Family Medicine
[Abstract Only] Meta-analysis: Effect of urate-lowering therapy on cardiovascular and kidney outcomes
20 Oct, 2020 | 01:22h | UTCEffect of Urate-Lowering Therapy on Cardiovascular and Kidney Outcomes: A Systematic Review and Meta-Analysis – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary on Twitter
Study found urate-lowering therapy didn't produce benefits on clinical outcomes including major adverse cardiovascular events, all-cause mortality & kidney failure. Insufficient evidence to support urate lowering to improve kidney & cardiovascular outcomes https://t.co/uifm4vikYe pic.twitter.com/3fV60V3Lcx
— CJASN (@CJASN) October 14, 2020
[Preprint] Multi-organ impairment in low-risk individuals with long COVID
18 Oct, 2020 | 23:18h | UTCMulti-organ impairment in low-risk individuals with long COVID – medRxiv
Related study (preprint): Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services – medRxiv
Commentary on Twitter
"In a young, low-risk population with ongoing symptoms, almost 70% of individuals have impairment in 1 or more organs 4 months after initial symptoms of #SARSCoV2 infection" #LongCovid https://t.co/gPnDtacI1J by @amibanerjee1 and colleagues
via @ahandvanish<-🙏 pic.twitter.com/7mKEsQgq5l— Eric Topol (@EricTopol) October 17, 2020
WHO: Herd immunity, lockdowns and COVID-19
18 Oct, 2020 | 23:19h | UTCCoronavirus disease (COVID-19): Herd immunity, lockdowns and COVID-19 – World Health Organization
Commentary on Twitter
Herd immunity is a concept used for vaccination, in which a population can be protected from a virus if a threshold of vaccination is reached. Vaccinated people are protected from getting the disease & passing it on, breaking any chains of transmission.
👉https://t.co/X9N7zcyfOX pic.twitter.com/V22iA6OqOq
— World Health Organization (WHO) (@WHO) October 16, 2020
New studies show reduced prevalence and severity of SARS-CoV-2 infection in ABO blood group O
18 Oct, 2020 | 23:16h | UTCStudy 1: Reduced prevalence of SARS-CoV-2 infection in ABO blood group O – Blood Advances
Commentaries: People with blood type O may have lower risk of Covid-19 infection and severe illness, two new studies suggest – CNN AND Studies offer new evidence for possible link between blood type and COVID-19 susceptibility – American Society of Hematology
Answering key questions about COVID-19 vaccines
18 Oct, 2020 | 23:10h | UTCAnswering Key Questions About COVID-19 Vaccines – JAMA
Commentary on Twitter
Many individuals are hesitant about receiving #COVID19 vaccines. It is critical that clinicians stay well informed about emerging data so that they can help patients make sound decisions https://t.co/1QDwOKuDqc @JesseGoodmanMD @ImmunizeOrg @pharmacists
— JAMA (@JAMA_current) October 16, 2020
NIHR dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid)
18 Oct, 2020 | 23:14h | UTCA dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid) – National Institute for Health Research
News Release: Living with COVID: NIHR publishes dynamic themed review into ‘ongoing COVID’
Commentaries: Coronavirus: ‘Long Covid could be four different syndromes’ – BBC AND Long covid could be four different syndromes, review suggests – The BMJ AND ‘Long COVID’ may affect multiple parts of body and mind, doctors say – Reuters
Randomized trial: Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women
18 Oct, 2020 | 23:06h | UTCCommentary: For Urinary Incontinence, No Need to Add Biofeedback to Pelvic Floor Exercises – NEJM Journal Watch
Commentary on Twitter
This RCT did not find a statistically significant or clinically important difference in severity of urinary incontinence between women randomised to electromyographic biofeedback plus pelvic floor muscle training or to pelvic floor muscle training alonehttps://t.co/z8nxLplT57
— The BMJ (@bmj_latest) October 17, 2020
Scientific consensus on the COVID-19 pandemic: we need to act now
