Family Medicine
Hydroxychloroquine and Chloroquine for Covid-19: Large Observational Analysis Finds No Benefit and Possible Harm
25 May, 2020 | 02:03h | UTCCommentaries: Chloroquine or hydroxychloroquine for COVID-19: why might they be hazardous? – The Lancet AND What a big new study on malaria drugs as Covid-19 treatments tells us — and what it doesn’t – STAT AND Hydroxychloroquine May Cause More Harm Than Benefit To COVID-19 Patients, Says New Lancet Study – Health Policy Watch
Opinion: Why Countries Should Stop Using Anti-malarial Drugs for COVID-19
25 May, 2020 | 02:02h | UTCWhy countries should stop using anti-malarial drugs for COVID-19 – The Conversation
[Preprint] Meta-Analysis: Susceptibility to and Transmission of COVID-19 Amongst Children and Adolescents Compared with Adults
25 May, 2020 | 01:52h | UTCCommentaries: Children appear half as likely to catch COVID-19 as adults – London School of Hygiene & Tropical Medicine AND Expert reaction to systematic review preprint looking at susceptibility to SARS-CoV-2 infection in children and adolescents compared with adults – Science Media Centre
Promising Early Results with New Vaccine from China in Phase I Trial
25 May, 2020 | 01:57h | UTCCommentaries: First human trial of COVID-19 vaccine finds it is safe and induces rapid immune response – The Lancet AND Early Study Of Covid-19 Vaccine Developed In China Sees Mixed Results – Forbes AND Coronavirus Vaccine Shows Promising Early Results in China – The New York Times AND A Chinese biotech just published the first human data for its coronavirus vaccine candidate, supporting further trials – Business Insider AND Experts skeptical after researchers report positive vaccine results – CNN AND Two COVID-19 Vaccine Candidates Induce Immune Response In Healthy Volunteers – Health Policy Watch
Study: 10 of 60 Patients Treated for COVID-19 Persisted with Positive RT-PCR Results from 4 to 24 Days After Hospital Discharge
25 May, 2020 | 01:50h | UTCCommentaries: Expert reaction to study on PCR testing results from 60 people after clinical recovery from COVID-19 – Science Media Centre AND 16% of recovered patients test positive for COVID-19 weeks after discharge: study – UPI
Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach
25 May, 2020 | 01:42h | UTC
Cohort Study: Fluconazole Use in the First Trimester of Pregnancy Linked to Increased Risk of Musculoskeletal Malformations
25 May, 2020 | 01:31h | UTCCommentary: Musculoskeletal Malformations Up With Fluconazole in Pregnancy – Physician’s Weekly
How Coronavirus Lockdowns Stopped Flu in its Tracks
22 May, 2020 | 04:53h | UTCHow coronavirus lockdowns stopped flu in its tracks – Nature
“Reported rates of influenza and other infections have fallen sharply, but some communicable diseases may see a rise.”
Olfactory Dysfunction in COVID-19: Diagnosis and Management
21 May, 2020 | 09:24h | UTCOlfactory Dysfunction in COVID-19: Diagnosis and Management – JAMA
Related: Loss of smell and taste as symptoms of COVID-19: what does the evidence say? – CEBM Oxford
COVID-19 in Children: Clinical Approach and Management
21 May, 2020 | 09:19h | UTCCOVID-19 in Children: Clinical Approach and Management – The Indian Journal of Pediatrics
Related Systematic Reviews: SARS-CoV-2 Infection in Children and Adolescents (study and commentaries) AND SARS-CoV-2 (COVID-19): What do we know about children? A systematic review – Clinical Infectious Diseases
Systematic Review: Safety and Adverse Effects of 80 Antidepressants, Antipsychotics, Anti‐attention‐deficit/hyperactivity Medications and Mood Stabilizers in Children and Adolescents
21 May, 2020 | 09:10h | UTC
[No Publication Available] Covid-19 Patients Testing Positive After Recovery Aren’t Infectious
20 May, 2020 | 10:00h | UTCCovid Patients Testing Positive After Recovery Aren’t Infectious, Study Shows – Bloomberg
Why Saliva Tests Could Offer a Better Alternative to Nasal COVID-19 Swabs
20 May, 2020 | 09:58h | UTCOriginal Article: Saliva—Friend and Foe in the COVID-19 Outbreak – Diagnostics
Editorial: Lack of Efficacy of Hydroxychloroquine in Covid-19
20 May, 2020 | 10:01h | UTCLack of efficacy of hydroxychloroquine in covid-19 – The BMJ
Original Research: Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial – The BMJ
Related Meta-analysis (preprint) Hydroxychloroquine in COVID-19: A systematic review and meta-analysis – medRxiv
Meta-Analysis: ACEI/ARB Use and Risk of Infection or Severity or Mortality of COVID-19
20 May, 2020 | 09:50h | UTCRelated Study (Preprint): Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease-19 – medRxiv
Meta-Analysis: Association of Blood Pressure Lowering with Incident Dementia or Cognitive Impairment
20 May, 2020 | 09:45h | UTCAssociation of Blood Pressure Lowering With Incident Dementia or Cognitive Impairment: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Commentary: Controlling blood pressure may reduce dementia risk by 7% – UPI
Should Azithromycin be Used to Treat COVID-19?
