Critical Care & Emergencies (all articles)
European guidelines on perioperative venous thromboembolism prophylaxis
11 Nov, 2017 | 19:14h | UTCEuropean guidelines on perioperative venous thromboembolism prophylaxis (free PDF articles):
– Patients with preexisting coagulation disorders and after severe perioperative bleeding
– Cardiovascular and thoracic surgery
– Surgery in the obese patient
– Surgery during pregnancy and the immediate postpartum period
– Day surgery and fast-track surgery
– Chronic treatments with antiplatelet agents
– Aspirin
Meta-analysis: Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults
11 Nov, 2017 | 19:09h | UTCVancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Vancomycin plus piperacillin-tazobactam associated with higher AKI risk – ACP Hospitalist (free)
Related article: Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children – JAMA Pediatrics (link to abstract – $ for full-text)
2017 American Heart Association Focused Updates on Cardiopulmonary Resuscitation
11 Nov, 2017 | 17:16h | UTCNews Release and Summary: More Cardiac Arrest Victims Could Survive with Dispatcher CPR Instruction, Rescue Breaths for Children (free)
See Guidelines: 2017 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations Summary (free PDF) AND 2017 American Heart Association Focused Update on Adult Basic Life Support and Cardiopulmonary Resuscitation Quality (free PDF) AND 2017 American Heart Association Focused Update on Pediatric Basic Life Support and Cardiopulmonary Resuscitation Quality (free PDF)
Top Ten Things to Know: AHA Focused Update on Adult and Pediatric Basic Life Support and CPR Quality (free PDF)
Meta-analysis – Tranexamic acid: is it about time?
11 Nov, 2017 | 17:14h | UTCCommentaries: Tranexamic acid: is it about time? – The Lancet (free) Rapid use of blood drug could save thousands of lives, study finds – The Guardian (free) AND Severely bleeding patients must receive lifesaving drug within minutes, not hours – London School of Hygiene & Tropical Medicine, via EurekAlert (free)
Systematic Review: Glucocorticosteroids for people with alcoholic hepatitis
6 Nov, 2017 | 14:30h | UTCGlucocorticosteroids for people with alcoholic hepatitis – Cochrane Library (free)
Original article: Glucocorticosteroids for people with alcoholic hepatitis – Cochrane Library (link to abstract – $ for full-text)
“We found no evidence of a difference between glucocorticosteroids and placebo or no intervention on all-cause mortality, health-related quality of life, and serious adverse events during treatment”.
Research: Balanced Crystalloids vs Saline for Critically Ill Adults
5 Nov, 2017 | 20:38h | UTCBalanced Crystalloids vs Saline for Critically Ill Adults – American College of Chest Physicians Annual Meeting (free abstract)
Related Study: Balanced Crystalloids vs Saline for Noncritically Ill Adults in the Emergency Department – American College of Chest Physicians Annual Meeting (free abstract)
Commentaries: Landmark Trials Deliver Evidence to Rethink Saline Use – Medscape (free registration required) AND Saline on the Ropes? Studies find balanced crystalloid fluids safer – MedPage Today (free registration required)
Guideline: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke
5 Nov, 2017 | 20:36h | UTCCommentary: Intracranial Hemorrhage After Stroke Thrombolysis: More Questions Than Answers (free)
Top Ten Things to Know: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke (free PDF)
Slide Set: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in AIS (free PDF)
Related AHA/ASA Guidelines: Guidelines for the Early Management of Patients With Acute Ischemic Stroke (free) AND Guidelines for the Management of Spontaneous Intracerebral Hemorrhage (free)
Research: Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams
5 Nov, 2017 | 20:08h | UTCOriginal article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Updated WHO recommendation on intravenous tranexamic acid for the treatment of post-partum haemorrhage
5 Nov, 2017 | 20:08h | UTC
Review: Point of Care Ultrasound
5 Nov, 2017 | 19:57h | UTCPoint of Care Ultrasound: An Overview – American College of Cardiology, Latest in Cardiology (free)
Related reviews: Ultrasonography in the emergency department – Critical Care (free) AND Clinically integrated multi-organ point-of-care ultrasound for undifferentiated respiratory difficulty, chest pain, or shock: a critical analytic review – Journal of Intensive Care (free) AND Common pitfalls in point-of-care ultrasound: a practical guide for emergency and critical care physicians – Critical Ultrasound Journal (free) AND Point-of-Care Ultrasonography by Pediatric Emergency Medicine Physicians – Pediatrics (free)
Research: PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock
5 Nov, 2017 | 19:36h | UTCEditorial: Back to the Future in Cardiogenic Shock — Initial PCI of the Culprit Lesion Only (free)
