Editor's Choice
‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses.
15 Jun, 2022 | 11:25h | UTC‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT
See also: Rename monkeypox strains to remove geographic stigma, researchers say – Science
Related:
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
AHA Scientific Statement: Toward a better understanding of sex- and gender-related differences in endovascular stroke treatment.
15 Jun, 2022 | 11:26h | UTCNews Release: More data needed on stroke treatment and outcomes by sex, gender – American Heart Association
Commentary on Twitter
Toward a Better Understanding of Sex- and Gender-Related Differences in Endovascular Stroke Treatment: A Scientific Statement From the American Heart Association/American Stroke Associationhttps://t.co/oXrdiLZfNK pic.twitter.com/Z4kMZG4Ymm
— Let's Get Proof (@letsgetproof) June 13, 2022
Review: Sepsis management for the nephrologist.
15 Jun, 2022 | 11:23h | UTCSepsis Management for the Nephrologist – Clinical Journal of the American Society of Nephrology
Pfizer’s Paxlovid study fails to answer key questions over benefit for broader populations.
15 Jun, 2022 | 11:22h | UTCPfizer’s Paxlovid study fails to answer key questions over benefit for broader populations – STAT
RCT: Effectiveness and safety of lotion, cream, gel, and ointment emollients for childhood eczema.
15 Jun, 2022 | 11:20h | UTCNews Release: The right moisturiser for children with eczema is the one that they like to use, study finds – University of Nottingham
Commentary: Lotion, Cream, Gel, and Ointment Similarly Effective for Childhood Eczema – HealthDay
Commentary on Twitter
New: @bee_study led by @riddmj found no difference in effectiveness between the four main types of emollients —lotions, creams, gels, and ointments—for childhood #eczema
The right #moisturizer is the one that children will use. https://t.co/45N5A136Kx
— The Lancet Child & Adolescent Health (@LancetChildAdol) May 24, 2022
RCT: Effect of varenicline added to counseling on smoking cessation among African American daily smokers.
15 Jun, 2022 | 11:18h | UTCEditorial: Helping African American Individuals Quit Smoking: Finally, Some Progress – JAMA
News Release: Varenicline Increases Smoking Cessation Rates for African American Smokers – University of Kansas Cancer Center
Commentary on Twitter
Study found that, among African American adults who were daily smokers, counseling + 12 weeks of varenicline treatment, vs counseling + placebo, showed a significant improvement in rates of 7-day point prevalence smoking abstinence at week 26. https://t.co/fK4NUWgkJO
— JAMA (@JAMA_current) June 14, 2022
Phase 2 RCT: Safety and immunogenicity of the AstraZeneca vaccine in children aged 6–17 years.
15 Jun, 2022 | 11:15h | UTCInvited Commentary: Increasing children’s global access to COVID-19 vaccines – The Lancet
Analysis of thromboembolic and thrombocytopenic events after the AstraZeneca, Pfizer, and Moderna COVID-19 vaccines in 3 Nordic countries.
15 Jun, 2022 | 11:17h | UTC
Guideline: Management of hyperglycemia in hospitalized adult patients in non-critical care settings.
14 Jun, 2022 | 11:22h | UTCCommentary: Endocrine Society Issues New Guidelines for Hospitalized Patients With Diabetes – Clinical Advisor
Related:
Podcast: #330 Inpatient Diabetes with Dr. Dave Lieb – The Curbsiders
Review: Managing hyperglycaemia in inpatients – Clinical Medicine Journal
State of the Art Review: Revascularization in stable coronary artery disease.
14 Jun, 2022 | 11:15h | UTCRevascularization in stable coronary artery disease – The BMJ
Guideline: Functional bowel disorders with diarrhea.
14 Jun, 2022 | 11:20h | UTC
Systematic Review: Janus kinase inhibitors for the treatment of COVID‐19.
14 Jun, 2022 | 11:14h | UTCJanus kinase inhibitors for the treatment of COVID‐19 – Cochrane Library
[Preprint] RCT: Ivermectin does not benefit patients with mild-to-moderate COVID-19 in the outpatient setting.
14 Jun, 2022 | 11:12h | UTCCommentary: Study finds no benefit to taking ivermectin for COVID-19 symptoms – Duke University
Comparative safety of BNT162b2 and mRNA-1273 vaccines in a nationwide cohort of US veterans.
14 Jun, 2022 | 11:08h | UTC
Commentary on Twitter
1/
TODAY: We compared the safety of #COVID19 mRNA vaccines in the largest healthcare system in the US.TAKE-HOME MESSAGE: Both Moderna and Pfizer vaccines are quite safe. If interested in vaccination, you can confidently use whichever one is available.https://t.co/fFIlXwH5Qv
— Miguel Hernán (@_MiguelHernan) June 13, 2022
In a study of US blood donations, the combined SARS-CoV-2 seroprevalence from infection or vaccination reached 94.7%.
