Dermatology
[Abstract Only] Randomized Trial: Monoclonal Anti-IgE Antibody for Chronic Spontaneous Urticaria
7 Oct, 2019 | 00:47h | UTCLigelizumab for Chronic Spontaneous Urticaria – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Ligelizumab safely, effectively treats hives – MedicalXpress (free) AND Ligelizumab May Improve Response in Chronic Urticaria – Medscape (free registration required)
[Abstract Only] Cohort Study: Cool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns
2 Oct, 2019 | 01:53h | UTCCool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns: A Cohort Study of Two Thousand Four Hundred Ninety-five Children – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: Simple Cool Running Water Reduces Burn Severity in Children – Journal Feed (free)
Review: Understanding Acute Burn Injury as a Chronic Disease
30 Sep, 2019 | 00:47h | UTCUnderstanding acute burn injury as a chronic disease – Burns & Trauma (free)
#ESMO19 – [Abstract Only] Randomized Trial: Improved Overall Survival at 5 Years with Combined Immunotherapy for Advanced Melanoma
30 Sep, 2019 | 00:37h | UTCFive-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Skin cancer: Half of people surviving advanced melanoma – BBC (free) AND Combination immunotherapy drugs herald new hope for melanoma patients with long term survival rates – The Royal Marsden NHS Foundation Trust (free)
#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona
Related Commentary on Twitter
With a 5-year min follow-up, the combination of nivolumab plus ipilimumab associated with 5-year survival of 52% in patients with metastatic #melanoma, compared with 44% for nivolumab alone and 26% for ipilimumab alone. See the CheckMate 067 trial. #ESMO19 https://t.co/f50KNzH5tp
— NEJM (@NEJM) September 28, 2019
Cohort Study: Improved Survival After Mohs Micrographic Surgery for Early-Stage Invasive Melanoma
30 Sep, 2019 | 00:12h | UTCComparison of Survival After Mohs Micrographic Surgery vs Wide Margin Excision for Early-Stage Invasive Melanoma – JAMA Dermatology (free for a limited period)
Editorial: Improving Survival for Patients With Early-Stage Melanoma (free for a limited period)
Commentaries: Mohs micrographic surgery may up survival in stage I melanoma – MedicalXpress (free) AND Mohs Tied to Better OS in Early Invasive Melanoma – MedPage Today (free registration required)
Related: Mohs Surgery for the Treatment of Skin Cancer: A Review of Guidelines – Canadian Agency for Drugs and Technologies in Health (free)
[Abstract Only] Study: Smartphone App for Triage of Skin Lesions Has a High Sensitivity in Detecting Skin Cancers
22 Sep, 2019 | 22:48h | UTCAccuracy of a smartphone application for triage of skin lesions based on machine learning algorithms – Journal of the European Academy of Dermatology and Venereology (link to abstract – $ for full-text)
Commentaries: Smart Phone App Uses Machine Learning to Triage Skin Cancers – MedicalResearch.com (free) AND SkinVision algorithm detects 95% of skin cancer, study finds – News Medical (free)
Review: Overview of Epidermoid Cyst
10 Sep, 2019 | 01:03h | UTCOverview of epidermoid cyst – European Journal of Radiology Open (free)
Guideline: Management of Chronic Urticaria in Children
18 Aug, 2019 | 21:34h | UTCManagement of chronic urticaria in children: a clinical guideline – Italian Journal of Pediatrics (free)
Related Guidelines: BSACI guideline for the management of chronic urticaria and angioedema (free) AND The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria (free) AND The diagnosis and management of acute and chronic urticaria: 2014 update – American Academy of Allergy, Asthma & Immunology (AAAAI) (free) AND ASCIA Chronic Spontaneous Urticaria (CSU) Position Paper and Treatment Guidelines (free)
Risk, Prevention, Diagnosis, and Management of Post-Operative Cutaneous Infection
11 Aug, 2019 | 21:15h | UTCRelated: Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free) AND Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery(free) AND Global guidelines on the prevention of surgical site infection – World Health Organization
Systematic Review: Screening for Melanoma is Not Supported or Refuted by Current Evidence
11 Aug, 2019 | 21:16h | UTCScreening for reducing morbidity and mortality in malignant melanoma – Cochrane Library (free)
Summary: Screening for malignant melanoma (a type of skin cancer) – Cochrane Library (free)
Featured Review: Evidence for the benefits and harms of screening for malignant melanoma – Cochrane Library (free)
Systematic Review: Interventions for Ulceration and Other Skin Changes Caused by Nerve Damage in Leprosy
2 Aug, 2019 | 01:02h | UTCInterventions for ulceration and other skin changes caused by nerve damage in leprosy – Cochrane Library (free)
