Endocrinology (all articles)
Study: polycystic ovary syndrome and risk of diabetes
9 Sep, 2017 | 21:55h | UTCDevelopment and risk factors of type 2 diabetes in a nationwide population of women with polycystic ovary syndrome – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Type 2 diabetes risk four times higher in women with PCOS – Medical News Today (free) AND Researchers reveal link between PCOS, type 2 diabetes – The Endocrine Society, via EurekAlert (free)
Systematic Review: Efficacy of dietary and physical activity intervention in non-alcoholic fatty liver disease
9 Sep, 2017 | 18:44h | UTCSource: Medscape
Postpartum Depression Can Affect Dads – and their hormones may be to blame
9 Sep, 2017 | 16:50h | UTCPostpartum Depression Can Affect Dads – and their hormones may be to blame – The Conversation (free)
Original article: High paternal testosterone may protect against postpartum depressive symptoms in fathers, but confer risk to mothers and children – Hormones and Behavior (link to abstract – $ for full-text)
Meta-analysis: Use of supplemental long-chain omega-3 fatty acids and risk for cardiac death
9 Sep, 2017 | 16:03h | UTCCommentary: Omega-3 Intake Reduces Cardiac Death Risk – Pharmacy Practice Reviews (free registration required)
Related guideline and commentaries: Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease: A Science Advisory from the American Heart Association (free PDF) AND Commentary: Omega-3 Fish Oil Supplements – Taking Stock and Awaiting Vital New Studies (free) AND AHA News: Fish oil supplements provide some benefit after heart attack, heart failure (free) AND News Release: Fish oil supplements may help prevent death after a heart attack but lack evidence of cardiovascular benefit for the general population – American Heart Association Science Advisory (free) AND Top Ten Things to Know (free PDF)
Study: Association of pre-pregnancy body mass index with offspring metabolic profile
8 Sep, 2017 | 02:33h | UTCCommentary: Mothers, Fathers and Obesity in Offspring (10 articles per month are free)
Study: Efficacy and Safety of Degludec versus Glargine in Type 2 Diabetes
7 Sep, 2017 | 23:44h | UTCEfficacy and Safety of Degludec versus Glargine in Type 2 Diabetes – New England Journal of Medicine (free)
Commentary: Degludec versus Glargine in Type 2 Diabetes – NEJM Resident 360 (free)
New tool identifies diabetes patients at risk for hypoglycemia-related Emergency emergencies
7 Sep, 2017 | 21:37h | UTCDevelopment and Validation of a Tool to Identify Patients With Type 2 Diabetes at High Risk of Hypoglycemia-Related Emergency Department or Hospital Use – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: New tool identifies diabetes patients at risk for low blood sugar emergencies – Kaiser Permanente, via EurekAlert (free) AND Simple Tool Identifies Hypoglycemia Risk in Type 2 Diabetes – Medscape (free registration required) AND Identifying T2D Patients at Risk for Hypoglycemia Hospitalization – MedPage Today (free registration required)
New Economic Analyses Fail To Make Case For PCSK9 Inhibitors
7 Sep, 2017 | 20:52h | UTCNew Economic Analyses Fail To Make Case For PCSK9 Inhibitors – Cardiobrief (free)
Guideline: Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk
7 Sep, 2017 | 20:14h | UTCCommentary: Updated Decision Pathway For Non-Statin Therapies Published – American College of Cardiology, Latest in Cardiology (free)
Report: Endocrine-Disrupting Chemicals
4 Sep, 2017 | 15:44h | UTCCan low doses of chemicals affect your health? A new report weighs the evidence – The Conversation (free)
Original report: Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals – The National Academies Press (free)
Related Scientific Statement: EDC-2: The Endocrine Society’s Second Scientific Statement on Endocrine-Disrupting Chemicals (free) AND Executive Summary (free)
Source: Global Health NOW Newsletter
Guideline: Obesity in Adolescents
4 Sep, 2017 | 14:20h | UTCCommittee Opinion: Obesity in Adolescents – American College of Obstetricians and Gynecologists (free)
Commentary: ACOG Offers Tips for Managing Obesity in Adolescents – Physician’s First Watch (free)
Study: Accelerometer-assessed sedentary work, leisure time and cardio-metabolic biomarkers during one year
3 Sep, 2017 | 21:16h | UTCCommentaries: Sitting for 20 minutes less a day won’t make you ‘more muscly’ – NHS Choices (free) AND Just 21 minutes less sitting improves health – Medical News Today (free)
New Nutrition Study Changes Nothing (commentaries on the PURE study)
3 Sep, 2017 | 21:15h | UTCNew Nutrition Study Changes Nothing – The Atlantic (free) (RT @drjohnm see Tweet)
See original article and commentaries in our August 30 issue (see #1 and #2)
“Why the science of healthy eating appears confusing – but isn’t”
In health push, Singapore gets soda makers to cut sugar content
