Editor's Choice | Page 75 of 113 | Links Medicus Content Curation & Alerts in Medicine

Brief Review | Sudden onset hepatitis in children.

4 Jul, 2022 | 12:41h | UTC

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Related: WHO Updated Report: Severe acute hepatitis of unknown etiology in children. (several articles on the subject)

Commentary on Twitter

NEW! In this COMMENT by @ZaniaStamataki & @kellyda60 summarise what we know so far about sudden onset #hepatitis of unexplained origin in childrenhttps://t.co/AYTR8wrG3C

Read-only link https://t.co/dgyzRhpODT #paediatrics pic.twitter.com/1WLQfaRrdx

— Nature Reviews Gastroenterology & Hepatology (@NatRevGastroHep) July 1, 2022

Monkeypox soars in Europe, with more than 4,000 cases.

4 Jul, 2022 | 12:43h | UTC

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

Original Report: European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Monkeypox, Joint Epidemiological overview, 30 June, 2022

WHO Statement: No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

2022 Guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19.

1 Jul, 2022 | 11:50h | UTC

2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19 – The Lancet Oncology

Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy – Cochrane Library

American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer – Blood Advances

Cancer-Associated Venous Thromboembolic Disease, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Venous and Arterial Thromboembolism in Patients With Cancer: JACC: CardioOncology State-of-the-Art Review

Two new studies show no benefit of Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19.

1 Jul, 2022 | 11:49h | UTC

Study 1: Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet Haematology

Study 2: Thromboprophylactic low-molecular-weight heparin versus standard of care in unvaccinated, at-risk outpatients with COVID-19 (ETHIC): an open-label, multicentre, randomised, controlled, phase 3b trial – The Lancet Haematology

Commentaries:

Antithrombotic prophylaxis for symptomatic outpatients with COVID-19: less is consistently more – The Lancet Haematology

Antithrombotic Prophylaxis No Help in Outpatients With COVID — Two trials show no differences between patients who received enoxaparin vs standard of care – MedPage Today (free registration required)

Commentary on Twitter (thread – click for more)

Early in the pandemic we wondered whether antithrombotic therapy in outpatients with #COVID19 would prevent #thrombosis ❓

Several trials were started globally and the ACTIV-4B trial was previously reported⬇️ https://t.co/Q15WcZwDIA

Now, we publish the OVID and ETHIC trials🧵

— The Lancet Haematology (@TheLancetHaem) June 30, 2022

Systematic Review: Mobility training for increasing mobility and functioning in older people with frailty.

1 Jul, 2022 | 11:41h | UTC

Mobility training for increasing mobility and functioning in older people with frailty – Cochrane Library

Summary: Mobility training for increasing mobility and functioning in older people who are frail – Cochrane Library

RCT: A single immediate dose of intravenous tenecteplase is noninferior to alteplase for the treatment of patients with acute ischemic stroke.

1 Jul, 2022 | 11:44h | UTC

Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

News Release: UCalgary researchers with the Calgary Stroke Program make another breakthrough in the treatment of stroke

Accuracy of rapid antigen vs. RT-PCR testing for SARS-CoV-2 infection in college athletes during prevalence of the Omicron variant.

1 Jul, 2022 | 11:39h | UTC

Accuracy of Rapid Antigen vs Reverse Transcriptase–Polymerase Chain Reaction Testing for SARS-CoV-2 Infection in College Athletes During Prevalence of the Omicron Variant – JAMA Network Open

Commentary on Twitter

In this case series of college athletes returning to campus during Omicron, rapid antigen tests were 63% sensitive, >99% specific for #COVID19, similar to previous strains and less well in detecting asymptomatic #SARSCoV2. @helixcardinal @stanford_ortho https://t.co/SBPr6NQ9Na

— JAMA Network Open (@JAMANetworkOpen) June 15, 2022

Cohort Study: Effectiveness of Pfizer, Moderna, and AstraZeneca vaccines against severe covid-19 outcomes in a nationwide mass vaccination setting.

1 Jul, 2022 | 11:37h | UTC

Effectiveness of BNT162b2, mRNA-1273, and ChAdOx1-S vaccines against severe covid-19 outcomes in a nationwide mass vaccination setting: cohort study – BMJ Medicine

Commentary on Twitter

🎉 Read our latest research article comparing the effectiveness of three #COVID vaccines against severe COVID outcomes. ▶️ https://t.co/uaQNgnDrrV #BMJMedicine #MedTwitter #openaccess pic.twitter.com/4oeG5d0j80

— BMJMedicine (@BMJMedicine) June 16, 2022

Life’s Essential 8: Updating and enhancing the AHA construct of cardiovascular health.

30 Jun, 2022 | 11:31h | UTC

Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association – Circulation

News Release: American Heart Association adds sleep to cardiovascular health checklist

Commentary: Sleep duration matters for heart health, according to new recommendations – CNN

Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019.

