Family Medicine
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome
29 Apr, 2021 | 08:31h | UTCBritish Society of Gastroenterology guidelines on the management of irritable bowel syndrome – Gut
Commentary on Twitter (thread – click for more)
Here are the new @BritSocGastro guidelines for #IBS in @Gut_BMJ! I'll summarize in 🧵 ⬇️⬇️⬇️!
😖💩🦠🧠🥦🍞💊#GITwitter #GI #gut #braingut #motility #DGBI #FGID #microbiome #probiotics #MedTwitter #MedEd https://t.co/zbXoPbKgHO
— John Damianos, M.D. (@john_damianosMD) April 26, 2021
AHA Scientific Statement: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormonal therapies
29 Apr, 2021 | 08:33h | UTCNews release: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormones – American Heart Association
Top Things to Know: Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System – American Heart Association
Commentaries: Hormonal Therapy for Breast and Prostate Cancer: Lessons and Opportunities – American Heart Association AND Hormonal Based Therapies in the Treatment of Breast and Prostate Cancer – balancing the risks! – American Heart Association AND Hormone Cancer Therapies Increase CV Risk: AHA Scientific Statement – TCTMD AND Closely Monitor Heart Health in Cancer Patients Who Get Hormonal Therapies: AHA – HealthDay
Review: Non-alcoholic fatty liver disease
29 Apr, 2021 | 08:30h | UTCNon-alcoholic fatty liver disease – The Lancet (free for a limited period)
Review: Systemic and organ-specific immune-related manifestations of COVID-19 – over 70 different systemic and organ-specific immune-related disorders have been reported
28 Apr, 2021 | 08:42h | UTCSystemic and organ-specific immune-related manifestations of COVID-19 – Nature Reviews Rheumatology
Pre-post study: A hospital quality improvement intervention significantly reduced the rates of cesarean delivery for nulliparous, term, singleton, vertex births
29 Apr, 2021 | 08:21h | UTCHospital Quality Improvement Interventions, Statewide Policy Initiatives, and Rates of Cesarean Delivery for Nulliparous, Term, Singleton, Vertex Births in California – JAMA (free for a limited period)
Editorial: Initiatives to Reduce Cesarean Delivery Rates for Low-risk First Births – JAMA
Commentary on Twitter (thread – click for more)
"Rates of cesarean delivery for NTSV births in California decreased [from 26% to 22.8%] in the setting of a coordinated hospital-level collaborative and statewide initiatives designed to support vaginal birth.
"The rest of the US had no change."https://t.co/jwKkQZ4nix @cmqcc
— Ben Harder #BlackLivesMatter (@benharder) April 27, 2021
CDC says fully vaccinated Americans can go outside without masks – but masks still needed in crowds
28 Apr, 2021 | 08:44h | UTCCDC Guidance: Choosing Safer Activities – Centers for Disease Control and Prevention
Commentaries: CDC: If You’re Vaccinated, You Don’t Need To Mask Outdoors (Unless You’re In A Crowd) – NPR AND CDC: Fully vaccinated Americans can go maskless outdoors – CIDRAP
Commentary on Twitter (thread – click for more)
If you are fully vaccinated against #COVID19, you can start doing many things that you had stopped doing because of the pandemic. If you haven’t been vaccinated yet, get a vaccine as soon as you can. See full details: https://t.co/s5kXwg65fB pic.twitter.com/fvhehUiiCi
— CDC (@CDCgov) April 27, 2021
USPSTF Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement – diagnostic confirmation with blood pressure measurements outside of the clinical setting is advised before starting treatment
28 Apr, 2021 | 08:16h | UTCEvidence Report: Screening for Hypertension in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Author Interview: USPSTF Recommendation: Screening for Hypertension in Adults
Editorials: The USPSTF Recommendation on Blood Pressure Screening: Making 2021 the Transformative Year in Controlling Hypertension AND USPSTF Recommendation Statement on Hypertension Screening in Adults—Where Do We Go From Here? – JAMA Network Open AND Will the 2021 USPSTF Hypertension Screening Recommendation Decrease or Worsen Racial/Ethnic Disparities in Blood Pressure Control? – JAMA Network Open AND USPSTF Recommendations for Screening for Hypertension in Adults: It Is Time to Unmask Hypertensive Risk – JAMA Cardiology
JAMA Patient Page: Screening for Hypertension in Adults
NICE publishes updated clinical guideline on the diagnosis and management of atrial fibrillation
27 Apr, 2021 | 09:33h | UTCGuideline: Atrial fibrillation: diagnosis and management – National Institute for Health and Care Excellence
M-A: Helicobacter pylori eradication therapy to prevent gastric cancer – H. pylori eradication may reduce the incidence of gastric cancer in healthy individuals in East Asian countries
27 Apr, 2021 | 09:21h | UTCHelicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis (link to abstract – $ for full-text – free article here)
Immunization services begin slow recovery from COVID-19 disruptions, though millions of children remain at risk from deadly diseases – WHO, UNICEF, Gavi
27 Apr, 2021 | 08:41h | UTCRelated report: Disability considerations for COVID-19 vaccination: WHO and UNICEF policy brief, 19 April 2021 – World Health Organization
Commentary on Twitter
While immunization services begin slow recovery from #COVID19, millions of children around the 🌍🌏🌎 remain vulnerable to deadly diseases.
