Critical Care & Emergencies (all articles)
Opinion: Epinephrine Harms/Helps in Out of Hospital Cardiac Arrest
26 Jul, 2018 | 17:55h | UTCParamedic 2: Epinephrine harms/helps in out of hospital cardiac arrest – First10EM (free)
See Also: Original Article (free study and editorial) AND Expert Reaction (free commentaries)
“Paramedic 2 quick summary:
If 1000 people treated with epinephrine:
– 246 extra ROSC (return of spontaneous circulation)
– 158 extra admissions
– 8 extra survivors (5 with bad neuro outcomes, 3 with good neuro outcomes)
– What those numbers mean is a value question, not a science question.” (via @First10EM see Tweet)
Review: Definitions and Pathophysiology of Vasoplegic Shock
26 Jul, 2018 | 17:51h | UTCDefinitions and pathophysiology of vasoplegic shock – Critical Care (free)
Review: Advances in Understanding and Managing Acute Pancreatitis
26 Jul, 2018 | 17:33h | UTCRecent advances in understanding and managing acute pancreatitis – F1000 Research (free)
Expert Reaction to Trial Looking at Adrenaline for Cardiac Arrests
20 Jul, 2018 | 03:32h | UTCExpert reaction to trial looking at adrenaline for cardiac arrests – Science Media Centre (free)
See original article in yesterday’s issue: A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest (see #1)
Related Review: The role of adrenaline in cardiopulmonary resuscitation – Critical Care (free)
Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest
20 Jul, 2018 | 03:19h | UTCEditorial: Testing Epinephrine for Out-of-Hospital Cardiac Arrest (free)
Commentary: Using adrenaline in cardiac arrests results in less than 1 percent more people leaving hospital alive – University of Warwick, via EurekAlert (free)
See also: Infographic detailing result findings (free)
“A clinical trial of the use of adrenaline in cardiac arrests has found that its use results in less than 1% more people leaving hospital alive – but almost doubles the risk of severe brain damage for survivors of cardiac arrest” (from University of Warwick).
Review: Auscultation for Bowel Sounds in Patients with Ileus
20 Jul, 2018 | 02:46h | UTCEditorial: It’s not a gut feeling: don’t listen to the bowels (free PDF)
Source: Critical Care Reviews Newsletter
Review: Noninvasive Ventilation in Acute Respiratory Failure
20 Jul, 2018 | 02:47h | UTCSource: Critical Care Reviews Newsletter
Study: Overprescription of Antibiotics in Urgent Care Clinics
20 Jul, 2018 | 02:43h | UTCComparison of Antibiotic Prescribing in Retail Clinics, Urgent Care Centers, Emergency Departments, and Traditional Ambulatory Care Settings in the United States – JAMA Internal Medicine (free for a limited period)
Commentaries: Overprescription in Urgent Care Clinics—The Fast and the Spurious – JAMA Internal Medicine (free for a limited period) AND Urgent care centers often prescribe unnecessary antibiotics – Reuters (free) AND Study spotlights inappropriate prescribing in urgent care – CIDRAP (free)
Cohort Study: Inferior Vena Cava Filters and Mortality in Patients with Contraindication to Anticoagulation
20 Jul, 2018 | 02:17h | UTCCommentaries: Inferior Vena Cava Filters and Mortality: Is It the Underlying Process, the Patient, or the Device? (free)
“Could IVC filters be causing harm? They began being used before @US_FDA started approving devices. This article raises possibility of increased mortality. Maybe where we need trials to determine safety and effectiveness”. (via @hmkyale see Tweet)
Guideline: Management of Non ST-segment Elevation Acute Coronary Syndrome
20 Jul, 2018 | 02:14h | UTCRelated Guidelines: 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation (free) AND 2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes (free)
Expert Consensus: Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction
20 Jul, 2018 | 02:13h | UTC
Study: Safety Planning Intervention With Follow-up vs Usual Care of Suicidal Patients
13 Jul, 2018 | 03:05h | UTCComparison of the Safety Planning Intervention With Follow-up vs Usual Care of Suicidal Patients Treated in the Emergency Department – JAMA Psychiatry (free for a limited period)
Author Interview: Association of Safety Planning Intervention With Subsequent Suicidal Behavior Among ER-Treated Suicidal Patients (free)
