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[Preprint] Factors Associated with Worse Outcomes Among 4,103 Patients with COVID-19 in New York City

13 Apr, 2020 | 00:09h | UTC

Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City – medRxiv

 


COVID-19 Testing: The Threat of False-Negative Results

13 Apr, 2020 | 00:04h | UTC

COVID-19 Testing: The Threat of False-Negative Results – Mayo Clinic Proceedings

Commentary: False-negative COVID-19 test results may lead to false sense of security – Mayo Clinic

 


New Clinical Score: Prediction for Progression Risk in Patients with COVID-19 Pneumonia

12 Apr, 2020 | 23:58h | UTC

Prediction for Progression Risk in Patients with COVID-19 Pneumonia: the CALL Score – Clinical Infectious Diseases

Prediction for Progression Risk in Patients with COVID-19 Pneumonia: the CALL Score – Comorbidity; older Age; Lower lymphocyte; and higher Lactate dehydrogenase at presentation were independent high-risk factors for COVID-19 progression. (via @veselov78 see Tweet)

Related: Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal – The BMJ

 


NICE Publishes new COVID-19 Guidelines on Cystic Fibrosis, COPD and Dermatological Conditions

10 Apr, 2020 | 03:22h | UTC

News Release: NICE publishes new COVID-19 guidelines on cystic fibrosis, chronic obstructive pulmonary disease (COPD) and dermatological conditions – National Institute for Health and Care Excellence

See New COVID-19 Rapid Guidelines: Community-based care of patients with chronic obstructive pulmonary disease (COPD) AND Cystic fibrosis AND Dermatological conditions treated with drugs affecting the immune response

See Other COVID-19 Rapid Guidelines: Severe asthma AND Managing suspected or confirmed pneumonia in adults in the community AND Rheumatological autoimmune, inflammatory and metabolic bone disorders AND Managing symptoms (including at the end of life) in the community AND Critical care in adults AND Hematopoietic stem cell transplantation AND Dialysis service delivery AND Delivery of radiotherapy AND Delivery of systemic anticancer treatments

 


New CDC Guidance for Critical Infrastructure Workers Who May Have Had Exposure to COVID-19

10 Apr, 2020 | 03:15h | UTC

Implementing Safety Practices for Critical Infrastructure Workers Who May Have Had Exposure to a Person with Suspected or Confirmed COVID-19 – Centers for Disease Control and Prevention

Commentary: White House Announces New Guidance For How Critical Employees Can Return To Work – NPR

 


Children’s Story Books Released to Help Children Cope with COVID-19

10 Apr, 2020 | 03:09h | UTC

1 – News Release: Children’s story book released to help children and young people cope with COVID-19 – World Health Organization AND Book 1: My Hero is You, How kids can fight COVID-19

2 – News Releases: Hans and the Gruffalo? LSHTM supporting children’s COVID-19 education – London School of Hygiene & Tropical Medicine AND Released today: a free information book explaining the coronavirus to children, illustrated by Gruffalo illustrator Axel Scheffler – Nosy Crow AND Book 2: Coronavirus: A Book for Children

 


Consensus Recommendations: Caring for Patients with Pain During the COVID-19 Pandemic

10 Apr, 2020 | 03:13h | UTC

Caring for patients with pain during the COVID-19 pandemic: Consensus recommendations from an international expert panel – Anaesthesia

 


Meta-Analysis: Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples

10 Apr, 2020 | 03:03h | UTC

Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from the Hong Kong Cohort and Systematic Review and Meta-analysis – Gastroenterology

Commentary: Gastrointestinal Aspects of COVID-19 – NEJM Journal Watch

 


Analysis: Face Masks for the Public During the Covid-19 Crisis

10 Apr, 2020 | 02:58h | UTC

Face masks for the public during the covid-19 crisis – The BMJ

Commentary: Time to encourage people to wear face masks as a precaution, say experts – The BMJ

Related: Covid-19: What is the evidence for cloth masks? – The BMJ AND Covid-19: Should cloth masks be used by healthcare workers as a last resort? – The BMJ

“- The precautionary principle states we should sometimes act without definitive evidence, just in case

– Whether masks will reduce transmission of covid-19 in the general public is contested

– Even limited protection could prevent some transmission of covid-19 and save lives

– Because covid-19 is such a serious threat, wearing masks in public should be advised”

See also: CDC Now Recommends Wearing Cloth Face Coverings in Public Settings (statement and commentaries)

 


Managing the Supportive Care Needs of Those Affected by COVID-19

10 Apr, 2020 | 03:01h | UTC

Managing the supportive care needs of those affected by COVID-19 – European Respiratory Journal

 


Olfactory Loss Function as a Possible Symptom of COVID-19

10 Apr, 2020 | 02:55h | UTC

Sudden and Complete Olfactory Loss Function as a Possible Symptom of COVID-19 – JAMA Otolaryngology-Head & Neck Surgery

Related Position Statement: Loss of sense of smell as marker of COVID-19 infection – ENTUK

Related Articles: Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study – Clinical Infectious Diseases AND [Preprint] Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak – medRxiv

 


Podcast: Reusing Face Masks and N95 Respirators

10 Apr, 2020 | 02:54h | UTC

Coronavirus (COVID-19) Update: Reusing Face Masks and N95 Respirators – JAMA

Related Report: N95 mask can be decontaminated without decreasing filtration efficiency – Stanford Medicine

Related Website: N95DECON: A scientific consortium for data-driven study of N95 filtering facepiece respirator decontamination AND Commentary: New website explains how hospitals can decontaminate and reuse scarce N95 masks to fight COVID-19 – Stanford News

Related Guidance: N95 Re-Use Instructions – SAGES

 


COVID‐19 And Older Adults: What We Know

10 Apr, 2020 | 02:47h | UTC

Review: COVID‐19 And Older Adults: What We Know – Journal of the American Geriatrics Society

 


Review: Should Chloroquine and Hydroxychloroquine be Used to Treat COVID-19?

