Evidence-based Medicine
Review: Overdiagnosis in Primary Care
17 Aug, 2018 | 02:10h | UTCState of the Art Review: Overdiagnosis in primary care: framing the problem and finding solutions – The BMJ (free for two weeks)
Perspective: 5 Steps to Unpack a Randomized Trial
17 Aug, 2018 | 02:03h | UTCYoga, Depression, & Clinical Trial Critique 101 – Hilda Bastian, in Absolutely Maybe Blog (free)
“5 steps to unpack a randomized trial!” (via @hildabast, see Tweet)
Perspective: Surrogate End Points Ain’t all that Bad
17 Aug, 2018 | 01:45h | UTCSurrogate End Points Ain’t all that Bad – The Health Care Blog (free) (via @RogueRad)
Clinical Practice Guidelines: What’s Next?
11 Aug, 2018 | 03:22h | UTCClinical Practice Guidelines: What’s Next? – JAMA (free for a limited period)
Perspective: Addressing Barriers to Inclusion of Pregnant Women in Clinical Trials
11 Aug, 2018 | 03:02h | UTCAddressing Barriers to Inclusion of Pregnant Women in Clinical Trials – JAMA (free for a limited period)
Publication Bias: The Answer to Your Research Question May be Sitting in Somebody’s File Drawer
11 Aug, 2018 | 03:02h | UTCRelated: Bias in medical research: A glossary of common research biases – First10Em (free) Catalogue of Bias – Centre for Evidence-Based Medicine, University of Oxford (free)
Opinion: Anti-Vaccine Activists Have Taken Vaccine Science Hostage
11 Aug, 2018 | 02:16h | UTCAnti-Vaccine Activists Have Taken Vaccine Science Hostage – The New York Times (10 articles per month are free)
“Should researchers not publish findings when there’s a chance they might be misinterpreted and scare the public?” (via @NYTHealth see Tweet)
Bias in Medical Research: A Glossary of Common Research Biases
11 Aug, 2018 | 02:05h | UTCBias in medical research: A glossary of common research biases – First10Em (free) (via @pash22)
Related: Catalogue of Bias – Centre for Evidence-Based Medicine, University of Oxford (free)
Perspective: Europe Expanded the “No Elsevier Deal” Zone & This Could Change Everything
3 Aug, 2018 | 11:33h | UTC
AAFP Guideline: PSA-Based Prostate Cancer Screening in Men Aged 55-69
3 Aug, 2018 | 04:07h | UTCPSA-Based Prostate Cancer Screening in Men Aged 55-69 – American Academy of Family Physicians (free)
News Release: AAFP Updates Its PSA Screening Recommendation (free)
Related Guidelines with conflicting viewpoints: American Cancer Society Guideline for the Early Detection of Prostate Cancer (free) AND USPSTF Recommendation Statement: Screening for Prostate Cancer (free guideline, editorial and commentaries)
Richard Lehman’s Journal Reviews, 30 July 2018
3 Aug, 2018 | 04:04h | UTCRichard Lehman’s journal reviews, 30 July 2018 – The BMJ Opinion (free)
Richard Lehman’s final review of the latest research in the top medical journals.
Richard Lehman’s journal reviews – 23 July 2018
26 Jul, 2018 | 18:04h | UTCRichard Lehman’s journal reviews, 23 July 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
BMJ Series: Strengthening Research for Health in the Americas
20 Jul, 2018 | 03:21h | UTCSeries: Strengthening Research for health in the Americas – The BMJ (free articles)
Editorial: Research for health in the Americas (free)
Perspective: Contrary to Common Belief, Randomized Controlled Trials Inevitably Produce Biased Results
20 Jul, 2018 | 03:02h | UTCOriginal Article: Why all randomised controlled trials produce biased results – Annals of Medicine (free)
Source: Nature Briefing Newsletter
Study: Clinical Trial Evidence Supporting FDA Approval of Drugs Granted Breakthrough Therapy Designation
20 Jul, 2018 | 02:50h | UTCClinical Trial Evidence Supporting FDA Approval of Drugs Granted Breakthrough Therapy Designation – JAMA (link to abstract – $ for full-text)
Commentaries: Are ‘breakthrough’ drugs as safe as other FDA-approved medicines? – CNN (free) AND Evidence to support ‘breakthrough’ drugs often very limited: study – Reuters (free)
Report – Open Science by Design: Realizing a Vision for 21st Century Research
20 Jul, 2018 | 02:51h | UTCNews Release: Report Proposes Recommendations and New Framework to Speed Progress Toward Open Science (free)
Head To Head: Does Evidence Based Medicine Adversely Affect Clinical Judgment?
20 Jul, 2018 | 02:49h | UTCDoes evidence based medicine adversely affect clinical judgment? – The BMJ (free) (via @michelaccad)
Systematic Review: Harms Reporting in Trials with Probiotics
20 Jul, 2018 | 02:48h | UTCHarms Reporting in Randomized Controlled Trials of Interventions Aimed at Modifying Microbiota: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Reporting on risks often inadequate for prebiotics, probiotics, synbiotics – ACP Internist (free) AND Probiotics studies often don’t disclose safety data or risks, report finds – STAT (free) AND Safety of Probiotic Supplements Is Not Guaranteed, Study Says – Consumer Reports (free)
“How to make an intervention safe? Don’t report the adverse events”. (via @EricTopol see Tweet)
Richard Lehman’s Journal Review – 16 July 2018
20 Jul, 2018 | 02:28h | UTCRichard Lehman’s journal review, 16 July 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Last Month in Oncology with Dr. Bishal Gyawali
13 Jul, 2018 | 03:01h | UTCLast Month in Oncology with Dr. Bishal Gyawali: June 2018 – eCancer News (free)
This review has an interesting opinion on changing definitions of clinically meaningful endpoints in cancer research.
Review: Reading Mendelian Randomization Studies
13 Jul, 2018 | 03:00h | UTCResearch Methods & Reporting: Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians – The BMJ (free)
Consensus Report: Returning Individual Research Results to Participants
13 Jul, 2018 | 02:38h | UTCCommentaries: National Academies panel urges researchers to routinely share test results with study participants – STAT (free) AND If you give your DNA and tissues to science, should you get a peek at what they might contain? – Science (free) AND New report says individual research results should be shared with participants more often – National Academies of Sciences, Engineering, and Medicine, via EurekAlert (free)
Related Viewpoint: Return of Research Results to Study Participants: Uncharted and Untested – JAMA (free for a limited period)
Richard Lehman’s journal review – 9 July 2018
13 Jul, 2018 | 02:34h | UTCRichard Lehman’s journal review, 9 July 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals
Sharing Science at Today’s Pace: An Experience with Preprints
13 Jul, 2018 | 01:47h | UTCSharing science at today’s pace: an experience with preprints – The BMJ Opinion (free)
Perspective: Can We Science Our Way out of the Reproducibility Crisis?
13 Jul, 2018 | 01:14h | UTCCan We Science Our Way out of the Reproducibility Crisis? – Absolutely Maybe Blog (free)