Endocrinology (all articles)
Viewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension
22 Mar, 2018 | 23:43h | UTCViewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension: Comparing the ADA and the ACC/AHA Recommendations – JAMA (free for a limited period)
Consensus Recommendations on Sulfonylurea and Sulfonylurea Combinations in the Management of Type 2 Diabetes Mellitus
22 Mar, 2018 | 23:35h | UTC
Did a pricey cholesterol-lowering drug really reduce deaths, as headlines claim?
16 Mar, 2018 | 03:33h | UTCSee original article and commentaries in our March 12th issue (see #2)
The ODYSSEY Trial Ends Well— But Will It Be Enough?
16 Mar, 2018 | 03:32h | UTC#ACC18 – The ODYSSEY Trial Ends Well— But Will It Be Enough? – Cardiobrief (free) AND Ten Quick Thoughts on ODYSSEY – John Mandrola, via Medscape (free registration required)
“An absolute risk reduction of 1.6% in the primary endpoint translates to a number needed to treat of 64. Using the current price of $14,500 per year, Kaul calculated that preventing one event over the trial period of almost 3 years would cost about $2.6 million” (via John Mandrola). This study was presented at #ACC18 and has not been published yet. Among the many commentaries, these two were selected for a balanced point of view.
Research: Vitamin D and risk of total and site specific cancers
16 Mar, 2018 | 03:26h | UTC“Wake me up when there is a positive randomized trial of vitamin D pills for anything” (from Richard Lehman’s review).
Guideline: Evaluation and Treatment of Hirsutism in Premenopausal Women
16 Mar, 2018 | 02:28h | UTCKey Points: Evaluation and Treatment of Hirsutism in Premenopausal Women – JAMA Clinical Guidelines Synopsis (free for a limited period)
Research: Calcium and vitamin D supplementation and increased risk of serrated polyps
16 Mar, 2018 | 02:10h | UTCCalcium and vitamin D supplementation and increased risk of serrated polyps: results from a randomised clinical trial – Gut (link to abstract – $ for full-text)
Commentaries: Calcium and vitamin D supplements may raise risk of polyps – MedicalNewsToday (free) AND Calcium Supplements Up Risk for Precancerous Serrated Polyps – Medscape (free registration required)
See related meta-analysis of RCT showing calcium and vitamin D don’t prevent bone fractures
Statement: ADA Deeply Concerned About New Guidance from ACP Regarding Blood Glucose Targets
16 Mar, 2018 | 02:10h | UTCSee original guideline and commentary: ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
Research: Low-Calorie Vegetarian vs Mediterranean Diets
16 Mar, 2018 | 01:43h | UTCLow-Calorie Vegetarian Versus Mediterranean Diets for Reducing Body Weight and Improving Cardiovascular Risk Profile: CARDIVEG Study (Cardiovascular Prevention With Vegetarian Diet) – Circulation (free PDF for a limited period)
Commentaries: Low-Calorie Vegetarian vs. Mediterranean Diets – American College of Cardiology, Latest in Cardiology (free) AND Vegetarian and Mediterranean diet may be equally effective in preventing heart disease – American Heart Association, via ScienceDaily (free)
Research: Vegan Diet Improves Diabetes Markers
16 Mar, 2018 | 01:10h | UTCCommentaries: Vegan Diet Rapidly Improves Type 2 Diabetes Markers in Adults – Medscape (free registration required) AND Going vegan could prevent type 2 diabetes – MedicalNewsToday (free) AND New study shows vegan diet improves diabetes markers in overweight adults – EurekAlert (free)
Meta-analysis: carbohydrate restriction on glycemic control in adults with diabetes
16 Mar, 2018 | 00:54h | UTCEffect of dietary carbohydrate restriction on glycemic control in adults with diabetes: a systematic review and meta-analysis – Diabetes Research and Clinical Practice (link to abstract – $ for full-text)
“Carbohydrate-restricted diets, associated with reductions in HbA1c of around 0.4% in short term” (via @kamleshkhunti see Tweet)
ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
8 Mar, 2018 | 22:32h | UTCCommentary: Major Medical Associations Feud Over Diabetes Guidelines – NPR (free)
“Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with type 2 diabetes”
Novel subgroups of adult-onset diabetes and their association with outcomes