14 Jun, 2022 | 11:10h | UTC
Commentary on Twitter
In this study of US blood donations, the combined seroprevalence from #SARSCoV2 infection or vaccination reached 94.7% by December 2021. https://t.co/OiHICuWDo4
— JAMA (@JAMA_current) June 13, 2022
Regional lymphadenopathy following COVID-19 vaccination in patients with or suspicious of breast cancer: a quick summary of current key facts and recommendations.
14 Jun, 2022 | 11:07h | UTCRelated:
2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
BSH guideline for the hematological management of major hemorrhage.
13 Jun, 2022 | 10:53h | UTC
Case Series | Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit.
13 Jun, 2022 | 10:46h | UTCOutbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Related: Investigating acute hepatitis of unknown origin in children (several resources on the subject)
Commentary on Twitter
Outbreak of non-A-E hepatitis in children, 🇬🇧 data. Good outcomes if ALF by dedicated liver #ICU with early referral to Tx centres, recognizing neuro-deterioration, high-volume #ECLS, close neuromonitoring/protection & support by hepatology/Tx physicians
📎https://t.co/GYAMaZbVGD pic.twitter.com/GA58vJWQIz— Intensive Care Medicine (@yourICM) June 10, 2022
WHO Interim Guidance: Clinical management and infection prevention and control for monkeypox.
13 Jun, 2022 | 10:49h | UTCRelated:
2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention
As monkeypox threat grows, scientists debate best vaccine strategy – Science
Monkeypox is a new global threat. African scientists know what the world is up against – Science
Experts highlight sexual aspect of monkeypox spread – CIDRAP
What to Know About Monkeypox – JAMA
Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization
Monkeypox outbreaks: 4 key questions researchers have – Nature
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
M-A: Respiratory viral co-infections in patients with COVID-19 and associated outcomes.
13 Jun, 2022 | 10:41h | UTC
NIH Updated Guideline: Oxygenation and ventilation for adults with Covid-19.
13 Jun, 2022 | 10:44h | UTCOxygenation and Ventilation for Adults – National Institutes of Health
RCT: Emergency vs. delayed coronary angiogram in survivors of out-of-hospital cardiac arrest.
13 Jun, 2022 | 10:42h | UTCEmergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial – JAMA Cardiology (free for a limited period)
Commentary on Twitter
In this RCT, performing an emergency coronary angiogram (CAG) after an out-of-hospital cardiac arrest without ST-segment elevation showed no difference in the 180-day survival rate compared to a delayed CAG. https://t.co/gYwPdNV32v
— JAMA Cardiology (@JAMACardio) June 8, 2022
RCT: Intramuscular tixagevimab–cilgavimab may benefit non-hospitalized unvaccinated adults with Covid-19.
13 Jun, 2022 | 10:39h | UTCCommentaries:
Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID – News Medical
Commentary on Twitter
NEW—A single intramuscular tixagevimab–cilgavimab dose provided protection against progression to severe COVID-19 or death vs placebo in unvaccinated individuals
TACKLE trial from Prof Hugh Montgomery & colleagues https://t.co/M9LENFsA2C pic.twitter.com/Aon4wJsBOi
— The Lancet Respiratory Medicine (@LancetRespirMed) June 8, 2022
One in 500 men carry extra sex chromosome, putting them at higher risk of several common diseases.
13 Jun, 2022 | 10:35h | UTCNews Release: One in 500 men carry extra sex chromosome, putting them at higher risk of several common diseases – University of Cambridge
Original Study: Detection and characterization of male sex chromosome abnormalities in the UK Biobank study – Genetics in Medicine
Commentary: One in 500 men carry extra sex chromosome, research suggests – The Guardian
Commentary on Twitter
Interesting work looking at the prevalence of male sex chromosomal abnormalities in UK Biobank.
"Only 49 of 213 (23%) of men whom we identified with KS and only 1 of 143 (0.7%) with 47,XYY had a diagnosis of abnormal karyotype on their medical records or self-report." https://t.co/3VKh2rqxyn
— Veera Rajagopal (@doctorveera) June 11, 2022
Long-term follow-up of RCT: Decompressive craniectomy vs. standard medical care in patients with traumatic intracranial hypertension.
10 Jun, 2022 | 12:45h | UTCEvaluation of Outcomes Among Patients With Traumatic Intracranial Hypertension Treated With Decompressive Craniectomy vs Standard Medical Care at 24 Months: A Secondary Analysis of the RESCUEicp Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Original Study: Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension – New England Journal of Medicine
Related:
The Current Status of Decompressive Craniectomy in Traumatic Brain Injury – Current Trauma Reports
Commentary on Twitter
In this study, at 24 months, patients with posttraumatic refractory intracranial hypertension managed with a decompressive craniectomy had a sustained mortality reduction and higher rates of vegetative state, severe disability, and moderate disability. https://t.co/I8GqG885jh
— JAMA Neurology (@JAMANeuro) June 9, 2022