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Family Medicine

Study: Short Interpregnancy Intervals are Associated with Increased Risks for Adverse Pregnancy Outcomes

2 Nov, 2018 | 03:31h | UTC

Association of Short Interpregnancy Interval With Pregnancy Outcomes According to Maternal Age – JAMA Internal Medicine (free for a limited period)

Commentaries: Balancing the Risks and Desires for Pregnancy in Older Mothers: Increasing Morbidity, Declining Fertility – JAMA Internal Medicine (free for a limited period) AND Women ‘should leave at least a year between pregnancies’ – NHS Choices (free) AND Waiting a year between pregnancies lowers health risks, study says – CNN (free) AND Study: Do Even Older Moms Have To Wait 18 Months Between Pregnancies? – CommonHealth (free)

 


Meta-Analysis: Cannabinoids for the Treatment of Chronic Noncancer Pain Conditions

2 Nov, 2018 | 03:29h | UTC

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies – Pain (free)

“It seems unlikely that cannabinoids are highly effective medicines for chronic noncancer pain conditions.”

 


Systematic Review: Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation

2 Nov, 2018 | 03:18h | UTC

Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic Review – Annals of Internal Medicine (free)

Commentary: DOACs in AF: Observational and Randomized Studies Don’t Always Agree – Medscape (free registration required)

 


Alex Nowbar’s research reviews – 29 October 2018

2 Nov, 2018 | 02:52h | UTC

Alex Nowbar’s research reviews, 29 October 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Cohort Study: Comparative Effectiveness and Safety of Bariatric Procedures for Weight Loss

2 Nov, 2018 | 02:56h | UTC

Comparative Effectiveness and Safety of Bariatric Procedures for Weight Loss: A PCORnet Cohort Study – Annals of Internal Medicine (free)

Commentaries: Effectiveness and Safety of Bariatric Procedures for Weight Loss – Annals of Internal Medicine (free) AND Gastric bypass surgery associated with greater weight loss in adults – Kaiser Permanente (free)

 


Systematic Review: Drug-Induced Interstitial Lung Disease

2 Nov, 2018 | 02:54h | UTC

Drug-Induced Interstitial Lung Disease: A Systematic Review – Journal of Clinical Medicine (free)

Commentary: Drugs’ side effects in lungs ‘more widespread than thought’ – The University of Manchester (free)

 


Cohort Study: Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension

2 Nov, 2018 | 02:44h | UTC

Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension – JAMA Internal Medicine (free for a limited period)

Commentaries: Treatment for moderately high blood pressure may be best saved for those at high risk – University of Cambridge (free) AND Study Questions Whether Treating Mild Hypertension Benefits Patients – NEJM Journal Watch (free)

 


Podcast: Headaches Advanced Class

2 Nov, 2018 | 02:49h | UTC

#122 Headaches Advanced Class: Migraines, medication overuse, and more! – Curbsiders Internal Medicine Podcast (free audio and summary)

 


Cohort Study: A Healthy Lifestyle Cuts Stroke Risk, Irrespective of Genetic Risk

2 Nov, 2018 | 02:41h | UTC

Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants – The BMJ (free)

Commentary: A healthy lifestyle cuts stroke risk, irrespective of genetic risk – University of Cambridge (free)

 


Perspective: Overdiagnosis of Penicillin Allergy Leads to Costly, Inappropriate Treatment

2 Nov, 2018 | 02:23h | UTC

Overdiagnosis of Penicillin Allergy Leads to Costly, Inappropriate Treatment – JAMA (free for a limited period)

Related: NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk (free) AND Antibiotic Use After Removal of Penicillin Allergy Label (link to abstract and commentaries) AND Allergy Testing in Children With Low-Risk Penicillin Allergy Symptoms (link to abstract and commentaries)

 


Position Paper: Palliative Care in Chronic Lung Diseases

2 Nov, 2018 | 02:22h | UTC

Danish respiratory society position paper: palliative care in patients with chronic progressive non-malignant lung diseases – European Clinical Respiratory Journal (free)

 


Guideline: Antiplatelet Therapy in Patients Undergoing Elective Invasive Procedures

26 Oct, 2018 | 02:58h | UTC

Management of antiplatelet therapy in patients undergoing elective invasive procedures. Proposals from the French Working Group on perioperative haemostasis (GIHP) and the French Study Group on thrombosis and haemostasis (GFHT). In collaboration with the French Society for Anaesthesia and Intensive Care Medicine (SFAR) (free)

 


Randomized Trial: Low-Dose Imipramine for Refractory Functional Dyspepsia

26 Oct, 2018 | 02:47h | UTC

Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Refractory functional dyspepsia: low-dose imipramine safe, effective – Univadis (free registration required)

 


