Family Medicine
Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
2 Apr, 2021 | 09:36h | UTCCommentary: If I’ve Had COVID-19, Do I Still Need Two Doses of Vaccine? – TIME AND The research is in: People who’ve already had COVID-19 need just one shot – Insider
Related: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary) AND Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2 – JAMA AND Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine – New England Journal of Medicine
Rapid point-of-care tests for diagnosing COVID-19 infection: the latest Cochrane evidence
2 Apr, 2021 | 09:21h | UTCOriginal review and commentaries: Systematic review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
Therapeutics and COVID-19 | WHO guideline update advises Ivermectin should only be used to treat COVID-19 within clinical trials
1 Apr, 2021 | 04:02h | UTCSummary and Infographic: Drug treatments for covid-19: living systematic review and network meta-analysis – The BMJ
Original guideline: Therapeutics and COVID-19: living guideline – World Health Organization
News release: WHO advises that ivermectin only be used to treat COVID-19 within clinical trials – World Health Organization
Commentary: WHO joins Europe, Merck in recommending against ivermectin for COVID-19 – Reuters
Commentary on Twitter
https://twitter.com/ThomasAgoritsas/status/1377372928451301384
M-A: Vitamin D supplementation to prevent acute respiratory infections
1 Apr, 2021 | 03:30h | UTCCommentaries: Vitamin D to prevent acute respiratory infections – The Lancet Diabetes & Endocrinology AND
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
1 Apr, 2021 | 03:32h | UTC
Commentaries on Twitter
https://twitter.com/Dr_WuJ/status/1376715405553590275
Salt substitution (70% sodium chloride/30% potassium chloride blend) is an effective, low-cost intervention for BP controlhttps://t.co/EemPEY9T2k pic.twitter.com/xVITnGLEip
— K Pavithran (@drkpavithran) March 31, 2021
Cohort study: Association of spontaneous abortion with all cause and cause specific premature mortality
1 Apr, 2021 | 03:27h | UTCCommentaries: Miscarriage linked to increased risk of early death – The BMJ AND Miscarriage Linked to Higher Risk for Premature Mortality – HealthDay
Commentary on Twitter
Study suggests spontaneous abortion is associated with a greater risk of premature death, particularly from cardiovascular disease. Spontaneous abortion could be an early marker of future health risk in women, including premature death, say the authorshttps://t.co/mA7IrF0J00
— The BMJ (@bmj_latest) March 28, 2021
Editorial | Vaccine certificates: does the end justify the means?
1 Apr, 2021 | 03:41h | UTCVaccine certificates: does the end justify the means? – The Lancet Microbe
Related: Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND “Vaccine Passport” Certification — Policy and Ethical Considerations – New England Journal of Medicine AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization
WHO: Sinopharm, Sinovac COVID-19 vaccine data show efficacy
1 Apr, 2021 | 03:58h | UTCSinopharm, Sinovac COVID-19 vaccine data show efficacy: WHO – Reuters
Commentary on Twitter
https://twitter.com/hildabast/status/1377377034180038659
AstraZeneca COVID vaccine 70% effective vs. B117 variant
1 Apr, 2021 | 03:55h | UTCAstraZeneca COVID vaccine 70% effective vs B117 variant – CIDRAP
Commentary on Twitter (thread – Click for more)
ASYMPTOMATIC & SYMPTOMATIC Efficacy of Oxford-AstraZeneca #COVID19 vaccine versus #B117 & non-B117 variants via 200k swabs in ~8500:🧵
Symptomatic #B117➡️ 70%
Asymptomatic #B117➡️ 29%
Other variants symptomatic➡️ 81.5%
Other variants asymptomatic➡️ 70%https://t.co/qSWYlHKP0g pic.twitter.com/gS7P9MCpyz
— Eric Feigl-Ding (@DrEricDing) March 31, 2021
[Press release – not published yet] Pfizer-BioNTech vaccine 100% effective against Covid-19 in adolescents
1 Apr, 2021 | 03:52h | UTCPress release: Pfizer-BioNTech Announce Positive Topline Results Of Pivotal Covid-19 Vaccine Study In Adolescents
Commentaries: The Pfizer-BioNTech Vaccine Is Said to Be Powerfully Protective in Adolescents – The New York Times AND Covid: Children ‘well protected by Pfizer vaccine’ – BBC AND Pfizer Says COVID-19 Vaccine Shows ‘100% Efficacy’ In Adolescents – NPR AND Pfizer says its COVID-19 vaccine protects younger teens – Associated Press AND Pfizer and BioNTech say vaccine prevents Covid-19 in adolescents – STAT
Commentaries on Twitter
https://twitter.com/hildabast/status/1377376427239075840
This is really terrific
In trial of 2260 adolescents 12-15 year of age, Pfizer vaccine highly effective at preventing infections
18 infections in placebo group
0 infections in vaccine group
Robust antibody response
No serious side-effects
Looking forward to @US_FDA review https://t.co/VymGXOVb5E
— Ashish K. Jha, MD, MPH (@ashishkjha) March 31, 2021
Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study
1 Apr, 2021 | 03:43h | UTC
Commentary on Twitter
Follow-up of nearly 48,000 hospitalized patients with covid-19 shows a high rate of readmission, death, and multi-organ disease (heart, diabetes, kidney, lung) compared with matched controls https://t.co/dzxVYdugz2 @bmj_latest pic.twitter.com/hWBn5w2XQf
— Eric Topol (@EricTopol) April 1, 2021
