Endocrinology (all articles)
Viewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension
30 Mar, 2018 | 03:48h | UTCViewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension: Comparing the ADA and the ACC/AHA Recommendations – JAMA (free for a limited period)
Summary: U.S. Preventative Services Task Force – Screening for Thyroid Cancer
30 Mar, 2018 | 03:29h | UTCSummary: U.S. Preventative Services Task Force – Screening for Thyroid Cancer: Recommendation Statement – American Family Physician (free)
The Highs and Lows of Testosterone
30 Mar, 2018 | 03:11h | UTCThe Highs and Lows of Testosterone – The New York Times (10 articles per month are free)
Original guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline (free)
Influence of sleep restriction on weight loss outcomes associated with caloric restriction
30 Mar, 2018 | 03:00h | UTCInfluence of sleep restriction on weight loss outcomes associated with caloric restriction – Sleep (link to abstract – $ for full-text)
Commentary: Losing sleep might make it harder to lose body fat – Reuters (free)
Research: Comparison of Surgical and Medical Therapy for Type 2 Diabetes in Severely Obese Adolescents
30 Mar, 2018 | 02:38h | UTCComparison of Surgical and Medical Therapy for Type 2 Diabetes in Severely Obese Adolescents – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Bariatric surgery linked to positive outcomes in very obese adolescents with type 2 diabetes – News Medical (free) AND Surgery Tied to Better Outcomes in Kids with T2D – MedPage Today (free registration required)
For hypertension and diabetes, lower treatment targets not necessarily better
23 Mar, 2018 | 02:47h | UTCRelated: AAFP Decides to Not Endorse AHA/ACC Hypertension Guideline (free) AND ACC/AHA Hypertension Guideline: What Is New? What Do We Do? – American Family Physician (free) AND Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)
Research: associations of different adiposity measures with the incidence of cardiovascular disease
23 Mar, 2018 | 01:48h | UTCCommentaries: New study casts further doubt on the idea that you can be ‘fat and fit’ – NHS Choices (free) AND A ‘Sweet Spot’ for Heart Health – The New York Times (10 articles per month are free)
Research: Cardiovascular and renal burdens of prediabetes
22 Mar, 2018 | 23:58h | UTCCardiovascular and renal burdens of prediabetes in the USA: analysis of data from serial cross-sectional surveys, 1988–2014 – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Slightly elevated blood sugar tied to heart and kidney problems – Reuters (free) AND Study finds prediabetes patients at heightened risk for cardiovascular and chronic kidney diseases – MedicalXpress (free)
Guideline: Testosterone Therapy in Men With Hypogonadism
23 Mar, 2018 | 01:47h | UTCClinical Guideline Synopsis: Evaluation and Treatment of Male Hypogonadism – JAMA (free)
Original Guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
Commentary: New Testosterone Treatment Guidelines ‘Useful but Not Gospel’ – Medscape (free registration required)
Diabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes
22 Mar, 2018 | 23:56h | UTCDiabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes – Diabetic Medicine (free PDF for a limited period)
Commentary: New Diabetes UK Nutrition Guidance Supports Individual Approach – Medscape (free registration required)
Viewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension
22 Mar, 2018 | 23:43h | UTCViewpoint: Individualizing Blood Pressure Targets for People With Diabetes and Hypertension: Comparing the ADA and the ACC/AHA Recommendations – JAMA (free for a limited period)
Consensus Recommendations on Sulfonylurea and Sulfonylurea Combinations in the Management of Type 2 Diabetes Mellitus
22 Mar, 2018 | 23:35h | UTC
Did a pricey cholesterol-lowering drug really reduce deaths, as headlines claim?
16 Mar, 2018 | 03:33h | UTCSee original article and commentaries in our March 12th issue (see #2)
The ODYSSEY Trial Ends Well— But Will It Be Enough?
16 Mar, 2018 | 03:32h | UTC#ACC18 – The ODYSSEY Trial Ends Well— But Will It Be Enough? – Cardiobrief (free) AND Ten Quick Thoughts on ODYSSEY – John Mandrola, via Medscape (free registration required)
“An absolute risk reduction of 1.6% in the primary endpoint translates to a number needed to treat of 64. Using the current price of $14,500 per year, Kaul calculated that preventing one event over the trial period of almost 3 years would cost about $2.6 million” (via John Mandrola). This study was presented at #ACC18 and has not been published yet. Among the many commentaries, these two were selected for a balanced point of view.