Commentaries: ED Intervention with Follow-Up Appears to Reduce Suicidal Behaviors – NEJM Physician’s First Watch (free) AND A Simple Emergency Room Intervention Can Help Cut Suicide Risk – NPR (free)
Related Studies: Suicide Prevention in an Emergency Department Population (free study and commentaries) AND Strategies to prevent death by suicide (link to abstract and commentaries)
Randomized Trial: Alteplase vs Aspirin for Patients with Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits
13 Jul, 2018 | 02:58h | UTCEffect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits: The PRISMS Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Stopping the Alteplase Indication Creep – Emergency Medicine Literature of Note (free) AND Alteplase unlikely to reduce disability after mild stroke without disabling deficits – 2 Minute Medicine (free) AND Lytic No Better Than Aspirin for Mild Ischemic Stroke – MedPage Today (free registration required)
Summary of the International Guidelines for the Management of Hospital-acquired and Ventilator-acquired Pneumonia
13 Jul, 2018 | 02:38h | UTCEditorial: Treating nosocomial pneumonia: what’s new (free)
Related Guidelines: International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia – European Respiratory Journal (free) AND Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society – Clinical Infectious Diseases (free)
Source: Critical Care Reviews Newsletter
NICE Draft Guidance: Antibiotics Should be Restricted for COPD
13 Jul, 2018 | 02:36h | UTCAntibiotics should be restricted for COPD – National Institute for Health and Care Excellence (free)
Commentaries: Antibiotics should be restricted for COPD, says NICE – OnMedica (free) AND UK officials recommend limits on antibiotics for COPD – CIDRAP (free)
“The draft antimicrobial guidance recommends that antibiotics should be offered to people who have a severe flare up of symptoms, also known as a severe acute exacerbation”
Guideline: Management Of Acute Respiratory Distress Syndrome
13 Jul, 2018 | 02:29h | UTCGuidelines On The Management Of Acute Respiratory Distress Syndrome – Intensive Care Society (free PDF) (via @CritCareReviews)
Related Guidelines: The clinical practice guideline for the management of ARDS in Japan – Journal of Intensive Care (free) AND An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome (free)
Systematic Review: Effects of Hyperoxia in Acutely Ill Patients
13 Jul, 2018 | 02:19h | UTCRelated Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)
Source: Critical Care Reviews Newsletter
Review: Effects of Volume Overload and Current Techniques for the Assessment of Fluid Status in Patients with Renal Disease
13 Jul, 2018 | 01:38h | UTCSource: Critical Care Reviews Newsletter
Refractory Status Epilepticus: Pearls and Pitfalls for the Resuscitation Room
13 Jul, 2018 | 01:39h | UTCRefractory Status Epilepticus: Pearls and Pitfalls for the Resuscitation Room – emDocs (free)
Heart Failure: “Sneaky” Triggers and Clinical Pearls
13 Jul, 2018 | 01:23h | UTCHeart Failure: “Sneaky” Triggers and Clinical Pearls – emDocs (free)
Review: Perioperative Acute Kidney Injury
13 Jul, 2018 | 01:21h | UTCPerioperative Acute Kidney Injury: Prevention, Early Recognition, and Supportive Measures – Nephron (free)
Source: Critical Care Reviews Newsletter
Review: Assessment of Hypovolemia in the Critically Ill
13 Jul, 2018 | 01:19h | UTCAssessment of hypovolaemia in the critically ill – Anaesthesiology Intensive Therapy (free PDF)
Source: Critical Care Reviews Newsletter
Review: ICU Delirium ― A Diagnostic and Therapeutic Challenge in the Intensive Care Unit
13 Jul, 2018 | 01:18h | UTCSource: Critical Care Reviews Newsletter
Meta-Analysis: Recruitment Maneuver Does Not Provide any Mortality Benefit Over Lung Protective Strategy Ventilation in Adult Patients with ARDS
13 Jul, 2018 | 01:17h | UTCSource: Critical Care Reviews Newsletter
Randomized Trial: Point-of-Care Ultrasonography in Emergency Department Patients with Undifferentiated Hypotension
13 Jul, 2018 | 01:16h | UTCDoes Point-of-Care Ultrasonography Improve Clinical Outcomes in Emergency Department Patients With Undifferentiated Hypotension? An International Randomized Controlled Trial From the SHoC-ED Investigators – Annals of Emergency Medicine (link to abstract – $ for full-text)