Family Medicine
M-A: Diagnostic performance of different sampling approaches for SARS-CoV-2 RT-PCR testing
20 Apr, 2021 | 06:09h | UTCCommentary: Beyond COVID-19—will self-sampling and testing become the norm? – The Lancet Infectious Diseases
Related Meta-analysis: Saliva and nasopharyngeal swab nucleic acid amplification have similar diagnostic accuracy for the detection of SARS-CoV-2 AND Saliva vs. nasopharyngeal swabs equally sensitive for Covid-19 diagnosis
COVID-19 dynamics after a national immunization program in Israel
20 Apr, 2021 | 06:06h | UTCCOVID-19 dynamics after a national immunization program in Israel – Nature Medicine
Commentary on Twitter
https://twitter.com/segal_eran/status/1384134124244406280
M-A: Prevalence of depression, anxiety and post-traumatic stress disorder in health care workers during the COVID-19 pandemic
20 Apr, 2021 | 06:00h | UTC
Ten scientific reasons in support of airborne transmission of SARS-CoV-2
18 Apr, 2021 | 21:51h | UTCTen scientific reasons in support of airborne transmission of SARS-CoV-2 – The Lancet
Animated Videos: Aerosols and making spaces safe – University of Oxford
Commentary on Twitter (thread – click for more)
Just out in @TheLancet what experts have said for a year
SARS-CoV2 spreads PRIMARILY via airborne route
Failure to act on this has hampered efforts to prevent spread of COVID
Thank you @trishgreenhalgh @linseymarr @kprather88 @j_g_allen, others who stuck to the evidence https://t.co/uuJcUIKWHE
— Ashish K. Jha, MD, MPH (@ashishkjha) April 16, 2021
2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult
18 Apr, 2021 | 21:24h | UTC
Commentary on Twitter
Check out the latest @SCC_CCS Guideline for the Management of Dyslipidemia for the Prevention of #Cardiovascular Disease!! https://t.co/ZKC7DrMIOq #HotOffThePress @ThanassoulisMD @ArdenBarry @DrNatDayan @RuthMcPherson12 @HeartDocRx @SCC_CCS_KT @SCC_CCS_CEO @SCC_CCS_Trainee pic.twitter.com/LZFbXNjztP
— CJC Journals (@CJCJournals) March 27, 2021
ESC Consensus Document: Personalized exercise prescription in the prevention and treatment of arterial hypertension
18 Apr, 2021 | 21:22h | UTCNews release: How to prevent and treat high blood pressure with exercise – European Society of Cardiology
Viewpoint | Implementing Measurement Science for Electronic Health Record Use – “Clinicians trained in patient care are locked into hours of screen time to complete mandatory clerical and documentation tasks, often unrelated to the quality of the care”
18 Apr, 2021 | 21:09h | UTCImplementing Measurement Science for Electronic Health Record Use – JAMA (free for a limited period)
Related: Opinion – “The EMR has changed the doctor-patient duet into a ménage-à-trois” (resources on the subject) AND Study: Association Between Perceived Electronic Health Record Usability and Professional Burnout (study and commentaries) AND The future of electronic health records – Nature
Commentaries on Twitter
To optimize #EHR design, implementation, and regulation, EHR use measures must be developed that are trustworthy, clinically important, scientifically sound, transparent, and feasible for implementation.
A recent paper by @JAMA_current @JAMANetwork https://t.co/IN3ZxcON9m pic.twitter.com/kOVQGI1OGl
— Eugenio Santoro (@eugeniosantoro) April 11, 2021
"Drawing attention to the EHR user experience with empirical measurements could add visibility and transparency to what is happening—the hours wasted and the risks incurred—that could stimulate usability improvements." https://t.co/WCzuo288Bp
— Janos Kalman (@kalman_jl) April 9, 2021
China’s Sinovac COVID-19 vaccine 67% effective in preventing symptomatic infection, 85% effective in preventing hospitalizations and 80% effective in preventing deaths – Chile govt report
18 Apr, 2021 | 21:45h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/hildabast/status/1383183542495039490
A guideline to limit indoor airborne transmission of COVID-19
18 Apr, 2021 | 21:47h | UTC
Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission
18 Apr, 2021 | 21:49h | UTCIndoor Air Changes and Potential Implications for SARS-CoV-2 Transmission – JAMA
Commentary on Twitter (thread – click for more)
https://twitter.com/j_g_allen/status/1383073549380882438
Editorial: SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – “The very low prevalence of this complication of vaccination, however severe, relative to the benefits of preventing Covid-19 must be emphasized”
18 Apr, 2021 | 21:42h | UTCSARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – New England Journal of Medicine
COVID vaccines and blood clots: five key questions
18 Apr, 2021 | 21:40h | UTCCOVID vaccines and blood clots: five key questions – Nature
See also (podcast): Coronapod: could COVID vaccines cause blood clots? Here’s what the science says – Nature
Study shows past COVID-19 infection doesn’t fully protect young people against reinfection
18 Apr, 2021 | 21:35h | UTCOriginal study: SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study – The Lancet Respiratory Medicine
