Editor's Choice
M-A | Incidence and mortality of non-AIDS-defining cancers among people living with HIV.
23 Aug, 2022 | 13:26h | UTCRelated: Study: Cancer Patients with HIV Infection Have Worse Outcomes
M-A | Incubation period of COVID-19 caused by unique SARS-CoV-2 strains.
23 Aug, 2022 | 13:24h | UTC
WHO makes new recommendations for Ebola treatments, calls for improved access.
22 Aug, 2022 | 12:26h | UTCNews Release: WHO makes new recommendations for Ebola treatments, calls for improved access – World Health Organization
Guideline: Therapeutics for Ebola virus disease – World Health Organization
Commentary on Twitter (thread – click for more)
WHO publishes its first guideline for #Ebola virus disease therapeutics: recommends the use of two monoclonal antibodies.
WHO calls on the global community to increase access to these lifesaving medicines.
📌 https://t.co/tstO3pBYlf pic.twitter.com/ZrDg43TyL2
— World Health Organization (WHO) (@WHO) August 19, 2022
Guideline Summary | Recommendations for the outpatient drug treatment of patients with COVID-19.
22 Aug, 2022 | 12:25h | UTC
AHA Scientific Statement | Cardiovascular effects of home dialysis therapies.
22 Aug, 2022 | 12:24h | UTCTop Things to Know: CV Effects of Home Dialysis Therapies – American Heart Association
Commentaries:
AHA Urges More Home-Based Dialysis in Advanced Kidney Failure – TCTMD
Commentary on Twitter (thread – click for more)
https://twitter.com/bourneauguste/status/1559172680087228416
Consensus Statement | Preoperative management of medications for rheumatologic and HIV diseases.
22 Aug, 2022 | 12:22h | UTCRelated:
Preoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings
Preoperative Management of Surgical Patients Using Dietary Supplements – Mayo Clinic Proceedings
Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings
Preoperative Cardiac Risk Assessment – Mayo Clinic Proceedings
Preoperative Evaluation Before Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Cardiac Risk Reduction in Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings
Editorial | Rise of intravenous nutrition products among professional team sport athletes: reasons to be concerned?
22 Aug, 2022 | 12:20h | UTCRise of intravenous nutrition products among professional team sport athletes: reasons to be concerned? – British Journal of Sports Medicine (free for a limited period)
News Release: IV nutrition risks becoming the norm for athletes, despite no evidence it works – BMJ Newsroom
Commentary: More Athletes Are Getting Their Nutrition Through an IV. This Should Stop, Experts Say – HealthDay
Commentary on Twitter
IV nutrition risks becoming the norm for athletes, despite no evidence it works, warn @pedlarcr and colleagues in @BJSM_BMJ https://t.co/RRou2U8u9x
Used to be considered treatment of ‘last resort’
‘Food first’ and ‘no needle’ messages need to be amplified, urge experts pic.twitter.com/XeaRyHiVEH— BMJ Group (@bmj_company) August 17, 2022
RCT | Synthetic sling vs. artificial urinary sphincter for men with urodynamic stress incontinence after prostate surgery.
22 Aug, 2022 | 12:18h | UTC
RCT | Effectiveness of an intervention for reducing sitting time and improving health in office workers.
22 Aug, 2022 | 12:19h | UTCEditorial: The importance of sitting less and moving more – The BMJ
News Release: Standing desks alongside other measures cut office workers’ sitting time by an hour a day – BMJ Newsroom
Commentary: SMART Work and Life Intervention Reduces Sitting Time for Office Workers – HealthDay
Commentary on Twitter
Using a standing desk alongside a package of other measures to encourage office workers to sit less and move more, reduced sitting time by about an hour a day over one year, finds a trial published in @bmj_latest today https://t.co/uxaDWnp5WB
— The BMJ (@bmj_latest) August 18, 2022
RCT | Surgical reconstruction is superior to rehabilitation for patients with non-acute anterior cruciate ligament injury with persistent symptoms of instability.
22 Aug, 2022 | 12:16h | UTC
Commentary on Twitter
Surgical reconstruction of non-acute ACL injury with persistent symptoms of instability was superior in comparison with rehabilitation at 18 months (KOOS4 mean difference 7.9 (95% CI 2.5–13.2)): https://t.co/y2taBzHolU pic.twitter.com/n0qW3B6cMv
— Søren T. Skou (@STSkou) August 19, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
How to improve intubation in the intensive care unit | Update on knowledge and devices.
22 Aug, 2022 | 12:15h | UTCHow to improve intubation in the intensive care unit. Update on knowledge and devices – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
Tracheal intubation in #ICU
➡️ preoxygenation & apneic oxygenation
➡️ devices for ETT positioning & airway management algorithms
➡️ tube position confirmation
➡️ hemodynamic optimization/choice of drugs
➡️ bundle to limit complications #FOAMcc @yourICM
📎 https://t.co/Bn5F5aRsHK pic.twitter.com/vWgJh5z8Vl— Intensive Care Medicine (@yourICM) August 20, 2022
Cross-Sectional Study | Hypertension common among poorest, least educated around the world.
22 Aug, 2022 | 12:14h | UTCThe Association of Socioeconomic Status With Hypertension in 76 Low- and Middle-Income Countries – Journal of the American College of Cardiology (link to abstract – $ for full-text)
News Release: Hypertension Common Among Poorest, Least Educated Around the World – American College of Cardiology
Commentary: Hypertension Common Among Poorest, Least Educated Globally – HealthDay
Commentary on Twitter
#HTN is a common condition in low- & middle-income countries. As countries develop economically, these groups may experience a greater #hypertension prevalence relative to those w/ ⬆️ socioeconomic status. Read more on this important work now out in #JACC: https://t.co/sOzb1aWRvk pic.twitter.com/w00raCmuCW
— JACC Journals (@JACCJournals) August 16, 2022
AHA Scientific Statement outlines the most common symptoms of 6 cardiovascular diseases.
