Critical Care & Emergencies (all articles)
Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism
27 Mar, 2019 | 06:14h | UTCPregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: YEARS algorithm adaptation for pregnant women helped avoid CT scans for suspected PE – ACP Hospitalist (free) AND Pregnancy-adapted algorithm avoids diagnostic imaging for PE – MedicalXpress (free) AND PE in Pregnancy & YEARS Protocol – Emergency Medicine Literature of Note (free)
Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds?
27 Mar, 2019 | 05:56h | UTCTranexamic Acid (TXA) for Everything that Bleeds? – REBEL EM (free)
Related: Meta-analysis – Tranexamic acid: is it about time? (free study and commentaries) AND Randomized Controlled Trial: Tranexamic Acid for Hyperacute Primary Intracerebral Hemorrhage (free) AND Systematic Review: Tranexamic Acid for Patients with Epistaxis (free) AND Systematic Review: Antifibrinolytic drugs for treating primary postpartum haemorrhage (free) AND WHO Recommendation on Tranexamic Acid for the Treatment of Postpartum Haemorrhage (free) AND Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (free) AND Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial (landmark trial on the subject)
State of the Art Review: Management of Acute Upper Gastrointestinal Bleeding
26 Mar, 2019 | 01:56h | UTCManagement of acute upper gastrointestinal bleeding – The BMJ (free for a limited period)
Related Commentary on Twitter
Management of acute upper gastrointestinal bleeding: Clinical review summarizes evidence for risk assessment, resuscitation, blood transfusion, medical and endoscopic therapy, and early post-endoscopic management https://t.co/Cd6G8CzVN9 #BMJEducation #MedEd
— The BMJ (@bmj_latest) March 25, 2019
Thyrotoxicosis: Diagnosis and Management
26 Mar, 2019 | 01:43h | UTCThyrotoxicosis: Diagnosis and Management – Mayo Clinic Proceedings (free)
Related: Thyroid Storm: A Japanese Perspective (free study and commentary)
Opinion – “Things We Do for No Reason: Neuroimaging for Hospitalized Patients with Delirium”
25 Mar, 2019 | 00:26h | UTCSee Complete Series of Things We Do For No Reason (free articles)
Opinion – “Things We Do for No Reason: Use of Antipsychotic Medications in Patients with Delirium”
25 Mar, 2019 | 00:24h | UTCSee Complete Series of Things We Do For No Reason (free articles)
Randomized Trial: Ultrasound Guidance in Difficult Radial Artery Puncture for Blood Gas Analysis
22 Mar, 2019 | 06:57h | UTC
Systematic Review: Outpatient Management of Fever and Neutropenia in Patients with Cancer
20 Mar, 2019 | 03:17h | UTCOutpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event – Cochrane Library (free)
Summary: Outpatient treatment for cancer patient with low-risk febrile neutropaenic event is effective – Cochrane Library (free)
Related Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free)
Meta-Analysis: Point-of-Care Lung Ultrasonography vs. Chest Radiography in Adults with Symptoms Suggestive of Acute Decompensated Heart Failure
20 Mar, 2019 | 02:53h | UTC“The findings suggest that Lung Ultrasonography is more sensitive than Chest Radiography in detecting pulmonary edema in ADHF”.
Randomized Trial: Delayed vs. Immediate Coronary Angiography after Cardiac Arrest without ST-Segment Elevation
19 Mar, 2019 | 03:46h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Coronary Angiography after Cardiac Arrest without ST-Segment Elevation – New England Journal of Medicine (free for a limited period)
Editorial: Coronary Angiography after Cardiac Arrest — The Right Timing or the Right Patients? (free for a limited period)
Commentaries: Angiography timing does not impact survival after cardiac arrest for NSTEMI patients – American College of Cardiology (free) AND COACT: Delayed Angiography Does Not Compromise Survival in Cardiac Arrest Patients Without STEMI – TCTMD (free)
Related Commentary on Twitter
COACT: Among patients who had been successfully resuscitated after out-of-hospital cardiac arrest and had no signs of STEMI, a strategy of immediate angiography was not found to be better than a strategy of delayed angiography with respect to overall survival at 90 days. #ACC19
— NEJM (@NEJM) March 18, 2019
Randomized Trial: Early vs. Delayed Cardioversion in Recent-Onset Atrial Fibrillation
19 Mar, 2019 | 03:44h | UTCPresented at the European Heart Rhythm Association 2019 Congress.
Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation – New England Journal of Medicine (free for a limited period)
Editorial: The RACE to Treat Atrial Fibrillation in the Emergency Department (free for a limited period)
Commentary: For Acute A-fib, Wait-and-See Approach May Spare Many Patients from Cardioversion – TCTMD (free)
Related Commentary on Twitter
RACE 7 ACWAS: In patients presenting to the emergency department with recent-onset, symptomatic atrial fibrillation, a wait-and-see approach was noninferior to early cardioversion in achieving a return to sinus rhythm at 4 weeks. #EHRA2019 #Afib
— NEJM (@NEJM) March 18, 2019
Antimicrobial Prescription Guidelines in Critically Ill Immunocompromised Patients
19 Mar, 2019 | 03:20h | UTCSource: Critical Care Reviews Newsletter
Guidelines for Antibiotic Prescription in the Intensive Care Unit
19 Mar, 2019 | 03:24h | UTCSource: Critical Care Reviews Newsletter
Comprehensive guideline covering many common conditions in the Critical Care Unit.