Bill Gates: 5 things you should know about variants
1 Apr, 2021 | 03:49h | UTC5 things you should know about variants – GatesNotes
Commentary on Twitter
Here are five things you should know if you want to understand how variants are (and aren’t) complicating the pandemic. https://t.co/rANiDcZynJ
— Bill Gates (@BillGates) March 31, 2021
Opinion | “Vaccine Passport” Certification — Policy and Ethical Considerations
1 Apr, 2021 | 03:40h | UTCRelated: Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND Vaccine certificates: does the end justify the means? – The Lancet Microbe AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization
Physical inactivity and non-communicable disease burden in low-income, middle-income and high-income countries
31 Mar, 2021 | 03:10h | UTCCommentaries: Physical inactivity is responsible for up to 8% of non-communicable diseases and deaths worldwide – British Medical Journal AND ‘Couch Potato’ Lifestyles Cause Up to 8% of Global Deaths: Study – HealthDay
Commentary on Twitter
The health implications of physical inactivity are truly a global issue with physical inactivity responsible for up to 8% of non-communicable diseases and deaths across the world, finds research published in @BJSM_BMJ https://t.co/hcHlmgW7C6
— BMJ Group (@bmj_company) March 30, 2021
Why indoor spaces are still prime COVID hotspots
31 Mar, 2021 | 03:35h | UTCWhy indoor spaces are still prime COVID hotspots – Nature
[Preprint] Single dose of AstraZeneca and Pfizer vaccines shows 62% efficacy for preventing disease and reduces viral load/transmissibility of SARS-CoV-2 in residents of Long-Term Care Facilities
31 Mar, 2021 | 03:38h | UTCCommentaries: Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents – NewsMedical AND Care home residents gain 62% protection from single dose of COVID-19 vaccine – University College London
Commentary on Twitter (thread – click for more)
https://twitter.com/sailorrooscout/status/1376512132318121990
Opinion | Covid-19 vaccine passports will harm sustainable development
31 Mar, 2021 | 03:31h | UTCCovid-19 vaccine passports will harm sustainable development – The BMJ Opinion
“Where you are born can predict how freely you will be able to travel for opportunity, education, and leisure. Being a citizen of certain countries grants people access to nearly the entire globe, whereas others face challenges just to legally leave the borders of the country they live in”
Opinion | Covid-19 vaccine passports and vaccine hesitancy: freedom or control?
31 Mar, 2021 | 03:29h | UTCCovid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion
“Recent debates around “vaccine passports,” or formal/mandatory certification of vaccination, point towards a potential widening societal divide between those who are vaccinated and those who are not.”
The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis
31 Mar, 2021 | 03:27h | UTC
AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk
30 Mar, 2021 | 03:08h | UTCNews Release: Six pregnancy complications are among red flags for heart disease later in life – American Heart Association
‘Real world’ study by CDC shows Pfizer and Moderna vaccines were 90% effective
30 Mar, 2021 | 03:27h | UTC‘Real world’ study by CDC shows Pfizer and Moderna vaccines were 90% effective – STAT
Commentary on Twitter (thread – Click for more)
https://twitter.com/hildabast/status/1376648088878608386
Study: mRNA vaccine is associated with decreased SARS-CoV-2 viral load in individuals with breakthrough infection, suggesting a role in suppressing onward transmission
30 Mar, 2021 | 03:25h | UTC
Commentaries on Twitter
https://twitter.com/nresearchnews/status/1376667763914240000
(Thread – Click for more)
New @NatureMedicine: The concern about asymptomatic transmission addressed in nearly 5,000 people after 1st dose of mRNA vaccine (~2 -5 wks). Viral load markedly reduced (high Ct). Supports vaccine effect for blocking or strongly reducing chance of spreadhttps://t.co/mmJmZPZfHK pic.twitter.com/0TTf4cFZed
— Eric Topol (@EricTopol) March 29, 2021
COVID associated with hearing loss, tinnitus and vertigo – new study confirms link
30 Mar, 2021 | 03:19h | UTCOriginal study: One year on: an updated systematic review of SARS-CoV-2, COVID-19 and audio-vestibular symptoms – International Journal of Audiology
Cochrane Library Editorial: Contested effects and chaotic policies: the 2020 story of (hydroxy) chloroquine for treating COVID‐19
28 Mar, 2021 | 22:55h | UTCCommentary and Infographic: Is chloroquine or hydroxychloroquine useful in treating people with COVID-19, or in preventing infection in people who have been exposed to the virus? – Cochrane Library
Original review: Chloroquine or hydroxychloroquine for prevention and treatment of COVID‐19 – Cochrane Library
Commentary on Twitter
New #VisualAbstract for the @Cochrane_IDG systematic review on #Chloroquine or #hydroxychloroquine for prevention and treatment of #COVID19 https://t.co/U7TnMzQTil Many thanks to @tylerdau & @cg_coleman from @EmoryMedicine pic.twitter.com/tlFKKa31E8
— The Cochrane Library (@CochraneLibrary) March 25, 2021
NICE Guideline Update: Cannabis-based medicinal products
28 Mar, 2021 | 22:24h | UTCCannabis-based medicinal products – National Institute for Health and Care Excellence