Evidence-based Medicine
Covid-19 vaccine protocols reveal that trials are designed to succeed
20 Oct, 2020 | 01:40h | UTCCovid-19 Vaccine Protocols Reveal That Trials Are Designed To Succeed – Forbes
‘No evidence of effect’ versus ‘evidence of no effect’: how do they differ?
20 Oct, 2020 | 01:28h | UTC
Commentary on Twitter
What is the difference between ‘no evidence of effect’ vs ‘evidence of no effect’? @Elpida_Vnz discusses this important concept in a @Students4BE blog: https://t.co/0CCSclr0lH “Absence of evidence is not evidence of absence”.
— Cochrane (@cochranecollab) October 16, 2020
New PLOS pricing test could signal end of scientists paying to publish free papers
18 Oct, 2020 | 23:02h | UTCNew PLOS pricing test could signal end of scientists paying to publish free papers – Science
Viewpoint: Sensible medicine—balancing intervention and inaction during the COVID-19 pandemic
16 Oct, 2020 | 09:38h | UTCSensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic – JAMA
Author interview: Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic
Commentary on Twitter
https://twitter.com/seymoc/status/1316765788523511809
Researchers worldwide fight to work and teach amid COVID-19
16 Oct, 2020 | 09:35h | UTCResearchers worldwide fight to work and teach amid COVID-19 – Nature
Study: Real-world blood pressure measurements vs. measurements taken in the SPRINT trial
15 Oct, 2020 | 09:00h | UTCCommentaries: A Tale of 2 Blood Pressures – JAMA Internal Medicine AND Real-World BP Measurements vs SPRINT Protocol – Physician’s Weekly
Commentary on Twitter
Incredibly important paper in @JAMAInternalMed demonstrating poor concordance between clinic blood pressure and trial based blood pressure. https://t.co/waLTYk9Lnu
— Stephen Juraschek MD, PhD, FAHA, AHSCP-CHS (@spjuraschek) October 13, 2020
Perspective: Why does a high-impact publication matter so much for a career in research?
15 Oct, 2020 | 08:56h | UTCWhy does a high-impact publication matter so much for a career in research? – Nature
Research integrity: Nine ways to move from talk to walk
13 Oct, 2020 | 01:01h | UTCResearch integrity: nine ways to move from talk to walk – Nature
Initiative pushes to make journal abstracts free to read in one place
13 Oct, 2020 | 01:00h | UTCInitiative pushes to make journal abstracts free to read in one place – Nature
Researchers face hurdles to evaluate, synthesize COVID-19 evidence at top speed
12 Oct, 2020 | 00:37h | UTCResearchers face hurdles to evaluate, synthesize COVID-19 evidence at top speed – Science
Three lessons COVID-19 has taught us about Open Access publishing
7 Oct, 2020 | 09:19h | UTC
John P.A. Ioannidis: Scientific petitions and open letters in the Covid-19 era
4 Oct, 2020 | 23:27h | UTCJohn P.A. Ioannidis: Scientific petitions and open letters in the covid-19 era – The BMJ Opinion
India pushes bold ‘one nation, one subscription’ journal-access plan
2 Oct, 2020 | 09:10h | UTCIndia pushes bold ‘one nation, one subscription’ journal-access plan – Nature
HHMI, one of the largest research philanthropies, will require immediate open access to papers
2 Oct, 2020 | 09:09h | UTCRelated: UC Terminates Subscriptions with World’s Largest Scientific Publisher in Push for Open Access (several resources on the subject)
New research shows older adults are still often excluded from clinical trials
1 Oct, 2020 | 09:02h | UTCNew research shows older adults are still often excluded from clinical trials – STAT
Original Study: The Exclusion of Older Persons From Vaccine and Treatment Trials for Coronavirus Disease 2019—Missing the Target – JAMA Internal Medicine
Commentary on Twitter
“It is important we have a trial population that reflects the real-world population." https://t.co/tRpo0NGL5x
— STAT (@statnews) October 1, 2020
Personal experiences or anecdotes (stories) are an unreliable basis for assessing the effects of most treatments
28 Sep, 2020 | 01:24h | UTC
Commentary on Twitter
‘It ain’t so much the things we don’t know that get us into trouble. It’s the things we know that just ain’t so.’ – Anon. https://t.co/8vyoayvyZ7 In this @CochraneUK blog, @elainefin4 of @iHealthFacts1 explains why personal experiences, or anecdotes, are unreliable evidence. pic.twitter.com/PqHrnGPvSM
— Students4BE (@Students4BE) September 27, 2020
Harvard University says it can’t afford journal publishers’ prices
28 Sep, 2020 | 01:23h | UTCHarvard University says it can’t afford journal publishers’ prices – The Guardian
Related: UC Terminates Subscriptions with World’s Largest Scientific Publisher in Push for Open Access (several resources on the subject)
Britain will ‘host world’s first Covid-19 vaccine challenge trial’
24 Sep, 2020 | 09:22h | UTC
COVID-19 clinical trials: Learning from exceptions in the research chaos
23 Sep, 2020 | 14:50h | UTCCOVID-19 clinical trials: learning from exceptions in the research chaos – Nature
Commentary on Twitter
Our analysis on #COVID clinical trials on Nature Medicine. Only big randomised trials can answer rapidly & reliably. Megatrials need support from regulators, funders, health services, docs. Pre-existing trial networks helpful. Collaboration key to success. https://t.co/YlalAEMR9r pic.twitter.com/wElfXfXdol
— Kari Tikkinen (@KariTikkinen) September 22, 2020
When to replicate systematic reviews of interventions: Consensus checklist
17 Sep, 2020 | 09:23h | UTCWhen to replicate systematic reviews of interventions: consensus checklist – The BMJ
Commentary on Twitter
Delighted this is out today! Thanks to @CIHR_IRSC funding and great team: When to replicate systematic reviews of interventions: consensus checklist https://t.co/1WDc9a6VBq
— Vivian A Welch (@vawelch) September 15, 2020
Estimating risk ratios and risk differences: Alternatives to odds ratios
17 Sep, 2020 | 09:25h | UTCEstimating Risk Ratios and Risk Differences: Alternatives to Odds Ratios – JAMA (free for a limited period)
Commentary on Twitter
Why Risk Ratios and Risk Differences are better than odds ratios https://t.co/zGOKAMQDHI via @JAMA_current part of @JAMANetwork
— Ed Livingston (@ehlJAMA) September 16, 2020
Open letter calls on cardiovascular societies to discourage cardiac magnetic resonance after mild COVID-19
16 Sep, 2020 | 09:09h | UTCOpen Letter Calls on CV Societies to Discourage CMR After Mild COVID-19 – TCTMD
UK tests if COVID-19 vaccines might work better inhaled
16 Sep, 2020 | 08:56h | UTCUK tests if COVID-19 vaccines might work better inhaled – Associated Press
Coronavirus: Monoclonal antibodies to begin UK trial
16 Sep, 2020 | 08:53h | UTCCoronavirus: Monoclonal antibodies to begin UK trial – BBC
See also: Covid-19: RECOVERY trial will evaluate “antiviral antibody cocktail” – The BMJ
NIH launches two trials to test blood thinners in COVID-19 patients
15 Sep, 2020 | 08:56h | UTCNIH launches two trials to test blood thinners in COVID-19 patients – Reuters