Family Medicine
Take whatever COVID vaccine you can get. All of them stop death and hospitalization
15 Feb, 2021 | 01:17h | UTCTake whatever COVID vaccine you can get. All of them stop death and hospitalization – USA Today
“All seven COVID-19 vaccines that have completed large efficacy trials — Pfizer, Moderna, Johnson & Johnson, Novavax, AstraZeneca, Sputnik V and Sinovac — appear to be 100% effective for serious complications. Not one vaccinated person has gotten sick enough to require hospitalization. Not a single vaccinated person has died of COVID-19.”
Small RCT: No effect from Zinc and Vitamin C supplementation among ambulatory patients with SARS-CoV-2 infection
15 Feb, 2021 | 01:20h | UTCCommentaries: Vitamin C, zinc don’t lessen Covid-19 symptoms, study finds – CNN AND Supplements for the Treatment of Mild COVID-19—Challenging Health Beliefs With Science From A to Z – JAMA Network Open AND Zinc, vitamin C show no effect for COVID-19 in small study – CIDRAP AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre
Commentary on Twitter
RCT finds high-dose zinc, ascorbic acid (vitamin C), or both, did not significantly decrease the duration of symptoms in ambulatory patients with #COVID19 vs standard of care. @DesaiMilindY @ClevelandClinic @ErinMichos @miguelcainzos23 #VisualAbstract https://t.co/ahcc2awJB8
— JAMA Network Open (@JAMANetworkOpen) February 12, 2021
Limited transmission of COVID-19 from open schools but teachers were affected: Swedish study
15 Feb, 2021 | 01:11h | UTCOriginal Study: The effects of school closures on SARS-CoV-2 among parents and teachers – Proceedings of the National Academy of Sciences
Commentary on Twitter
New data open vs closed schools from Sweden, and particularly the risk of #SARSCoV2 infections and hospitalizations among teachers, while low, doubled in upper-secondary. Parents: 17% increasehttps://t.co/y1N02xwLfc @PNASNews by @jonasvlachos @helenasvaleryd @UU_University
— Eric Topol (@EricTopol) February 11, 2021
CDC says it’s safe to reopen schools — with proper precautions
15 Feb, 2021 | 01:09h | UTCCDC says it’s safe to reopen schools — with proper precautions – Vox
See also: CDC Offers Clearest Guidance Yet For Reopening Schools – NPR
Guideline: Schools and Child Care Programs – Centers for Disease Control and Prevention
Increase aerosol transmission of Covid-19 with increased age and obesity
15 Feb, 2021 | 01:03h | UTCCommentary: Older, heavier adults possible ‘superspreaders’ of COVID-19, study finds – UPI AND Researchers unravel what makes someone a COVID-19 super-spreader – Tulane University
France’s health authority recommends single vaccine shot for people who have had COVID-19
15 Feb, 2021 | 01:02h | UTCFrance’s health authority recommends single vaccine shot for people who have had COVID-19 – Euronews
See also: Covid: France says just one jab needed for previously infected – BBC
Related: Covid-19: People who have had infection might only need one dose of mRNA vaccine – The BMJ AND You’ve had COVID: maybe one dose of vaccine is enough, studies suggest – MedicalXpress
Updated U.S. Recommended Adult Immunization Schedule
12 Feb, 2021 | 02:07h | UTCRecommended Adult Immunization Schedule, United States, 2021 – Annals of Internal Medicine
M-A: No link between blood pressure drugs and falls
12 Feb, 2021 | 02:05h | UTCNo link between blood pressure drugs and falls, finds study – University of Oxford
Original study: Association between antihypertensive treatment and adverse events: systematic review and meta-analysis – The BMJ
Commentary on Twitter (thread – click for more)
Can #bloodpressure treatment be harmful? Our new meta-analysis suggests it is NOT linked to #falls or #fractures but may increase the risk of syncope & acute kidney injury https://t.co/H5LlsFVBXJ – see thread @RichardJMcManus @Richard_D_Riley @ebhcmedstats @JulietU_S @drandyclegg pic.twitter.com/UtWjE1BzMW
— James Sheppard (@jamessheppard48) February 10, 2021
M-A: As consumer products, E-Cigarettes are not associated with increased smoking cessation, but may improve smoking cessation rates as a prescription therapy intervention
12 Feb, 2021 | 01:52h | UTCInvited Commentaries: E-Cigarettes: A Public Health Threat, Not a Population Health Intervention – American Journal of Public Health AND Reporting Certainty of Evidence on E-Cigarette Use for Adult Smoking Cessation – American Journal of Public Health AND Is Good Enough Good Enough? E-Cigarettes, Evidence, and Policy – American Journal of Public Health AND Should E-Cigarette Regulation Be Based on Randomized Trials or Observational Studies? – American Journal of Public Health AND
Related: Updated Cochrane Review shows electronic cigarettes can help people quit smoking – Cochrane Library
RCT: Delayed antibiotic prescription feasible for children with uncomplicated respiratory infections
12 Feb, 2021 | 02:02h | UTCDelayed Antibiotic Prescription for Children With Respiratory Infections: A Randomized Trial – Pediatrics (link to abstract – $ for full-text)
Commentary: Data support delayed antibiotics in kids with respiratory infections – CIDRAP
