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Dermatology

Oral antifungal medication for toenail onychomycosis

20 Jul, 2017 | 00:08h | UTC

Cochrane What is the best medication for a fungal infection of the toenail? – Cochrane Library (free)

Full review: Oral antifungal medication for toenail onychomycosis – Cochrane Library (link to abstract – $ for full-text)

Terbinafine probably leads to better cure rates than azoles, with the same risk of adverse events. Griseofulvin is no better and has more adverse effects than azoles.

 


Multidrug therapy for leprosy patients in Brazil

16 Jul, 2017 | 23:47h | UTC

Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): Results of an open label, randomized and controlled clinical trial, among multibacillary patients – PLOS One (free) (RT @Onisillos)

Related WHO reports: Operational Manual 2016 – Global Leprosy Strategy 2016−2020 (free) AND Global Leprosy Strategy 2016−2020: Accelerating towards a leprosy-free world (free)

“Shorter courses Rx possible for Leprosy: Very important result” (RT @dr_michaelmarks see Tweet)

 


Current Therapeutic Approach to Hypertrophic Scars

16 Jul, 2017 | 23:33h | UTC

Clinical Review: Current Therapeutic Approach to Hypertrophic Scars – Frontiers in Medicine (free)

 


Meningococcal vaccine may protect against gonorrhoea

11 Jul, 2017 | 19:10h | UTC

Effectiveness of a group B outer membrane vesicle meningococcal vaccine against gonorrhoea in New Zealand: a retrospective case-control study – The Lancet (link to abstract – $ for full-text)

Commentaries: More reason to use Meningococcal B vaccine – it could also cut the Clap – The Conversation (author’s commentary – free) AND Meningococcal Vaccine May Provide Immunity Against Gonorrhea – Medscape (free registration required) AND Meningitis vaccine may also cut risk of ‘untreatable’ gonorrhoea, study says – The Guardian (free)

 


Doxycycline may be a safer first option for treating a blistering skin condition

8 Jul, 2017 | 20:28h | UTC

Doxycycline may be a safer first option for treating a blistering skin condition – NIHR Signal (free)

Original Article: Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial – The Lancet (free) AND Editorial: Doxycycline: a first-line treatment for bullous pemphigoid? (free)

 


Herpes Zoster Increases the Risk of Stroke and Myocardial Infarction

5 Jul, 2017 | 15:26h | UTC

Herpes Zoster Increases the Risk of Stroke and Myocardial Infarction – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Does Shingles Increase the Risk of Heart Attack, Stroke? – American College of Cardiology, Latest in Cardiology (free) AND Shingles may up risk of heart attack, stroke – Reuters Health (free) AND Heart attack and stroke risk higher with shingles – OnMedica (free)

 


Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatites

3 Jul, 2017 | 17:18h | UTC

The Solution for Skin Ailments Could Be Right Under Your Nose – The New York Times (10 articles per month are free)

Original article: Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatites – Science Translational Medicine (link to abstract – $ for full-text)

“Modifying the skin’s own bacteria may lead to treatments for acne, eczema and other common ailments” (RT @NYTHealth see Tweet)

 


Variability in the diagnosis of invasive melanoma

29 Jun, 2017 | 12:38h | UTC

Pathologists’ diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study – The BMJ (free)

The BMJ Opinion: Joann Elmore: When diagnostic uncertainty hits home (free)

Commentaries: Concern over huge diagnostic variability for melanoma – OnMedica (free) Pathologists Often Misclassify Melanoma – Physician’s First Watch (free)

 


A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses

29 Jun, 2017 | 13:34h | UTC

A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Adding Antibiotics to Incision-and-Drainage of Small Skin Abscesses Helps – Physician’s First Watch (free) AND Antibiotics Improve Short-Term Outcomes for Simple Abscesses – Medscape (free registration required) AND Study finds benefit for antibiotic treatment of simple skin wounds – CIDRAP (free)

 


Moisturisers improve eczema symptoms and lessen the need for corticosteroids

29 Jun, 2017 | 00:32h | UTC

Moisturisers improve eczema symptoms and lessen the need for corticosteroids – NIHR Signal (free)

Original Article: Emollients and moisturisers for eczema – Cochrane Library (link to summary – $ for full-text)

 


Adverse Events Reported to the US Food and Drug Administration for Cosmetics and Personal Care Products

26 Jun, 2017 | 17:15h | UTC

Adverse Events Reported to the US Food and Drug Administration for Cosmetics and Personal Care Products – JAMA Internal Medicine (free)

Editorial: Cosmetics, Regulations, and the Public Health – Understanding the Safety of Medical and Other Products (free)

The JAMA Network – For the Media: How Many Adverse Events Are Reported to FDA for Cosmetics, Personal Care? (free)

Commentaries: More Health Problems Reported With Hair And Skin Care Products – NPR (free) AND The Hidden Dangers of Makeup and Shampoo – TIME (a few articles per month are free)

