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Critical Care & Emergencies (all articles)

Consensus Statement | Aerosol therapy in adult critically ill patients

14 Jul, 2023 | 13:01h | UTC

Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support – Annals of Intensive Care

 


RCT | Swallowing and oral-care program enhances oral-feeding resumption and reduces pneumonia post-extubation

14 Jul, 2023 | 12:44h | UTC

Effects of a swallowing and oral-care program on resuming oral feeding and reducing pneumonia in patients following endotracheal extubation: a randomized, open-label, controlled trial – Critical Care

 


M-A | Adjunctive corticosteroids improve survival, clinical outcomes in severe community-acquired pneumonia

13 Jul, 2023 | 13:09h | UTC

Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia: a systematic review and meta-analysis of randomized controlled trials – Critical Care

Related:

Corticosteroids in Community-Acquired Bacterial Pneumonia: a Systematic Review, Pairwise and Dose-Response Meta-Analysis – Journal of General Internal Medicine (if the link is paywalled, try this one)

RCT | Hydrocortisone reduces mortality in severe community-acquired pneumonia

Effect of corticosteroids on mortality and clinical cure in community-acquired pneumonia: A systematic review, meta-analysis, and meta-regression of randomized control trials – CHEST

Corticosteroids for CAP, influenza and COVID-19: when, how and benefits or harm? – European Respiratory Review

ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia

 


Practice Guidance | Six steps to better care for older people in acute hospitals

12 Jul, 2023 | 14:00h | UTC

Six steps to better care for older people in acute hospitals – British Geriatrics Society

News Release: New guidance outlines ‘Six steps to better care for older people in hospital’ – British Geriatrics Society

 


Myocarditis: a primer for intensivists

12 Jul, 2023 | 13:42h | UTC

Myocarditis: a primer for intensivists – Intensive Care Medicine

 

Commentary on Twitter

 


Retrospective Analysis | 18% of ICU patients develop sepsis-associated AKI, mostly stage 1, diagnosed by low urine output

12 Jul, 2023 | 13:39h | UTC

Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter, observational study – Intensive Care Medicine

 

Commentary on Twitter

 


Review | Head to toe ultrasound: a narrative review of experts’ recommendations of methodological approaches

12 Jul, 2023 | 13:32h | UTC

Head to toe ultrasound: a narrative review of experts’ recommendations of methodological approaches – Journal of Anesthesia, Analgesia and Critical Care

 


AASLD Guidance | Use of TIPS, variceal embolization, and retrograde transvenous obliteration in variceal hemorrhage

11 Jul, 2023 | 13:59h | UTC

AASLD Practice Guidance on the Use of TIPS, Variceal Embolization, and Retrograde Transvenous Obliteration in the Management of Variceal Hemorrhage – Hepatology

 


Recommendations on the structure, personal, and organization of intensive care units

11 Jul, 2023 | 13:56h | UTC

Recommendations on the structure, personal, and organization of intensive care units – Frontiers in Medicine

News Release: German recommendations on the structure of intensive care units published internationally – Deutsche Interdisziplinäre Vereinigung für Intensiv

 


Subarachnoid hemorrhage | ED presentation, evaluation, and management

11 Jul, 2023 | 13:49h | UTC

Subarachnoid hemorrhage: ED presentation, evaluation, and management – emDocs

Related:

RCT | Use of lumbar drains improves 6-month outcomes in patients with aneurysmal subarachnoid hemorrhage

AHA/ASA Guideline for the management of patients with aneurysmal subarachnoid hemorrhage

Subarachnoid haemorrhage caused by a ruptured aneurysm: diagnosis and management – National Institute for Health and Care Excellence

Consensus Recommendations: Early management of patients with aneurysmal subarachnoid hemorrhage in a hospital with neurosurgical/neuroendovascular facilities.

Intracranial Pressure Monitoring and Management in Aneurysmal Subarachnoid Hemorrhage – Neurocritical Care

 


M-A | Catheter-directed thrombolysis vs. systemic thrombolysis and anticoagulation in intermediate- or high-risk pulmonary embolism

11 Jul, 2023 | 13:47h | UTC

Catheter-directed thrombolysis compared with systemic thrombolysis and anticoagulation in patients with intermediate- or high-risk pulmonary embolism: systematic review and network meta-analysis – Canadian Medical Association Journal

 


Review | Human-centered visualization technologies for patient monitoring are the future

11 Jul, 2023 | 13:34h | UTC

Human-centered visualization technologies for patient monitoring are the future: a narrative review – Critical Care

 


Practice Recommendation | Strategies to prevent MRSA transmission and infection in hospitals

10 Jul, 2023 | 14:02h | UTC

SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent methicillin-resistant Staphylococcus aureus transmission and infection in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