Commentary on Twitter
Risk of covid reinfection in a prospective study of >3,000 Marine recruits
Prior covid: 82% reduced compared w/ no prior covid (+ when reinfections occurred, much less viral loads)
Protection correlated w/ higher spike IgG antibody levels https://t.co/7Jl154lwDX @LancetRespirMed pic.twitter.com/xKVLKm8AA6— Eric Topol (@EricTopol) April 15, 2021
Study: Double masking improves protection from Covid-19 mostly by eliminating any gaps or poor-fitting areas of a mask
18 Apr, 2021 | 21:37h | UTCFitted Filtration Efficiency of Double Masking During the COVID-19 Pandemic – JAMA Internal Medicine
Commentaries: Fit matters most when double masking to protect yourself from COVID-19 – University of North Carolina Health Care AND Check your fit on that double mask if you want it to work against Covid, study says – CNN
Case report: Energy drink-induced cardiomyopathy
18 Apr, 2021 | 21:00h | UTCEnergy drink-induced cardiomyopathy – BMJ Case Reports
Commentaries: Student’s heart failure linked to ‘excessive’ energy drinks – BBC AND Heavy energy drink consumption linked to heart failure in a young man – BMJ
Study shows antihistamines may impair response to exercise training
16 Apr, 2021 | 06:06h | UTCCommentary: Histamine-suppressing drugs found to reduce benefits of exercise – MedicalXpress
Commentary on Twitter (thread – click for more)
Extremely excited to finally share our newest paper: Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans. Published today in @ScienceAdvances. A thread: (1/12)https://t.co/R4FNiKWyG9 pic.twitter.com/U2HFHOY9eA
— Thibaux Van der Stede (@ThibauxV) April 14, 2021
[Preprint] Risk of rare blood clotting much higher for COVID-19 than for vaccines
16 Apr, 2021 | 06:37h | UTCNews release: Risk of rare blood clotting higher for COVID-19 than for vaccines – University of Oxford
Original study (preprint): Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine
Commentaries: Brain clots ‘more likely’ with Covid infection than vaccine – BBC AND Risk for Cerebral Venous Thrombosis Elevated After COVID-19 Diagnosis – NEJM Journal Watch AND Study: COVID much more likely than vaccines to cause blood clots – CIDRAP
Commentary on Twitter
There is an interesting new preprint out that will probably generate a lot of coverage at least in the UK. Essentially it argues that the risk of CVST is much higher from #covid19 than from vaccines.
Quick thread on this:https://t.co/0MdDU2z9bp— Kai Kupferschmidt (@kakape) April 15, 2021
M-A: Treatment with hydroxychloroquine is associated with increased mortality in COVID-19 patients
16 Apr, 2021 | 06:30h | UTC
Commentaries on Twitter
The use of hydroxychloroquine in COVID19 will be remembered as one of the worst examples of medicine going against its core principle:
First Do No Harm. https://t.co/PGq4D5pJ1H— Maurizio Cecconi (@DrMCecconi) April 15, 2021
What collaboration can achieve
Just out in @NatureComms our meta-analysis of 14 unpublished & 14 published RCTs on Hydroxychloroquine/ Choloroquine
Thanks so much to the great team – and special thanks for rapidly sharing the data of unpublished trials!https://t.co/Dg1DmAx1Kq
— Lars G. Hemkens (@LGHemkens) April 15, 2021
Perspective | Ivermectin is the new Hydroxychorloquine
16 Apr, 2021 | 06:28h | UTCIvermectin is the new Hydroxychorloquine – Science-Based Medicine
Video | Coronavirus variants: What you need to know
16 Apr, 2021 | 06:32h | UTCCoronavirus variants: What you need to know – Nature Video
Editorial: Covid-19 has redefined airborne transmission
16 Apr, 2021 | 06:26h | UTCCovid-19 has redefined airborne transmission – The BMJ
Commentaries: Future attempts to reduce Covid-19 spread should focus on tackling airborne transmission – News Medical AND Open the windows to curb COVID spread: experts – MedicalXpress
Related: CDC Updated Guidance: “It is possible for people to be infected through contact with contaminated surfaces or objects, but the risk is generally considered to be low” (CDC Guidance and more) AND Deep Cleaning Isn’t a Victimless Crime – The Atlantic
Vaccines alone will not stop Covid spreading – here’s why (visual guide to the “Swiss cheese model”)
15 Apr, 2021 | 06:53h | UTCVaccines alone will not stop Covid spreading – here’s why – BBC
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – “we estimate that P.1 may be 1.7–2.4-fold more transmissible”
15 Apr, 2021 | 07:09h | UTCGenomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science
Commentary: The P.1 coronavirus variant is twice as transmissible as earlier strains – ScienceNews
Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient
15 Apr, 2021 | 06:51h | UTCPandemic Boosts an Old Idea—Bringing Acute Care to the Patient – JAMA
Related studies: Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates AND Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences – JAMA Internal Medicine
Ulcerative colitis: an update
15 Apr, 2021 | 06:16h | UTCUlcerative colitis: an update – Clinical Medicine Journal