for Early Lung Cancer Reduces Lung Cancer Mortality – The ASCO Post (free)
Related: NELSON lung cancer study encourages widespread screening, Medicare reimbursement – Health Imaging (free) AND Second Large Study Shows That Lung Cancer Screening Works – Medscape (free registration required)
Video: KHN Conversation on Overtreatment
5 Oct, 2018 | 01:33h | UTCKHN Conversation on Overtreatment – Kaiser Health News (free)
Commentary: Changing Healthcare’s Culture of Overtreatment a Challenge – MedPage Today (free registration required)
Related KHN Series: Treatment Overkill (free articles)
Podcast: Geriatric Psychiatry
5 Oct, 2018 | 01:29h | UTCRelated Podcast: #115 Geriatric Depression – The Curbsiders Internal Medicine Podcast (free)
Meta-Analysis: Effects of Coenzyme Q10 on Statin‐Induced Myopathy
5 Oct, 2018 | 01:27h | UTCCommentary: Coenzyme Q10 reduces statin-induced myopathy symptoms – Univadis (free registration required)
Guideline Summary: 2018 IDSA Guidelines for Clostridium Difficile Infection
5 Oct, 2018 | 01:24h | UTCRelated Guidelines: Clinical Practice Guidelines for Clostridium difficileInfection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) – Clinical Infectious Diseases (free) AND The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines – GUT (free)