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Endocrinology (all articles)

ADA Guideline: Type 1 Diabetes in Children and Adolescents

28 Sep, 2018 | 00:54h | UTC

Type 1 Diabetes in Children and Adolescents: A Position Statement by the American Diabetes Association – Diabetes Care (free)

 


Review: Diagnostic Testing for Elevated Cortisol in the Setting of an Adrenal Mass

27 Sep, 2018 | 22:35h | UTC

Diagnostic Testing for Elevated Cortisol in the Setting of an Adrenal Mass – JAMA (free for a limited period)

 


Opinion: Everything You Know About Obesity Is Wrong

21 Sep, 2018 | 01:59h | UTC

Everything You Know About Obesity Is Wrong – HuffPost (free) (via @cardiobrief)

“For decades, the medical community has ignored mountains of evidence to wage a cruel and futile war on fat people, poisoning public perception and ruining millions of lives.”

 


Cohort Study: Association Between Maternal Gluten Intake and Type 1 Diabetes in Offspring

21 Sep, 2018 | 01:56h | UTC

Association between maternal gluten intake and type 1 diabetes in offspring: national prospective cohort study in Denmark – The BMJ (free)

Editorial: Dietary gluten and type 1 diabetes (free for a limited period)

Commentaries: Expert reaction to research on high gluten intake during pregnancy and type 1 diabetes in children – Science Media Centre (free) AND Higher Gluten Intake in Pregnancy Tied to Increased Diabetes Risk in Offspring – Physician’s First Watch (free) AND High gluten intake during pregnancy associated with diabetes – OnMedica (free)’

“As such these results, whilst well executed and very interesting, would need to be confirmed within independent similarly sized or bigger studies as stated by the authors themselves.” (from Science Media Centre)

 


USPSTF Statement: Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults

20 Sep, 2018 | 19:46h | UTC

Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in Adults: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Author Interview: USPSTF Recommendation: Behavioral Interventions to Prevent Adult Obesity-Related Outcomes (free)

Editorials: Weight Management in Adults With Obesity: What Is a Primary Care Clinician to Do? (free for a limited period) AND Treating Obesity—Moving From Recommendation to Implementation (free for a limited period)

Commentaries: Intensive lifestyle changes best for people with BMI above 30, task force says – UPI (free) AND Doctors Should Send Obese Patients To Diet Counseling, Panel Says. But Many Don’t – NPR (free)

 


Study: Daily Fasting Improves Health and Survival in Male Mice

20 Sep, 2018 | 19:44h | UTC

Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories – Cell Metabolism (link to abstract and infographic – $ for full-text)

Commentaries: Fasting increases health and lifespan in male mice – NIH Research Matters (free) AND Study: Mice healthier, live longer with increased daily fasting times – UPI (free) AND Study: Daily Fasting Improves Health and Longevity in Male Mice – Sci News (free)

 


Cohort Study: Higher Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes

20 Sep, 2018 | 19:43h | UTC

Higher Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes among Middle-Aged Men and Women: The Danish Diet, Cancer, and Health Cohort – The Journal of Nutrition (link to abstract – $ for full-text)

Commentary: What you need to know about claims that whole grains can prevent diabetes – Health News Review (free)

 


Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

20 Sep, 2018 | 19:25h | UTC

Effect of Aspirin on All-Cause Mortality in the Healthy Elderly – New England Journal of Medicine (free) (via @EricTopol)

Related Studies: Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly – New England Journal of Medicine (free) AND Effect of Aspirin on Disability-free Survival in the Healthy Elderly – New England Journal of Medicine (free)

Commentaries: Daily low-dose aspirin found to have no effect on healthy life span in older people- NIH News Releases (free) AND Low-Dose Aspirin Late in Life? Healthy People May Not Need It – The New York Times (10 articles per month are free)

 


Guideline for the Management of Graves’ Hyperthyroidism

14 Sep, 2018 | 01:35h | UTC

2018 European Thyroid Association Guideline for the Management of Graves’ Hyperthyroidism – European Thyroid Journal (free) (via @CristobMorales and @Abraham_RMI)

 


Study: Statins for Primary Prevention in Old and Very Old Adults

14 Sep, 2018 | 01:26h | UTC

Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study – The BMJ (free)