Summary: Treatments for ulcers (wounds) and other skin changes in people with leprosy – Cochrane Library (free)
Systematic Review: Lifestyle Changes for Treating Psoriasis
2 Aug, 2019 | 01:01h | UTCLifestyle changes for treating psoriasis – Cochrane Library (free)
Related Commentary on Twitter
Lifestyle changes for treating #psoriasis – https://t.co/IqJHV5TDVE Cochrane Systematic Review includes RCTs with 1163 participants. Low‐calorie diet + exercise programme probably results in a greater reduction in the severity of psoriasis but effects vary. #skin
— The Cochrane Library (@CochraneLibrary) July 22, 2019
Joint AAD-NPF Guidelines of Care for the Management and Treatment of Psoriasis with Phototherapy
29 Jul, 2019 | 20:34h | UTCRelated: Guidelines on the Systemic Treatment of Psoriasis (several Guidelines on the subject)
Latin American Guidelines on the Systemic Treatment of Psoriasis
27 Jul, 2019 | 16:39h | UTC
Related Guidelines: Psoriasis: AAD Guidelines of Care with Awareness and Attention to Comorbidities (free) AND Psoriasis: assessment and management – National Institute for Health and Care Excellence (NICE) (free) AND European S3-Guideline on the systemic treatment of psoriasis vulgaris – European Academy of Dermatology and Venereology (free) AND Highlights of the updated Dutch evidence‐ and consensus‐based guideline on psoriasis 2017 – British Journal of Dermatology (free) AND Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of GPP – The Journal of Dermatology (free) AND French guidelines on the use of systemic treatments for moderate‐to‐severe psoriasis in adults – Journal of the European Academy of Dermatology and Venereology (free)
Penile Lesions: Patient Presentation, Differential Diagnosis, and Management
27 Jul, 2019 | 15:19h | UTCRelated Reviews: Penile warts: an update on their evaluation and management – Drugs in Context (free) AND Noninfectious Penile Lesions – American Family Physician (free)
Clinical Guide and Update on Porphyrias
26 Jul, 2019 | 01:11h | UTCClinical Guide and Update on Porphyrias – Gastroenterology (free)
Related Reviews: Update review of the acute porphyrias – British Journal of Haematology (free) AND Acute Hepatic Porphyrias: Review and Recent Progress – Hepatology Communications (free) AND Acute hepatic porphyrias: Recommendations for evaluation and long‐term management – Hepatology (free) AND An overview of the cutaneous porphyrias – F1000 Research (free)
Opinion: Antidepressants an Ace in the Hole for Urticaria
25 Jul, 2019 | 01:23h | UTCWhat to D.O. Antidepressants an Ace in the Hole for Urticaria – Emergency Medicine News (free)
[Abstract Only] Randomized Trial: 2-cm vs. 4-cm Surgical Excision Margins for Cutaneous Melanoma Thicker than 2 mm
24 Jul, 2019 | 02:10h | UTC2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Does Size of Surgical Excision Margins for Thick Localized Cutaneous Melanoma Affect Survival Outcomes? – The ASCO Post (free) AND Quick Take: 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm – 2 Minute Medicine (free)
Related Commentary on Twitter
In randomized study of 2 cm vs 4 cm margins for patients with thick (>2 mm) localised cutaneous melanoma, at 19.6 years of follow up, the narrow excision margin was as oncologically effective as the wider margin.: https://t.co/orX2wnLbnb #melsm #surgonc
— NatureRevClinOncol (@NatRevClinOncol) July 12, 2019
Guidelines for Epidermolysis Bullosa Laboratory Diagnosis
2 Jul, 2019 | 01:11h | UTC
Pathophysiology, Diagnosis, and Management of Infections in Atopic Dermatitis
2 Jul, 2019 | 01:04h | UTC
2019 European Guideline on the Management of Lymphogranuloma Venereum
30 Jun, 2019 | 18:07h | UTC
Clinical Update: Syphilis
30 Jun, 2019 | 17:53h | UTCSyphilis – The BMJ (free)
Related: WHO Guidelines for the Treatment of Treponema pallidum (Syphilis) – World Health Organization (free)
Update: Management of Metastatic Cutaneous Melanoma
30 Jun, 2019 | 17:21h | UTC
High Iron Status Could Lead to Greater Risk of Bacterial Skin Infections
21 Jun, 2019 | 07:43h | UTCCommentary: High on iron? It stops anaemia but has a downside – University of South Australia (free)
[Abstract Only] Artificial Intelligence Algorithms vs. Human Readers for Diagnosis of Pigmented Skin Lesions
17 Jun, 2019 | 01:38h | UTCComparison of the accuracy of human readers versus machine-learning algorithms for pigmented skin lesion classification: an open, web-based, international, diagnostic study – The Lancet Oncology (link to abstract- $ for full-text)
Commentary: Artificial intelligence for the diagnosis of skin lesions is superior to humans – Medical University of Vienna (free)