Family Medicine
The Alzheimer’s Disease Clinical Spectrum: Diagnosis and Management
1 Feb, 2019 | 02:38h | UTC
Randomized Trial: E-Cigarettes vs. Nicotine-Replacement Therapy
30 Jan, 2019 | 23:35h | UTCA Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy – New England Journal of Medicine (link to abstract – $ for full-text)
Editorial: The Dangerous Flavors of E-Cigarettes (free)
Commentaries: E-cigarettes more effective than nicotine replacement therapies, finds major trial – Queen Mary University of London (free) AND UK study shows e-cigarettes help adult smokers quit, but US experts urge caution – CNN (free) AND E-Cigarettes Are Effective at Helping Smokers Quit, a Study Says – The New York times (10 articles per month are free) AND E-cigarettes ‘much better for quitting smoking’ – BBC (free) AND Study Found Vaping Beat Traditional Smoking-Cessation Options – NPR (free)
Related Commentary on Twitter
Trial finds e-cigarettes more effective than nicotine-replacement therapy with respect to the 1-year abstinence rate (18% vs. 10%). Throat or mouth irritation was more common with e-cigarettes, and nausea was more common with nicotine-replacement. https://t.co/cyEnDP630v pic.twitter.com/1je5vN87ru
— NEJM (@NEJM) January 30, 2019
Perspective: Are Probiotics Money Down the Toilet? Or Worse?
30 Jan, 2019 | 23:34h | UTCAre Probiotics Money Down the Toilet? Or Worse? – JAMA (free for a limited period)
Related: Randomized Trials: Probiotics Ineffective Against Gastroenteritis (link to abstract and commentaries) AND Perspective: The Problem with Probiotics (free commentaries) AND Probiotics: Does the Evidence Match the Hype? (link to abstract and commentaries) AND Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries)
ESC Position Statement: Depression and Coronary Heart Disease
30 Jan, 2019 | 23:30h | UTC
Observational Study: β-Blocker Therapy Reduces the Risk for COPD Hospitalization
30 Jan, 2019 | 01:22h | UTCCommentary: Beta-Blocker Use Linked to Lower Risk for COPD Hospitalization – NEJM Journal Watch (free)
Related review and meta-analysis: Beta-blockers in patients with chronic obstructive disease and coexistent cardiac illnesses – COPD Research and Practice (free) AND Beta-blocker use and COPD mortality: a systematic review and meta-analysis – BMC Pulmonary Medicine (free)
Related observational studies: β-Blockers in COPD: A Cohort Study From the TONADO Research Program – CHEST (free) AND Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study – The BMJ (free)
Study: Patients with Type 2 Diabetes Safely Switched from Analog to Less Costly Human Insulin
30 Jan, 2019 | 01:13h | UTCImplementation of a Health Plan Program for Switching From Analogue to Human Insulin and Glycemic Control Among Medicare Beneficiaries With Type 2 Diabetes – JAMA (link to abstract – $ for full-text)
Commentary: Medicare Patients with Type 2 Diabetes Safely Switched From Analog to Human Insulin, JAMA Study Finds – AJMC (free)
Related: Meta-Analysis: Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes (link to abstract and commentaries) AND Retrospective Observational Study: Basal Insulin Analogs vs NPH Insulin for Type 2 Diabetes (link to abstract and commentaries)
“Patients with type 2 diabetes (T2D) enrolled in a CareMore Health Medicare Part D plan switched from analog to human insulin without significant loss of glycemic control while saving millions for themselves and for the health plan.: (from AJMC)
Ann Robinson’s Research Reviews, 29 January 2019
30 Jan, 2019 | 01:05h | UTCAnn Robinson’s research reviews, 29 January 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
Systematic Review: Point-of-Care Ultrasound in General Practice
30 Jan, 2019 | 00:58h | UTCPoint-of-Care Ultrasound in General Practice: A Systematic Review – Annals of Family Medicine (free)
FSRH Clinical Guidance: Combined Hormonal Contraception
30 Jan, 2019 | 00:47h | UTCCommentaries: No benefit to contraception pill intervals — according to guidance – OnMedica (free) AND Is it OK to take the pill every day without a break? – BBC News (free)
British Guideline for the Management of Neisseria Gonorrhoeae
30 Jan, 2019 | 00:51h | UTCCommentary: UK Gonorrhea Guideline Guards Against Antibiotic Resistance – MD Magazine (free)
Related Guideline: WHO Guidelines for the Treatment of Neisseria gonorrhoeae – World Health Organization (free)
Study: Screen Time and Children’s Performance on Developmental Test
29 Jan, 2019 | 18:16h | UTCAssociation Between Screen Time and Children’s Performance on a Developmental Screening Test – JAMA Pediatrics (free for a limited period)
Commentaries: Expert reaction to study on use of screen time and child development – Science Media Centre (free) AND Too much toddler screen time tied to worse social, motor skills by kindergarten – Reuters (free) AND More screen time for toddlers is tied to poorer development a few years later, study says – CNN (free) AND Screen time ‘may harm toddlers’ – BBC (free) AND Screen time predicts delays in child development, says new research – The Conversation (free)
Related Guidelines: Media devices in pre-school children: the recommendations of the Italian pediatric society – Italian Journal of Pediatrics (free) AND Media and Young Minds – Recommendations from The American Academy of Pediatrics (free)
See also: Children, Adolescents and Screens: What We Know and What We Need To Learn (Pediatrics Supplement with free articles)