20 May, 2020 | 09:47h | UTCShould azithromycin be used to treat COVID-19? A rapid review – BJGP Open
Decline in Child Vaccination Coverage During the COVID-19 Pandemic
19 May, 2020 | 04:26h | UTCCommentaries: More evidence US childhood vaccinations are dropping amid coronavirus pandemic – CNN AND Michigan reports a sharp drop in child vaccinations after the CDC warned missed shots could lead to a measles resurgence across the US – Business Insider
Randomized Trial: No Benefit from Hydroxychloroquine in Patients with Mild to Moderate Covid-19
18 May, 2020 | 02:11h | UTCCommentary: Further evidence does not support hydroxychloroquine for patients with COVID-19 – BMJ
Risk factors for SARS-CoV-2 in a Primary Care Network
18 May, 2020 | 01:56h | UTCCommentaries: Who is most likely to be infected with SARS-CoV-2? – The Lancet Infectious Diseases AND Sociodemographic factors associated with a positive test for COVID-19 in primary care – The Lancet AND COVID-19 discriminates along racial, socioeconomic lines, study finds – UPI
Systematic Review: Risks and Impact of ACE Inhibitors or ARBs on SARS-CoV-2 Infection in Adults
18 May, 2020 | 01:47h | UTC
Study: Use of Renin–angiotensin–aldosterone System Inhibitors Does Not Increase the Risk of COVID-19 Requiring Admission to Hospital
18 May, 2020 | 01:45h | UTCCommentary: Hypertension, renin–angiotensin–aldosterone system inhibition, and COVID-19 – The Lancet
Description of an Outbreak of Severe Kawasaki-like Disease at the Italian Epicenter of the SARS-CoV-2 Epidemic
15 May, 2020 | 03:53h | UTCCommentaries: Kawasaki-like disease: emerging complication during the COVID-19 pandemic – The Lancet AND Kawasaki-like COVID-19 complication found in Italian kids – CIDRAP AND What we know about the new Covid-19-linked illness in children – Vox AND Coronavirus: Children affected by rare Kawasaki-like disease – BBC
Related: Case Series: Hyperinflammatory Shock in Children During COVID-19 Pandemic
Cochrane Library Review of Guidelines for Key Questions Relating to the Care of Pregnant Women and Their Babies
15 May, 2020 | 03:46h | UTC
Study: Airborne Lifetime of Small Speech Droplets and their Potential Importance in SARS-CoV-2 Transmission
15 May, 2020 | 03:43h | UTCCommentaries: Expert reaction to study looking at speech-generated droplets and COVID-19 transmission – Science Media Centre AND Loud Talking Can Spread More than 1,000 Coronavirus Particles in the Air for 14 Minutes: Study – The Science Times AND Simply talking in confined spaces may be enough to spread the coronavirus, researchers say – USA Today AND Loud talking could leave coronavirus in the air for up to 14 minutes – MIT Technology Review