Commentaries: CULPRIT-SHOCK Disputes Benefit of Immediate Multivessel PCI in Patients With Cardiogenic Shock – TCTMD (free) AND CULPRIT-SHOCK: Culprit Lesion Only PCI Vs. Immediate Multivessel PCI in Cardiogenic Shock – American College of Cardiology, Latest in Cardiology (free)
Guideline for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
5 Nov, 2017 | 19:37h | UTCNews release: Societies Detail Treatment for Patients With Ventricular Arrhythmias (free)
See also: Executive summary (free PDF) AND Top Ten Things to Know (free PDF) AND Slide Set (free PDF)
Review – So you think it is sepsis: considerations beyond lung and urine in the sick patient without a source
5 Nov, 2017 | 19:27h | UTC
Review: Acute Management of Pulmonary Embolism
5 Nov, 2017 | 19:17h | UTCAcute Management of Pulmonary Embolism – American College of Cardiology, Latest in Cardiology (free)
Review: The Practice and Implications of Finding Fluid During Point-of-Care Ultrasonography
29 Oct, 2017 | 01:21h | UTCRelated JAMA Video: Finding Fluid With Point-of-Care Ultrasonography (free)
Systematic review: Aerosol delivery during invasive mechanical ventilation
29 Oct, 2017 | 01:05h | UTCAerosol delivery during invasive mechanical ventilation: a systematic review – Critical Care (free)
Head position after acute stroke does not affect disability outcomes
29 Oct, 2017 | 00:50h | UTCHead position after acute stroke does not affect disability outcomes – NIHR Signal (free)
Original article: Cluster-Randomized, Crossover Trial of Head Positioning in Acute Stroke – The New England Journal of Medicine (link to abstract – $ for full-text)
Review: The challenge of Takotsubo syndrome
29 Oct, 2017 | 00:06h | UTCThe challenge of Takotsubo syndrome: heterogeneity of clinical features – Swiss Medical Weekly (free)
Carefully managed antibiotic use could halve antibiotic-resistant infections
23 Oct, 2017 | 20:38h | UTCCarefully managed antibiotic use could halve antibiotic-resistant infections – NIHR Signal (free)
Original article: Effect of antibiotic stewardship on the incidence of infection and colonisation with antibiotic-resistant bacteria and Clostridium difficile infection: a systematic review and meta-analysis – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Meta-analysis: High-flow oxygen via nasal cannulae in patients with acute hypoxemic respiratory failure
21 Oct, 2017 | 18:20h | UTC“In patients with acute hypoxemic respiratory failure HFNC was not associated with a difference in mortality compared to Noninvasive ventilation or standard oxygen”
Guidelines for supportive care of patients with Ebola virus disease
21 Oct, 2017 | 18:18h | UTCEvidence-based guidelines for supportive care of patients with Ebola virus disease – The Lancet (free)
Commentaries: New Ebola guidelines address immediate supportive care – CIDRAP (free)
Guideline: Update to Practice Standards for Electrocardiographic Monitoring in Hospital Settings
21 Oct, 2017 | 18:14h | UTCCommentaries: 12 key points to remember: Standards for Inpatient Electrocardiographic Monitoring – American College of Cardiology, Latest in Cardiology (free) AND AHA updates practice standards for electrocardiographic monitoring – ACP Hospitalist (free)
Research: Receipt of Blood Transfusion From Previously Pregnant Donor Associated with Increased Risk of Death Among Male Recipients
21 Oct, 2017 | 17:33h | UTCAssociation of Blood Transfusion From Female Donors With and Without a History of Pregnancy With Mortality Among Male and Female Transfusion Recipients – JAMA (link to abstract – $ for full-text)
Commentaries: Blood Boundaries: Should Transfusions Be Matched by Sex? – Scientific American (free) AND Are transfusions harmful to men if the blood comes from women who have been pregnant? – STAT (free) AND Receipt of Blood Transfusion From Previously Pregnant Donor Associated with Increased Risk of Death Among Male Recipients – The JAMA Network (free)
Systematic review: Testing blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections
17 Oct, 2017 | 19:00h | UTCOriginal Article: Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections – Cochrane Library (link to abstract – $ for full-text)
“the use of procalcitonin to guide initiation and duration of antibiotic treatment results in lower risks of mortality, lower antibiotic consumption, and lower risk for antibiotic-related side effects”.
Older people with acute coronary syndromes may benefit from routine invasive therapy
17 Oct, 2017 | 19:02h | UTCOlder people with acute coronary syndromes may benefit from routine invasive therapy – NIHR Signal (free)
Original article: Revascularisation compared with initial medical therapy for non-ST-elevation acute coronary syndromes in the elderly: a meta-analysis – Heart (link to abstract – $ for full-text)