Atrial Fibrillation Guideline: 2019 AHA/ACC/HRS Focused Update
29 Jan, 2019 | 00:08h | UTCNews Release: Updated treatment guidelines for atrial fibrillation recommend a new class of blood thinners to help prevent stroke – American Heart Association (free)
Commentaries: Focused Update of the AHA/ACC/HRS Atrial Fibrillation Guideline – American College of Cardiology (free) AND
Randomized Trial: Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia
29 Jan, 2019 | 00:05h | UTCEffect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Prevention of Cognitive Impairment With Intensive Systolic Blood Pressure Control (free for a limited period)
Commentaries: Does intensive blood pressure control reduce dementia? – NIH News Releases (free) AND Intensive BP Control Helps Prevent Mild Cognitive Impairment – NEJM Journal Watch (free)
Related Commentary on Twitter
Among ambulatory adults with hypertension, treatment to
an SBP goal < 120 mm Hg did not reduce risk of #dementia compared with a goal < 140, but did reduce risk of mild cognitive impairment and risk of a composite of MCI or probable dementia. https://t.co/hJFckI5iAx #MCI pic.twitter.com/K0tdHspupy— JAMA (@JAMA_current) January 28, 2019
Study: Human Papillomavirus Vaccine Effectiveness and Herd Protection in Young Women
29 Jan, 2019 | 00:00h | UTCHuman Papillomavirus Vaccine Effectiveness and Herd Protection in Young Women – Pediatrics (free)
Commentaries: Three Important Findings From a Study on HPV “Real World” Effectiveness – Pediatrics (free) AND HPV vaccine effective against infection and for herd immunity – 2 Minute Medicine (free)
Related Perspective on Herd Immunity: The Herd to the Rescue: How an Invisible Shield Can Keep us Healthy (free)
European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care
29 Jan, 2019 | 00:07h | UTC
Meta-Analysis: Aerobic Exercise for Adult Patients with Major Depressive Disorder
28 Jan, 2019 | 23:49h | UTCCommentary: Aerobic exercise is an effective treatment for depression – NIHR Signal (free)
Related Study: Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study – JAMA Psychiatry (link to abstract – $ for full-text) AND Commentary: Exercise can reduce risk for depression, research shows – UPI (free)
Diabetes Guidelines: Key Messages for Family Physicians
27 Jan, 2019 | 20:41h | UTCOriginal Guideline: Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free) AND Quick Reference Guide (free PDF)
See also: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND Standards of Medical Care in Diabetes—2019 Abridged for Primary Care Providers (free PDF)
Report: The Efficacy and Safety of Vertebral Augmentation
27 Jan, 2019 | 20:19h | UTCCommentaries: Spinal Fractures Can Be Terribly Painful. A Common Treatment Isn’t Helping – The New York Times (10 articles per month are free) AND Spinal Fusions Ineffective for Fracture Pain, Says ASBMR – Medscape (free registration required)
Related: Randomized Trial: Vertebroplasty vs. Sham Procedure for Acute Osteoporotic Vertebral Compression Fractures – The BMJ (free study and commentary) AND Cochrane Review: percutaneous vertebroplasty for osteoporotic vertebral compression fracture (free article and summary)
Hypothyroidism in the Elderly: Who Should Be Treated and How?
27 Jan, 2019 | 20:09h | UTCHypothyroidism in the Elderly: Who Should Be Treated and How? – Journal of the Endocrine Society (free)
Related: Meta-Analysis: Treating Subclinical Hypothyroidism is Not Associated with Quality of Life and Thyroid-Related Symptoms (link to abstract and commentaries) AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)
Beyond Chronic Kidney Disease: The Diagnosis of Renal Disease in the Elderly as an Unmet Need
27 Jan, 2019 | 18:43h | UTC
Cohort Study: Association of Fried Food Consumption with All Cause, Cardiovascular, and Cancer Mortality
24 Jan, 2019 | 21:40h | UTCCommentaries: Eating Fried Foods Linked To Heart Disease, Earlier Deaths In Women Over 50 – Kaiser Health News (free) AND Fried Foods Tied to Heart Disease in Women – The New York Times (10 articles per month are free)
Position Statement: Exercise Training for Patients with Type 2 Diabetes and Cardiovascular Disease
24 Jan, 2019 | 21:39h | UTCCommentaries: Physical activity reduces mortality in patients with diabetes: Exercise programs for diabetics are a cost effective treatment and should be reimbursed – European Society of Cardiology (free) AND Exercise Must Be a Prescription for Those With Type 2 Diabetes, European Cardiologists Say – AJMC (free) AND Exercise cuts mortality risk for people with type 2 diabetes, report says – UPI (free)
Observational Study Suggests Potential Mental Health Benefits with the Use of Common Drugs
24 Jan, 2019 | 16:28h | UTCCommentaries: Can Some Common Drugs Also Benefit Mental Health? – PsychCentral (free) AND 3 common drugs associated with reduced risk of hospitalization and harm in serious mental illness – ACP Internist (free)
Systematic Review: Interventions for Emergency Contraception
24 Jan, 2019 | 00:19h | UTCInterventions for emergency contraception – Cochrane Library (free)
Summary: Methods of emergency contraception – Cochrane Library (free)
Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease
24 Jan, 2019 | 00:21h | UTCRandomized Delayed-Start Trial of Levodopa in Parkinson’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Good News, Bad News on Levodopa for Parkinson’s Disease – U.S. News (free)