Editorial: Primary prevention with statins for older adults (free)

Commentaries: Expert reaction to study on use of statins in older people – Science Media Centre (free) AND Widespread use of statins in healthy older people to prevent heart disease not recommended in new study – BMJ, via ScienceDaily (free)

“New research does not support widespread use of statins in healthy older people to prevent heart disease and stroke. Results found that any protective effect was limited to those with type 2 diabetes aged between 75 and 84” (via @bmj_latest see Tweet)

 


WHO Guideline: Medicines for the Treatment of Diabetes in Low-Resource Settings

6 Sep, 2018 | 02:42h | UTC

Medicines for Treatment Intensification in Type 2 Diabetes and Type of Insulin in Type 1 and Type 2 Diabetes in Low-Resource Settings: Synopsis of the World Health Organization Guidelines on Second- and Third-Line Medicines and Type of Insulin for the Control of Blood Glucose Levels in Nonpregnant Adults With Diabetes Mellitus – Annals of Internal Medicine (free)

Original Guideline: Guidelines on second-and third-line medicines and type of insulin for the control of blood glucose levels in non-pregnant adults with diabetes mellitus – World Health Organization (free PDF)

 


Review: Risk Stratification on Pheochromocytoma and Paraganglioma from Laboratory and Clinical Medicine

2 Sep, 2018 | 02:06h | UTC

Risk Stratification on Pheochromocytoma and Paraganglioma from Laboratory and Clinical Medicine – Journal of Clinical Medicine (free)

 


Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

31 Aug, 2018 | 03:07h | UTC

Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus – New England Journal of Medicine (free for a limited period)

Commentaries: Bleeds and benefit with aspirin balanced in patients with diabetes and no effect on cancer – ESC Press Releases (free) AND  ASCEND: Aspirin Doesn’t Look Good for Primary CV Prevention in Diabetic Patients – TCTMD (free)

 


Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

31 Aug, 2018 | 03:06h | UTC

Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Aspirin Fails to Prevent CV Events in People at ‘Moderate’ Risk of Disease: ARRIVE – TCTMD (free) AND ARRIVE: New Findings Contribute to Growing Body of Evidence Surrounding Aspirin Use – American College of Cardiology (free) AND Daily Aspirin Fails to Lower CV Risk in Long-term, Primary Prevention ARRIVE Trial – Medscape (free registration required) AND Jury still out on aspirin a day to prevent heart attack and stroke – ESC Press Releases (free)

 


Randomized Trial: Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus

31 Aug, 2018 | 02:58h | UTC

Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus – New England Journal of Medicine (free for a limited period)

Commentaries: Fish oils do not prevent heart attack or strokes in people with diabetes – ESC News Releases (free) AND Omega-3 Fatty Acids Fail to Reduce CVD Events in Diabetic Patients: ASCEND – TCTMD (free)

Related Cochrane Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (link to abstract and commentaries)

Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free study and commentary)

 


Study: Vitamin D Not Linked to Fracture Risk

31 Aug, 2018 | 02:43h | UTC

Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study – The BMJ (free)

Commentaries: Vitamin D: a pseudo-vitamin for a pseudo-disease – The Conversation (free) AND Fracture risk not linked to low vitamin D or calcium levels – OnMedica (free)

Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline)

 


Randomized Trial: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients

31 Aug, 2018 | 01:58h | UTC

Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients – New England Journal of Medicine (free for a limited period)

Editorial: Lorcaserin — Elixir or Liability? (free for a limited period)

Commentaries: CAMELLIA-TIMI 61: Weight Loss Drug Lorcaserin Did Not Increase CV Events – American College of Cardiology (free) AND Weight-Loss Drug Lorcaserin Clears Cardiovascular Safety Hurdle: CAMELLIA-TIMI 61 – TCTMD (free) AND Weight loss drug lorcaserin found safe in large study – Reuters (free)

 


Guiding Principles for the Care of People with or at Risk for Diabetes

31 Aug, 2018 | 02:00h | UTC

Guiding Principles for the Care of People With or at Risk for Diabetes – National Institute of Diabetes and Digestive and Kidney Diseases (free PDF)