16 Oct, 2020 | 09:41h | UTCScientific consensus on the COVID-19 pandemic: we need to act now – The Lancet
NEW Special issue of The Global Burden of Disease Study 2019
16 Oct, 2020 | 09:31h | UTCHomepage: Global Burden of Disease Study 2019 – The Lancet
Editorial: Global health: time for radical change? – The Lancet
Commentary on Twitter
NEW Special issue of #GBDStudy 2019: 286 causes of death, 369 diseases & injuries, 87 risk factors in 204 countries & territories—data reveal how the world’s population was prepared in terms of underlying health for #COVID19 pandemic https://t.co/Af7hOlLFoJ pic.twitter.com/9kSeyB77Fv
— The Lancet (@TheLancet) October 15, 2020
Life expectancy after bariatric surgery in the Swedish Obese Subjects Study
16 Oct, 2020 | 09:29h | UTCCommentary: Higher average life expectancy after obesity surgery – University of Gothenburg
Commentary on Twitter
https://twitter.com/NEJM/status/1316816109279084545
Systematic review: Management of colonic diverticulitis
16 Oct, 2020 | 09:25h | UTCManagement of Colonic Diverticulitis – Agency for Healthcare Research and Quality
Full report: Management of Colonic Diverticulitis
Evidence summary: Management of Colonic Diverticulitis
Study: Negative D-dimer safely rules out DVT as a stand-alone test
16 Oct, 2020 | 09:26h | UTCNegative D-dimer safely ruled out DVT as a stand-alone test – Blood Advances
Randomized trial: Effect of sustained smoking cessation counseling and free medication vs. shorter-term counseling and medication advice on smoking abstinence
16 Oct, 2020 | 09:23h | UTCCommentary: Long-term, frequent phone counseling helps cancer patients who smoke quit – eCancer
Review: Evaluation and treatment of patients with hypercortisolism
16 Oct, 2020 | 09:24h | UTCEvaluation and Treatment of Patients With Hypercortisolism: A Review – JAMA Surgery
IDSA Position Statement: “Herd immunity” is not an answer to a pandemic
15 Oct, 2020 | 09:31h | UTC“Herd Immunity” is Not an Answer to a Pandemic – Infectious Diseases Society of America
Commentary on Twitter
https://t.co/k15V8bMjiK via @IDSAInfo Excellent statement from @IDSAInfo & @HIVMA Presidents of why "herd immunity" is not an answer to a pandemic. These is the professional association representing > 12K specialists in infectious diseases so these are the real experts!
— Carlos del Rio (@CarlosdelRio7) October 14, 2020
Updated Cochrane Review shows electronic cigarettes can help people quit smoking
16 Oct, 2020 | 09:21h | UTCUpdated Cochrane Review shows electronic cigarettes can help people quit smoking – Cochrane Library
Original study: Electronic cigarettes for smoking cessation – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1316475634445672448
Review: The duration of infectiousness of individuals infected with SARS-CoV-2
15 Oct, 2020 | 09:26h | UTCThe duration of infectiousness of individuals infected with SARS-CoV-2 – Journal of Infection
Commentary on Twitter
🔥NEW Review🔥#COVID19 pts with mild-to-moderate illness are highly unlikely to be infectious beyond 10 ds from symptom onset , However, limited studies found that Immunocompromised and severe-to-critical patients may be infectious for >10 days https://t.co/hogXvFpPEb pic.twitter.com/fBm5Se4RBf
— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) October 13, 2020
Coronavirus vaccine: What we know so far – a comprehensive guide by academic experts
15 Oct, 2020 | 09:17h | UTC
WHO Global tuberculosis report 2020
15 Oct, 2020 | 09:35h | UTCGlobal tuberculosis report 2020 – World Health Organization
News release: WHO: Global TB progress at risk – World Health Organization
Executive summary: Global tuberculosis report 2020
Commentary: WHO warns of COVID impact on TB services – CIDRAP
Commentary on Twitter
The 🌏🌍🌏 has made steady progress in tackling tuberculosis (TB), with a 1⃣4⃣% drop in deaths between 2015 and 2019.