19 Aug, 2022 | 16:19h | UTCNews Release: Report outlines most common symptoms of 6 cardiovascular diseases – American Heart Association
Top Things to Know: State of the Science: The Relevance of Symptoms in CVD and Research – American Heart Association
Study | Almost half of global cancer deaths are due to risk factors, with smoking, alcohol use, and high BMI the greatest contributors.
19 Aug, 2022 | 16:21h | UTC
Commentary on Twitter (thread – click for more)
NEW #GBDstudy research from 2010-2019 found that a majority of attributable #Cancer DALYs globally were from behavioral risk factors. The top 3 behavioral risk factors for cancer burden were: #smoking 🚬, #alcohol 🍺, & high #BMI. @TheLancet »https://t.co/qPzDKzfLda pic.twitter.com/LnkvlkDHgA
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) August 18, 2022
Retrospective cohort study | Symptoms and risk factors for long COVID in non-hospitalized adults.
19 Aug, 2022 | 16:17h | UTCSymptoms and risk factors for long COVID in non-hospitalized adults – Nature Medicine
Commentary: UK study finds over 100 symptoms of long COVID in non-hospitalized adults – News Medical
M-A | The accuracy of pulse oximetry in measuring oxygen saturation by levels of skin pigmentation.
19 Aug, 2022 | 16:15h | UTCRelated:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Consensus Guideline | Preventing unrecognized esophageal intubation.
19 Aug, 2022 | 16:16h | UTC
Commentary on Twitter
🔐New #FreeForever @UniversalAirway guidelines!@NicholasChrimes @AndyHiggsGAA @CarinHagberg @PaulBakerORSIM @gaspasser @jadamlaw @hypoxicchicken @SheilaMyatra @ProfEllenO @AirwayOnDemand @crossermed @JohnCSakles @SorbelloMax @doctimcook
🔗https://t.co/UkOWKhFyBG pic.twitter.com/rnvEdsgRDs
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) August 18, 2022
RCT | A lower glycemic criteria in not better than higher glycemic criteria for the diagnosis of gestational diabetes.
18 Aug, 2022 | 13:04h | UTCLower versus Higher Glycemic Criteria for Diagnosis of Gestational Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Pros and cons with lower vs higher threshold for gestational diabetes diagnosis – medwire News
Commentary on Twitter (thread – click for more)
1/ Overdiagnosis of Gestational Diabetes (GDM): New large randomized trial compared broader/narrower criteria -> NO improvement in mother/baby outcomes BUT x2 increase in % pregnant women labelled as GDM. Time to reconsider GDM testing – https://t.co/xrr0XrdhaZ
— Paul Glasziou (@PaulGlasziou) August 18, 2022
RCT | Metformin, Ivermectin, and Fluvoxamine are not beneficial for obese outpatients with Covid-19.
18 Aug, 2022 | 13:00h | UTCEditorial: Time to Stop Using Ineffective Covid-19 Drugs – New England Journal of Medicine
Commentary on Twitter
In this trial involving overweight or obese outpatients with Covid-19, investigators found that none of three repurposed drugs (metformin, ivermectin, and fluvoxamine) reduced the risk of serious disease. https://t.co/8sd6R7CDK6 pic.twitter.com/bPZ6zeuZSA
— NEJM (@NEJM) August 17, 2022
Executive Summary | Guidelines for adrenalectomy.
18 Aug, 2022 | 12:58h | UTCAmerican Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary – JAMA Surgery (free for a limited period)
Author interview: American Association of Endocrine Surgeons Guidelines for Adrenalectomy – JAMA
Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.
18 Aug, 2022 | 12:56h | UTCCommentaries:
Anal and oral sex spread monkeypox. Let’s talk about it. – Vox
Related:
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Commentary on Twitter
New Spanish study investigates clinical and virological characteristics of confirmed human #monkeypox among 181 patients: https://t.co/3twjOaAVT5 pic.twitter.com/bfRxhjhEFn
— The Lancet (@TheLancet) August 10, 2022
Retrospective cohort study | Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy.
18 Aug, 2022 | 12:51h | UTCNews Release: No link between COVID-19 vaccination in pregnancy and higher risk of preterm birth or stillbirth – British Medical Journal
Related:
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy – Nature Reviews Immunology
WHO Questions and Answers: COVID-19 vaccines and pregnancy.
COVID vaccines safely protect pregnant people: the data are in.
COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter
No link between covid-19 vaccination in pregnancy and higher risk of preterm birth or stillbirth, finds study in @bmj_latesthttps://t.co/XLgFeoWVsp
Findings can help guide decision making about #covid-19 #vaccination during #pregnancy pic.twitter.com/9Pxm0Yv2Mf
— BMJ Group (@bmj_company) August 18, 2022
M-A | Performance of confirmatory tests for diagnosing primary aldosteronism.
18 Aug, 2022 | 12:54h | UTC
Commentary on Twitter
https://twitter.com/HyperAHA/status/1559624529869160448
Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients.
18 Aug, 2022 | 12:49h | UTC
Commentary on Twitter
NEW—People with #COVID19 continue to face increased risks of some neurological and psychiatric conditions up to 2 years after infection, according to a study published in @TheLancetPsych: https://t.co/9fD5zMU3hE pic.twitter.com/8YhTKJ9v72
— The Lancet (@TheLancet) August 17, 2022
Guideline | Recommendation on instrument-based screening for depression during pregnancy and the postpartum period.
17 Aug, 2022 | 14:39h | UTCSee also: Canadian Task Force on Preventive Health Care page with summary and tools