8 Mar, 2018 | 22:29h | UTCNovel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: 5 Classifications of Diabetes Proposed – Physician’s First Watch (free) AND Should diabetes be divided into 5 categories to improve treatment? – Cardiovascular Business (free) AND Diabetes Consists of Five Types, Not Two, Say Researchers – Medscape (free registration required)
Research: Metformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age
8 Mar, 2018 | 22:13h | UTCMetformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age; follow-up of two RCTs – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Diabetes drug use during pregnancy linked to child’s weight – The Endocrine Society, via ScienceDaily (free) AND Diabetes drug use during pregnancy affects child’s weight – OnMedica (free) AND Metformin in Pregnancy May Increase Childhood Obesity Risk – Medscape (free registration required)
Scientific Statement: Obesity Management
8 Mar, 2018 | 21:40h | UTCThe Science of Obesity Management: An Endocrine Society Scientific Statement – Endocrine Reviews (free)
Commentary: Research Finds Little Difference Among Diet Plans’ Long-Term Effectiveness – Endocrine Society, via NewWise (free)
Guidelines for the Use of Antiplatelet Therapy
2 Mar, 2018 | 01:57h | UTCRelated guidelines: 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)
Guideline: pharmacological management of patients with type 2 diabetes and cardiovascular diseases
2 Mar, 2018 | 01:55h | UTCRelated guideline: Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes, 2018 – American Diabetes Association (free)
Review: Medical Management of the Postoperative Bariatric Surgery Patient
2 Mar, 2018 | 01:29h | UTCMedical Management of the Postoperative Bariatric Surgery Patient – Endotext (free)
Related Guideline: Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management (free)
Research: Measures of General and Central Adiposity and the Risk of Myocardial Infarction
2 Mar, 2018 | 01:19h | UTCSex Differences in the Association Between Measures of General and Central Adiposity and the Risk of Myocardial Infarction: Results From the UK Biobank – Journal of the American Heart Association (free for a limited period)
Commentaries: Wait and hip measurement better indicator of heart attack risk than obesity – OnMedica (free) AND Larger waist, hips may raise women’s heart attack risk – MedicalNewsToday (free)
Research: Bariatric Surgery Associated With Reduced Need For Diabetes Medications 6 Years Later
2 Mar, 2018 | 01:10h | UTCAssociation Between Bariatric Surgery and Rates of Continuation, Discontinuation, or Initiation of Antidiabetes Treatment 6 Years Later – JAMA Surgery (link to abstract – $ for full-text)
Commentaries: Bariatric Surgery Associated With Reduced Need For Diabetes Medications at Six Years – MedicalResearch (free) AND Roughly Half of Obese Patients Who Have Bariatric Surgery Are Off Type 2 Diabetes Meds at 6 Years – TCTMD (free)
See related studies on the long-term effects of Bariatric Surgery in our January 17th issue (see #1, #2 and #3)
Diabetes drug aids fertility in women with polycystic ovaries
1 Mar, 2018 | 22:03h | UTCDiabetes drug aids fertility in women with polycystic ovaries – NIHR Signal (free)
Original article: Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility – Cochrane Library (free)
Plastic Additive BPA Not Much Of A Threat, Government Study Finds
27 Feb, 2018 | 17:15h | UTCPlastic Additive BPA Not Much Of A Threat, Government Study Finds – NPR (free)
See original FDA statement on National Toxicology Program draft report on Bisphenol A (free) AND Endocrine Society Experts Express Concern with FDA Statement on BPA Safety – Endocrine Society, via NewsWise (free)
Review: Pheochromocytoma and Paraganglioma
27 Feb, 2018 | 16:38h | UTCPheochromocytoma and Paraganglioma – Endotext (free)
Review: Skin Manifestations of Diabetes Mellitus
27 Feb, 2018 | 16:37h | UTCSkin Manifestations of Diabetes Mellitus – Endotext (free)
Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How?
27 Feb, 2018 | 16:31h | UTCPost-Traumatic Hypopituitarism—Who Should Be Screened, When, and How? – Frontiers in Endocrinology (free)