1 Sep, 2017 | 19:02h | UTCIn health push, Singapore gets soda makers to cut sugar content – Reuters (free)
See related articles on fiscal policies to reduce sugar consumption in our June 8th issue (see #4) and in our April 20th issue (see #1)
Study: Software-guided versus nurse-directed blood glucose control in critically ill patients
1 Sep, 2017 | 18:47h | UTCSource: Hospital Medicine Virtual Journal Club
Study: Active Surveillance for Low-Risk Papillary Thyroid Cancer May be Safe
31 Aug, 2017 | 22:34h | UTCNatural History and Tumor Volume Kinetics of Papillary Thyroid Cancers During Active Surveillance – JAMA Otolaryngology Head & Neck Surgery (free for a week)
Author interview audio: Natural History and Tumor Volume Kinetics of Papillary Thyroid Cancers (free)
Commentaries: Findings Support Use of Active Surveillance for Low-Risk Papillary Thyroid Cancer – The JAMA Network (free) AND Many People Can Delay Treatment For Thyroid Cancer, Study Finds – NPR (free)
Guidelines for the diagnosis and treatment of postmenopausal osteoporosis
31 Aug, 2017 | 19:27h | UTC
Guideline: Vitamin D Supplementation
31 Aug, 2017 | 19:42h | UTCPublic Health Guideline: Vitamin D: supplement use in specific population groups – National Institute for Health and Care Excellence (NICE) (free)
“Only test vitamin D status if someone has symptoms of deficiency or is at very high risk”
Study: Impact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations
31 Aug, 2017 | 16:31h | UTCImpact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations – The Annals of Thoracic Surgery (link to abstract – $ for full-text)
Commentaries: Obese cardiac patients a drain on ICU resources – Cardiovascular Business (free) AND Obese Cardiac Surgery Patients a Burden on ICU Resources – TCTMD (free) AND Post–Cardiac Surgery ICU Usage Rises With Increasing Obesity – Medscape (free registration required)
Study: Cognitive Function in a Randomized Trial of Evolocumab
31 Aug, 2017 | 15:35h | UTCCognitive Function in a Randomized Trial of Evolocumab – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Cholesterol-Lowering Drug Evolocumab Doesn’t Seem to Impair Cognition – Physician’s First Watch (free)
“The authors caution that most people take cholesterol-lowering medications for decades, and this was a much shorter follow-up period” (from Physician’s First Watch).
#ESCCongress – Cohort Study: Fruit, vegetable, and legume intake, and cardiovascular disease and deaths
30 Aug, 2017 | 18:32h | UTC#ESCCongress – Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Reassessing the benefits of plant-based eating (PURE) – ESC Press Release (free) Fruit, Vegetable, Legume Intake and CVD Events – American College of Cardiology, Latest in Cardiology (free) AND Life-saving fruit and vegetable diet need only be three portions – study – The Guardian (free) AND Less Is More? Health Benefits of Fruits, Vegetables, and Legumes Seen at Lower Intake Levels – TCTMD (free)
#ESCCongress – Cohort Study: Associations of fats and carbohydrate intake with cardiovascular disease and mortality
30 Aug, 2017 | 18:33h | UTC#ESCCongress – Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Revisiting dietary fat guidelines? (PURE) – ESC Press Release (free) AND PURE Investigators: Rethink Diet Guidance to Plug More Fats, Fewer Carbs – TCTMD (free) AND International study shows moderate consumption of fats and carbohydrates best for health – McMaster University, via EurekAlert (free) AND PURE: Findings Could Have Implications For Global Dietary Guidelines – ACC News Story (free) AND Huge Diet Study Questions Conventional Wisdom About Carbs And Fats – Cardiobrief (free)
#ESCCongress – Study: Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
30 Aug, 2017 | 18:29h | UTCCommentaries: Anacetrapib REVEALs ‘Modest’ Effect on Cardiovascular Outcomes – Medscape (free registration required) AND Anacetrapib Finds (Modest) Success Where All Other CETP Inhibitors Failed – TCTMD (free) AND REVEAL Revealed: A Slightly Positive CETP Inhibitor Trial – Cardiobrief (free)
Interesting new drug, but with modest benefits. During the median follow-up period of 4.1 years, the primary outcome occurred in fewer patients in the anacetrapib group than in the placebo group (10.8% vs. 11.8% / absolute risk difference = 1%, meaning 100 patients would have to be treated for 4.1 years to benefit 1 patient)
Are expanding disease definitions unnecessarily labelling women with polycystic ovary syndrome?
30 Aug, 2017 | 18:03h | UTCCommentaries: Why the definition of polycystic ovary syndrome harms women – Medical News Today (free) AND Five commonly over-diagnosed conditions and what we can do about them – The Conversation (free)
Guidelines: Thyroid Nodule Molecular Fine-Needle Aspiration Cytology Diagnostics
30 Aug, 2017 | 17:59h | UTC