 


Topical antimicrobial agents for treating foot ulcers in people with diabetes

25 Jun, 2017 | 13:56h | UTC

Topical antimicrobial agents for treating foot ulcers in people with diabetes – Cochrane Library (link to summary – & for full-text)

“Topical antimicrobial dressing may increase foot ulcer healing in people with diabetes” (RT @CochraneUK see Tweet)

 


Artificial tanning devices: public health interventions to manage sunbeds

21 Jun, 2017 | 18:28h | UTC

Artificial tanning devices: public health interventions to manage sunbeds – World Health Organization (free)

News release: More can be done to restrict sunbeds to prevent increasing rates of skin cancer

 


Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma

18 Jun, 2017 | 16:06h | UTC

Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma – New England Journal of Medicine (link to abstract – $ for full-text)

Quick take video summary: Dissection or Observation for Sentinel-Node Metastasis (free)

Commentaries: Watch-and-Wait OK in Sentinel Node Positive Melanoma – MedPage Today (free registration required) AND Common Surgical Treatment for Melanoma Does Not Improve Patients’ Overall Survival, Study Shows – Cedars-Sinai Medical Center, via NewsWise (free)

 


The End of Human Doctors – The Bleeding Edge of Medical AI Research

14 Jun, 2017 | 00:42h | UTC

The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 1) – By Luke Oakden-Rayner (RT @pash22 see Tweet)

Original article: Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA (free)

See more on the impact of artificial intelligence in healthcare in our April 28th issue, see #1, and in our April 10th issue, see #8

 

The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 2) – By Luke Oakden-Rayner (RT @pash22 see Tweet)

Original article: Dermatologist-level classification of skin cancer with deep neural networks – Nature (link to abstract – $ for full-text)

See more on the impact of artificial intelligence in healthcare in our April 28th issue, see #1, and in our April 10th issue, see #8

 


Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis

25 May, 2017 | 14:53h | UTC

Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial – JAMA (Link to abstract – $ for full-text)

Commentaries: Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis – Medscape (free registration required) AND Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis – Physician’s First Watch (free)

 


Angioedema in the emergency department

25 May, 2017 | 14:46h | UTC

Angioedema in the emergency department: a practical guide to differential diagnosis and management – International Journal of Emergency Medicine (free) (RT @Gas_Craic see Tweet)

 


Pressure ulcer prevention and treatment

19 May, 2017 | 17:53h | UTC

Pressure ulcer prevention and treatment. Is ‘best practice’ evidence-based? – Cochrane Blogs: Evidence for Everyday Nursing (free) (RT @CochraneUK see Tweet)

Evidence for the treatment of pressure ulcers reviewed.

 


Switching to biosimilar

16 May, 2017 | 20:01h | UTC

Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

Commentary: Celltrion Healthcare: Lancet Publishes Full Data-Set from Influential NOR-SWITCH Study – Business Wire (free)

 


Diagnosis and management of psoriasis

17 Apr, 2017 | 13:52h | UTC

Diagnosis and management of psoriasis – Canadian Family Physician (free)

 


Here’s why one tech investor thinks some doctors will be ‘obsolete’ in five years

10 Apr, 2017 | 15:56h | UTC

Here’s why one tech investor thinks some doctors will be ‘obsolete’ in five years – CNBC (free) (RT @CMichaelGibson)

According to this point of view, radiologists will be the first ones that are affected by Artificial Intelligence. As we can see below, other specialists that work by interpreting medical images may follow, like dermatologists, ophthalmologists and pathologists.

See also: If You Look at X-Rays or Moles for a Living, AI Is Coming for Your Job – Wired (free) AND Adapting to Artificial Intelligence: Radiologists and Pathologists as Information Specialists – JAMA Viewpoint (free – and legal – PDF found with Unpaywall) AND Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA Internal Medicine (link to abstract – $ required for full-text) AND Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features – Nature(free) see commentary in Computers trounce pathologists in predicting lung cancer type, severity, researchers find – Science News (free)

 


The wound/burn guidelines – Japanese Dermatological Association

5 Apr, 2017 | 21:55h | UTC

The wound/burn guidelines – Japanese Dermatological Association (all guidelines are free)

Wounds in general / Guidelines for the diagnosis and treatment for pressure ulcers / Guidelines for the diagnosis and treatment for diabetic ulcer/gangrene / Guidelines for the management of skin ulcers associated with connective tissue disease/vasculitis / Guidelines for the management of lower leg ulcers/varicose veins / Guidelines for the management of burns

 


Surgeries are being performed with the patient awake

27 Mar, 2017 | 00:59h | UTC

Going Under the Knife, With Eyes and Ears Wide Open – New York Times (free access to 10 articles per month)

“More and more surgeries are being performed with the patient awake and looking on, for financial and medical reasons”.

 


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