🚨 #COVID19 will lead to setbacks if no action is taken urgently, according to 🆕 WHO report 👉https://t.co/5BvbGjaudU pic.twitter.com/A4edYfyOBH
— World Health Organization (WHO) (@WHO) October 14, 2020
Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2020 Recommendations of the International Antiviral Society–USA Panel
15 Oct, 2020 | 09:13h | UTC
Commentary on Twitter
Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults https://t.co/J3zHm9rpkY via @JAMA_current The new @IAS_USA ART guidelines document is out. Enormous effort led by @msaagmd with @RMKGandhi @doc_in_a_box @drmt @PaulSaxMD @joseph_eron and others on panel.
— Carlos del Rio (@CarlosdelRio7) October 14, 2020
Podcast: Ten things every new doctor should know about drug reactions
15 Oct, 2020 | 09:02h | UTCTen Things Every New Doctor Should Know About Drug Reactions – JAMA
Study: Real-world blood pressure measurements vs. measurements taken in the SPRINT trial
15 Oct, 2020 | 09:00h | UTCCommentaries: A Tale of 2 Blood Pressures – JAMA Internal Medicine AND Real-World BP Measurements vs SPRINT Protocol – Physician’s Weekly
Commentary on Twitter
Incredibly important paper in @JAMAInternalMed demonstrating poor concordance between clinic blood pressure and trial based blood pressure. https://t.co/waLTYk9Lnu
— Stephen Juraschek MD, PhD, FAHA, AHSCP-CHS (@spjuraschek) October 13, 2020
Study: Polypharmacy (taking > 10 medications) is common in older patients with heart failure
15 Oct, 2020 | 09:03h | UTCPolypharmacy in Older Adults Hospitalized for Heart Failure – Circulation: Heart Failure
Commentaries: Ten or more medications, often prescribed to older heart failure patients, raises concerns – American Heart Association AND Polypharmacy Common Among Older Heart Failure Patients – Physician’s Weekly
Commentary on Twitter
New work from @OzanUnluMD @ParagGoyalMD indicates that polypharmacy (taking > 10 medications) is common in older patients with #heartfailure, and is primarily due to non-cardiovascular meds #AHAJournals @WeillCornell | https://t.co/hL0GZLaCnT pic.twitter.com/BHppxDQgor
— Circ: Heart Failure (@CircHF) October 13, 2020
Genomic evidence for reinfection with SARS-CoV-2: A case study
14 Oct, 2020 | 09:39h | UTCGenomic evidence for reinfection with SARS-CoV-2: a case study – The Lancet Infectious Diseases
Commentaries: First Case Of COVID-19 Reinfection In The US Confirmed; Exposure to Virus May Not Guarantee Protective Immunity, Says New Lancet Study – Health Policy Watch AND What reinfections mean for COVID-19 – The Lancet Infectious Diseases AND You can get reinfected with Covid-19 but still have immunity. Let’s explain. – Vox AND A 25-Year-Old Nevada Man Got COVID-19 Twice. Here’s What We Know—and Don’t Know—About Reinfection – TIME
Related: Dutch woman dies after catching Covid-19 twice, the first reported reinfection death – CNN
Johnson & Johnson Covid-19 vaccine study paused due to unexplained illness in participant
14 Oct, 2020 | 09:31h | UTCJohnson & Johnson Covid-19 vaccine study paused due to unexplained illness in participant – STAT
News Release: Johnson & Johnson Temporarily Pauses All Dosing in Our Janssen COVID-19 Vaccine Candidate Clinical Trials
Commentaries: Johnson & Johnson ‘Pauses’ COVID-19 Vaccine Trial Due To Unexplained Illness In Participant; Eli Lilly Reportedly Suspending Trial Of Antibody Treatment – Health Policy Watch AND Johnson & Johnson pauses Covid-19 vaccine trial after ‘unexplained illness’ – CNN