Cohort study: The use of macrolide antibiotics in pregnancy is not associated with an increased risk of major congenital malformations
12 Feb, 2021 | 02:04h | UTC
Study: New B.1.1.7 variant does not result in more severe disease in children compared to the original strain
12 Feb, 2021 | 02:23h | UTC
Commentary on Twitter
There were recent concerns and media reports that B.1.1.7 has more effects in children and young adults than the ancestral strain. Here are new data to provide reassurance that's not the case @LancetChildAdol https://t.co/85Dj4tl2qq pic.twitter.com/YmNOeOhpTB
— Eric Topol (@EricTopol) February 11, 2021
Video (6 min): A visual guide to the new coronavirus variants
12 Feb, 2021 | 02:20h | UTCA Visual Guide to the New Coronavirus Variants – Scientific American
[Preprint] Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
12 Feb, 2021 | 02:14h | UTCSix-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19 – medRxiv
Commentary: Covid linked to risk of mental illness and brain disorder, study suggests – The Guardian
Pediatric eye injuries by hydroalcoholic gel in the context of the Covid-19 Pandemic
12 Feb, 2021 | 02:12h | UTCCase series: Hand Sanitizer–Induced Ocular Injury: A COVID-19 Hazard in Children – JAMA Ophthalmology
Invited commentary: Unintended Consequences of Hand Sanitizer Use in the Coronavirus Disease 2019 Pandemic – JAMA Ophthalmology
Cohort study: First trimester prescription opioid use not associated with a substantial increase in risk for major congenital malformations
12 Feb, 2021 | 02:03h | UTC
RCT: Once-weekly, high-dose semaglutide is effective for improving overweight or obesity among non-diabetic adults
11 Feb, 2021 | 02:09h | UTCOnce-Weekly Semaglutide in Adults with Overweight or Obesity – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Semaglutide Plus Lifestyle Change Shown Effective for Obesity – NEJM Journal Watch
Commentary on Twitter
This double-blind study randomly assigned adults with obesity without diabetes to 68 weeks of once-weekly subcutaneous semaglutide or placebo, plus lifestyle intervention. Semaglutide therapy was associated with sustained, clinically relevant weight reduction.
— NEJM (@NEJM) February 10, 2021
Randomized, cross-over trial: Compared to Mediterranean diet, a Low-fat vegan diet is better at improving body weight, lipid concentrations, and insulin sensitivity
11 Feb, 2021 | 01:56h | UTC
Commentary on Twitter
36-week randomized cross-over trial:
💥Low-fat plant-based diet reduced body weight, fat mass, and visceral fat, increased insulin sensitivity, and improved blood lipids, compared with a Mediterranean diet.https://t.co/ROJX9WYcix
— Danielle Belardo, MD (@DBelardoMD) February 6, 2021
RCT: The effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults
11 Feb, 2021 | 01:58h | UTCThe effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial – The American Journal of Clinical Nutrition (link to abstract – $ for full-text)
Commentary on Twitter
Daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial https://t.co/sT81S8JfNs
No effect of protein supplementation in older persons, but lifting is good!
— Stuart Phillips (he/him) (@mackinprof) February 10, 2021
Meta-analysis: Chlorthalidone vs. hydrochlorothiazide
11 Feb, 2021 | 02:00h | UTCChlorthalidone versus hydrochlorothiazide: major cardiovascular events, blood pressure, left ventricular mass, and adverse effects – Journal of Hypertension (link to abstract – $ for full-text)
Commentary: Chlorthalidone Compared With HCTZ for MACE Reduction – Renal & Urology News
Red Yeast Rice for Hypercholesterolemia: JACC Focus Seminar
11 Feb, 2021 | 01:54h | UTC
CDC Guidance: Improve the fit and filtration of your mask to reduce the spread of COVID-19
11 Feb, 2021 | 02:21h | UTC
CDC study on practical ways for maximizing fit for masks to reduce SARS-CoV-2 transmission and exposure
11 Feb, 2021 | 02:25h | UTCCommentaries: CDC Says Double-Masking Offers More Protection Against The Coronavirus – NPR AND CDC report: Double-masking can block more than 90 percent of viral particles – NBC News
Small RCT: Inhaled budesonide reduces the need for hospitalization in COVID-19 patients
11 Feb, 2021 | 02:18h | UTCCommentaries: Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests – University of Oxford AND Expert reaction to preprint on an RCT of inhaled budesonide in the treatment of early COVID-19 – Science Media Centre
WHO experts recommend AstraZeneca COVID vaccine across all ages and countries
11 Feb, 2021 | 02:20h | UTCCommentaries: WHO Experts Recommend AstraZeneca COVID Vaccine Across All Ages & Countries – Signal For Start Of Global COVAX Vaccine Rollout – Health Policy Watch AND WHO backs use of Oxford/AstraZeneca Covid vaccine for adults of all ages – The Guardian AND Covid: WHO backs Oxford vaccine ‘even if variants present’ – BBC AND Expert reaction to WHO recommending use of the Oxford/AstraZeneca COVID-19 vaccine, including in over 65s – Science Media Centre AND Up Against Mutants, WHO Says AstraZeneca Vaccine Is Still A Good Bet – NPR