Patient Blood Management Recommendations From the 2018 Frankfurt Consensus Conference
17 Mar, 2019 | 18:57h | UTCPatient Blood Management Recommendations From the 2018 Frankfurt Consensus Conference – JAMA (free for a limited period)
Cohort Study: High Sensitivity Cardiac Troponin May Result in Misdiagnosis of Acute Myocardial Infarction
17 Mar, 2019 | 18:58h | UTCCommentaries: Evaluate Troponin Results Carefully, Researchers Warn – NEJM Journal Watch (free) AND Blood test to diagnose heart attacks is flawed, warn researchers – The BMJ (free) AND CHARIOT: 1 in 20 Hospitalized Patients Undergoing Blood Tests Have Elevated Troponin – TCTMD (free)
Related: Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival (free study and commentaries)
Related Commentary on Twitter
This study found that the true 99th centile of high sensitivity cardiac troponin for a general hospital population was not consistent with the manufacturer's recommended upper limit of normal #BMJResearch @NickCurzen https://t.co/IQy62VenOx
— The BMJ (@bmj_latest) March 15, 2019
Review: Acute Respiratory Distress Syndrome
17 Mar, 2019 | 18:56h | UTCAcute Respiratory Distress Syndrome – Nature Reviews Disease Primer (free PDF)
Related Commentary on Twitter
Our article today "Acute respiratory distress syndrome" in Nature Reviews Disease Primer.
To access, click https://t.co/HWS7zqu0EAA privilege to work with M Matthay, R Zemans, G Zimmerman, J Beitler, A Mercat, M Herridge, A Randolph and C Calfee@kaimrc_ksa @KSAU_HS @NGHAnews pic.twitter.com/DMsKh0DbbC
— Yaseen Arabi (@YaseenarabiYa) March 14, 2019
Continuous Renal Replacement Therapy: Who, When, Why, and How
15 Mar, 2019 | 02:56h | UTCContinuous Renal Replacement Therapy: Who, When, Why, and How – Chest (free)
SIGN Guideline: Risk Reduction and Management of Delirium
14 Mar, 2019 | 00:52h | UTCRisk reduction and management of delirium – Scottish Intercollegiate Guidelines Network (SIGN) (free guideline and summary)
News Release: First delirium clinical guidelines for Scotland published on World Delirium Awareness Day (free)
Review: Clinical Assessment of Peripheral Tissue Perfusion in Septic Shock
14 Mar, 2019 | 00:47h | UTCRelated Research: Randomized Trial: Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels in Patients with Septic Shock (link to abstract $ for full-text)
Consensus Statement: Management of Adult Patients with Traumatic Brain Injury Receiving Oral Anticoagulant Therapy
12 Mar, 2019 | 13:01h | UTC
Meta-Analysis: Signs and Symptoms That Rule out Community-Acquired Pneumonia in Outpatient Adults
12 Mar, 2019 | 02:49h | UTCAdults with an acute respiratory infection who have normal vital signs (temperature < 37,8 / respiratory rate < 20 / heart rate < 100) and a normal pulmonary examination are very unlikely to have CAP.
AHA Statement on Cardiorenal Syndrome – Classification, Pathophysiology, Diagnosis, and Treatment Strategies
12 Mar, 2019 | 02:52h | UTCCommentary: The Heart-Kidney, Kidney-Heart Connection and Our Improving Understanding of a Complex and Intimate Relationship – American Heart Association (free)
Top Things to Know: Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies – American Heart Association (free)
Randomized Trial: Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection
11 Mar, 2019 | 03:56h | UTCAntiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: Antiplatelet and Anticoagulation Therapy May Equally Reduce Stroke Risk in Cervical Artery Dissection Patients – NeurologyToday (free)
Selected Articles from the Annual Update in Intensive Care and Emergency Medicine 2019
11 Mar, 2019 | 04:00h | UTCSelected Articles from the Annual Update in Intensive Care and Emergency Medicine 2019 – Critical Care (free articles)
– Sleep and Circadian Rhythm in Critical Illness
– Iron Metabolism: An Emerging Therapeutic Target in Critical Illness
– Heterogeneity in sepsis: new biological evidence with clinical applications
– Multidrug Resistant Gram-Negative Bacteria in Community-Acquired Pneumonia
– Uncovering Consciousness in Unresponsive ICU Patients: Technical, Medical and Ethical Considerations
– Mechanical Circulatory Support Devices for Cardiogenic Shock: State of the Art
– Physiological and Technical Considerations of Extracorporeal CO2 Removal
– ARDS in Obese Patients: Specificities and Management
– Recruitment Maneuvers and Higher PEEP, the So-Called Open Lung Concept, in Patients with ARDS
Systematic Review: Outpatient vs. Inpatient Treatment for Acute Pulmonary Embolism
8 Mar, 2019 | 04:52h | UTCOutpatient versus inpatient treatment for acute pulmonary embolism – Cochrane Library (free)
Summary: Outpatient versus inpatient treatment for acute pulmonary embolism – Cochrane Library (free)
Related: British Thoracic Society Guideline for the initial outpatient management of pulmonary embolism (free)