Commentaries: NIDDK Updates ‘Guiding Principles’ for Diabetes, Prediabetes – Medscape (free registration required) AND NDEP revises principles for managing diabetes, prediabetes – Cardiovascular Business (free)

Related Book: Diabetes in America, 3rd Edition – National Institutes of Health (free reference book, just released)

 


Cohort Study: Long-Term Association of LDL Cholesterol With Cardiovascular Mortality in Low-Risk Individuals

23 Aug, 2018 | 23:22h | UTC

Long-Term Association of Low-Density Lipoprotein Cholesterol With Cardiovascular Mortality in Individuals at Low 10-Year Risk of Atherosclerotic Cardiovascular Disease – Circulation (free)

Commentaries: ‘Bad’ cholesterol can be deadly in otherwise healthy people – AHA News (free) AND LDL >160 Tied to Increased Mortality in Low-Risk Patients – Physician’s First Watch (free) AND Study: Elevated LDL, non-HDL increase CVD mortality risk in young, healthy individuals – Cardiovascular Business (free) AND Moderate ‘bad cholesterol’ levels tied to early death for healthy people – Reuters (free)

 


Perspective: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It

23 Aug, 2018 | 22:32h | UTC

Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It – The New York Times (10 articles per month are free) (via @CarlosdelRio7 see Tweet)

Related commentaries: Vitamin D Screening and Supplementation in Primary Care: Time to Curb Our Enthusiasm – American Family Physician (free) AND Your vitamin D tests and supplements are probably a waste of money – VOX (free) AND Why Are So Many People Popping Vitamin D? – The New York Times (10 articles per month are free)

Related Guideline: Vitamin D: supplement use in specific population groups – National Institute for Health and Care Excellence (free)

“Only test vitamin D status if someone has symptoms of deficiency or is at very high risk” (from NICE Guideline)

 


Study: Association of Body Mass Index With Blood Pressure

23 Aug, 2018 | 22:26h | UTC

Association of Body Mass Index With Blood Pressure Among 1.7 Million Chinese Adults – JAMA Network Open (free)

Commentary: As body mass index increases, blood pressure may as well – Yale University (free)

 


Cohort Studies: Smoking Cessation, Weight Change, Type 2 Diabetes, and Mortality

17 Aug, 2018 | 02:35h | UTC

Smoking Cessation, Weight Change, Type 2 Diabetes, and Mortality – The New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Weight gain after smoking cessation linked with increased short-term diabetes risk – Harvard T.H. Chan School of Public Health (free) AND Weight gain temporarily hikes diabetes risk when smokers quit – Reuters (free) AND Smokers Are Better Off After They Quit Even if They Gain Weight – Physician’s First Watch (free)

 


Cohort Study: Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes

17 Aug, 2018 | 02:26h | UTC

Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: In Type 2 Diabetes, Five Risk Factor Targets Keep MI, Stroke, and Death in Check – TCTMD (free) AND How People With Type 2 Diabetes Can Lower Their Risk of Health Problems – TIME (free) AND T2D, Without Other Risks, Not Tied to Excess Mortality – MedPage Today (free registration required)

 


Study: Polygenic Scores for Common Diseases Identify Individuals with Risk Equivalent to Monogenic Mutations

17 Aug, 2018 | 02:09h | UTC

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations – Nature Genetics (link to abstract – $ for full-text)

Commentaries: Researchers predict risk for common deadly diseases from millions of genetic variants – Broad Institute of MIT and Harvard, ScienceDaily (free) AND Clues to Your Health Are Hidden at 6.6 Million Spots in Your DNA – The New York Times (10 articles per month are free) AND Multi-gene test may find risk for heart disease and more – Associated Press (free) AND A Harvard Scientist Thinks He Has a Gene Test for Heart Attack Risk. He Wants to Give It Away Free – Forbes (free)

 


Book: Diabetes in America, 3rd Edition – National Institutes of Health

17 Aug, 2018 | 02:01h | UTC

Diabetes in America, 3rd Edition – National Institutes of Health (free chapters)

News Release: New NIH reference book is one-stop resource for diabetes medical information – National Institutes of Health (free)

 


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