News Release: Updated guidance shows how hospitals should protect patients from resistant infections – Society for Healthcare Epidemiology of America

Commentary: New guidelines recommend antibiotic stewardship for preventing MRSA – CIDRAP

 


Guideline | Acute liver failure

10 Jul, 2023 | 13:59h | UTC

Acute Liver Failure Guidelines – The American Journal of Gastroenterology

Related:

EASL Clinical Practice Guidelines on acute-on-chronic liver failure – Journal of Hepatology

Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU

Acute-on-chronic liver failure: far to go—a review – Critical Care

 


RCT | Dual antiplatelet therapy proves noninferior to alteplase in minor ischemic stroke

10 Jul, 2023 | 13:58h | UTC

Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

See also: Visual Abstract

Commentary: ARAMIS Clinical Trial Demonstrates the Noninferiority of Dual Antiplatelet Therapy Compared with Intravenous Activase in Patients with Minor Nondisabling Acute Ischemic Stroke – Practical Neurology

 


Review | Evaluation of acute adult disorders of consciousness for the general intensivist

10 Jul, 2023 | 13:37h | UTC

State-of-the-Art Evaluation of Acute Adult Disorders of Consciousness for the General Intensivist – Critical Care Medicine (free for a limited period)

 


Personalized nutrition therapy in critical care: 10 expert recommendations

10 Jul, 2023 | 13:36h | UTC

Personalized nutrition therapy in critical care: 10 expert recommendations – Critical Care

 


How to avoid harm with feeding critically ill patients: a synthesis of viewpoints of a basic scientist, dietitian and intensivist

10 Jul, 2023 | 13:34h | UTC

How to avoid harm with feeding critically ill patients: a synthesis of viewpoints of a basic scientist, dietitian and intensivist – Critical Care

 


Consensus Paper | Adult cardiac surgery-associated acute kidney injury

7 Jul, 2023 | 16:18h | UTC

Adult Cardiac Surgery-Associated Acute Kidney Injury: Joint Consensus Report – Journal of Cardiothoracic and Vascular Anesthesia

 


Consensus Paper | The place of new antibiotics for Gram-negative bacterial infections in intensive care

7 Jul, 2023 | 16:15h | UTC

The place of new antibiotics for Gram-negative bacterial infections in intensive care: report of a consensus conference – Annals of Intensive Care

 


Review | Acute-on-chronic liver failure

7 Jul, 2023 | 16:09h | UTC

Acute-on-chronic liver failure: far to go—a review – Critical Care

Related:

EASL Clinical Practice Guidelines on acute-on-chronic liver failure – Journal of Hepatology

Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU

 


M-A | Clinical tests for confirming tracheal intubation or excluding esophageal intubation

3 Jul, 2023 | 14:19h | UTC

Clinical tests for confirming tracheal intubation or excluding oesophageal intubation: a diagnostic test accuracy systematic review and meta-analysis – Anaesthesia

 


M-A | Higher versus lower blood pressure targets after cardiac arrest

3 Jul, 2023 | 14:18h | UTC

Higher versus lower blood pressure targets after cardiac arrest: Systematic review with individual patient data meta-analysis – Resuscitation

 


Review | Respiratory challenges and ventilatory management in different types of acute brain-injured patients

3 Jul, 2023 | 14:17h | UTC

Respiratory challenges and ventilatory management in different types of acute brain-injured patients – Critical Care

 


RCT | Substituting saline with balanced crystalloid solution reduces delayed graft function in kidney transplantation

30 Jun, 2023 | 14:56h | UTC

Summary: The BEST-Fluids study was a pragmatic, multicentre, double-blind, randomized controlled trial carried out across 16 hospitals in Australia and New Zealand, aimed at comparing the use of balanced crystalloid solution (Plasma-Lyte 148) and saline in deceased donor kidney transplantation. The sample size comprised of 808 participants, who were either adults or children of any age, with the primary outcome defined as delayed graft function (DGF) occurring within 7 days post-transplantation.

Findings from the trial revealed that the balanced crystalloid group experienced less DGF than the saline group, with 121 out of 404 participants (30%) and 160 out of 403 participants (40%), respectively. This result yields an adjusted relative risk of 0.74 and an adjusted risk difference of 10.1%.

The study suggests that balanced crystalloid solution significantly reduces the incidence of DGF compared to saline. As no significant safety concerns were raised during the trial, the researchers recommend the use of balanced crystalloid solution as the standard-of-care intravenous fluid in deceased donor kidney transplantation. However, the study doesn’t indicate any significant differences in graft failure or mortality rates, which calls for further research.

Article: Balanced crystalloid solution versus saline in deceased donor kidney transplantation (BEST-Fluids): a pragmatic, double-blind, randomised, controlled trial – The Lancet (free registration required)

 


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