Research: Vitamin D and risk of total and site specific cancers
16 Mar, 2018 | 03:26h | UTC“Wake me up when there is a positive randomized trial of vitamin D pills for anything” (from Richard Lehman’s review).
Guideline: Evaluation and Treatment of Hirsutism in Premenopausal Women
16 Mar, 2018 | 02:28h | UTCKey Points: Evaluation and Treatment of Hirsutism in Premenopausal Women – JAMA Clinical Guidelines Synopsis (free for a limited period)
Research: Calcium and vitamin D supplementation and increased risk of serrated polyps
16 Mar, 2018 | 02:10h | UTCCalcium and vitamin D supplementation and increased risk of serrated polyps: results from a randomised clinical trial – Gut (link to abstract – $ for full-text)
Commentaries: Calcium and vitamin D supplements may raise risk of polyps – MedicalNewsToday (free) AND Calcium Supplements Up Risk for Precancerous Serrated Polyps – Medscape (free registration required)
See related meta-analysis of RCT showing calcium and vitamin D don’t prevent bone fractures
Statement: ADA Deeply Concerned About New Guidance from ACP Regarding Blood Glucose Targets
16 Mar, 2018 | 02:10h | UTCSee original guideline and commentary: ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
Research: Low-Calorie Vegetarian vs Mediterranean Diets
16 Mar, 2018 | 01:43h | UTCLow-Calorie Vegetarian Versus Mediterranean Diets for Reducing Body Weight and Improving Cardiovascular Risk Profile: CARDIVEG Study (Cardiovascular Prevention With Vegetarian Diet) – Circulation (free PDF for a limited period)
Commentaries: Low-Calorie Vegetarian vs. Mediterranean Diets – American College of Cardiology, Latest in Cardiology (free) AND Vegetarian and Mediterranean diet may be equally effective in preventing heart disease – American Heart Association, via ScienceDaily (free)
Research: Vegan Diet Improves Diabetes Markers
16 Mar, 2018 | 01:10h | UTCCommentaries: Vegan Diet Rapidly Improves Type 2 Diabetes Markers in Adults – Medscape (free registration required) AND Going vegan could prevent type 2 diabetes – MedicalNewsToday (free) AND New study shows vegan diet improves diabetes markers in overweight adults – EurekAlert (free)
Meta-analysis: carbohydrate restriction on glycemic control in adults with diabetes
16 Mar, 2018 | 00:54h | UTCEffect of dietary carbohydrate restriction on glycemic control in adults with diabetes: a systematic review and meta-analysis – Diabetes Research and Clinical Practice (link to abstract – $ for full-text)
“Carbohydrate-restricted diets, associated with reductions in HbA1c of around 0.4% in short term” (via @kamleshkhunti see Tweet)
ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
8 Mar, 2018 | 22:32h | UTCCommentary: Major Medical Associations Feud Over Diabetes Guidelines – NPR (free)
“Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with type 2 diabetes”
Novel subgroups of adult-onset diabetes and their association with outcomes
8 Mar, 2018 | 22:29h | UTCNovel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: 5 Classifications of Diabetes Proposed – Physician’s First Watch (free) AND Should diabetes be divided into 5 categories to improve treatment? – Cardiovascular Business (free) AND Diabetes Consists of Five Types, Not Two, Say Researchers – Medscape (free registration required)
Research: Metformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age
8 Mar, 2018 | 22:13h | UTCMetformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age; follow-up of two RCTs – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Diabetes drug use during pregnancy linked to child’s weight – The Endocrine Society, via ScienceDaily (free) AND Diabetes drug use during pregnancy affects child’s weight – OnMedica (free) AND Metformin in Pregnancy May Increase Childhood Obesity Risk – Medscape (free registration required)
Scientific Statement: Obesity Management
8 Mar, 2018 | 21:40h | UTCThe Science of Obesity Management: An Endocrine Society Scientific Statement – Endocrine Reviews (free)
Commentary: Research Finds Little Difference Among Diet Plans’ Long-Term Effectiveness – Endocrine Society, via NewWise (free)