30 Jun, 2022 | 11:28h | UTC

Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019 – The Lancet Public Health

News Release: The Lancet: Improving road safety measures could save half a million lives every year worldwide – Institute for Health Metrics and Evaluation

Commentaries on Twitter

(Thread – click for more)

NEW—#GBDstudy Improving road safety measures (helmets, seatbelts, obeying speed limits, and avoiding drunk driving) could save half a million lives every year WORLDWIDE. @TheLancet @LancetPH #RoadSafety #InvestInYouth https://t.co/E2RdjazHDF

— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) June 30, 2022

(Thread – click for more)

Our new research published in @TheLancetPH “highlights the neglect and chronic underinvestment by the global health community to prevent injury-related harms in adolescents.” @UNSW @UNSWMedicine @CforAH @MCRI_for_kids @IHME_UW @georgeinstitute https://t.co/gjbndubxGE

— Dr Amy Peden (@amyepeden) June 29, 2022

Cohort Study: Pfizer vaccine effectiveness against omicron in children 5 to 11 years of age.

30 Jun, 2022 | 11:21h | UTC

BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age – New England Journal of Medicine

Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis.

30 Jun, 2022 | 11:26h | UTC

Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis – The BMJ

RCT: Effects of early Empagliflozin initiation on diuresis and kidney function in patients with acute decompensated heart failure.

30 Jun, 2022 | 11:24h | UTC

Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF) – Circulation

Wearable activity trackers plus AI might be used to pick up presymptomatic COVID-19.

30 Jun, 2022 | 11:18h | UTC

News Release: Wearable activity trackers + AI might be used to pick up presymptomatic COVID-19 – BMJ Newsroom

Original Study: Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective cohort study (COVI-GAPP) – BMJ Open

Systematic Review: Long distance airborne transmission of SARS-CoV-2.

30 Jun, 2022 | 11:17h | UTC

Long distance airborne transmission of SARS-CoV-2: rapid systematic review – The BMJ

Editorial: Airborne SARS-CoV-2 – The BMJ

News Release: New review of evidence highlights importance of adequate ventilation to prevent spread of covid-19 in indoor settings – BMJ

Cohort Study: Association of time elapsed since ischemic stroke with risk of recurrent stroke in older patients undergoing elective nonneurologic, noncardiac surgery.

30 Jun, 2022 | 11:16h | UTC

Association of Time Elapsed Since Ischemic Stroke With Risk of Recurrent Stroke in Older Patients Undergoing Elective Nonneurologic, Noncardiac Surgery – JAMA Surgery (free for a limited period)

Invited Commentary: Perioperative Stroke Risk Model—One Size Fits All? – JAMA Surgery

RCT: A 2-week interruption in methotrexate treatment doubles the antibody response to a COVID-19 booster vaccine.

29 Jun, 2022 | 12:10h | UTC

Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial – The Lancet Respiratory Medicine

News Releases:

Interrupting the treatment of vulnerable people on immune-suppressing medicines, doubles their antibody response to COVID-19 booster vaccination – University of Nottingham

Interrupting immune-suppressing treatment can boost COVID vaccine response – Imperial College London

Commentaries:

Improving COVID-19 vaccine immunogenicity by interrupting methotrexate treatment – The Lancet Respiratory Medicine

Covid-19: Pausing immune suppressing drugs enhances antibody response to boosters, study shows – The BMJ

Commentary on Twitter

NEW Research—2-week interruption of methotrexate treatment for people w/ immune-mediated inflammatory diseases = enhanced boosting of antibody responses after #COVID19 vaccination

From Prof Abhishek Abhishek & colleagues https://t.co/y14pUEaB5X pic.twitter.com/pLvaXjJzoz

— The Lancet Respiratory Medicine (@LancetRespirMed) June 28, 2022

AAP Policy Statement: Breastfeeding and the use of human milk.

29 Jun, 2022 | 12:13h | UTC

Breastfeeding and the Use of Human Milk – Pediatrics

News Release: American Academy of Pediatrics Calls for More Support for Breastfeeding Mothers Within Updated Policy Recommendations

How to write statistical analysis section in medical research.

29 Jun, 2022 | 12:03h | UTC

How to write statistical analysis section in medical research – Journal of Investigative Medicine

Commentary on Twitter

How to write statistical analysis section in medical research
Via @JIM_AFMR https://t.co/1lfbiPlcel pic.twitter.com/6LZaLT7AGl

— Abraham E. Gracia R. (@Abraham_RMI) June 27, 2022

Under a http://creativecommons.org/licenses/by-nc/4.0/ license

Perspective | Fast-evolving COVID variants complicate vaccine updates.

29 Jun, 2022 | 12:01h | UTC

Fast-evolving COVID variants complicate vaccine updates – Nature

M-A: Comparison of mortality and hospital readmissions among patients receiving virtual ward transitional care vs. usual postdischarge care.

29 Jun, 2022 | 12:06h | UTC

Comparison of Mortality and Hospital Readmissions Among Patients Receiving Virtual Ward Transitional Care vs Usual Postdischarge Care: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary on Twitter

In this systematic review and meta-analysis of 24 RCTs, post-discharge virtual ward care was associated with reduced all-cause mortality, hospital readmission, and healthcare costs in patients with heart failure. https://t.co/yMx7F52L5S

— JAMA Network Open (@JAMANetworkOpen) June 28, 2022