More info 👉https://t.co/YjskC8z6nc pic.twitter.com/SEv8d2VSAB
— World Health Organization (WHO) (@WHO) April 26, 2021
Study in nursing homes shows rapid antigen testing could be a useful tool to identify contagious people at risk for transmitting SARS-CoV-2
27 Apr, 2021 | 08:35h | UTCEditorial: Utility of Rapid Antigen Tests in Nursing Homes
Commentary on Twitter
💥🆕 Despite lower positive agreement compared with RT-PCR, antigen test positivity had higher agreement with shedding of replication-competent virus. These results suggest that antigen testing could be a useful tool to rapidly identify contagious people. https://t.co/Dlw7ttLlSL pic.twitter.com/sGmfVIy02H
— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 26, 2021
M-A: Prophylaxis against Covid-19: 1 – no benefit from Hydroxychloroquine; 2 – as studies on ivermectin so far have been small, it remains very uncertain whether ivermectin reduces SARS-CoV-2 infection
27 Apr, 2021 | 08:44h | UTCProphylaxis against covid-19: living systematic review and network meta-analysis – The BMJ
Opinion | Real-world data, not predictions, should drive decisions on Covid-19 and school opening
27 Apr, 2021 | 08:26h | UTCReal-world data, not predictions, should drive decisions on Covid-19 and school opening – STAT
Commentary from the author on Twitter
Real-world data, not predictions, should drive decisions on Covid-19 and school opening with @elbeezuchdt @citizen_oregon: Concept is simple. Schools are half/closed due to alarmist inaccurate models. Use real-world data to drive our decisions on kids.https://t.co/HfZl8IAVXq
— Monica Gandhi MD, MPH (@MonicaGandhi9) April 23, 2021
Recommendations to address patients fear of adverse effects and COVID-19 vaccine hesitancy
25 Apr, 2021 | 21:58h | UTC
U.S. lifts pause on use of J&J’s Covid-19 vaccine
25 Apr, 2021 | 21:57h | UTCU.S. lifts pause on use of J&J’s Covid-19 vaccine – STAT
See also: CDC, FDA lift pause on using J&J’s coronavirus vaccine, add safety warning – CNN AND ACIP opts to lift pause on Johnson & Johnson vaccine – CIDRAP
Opinion | What it Means to be a Medical Conservative
25 Apr, 2021 | 21:06h | UTCWhat it Means to be a Medical Conservative – Stop and Think
RCT: Metformin vs. insulin in gestational diabetes – metformin was associated better glycemic control, lower risk of hypoglycemia, and less maternal weight gain
25 Apr, 2021 | 21:03h | UTCMeDiGes Study. Metformin versus insulin in gestational diabetes: Glycemic control, and obstetrical and perinatal outcomes. Randomized prospective trial. – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Related: Randomized trial tests metformin in women with type 2 diabetes in pregnancy AND Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis – PLOS Medicine AND Case-Control Study: Metformin Exposure in First Trimester of Pregnancy is Not Associated with Congenital Anomalies
Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized
23 Apr, 2021 | 08:48h | UTCHigh-dimensional characterization of post-acute sequalae of COVID-19 – Nature
Commentary on Twitter (thread – click for more)
Happy to share the latest paper from our team in @nature
A comprehensive characterization of post acute sequelae of COVID-19#longcovid #PASChttps://t.co/AGLnYCamWe@VAResearch @vahsrd @WUSTL @WUSTLpubhealth @WUSTLmed @WUSTLnews @VREFSTL @Biostayan @BCBowe
— Ziyad Al-Aly, MD (@zalaly) April 22, 2021
Guideline: Diagnosis and Treatment of Endometriosis
25 Apr, 2021 | 20:46h | UTC
Guideline: Vulvovaginal Candidosis (Excluding Mucocutaneous Candidosis)
25 Apr, 2021 | 20:47h | UTC
NIH Updates COVID-19 Treatment Guidelines – adds recommendations on colchicine, fluvoxamine, and monoclonal antibodies
23 Apr, 2021 | 08:46h | UTCNIH Coronavirus Disease 2019 (COVID-19)
Treatment Guidelines – National Institutes of Health
RCT: COVID outpatients don’t benefit from hydroxychloroquine, lopinavir-ritonavir
23 Apr, 2021 | 08:42h | UTCCOVID outpatients don’t benefit from hydroxychloroquine, lopinavir-ritonavir – CIDRAP
Commentary on Twitter (thread – Click for more)
1/ No benefit from Hydroxychloroquine or Lopinavir-Ritonavir on Hospitalization/Viral clearance for COVID-19 https://t.co/yhXxv26418 via @JAMANetworkOpen part of @JAMANetwork
— Priya Sampathkumar (@PSampathkumarMD) April 22, 2021
Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19
23 Apr, 2021 | 08:39h | UTC
Commentary on Twitter
A 💥🆕 case series highlights that adults 50 years or younger with asymptomatic COVID-19 infection diagnosed by positive SARS-CoV-2 serological test result may present with ischemic stroke during the convalescent phase of the infection
https://t.co/BVlo7Z1hgn @JAMANetworkOpen— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 22, 2021
Covid-19: More data on the increased risks to pregnant women and their newborn infants
23 Apr, 2021 | 08:44h | UTCEditorial: COVID-19 in Pregnant Women and Their Newborn Infants
Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN
Commentary on Twitter
18 country study in >2000 pregnant women with and without #COVID19 shows higher complication and death rates in symptomatic, but not asymptomatic, women with COVID-19. Their babies were at greater risk of neonatal complications, mainly due to preterm birth https://t.co/mRl8OOIMsz
— JAMA Pediatrics (@JAMAPediatrics) April 22, 2021
RCT: Single-Dose Johnson & Johnson Vaccine has 85% efficacy against severe/critical Covid-19 and maintains efficacy against variant B.1.351
22 Apr, 2021 | 08:50h | UTC