10 Apr, 2020 | 02:50h | UTC

Should chloroquine and hydroxychloroquine be used to treat COVID-19? A rapid review – BJGP Open

“At present, there is insufficient evidence to determine whether CQ/HCQ are safe and effective treatments for COVID-19”

 


Study: The COVID-19 Coronavirus Disease May Be Twice As Contagious As We Thought

9 Apr, 2020 | 03:48h | UTC

The COVID-19 Coronavirus Disease May Be Twice As Contagious As We Thought – Forbes

Original Study: High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2 – CDC Emerging Infectious Diseases

 


Systematic Review: How Effective is Quarantine to Control Coronavirus (COVID-19)?

9 Apr, 2020 | 03:50h | UTC

Quarantine alone or in combination with other public health measures to control COVID‐19: a rapid review – Cochrane Library

Commentary: How effective is quarantine alone or in combination with other public health measures to control coronavirus (COVID-19)? – Cochrane Library

 


Video: Coronavirus Q&A with Anthony Fauci, MD

9 Apr, 2020 | 03:54h | UTC

Coronavirus Q&A with Anthony Fauci, MD – JAMA

 


Podcast: Emerging Tools in the Fight Against Covid-19

9 Apr, 2020 | 03:53h | UTC

Interview with Dr. Eric Rubin and Dr. Lindsey Baden on emerging tools in the fight against Covid-19. – New England Journal of Medicine

 


Editorial: Chloroquine and Hydroxychloroquine in Covid-19

9 Apr, 2020 | 03:47h | UTC

Chloroquine and hydroxychloroquine in covid-19 – Tue BMJ

“Use of these drugs is premature and potentially harmful.”

 


Study: Population-level COVID-19 Mortality Risk

9 Apr, 2020 | 03:38h | UTC

[Preprint] Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters – medRxiv

“CONCLUSIONS: People <65 years old have very small risks of COVID-19 death even in the hotbeds of the pandemic and deaths for people <65 years without underlying predisposing conditions are remarkably uncommon. Strategies focusing specifically on protecting high-risk elderly individuals should be considered in managing the pandemic.”

Related perspectives from the same author:

Video: Perspectives on the Pandemic with Dr. John Ioannidis

Podcast: Be it resolved, we are making high-stakes decisions about the COVID-19 pandemic without reliable data. – Munk Debates Podcast

Editorial: Coronavirus disease 2019: the harms of exaggerated information and non‐evidence‐based measures – European Journal of Clinical Investigation

Opinion Piece: A fiasco in the making? As the coronavirus pandemic takes hold, we are making decisions without reliable data – STAT

 


AHA Guidance: Caution Recommended on COVID-19 Treatment with Hydroxychloroquine and Azithromycin for Patients with Cardiovascular Disease

9 Apr, 2020 | 03:45h | UTC

Considerations for Drug Interactions on QTc in Exploratory COVID-19 (Coronavirus Disease 2019) Treatment – Circulation

News Release: Caution recommended on COVID-19 treatment with hydroxychloroquine and azithromycin for patients with cardiovascular disease – American Heart Association

Commentaries: Medical groups urge caution when using hydroxychloroquine, azithromycin to treat COVID-19 patients with CVD – Cardiovascular Business AND AHA, ACC, HRS Caution Use of COVID-19 Therapies Hydroxychloroquine and Azithromycin in Cardiac Patients – DAIC

 


Safety Considerations with Chloroquine, Hydroxychloroquine and Azithromycin in the Management of SARS-CoV-2 Infection

9 Apr, 2020 | 03:42h | UTC

Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection – Canadian Medical Association Journal

Commentary: Potential harms of chloroquine, hydroxychloroquine and azithromycin for treating COVID-19 – Canadian Medical Association Journal

 


Antibody Responses to SARS-CoV-2 in a COVID-19 Recovered Patient Cohort

9 Apr, 2020 | 03:34h | UTC

[Preprint] Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications – medRxiv

Commentaries: expert reaction to preprint (not a published paper) on antibody responses to the COVID-19 virus (SARS-CoV-2) in a group of recovered people in Shanghai – Science Media Centre AND Covid-19 Antibody Update for April 8 – Science Translational Medicine AND Coronavirus: low antibody levels raise questions about reinfection risk – South China Morning Post

 


Editorials: Covid-19 Testing Times

9 Apr, 2020 | 03:26h | UTC

Covid-19: testing times – The BMJ

See also: Humanity tested – Nature Biomedical Engineering

 


PCR Assays May Turn Positive After Discharge

9 Apr, 2020 | 03:29h | UTC

PCR Assays Turned Positive in 25 Discharged COVID-19 Patients – Clinical Infectious Diseases

 

Related Commentary on Twitter

https://twitter.com/GermHunterMD/status/1247937913175695363

 


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