Cohort Study: Angiotensin Converting Enzyme Inhibitors and Risk of Lung Cancer

26 Oct, 2018 | 02:43h | UTC

Angiotensin converting enzyme inhibitors and risk of lung cancer: population based cohort study – The BMJ (free)

Editorial: Angiotensin converting enzyme inhibitors and lung cancer (free)

Commentaries: Blood pressure drug linked to possible small increased risk of lung cancer – NHS Choices (free) AND Expert reaction to study looking at blood pressure drugs and lung cancer risk – Science Media Centre (free)

 


Meta-Analysis: Efficacy, Effectiveness, and Safety of Herpes Zoster Vaccines

26 Oct, 2018 | 02:42h | UTC

Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis – The BMJ (free)

“Using the adjuvant recombinant subunit vaccine might prevent more cases of herpes zoster than using the live attenuated vaccine, but the adjuvant recombinant subunit vaccine also carries a greater risk of adverse events at injection sites.”

 


Observational Study: Blood Pressure Levels and Outcomes in Patients With Diabetes Mellitus and Coronary Artery Disease

26 Oct, 2018 | 02:36h | UTC

Average Clinician‐Measured Blood Pressures and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease in the EXAMINE Trial – Journal of the American Heart Association (free)

Editorial: The Ongoing Saga of Optimal Blood Pressure Level in Patients With Diabetes Mellitus and Coronary Artery Disease (free)

“A U‐shaped relationship between cardiovascular outcomes and BPs was observed.”

 


Observational Study: Blood Pressure Levels and Outcomes in Patients With Peripheral Artery Disease

26 Oct, 2018 | 02:33h | UTC

Association of Blood Pressure Measurements With Peripheral Artery Disease Events: Reanalysis of the ALLHAT Data – Circulation (free)

Editorial: New Curveball for Hypertension Guidelines? Blood Pressure Targets in Peripheral Artery Disease (free)

“we found a higher rate of lower extremity PAD events with higher and lower SBP and pulse pressure and with lower DBP.”

 


Meta-Analysis: Self-Monitoring of Blood Glucose Provides no Important Benefit for Most People with Type 2 Diabetes

26 Oct, 2018 | 02:30h | UTC

Self-monitoring of blood glucose provides no important benefit for most people with type 2 diabetes – NIHR Signal (free)

Original Article: Self-monitoring blood glucose improves glycemic control in type 2 diabetes without intensive treatment: A systematic review and meta-analysis – Diabetes Research and Clinical Practice (link to abstract – $ for full-text)

 


USPSTF Statement: Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults

26 Oct, 2018 | 02:28h | UTC

Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: US Preventive Services Task Force Final Recommendation Statement – JAMA (free)

Editorials: Challenges and Opportunities for Studying Routine Screening for Abuse (free) AND Addressing Intimate Partner Violence and Abuse of Older or Vulnerable Adults in the Health Care Setting—Beyond Screening (free)

 


Perspective: The Problem with Probiotics

26 Oct, 2018 | 02:08h | UTC

The Problem With Probiotics – The New York Times (free)

Related: Probiotic Safety—No Guarantees (free perspective)

“There are potential harms as well as benefits, and a lot of wishful thinking and imprecision in the marketing of products containing them.”

 


Order Wisely Video Lectures: Appropriate Use of Tests & Treatments

26 Oct, 2018 | 01:55h | UTC

Order Wisely®: Appropriate use of tests & treatments – High Value Practice Academic Alliance (free) (via @KariTikkinen)

Comprehensive educational program that reviews appropriate use of imaging exams, lab tests, medications, transfusions and procedures to promote high-value practice.

 


Podcast: HIV Care for the Internist

26 Oct, 2018 | 01:48h | UTC

#121 HIV Care for the Internist – Curbsiders Internal Medicine Podcast (free audio and summary)

 


Alex Nowbar’s Research Reviews, 22 October 2018

26 Oct, 2018 | 01:47h | UTC

Alex Nowbar’s research reviews—22 October 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Want to Keep Your Brain Sharp? Take Care of Your Eyes And Ears

26 Oct, 2018 | 01:46h | UTC

Want To Keep Your Brain Sharp? Take Care Of Your Eyes And Ears – NPR (free)

Related Articles: Longitudinal Relationship Between Hearing Aid Use and Cognitive Function in Older Americans – Journal of the American Geriatrics Society (free) AND Cataract surgery and age-related cognitive decline: A 13-year follow-up of the English Longitudinal Study of Ageing – NPR (free)

 


Randomized Trial: Theophylline Not Effective at Reducing COPD Exacerbations

26 Oct, 2018 | 01:44h | UTC

Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPD: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: TWICS results suggest no role for low-dose theophylline as add-on therapy in COPD – Medwire News (free) AND Low-Dose Theophylline Not Effective at Reducing COPD Exacerbations, Study Finds – AJMC (free)

 


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